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Elsevier

Books in Life sciences

  • Opiate Receptors and the Neurochemical Correlates of Pain

    Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979
    • 1st Edition
    • Susanna Fürst
    • English
    Opiate Receptors and the Neurochemical Correlates of Pain, Volume V, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. The congress offered a good opportunity to stimulate discussions and exchange of ideas between scientists from various countries who approach the problem of narcotics and pain mechanisms in different ways. The 27 contributions in this volume have enriched knowledge in this rapidly expanding field of pharmacology. This volume begins with a discussion of opiate receptors. The results suggest the interaction of various morphine-like drugs with different opiate receptor populations. The existence in nerve tissue of specific opiate receptors binding morphine and other opioids has led to the assumption of endogenous ligand for opiate receptors. One section of the present volume is devoted to enkephalins and endorphins, their structure-activity relationships, interactions with transmitter and other systems, their behavioral effects, and to factors controlling their release. Some other aspects of nociception; the pathways involved in the mode of action of different types of analgesics, e.g. narcotics and non-narcotics; and their relations to inflammation and active substances, such as prostaglandins and substance P, are discussed from various aspects.

  • Recent Advances in Liquid-Liquid Extraction

    • 1st Edition
    • C. Hanson
    • English
    Recent Advances in Liquid-liquid Extraction focuses on the applications of liquid extraction. The selection first discusses solvent extraction. Concerns include organic and inorganic separations, mass transfer process, solvent extraction economics, and coalescence in liquid-liquid systems. The book focuses on the chemistry of solvent extraction. Extraction by acidic organophosphorus compounds; extraction by phosphorus-bonded oxygen-donor solvents; extraction by high-molecular weight amines; and synergistic extraction are elaborated. The book also focuses on industrial organic processes; industrial contacting equipment; response characteristics and control of extraction processes; and calculation of contactors with longitudinal mixing. The selection presents the study of longitudinal mixing in liquid-liquid contactors. Rotating disc contactors, packed columns, vibrating plate extractors, and Oldshue-Rushton columns are described. The text also discusses heat transfer by direct liquid-liquid contact and the coalescence of liquid droplets and liquid dispersion. The selection is a vital source of data for readers interested in liquid extraction.

  • Electrophysiological Methods

    Physical Techniques in Biological Research
    • 1st Edition
    • William L. Nastuk
    • English
    Electrophysiological Methods presents a compilation of essays relating to the field of electricity. One topic is the introduction and analysis of electrical stimulation. Other types of stimulation are thermal stimulation, light stimulation, touch stimulation, and auditory stimulation. Microelectrodes act as links by which small regions in biological tissues are electrically joined to amplifying and recording devices. This topic is explored more thoroughly in the book. The physiological activity of cells in nerves, muscles, secretory organs, and other biological structures is accompanied by electrical changes which appear across the cell membrane. This occurrence is another topic in the text. Intracellular techniques employed to record transmembrane potentials and to stimulate cells are likewise presented. A section of the book presents microelectrophoresis which is a method wherein electrical flow is employed to manipulate the ejection of chemical substances from fine microelectrodes or micropipettes. The book will provide useful information to neurologist, cytologist, doctors, students, and researchers in the field of medicine.

  • Aminergic and Peptidergic Receptors

    Satellite Symposium of the 3rd Congress of the Hungarian Pharmacological Society, Szeged, Hungary, 1979
    • 1st Edition
    • E. S. Vizi + 1 more
    • English
    Advances in Pharmacological Research and Practice, Volume VII: Aminergic and Peptidergic Receptors focuses on how neurotransmitters, drugs, and hormones affect the plasma membrane. Composed of 14 chapters, the book outlines the manner by which presynaptic receptors involved in chemical neurotransmission function. The text then presents various laboratory experiments done to animals to determine how these receptors affect the plasma membrane of these subjects. One of the internal body parts examined is the heart. The variation in sensitivity of opiate receptors is also discussed, focusing on the effect of opioid peptides and morphine on the nigrostriatal axon terminals. The book also discusses the biochemical and pharmacological assets of opiate receptors among mollusks; the upshot of peptides upon biogenic amines of the central nervous system; and how gastrin analogues affect the gastrin receptor of the stomach. This book is a great find for highly trained scholars in the field of receptor research, including biochemists, chemists, pathologists, morphologists, physiologists, and pharmacologists.

  • Marine Shrimp Culture

    Principles and Practices
    • 1st Edition
    • Volume 23
    • A.W. Fast + 1 more
    • English
    The commercial culture of marine shrimp in tropical areas has grown at a phenomenal rate during the last 10 to 15 years. This book provides a description of principles and practices of shrimp culture at one point in time and documents both historical events and conditions now. It also tries to look into the future. The volume provides both practical information about shrimp culture, as well as basic information on shrimp biology. It should be of value to researchers, consultant practitioners and potential investors in the marine shrimp culture industry.

