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Histone Modifications in Therapy

  • 1st Edition, Volume 20 - August 21, 2020
  • Editors: Pedro Castelo-Branco, Carmen Jeronimo
  • Language: English
  • Paperback ISBN:
    9 7 8 - 0 - 1 2 - 8 1 6 4 2 2 - 8
  • eBook ISBN:
    9 7 8 - 0 - 1 2 - 8 1 6 7 4 0 - 3

Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease p… Read more

Histone Modifications in Therapy

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Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and inflammatory disorders, among others. In relation to these disease types, histone modifications are discussed, both as mechanisms of prevention and possible treatment.

A concluding chapter brings together future perspectives for targeting histone modifications in therapy and next steps in research.