Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics
- 1st Edition - August 24, 2020
- Latest edition
- Editor: Allan Matte
- Language: English
Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approache… Read more
Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book.
- Covers the vital new area of R&D on therapeutic antibodies
- Written by leading scientists and researchers
- Up-to-date coverage and includes a detailed bibliography
Senior undergraduate or graduate courses in biotechnology, downstream processing or biotherapeutics R&D. It would also be a useful resource to industry scientists and managers in the areas of downstream processing and therapeutic antibody analysis and characterization
1. LC-MS characterization of antibody-based therapeutics: recent highlights and future prospects
2. Engineering of Protein A for improved purification of antibodies and Fc-fused proteins
3. High fidelity affinity purification of Fc-fusion molecules from product related impurities
4. Recent advances in continuous downstream processing of antibodies and related products
5. Recent advances in antibody-based monolith chromatography for therapeutic applications
6. Recent advances in harvest clarification for antibodies and related products
7. Recent advances in ultrafiltration and virus filtration for production of antibodies and related biotherapeutics
8. A roadmap for IgG-like bispecific antibody purification
9. High-throughput, parallelized and automated protein purification for therapeutic antibody development
2. Engineering of Protein A for improved purification of antibodies and Fc-fused proteins
3. High fidelity affinity purification of Fc-fusion molecules from product related impurities
4. Recent advances in continuous downstream processing of antibodies and related products
5. Recent advances in antibody-based monolith chromatography for therapeutic applications
6. Recent advances in harvest clarification for antibodies and related products
7. Recent advances in ultrafiltration and virus filtration for production of antibodies and related biotherapeutics
8. A roadmap for IgG-like bispecific antibody purification
9. High-throughput, parallelized and automated protein purification for therapeutic antibody development
- Edition: 1
- Latest edition
- Published: August 24, 2020
- Language: English
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Allan Matte
Allan Matte is a Senior Research Officer in the Downstream Processing Team in HHT. With over 30 years of involvement in scientific R&D, he has coauthored more than 70 original research articles, reviews, and book chapters in various areas of protein science. He has also presented at a number of national and international conferences in the areas of high-throughput structural biology and antibody purification
Affiliations and expertise
Human Health Therapeutics, Research Center, National Research Council Canada, Montreal, QC, CanadaRead Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics on ScienceDirect