  • The Anatomy of Aging in Man and Animals

    • 1st Edition
    • Warren Andrew
    • English
    The Anatomy of Aging in Man & Animals presents a critical review of the characteristics of invertebrates. It discusses the physical features and parts of fishes, amphibians, reptiles, and birds. It also addresses the characteristics and physiology of mammals as well as the organization of the nervous system. Some of the topics covered in the book are the descriptions and species of protozoa; description of porifera, coelenterate, and kinds of rotifer; parts and functions of mollusca; description and reproduction of annelida; types of crustacea; studies on drosophila; analysis of nutrition, temperature, and aging; and development of the nervous system of a bee. The structures of flatworms and the development of roundworms and echinodermata are discussed. An in-depth analysis of the classes of echinoidea is provided. The characteristics of thymus in an adult amphibian are also presented. A chapter is devoted to the description of changing appearance of human skin. The book can provide useful information to scientists, biologists, students, and researchers.

  • Fats in Animal Nutrition

    • 1st Edition
    • J. Wiseman
    • English
    Fats in Animal Nutrition provides a useful text containing information from many diverse disciplines that discuss the nutritional utilization of lipids of domesticated animals. The book is divided into seven parts. Part I covers the chemistry and biochemistry of animal and plant fats and their nutritional importance; Part II discusses the general principles involved in the transport and absorption of fats and how this process is facilitated in ruminant and non-ruminant animals. The book also deals with the role of essential fats in the nutrition of different animals, as well as the protective functions of fat-soluble vitamins . Part IV discusses the use of fats as an energy source for animals; Part V deals with the inclusion of fats in animal feeds and their uses. The deposition of fat in different meats and the practical applications of fat utilization in animals are covered as well. The text is recommended for agriculturists, veterinarians, and zoologists who would like to know more about the importance of the inclusion of fats in animal diets.

  • Structure-Function Properties of Food Proteins

    • 1st Edition
    • Lance G. Phillips
    • Steve L Taylor
    • English
    The functional properties of food proteins affect behavior in food systems and influence the quality attributes, structure, texture, mouth-feel, and flavor of the final product. These attributes are precisely those with which food engineers and technologists are concerned when developing new products. This innovative book provides an overview of the physical properties of proteins and how dynamic changes in conformation, structural changes, and protein-protein interactions are involved in the performance of particular functional properties such as gelation, emulsification, and foaming properties. Models used include B-Lactoglobulin, soy, and meat proteins.

  • Fundamentals of Radiobiology

    International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences
    • 2nd Edition
    • Z. M. Bacq + 1 more
    • English
    Fundamentals of Radiobiology presents a clear picture of the effects of radiation to living organisms. It discusses the steps leading from the absorption of energy to death or final injury. The focus of study is the changes induced at the molecular level by absorbing energy. Some of the topics covered in the book are the methods for determining the direct and indirect action in biological systems, the nature of the initial chemical lesion in cellular radiobiology, the definition of target theory and the meaning of poison theory. The subjects on general radiation chemistry are also covered. The fields of radiation chemistry that will be discussed are the role of excitation, the variation of reactions between gases, liquids, and solids; and the status of free radicals created. The effects of radiation on macromolecules are discussed. The text defines the important role of metabolism in the development of the lesions. An analysis of the interactions of ionizing radiations with is presented. A chapter of the volume is devoted to the radiation chemistry of aqueous systems. Another section of the book focuses on the chemicals which simulate the biological effects of ionizing radiations. The book will provide useful information to doctors, chemists, biologists, radiologists, students and researchers.

  • Development of Anti-Asthma Drugs

    • 1st Edition
    • Derek R. Buckle + 1 more
    • English
    Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the disease and, therefore, in the design of better drugs. It is planned based on the concept of the causes and treatment of asthma, This book is organized in three main parts. Part I deals with the nature of asthma, its pathological mechanisms, natural history and epidemiology. Part II discusses mediators associated with asthma including platelet-activating factor, leukotrienes and histamine. Part II covers pharmaceutical approaches in the development of anti-asthma drugs and includes sections on inhibitors of mediator release and competitive and functional antagonists. This book will be of interest to persons dealing with studies on anti-asthma drugs and those interested in pharmacological development.

  • Special Methods

    Physical Techniques in Biological Research
    • 1st Edition
    • William L. Nastuk
    • English
    Physical Techniques in Biological Research, Volume IV: Special Methods presents the methods of determining body fluid volume. This book is composed of six chapters that discuss the techniques of vascular perfusion and evaluate the nature of the electrode reaction. It also demonstrates the certain characteristics of the oxygen cathode. Some of the topics covered in the book are the methods for pressure measurement; techniques in gas volume measurement; modes of gas flow measurement; applications of pressure, volume, and flow measurements; and procedures for gas analysis. Other chapters deal with the contents of perfusion media, the determination of extracellular fluid volume, and an analysis of the components of perfusion apparatus. Applications of ultrasonic fields to the study and alterations of biological systems are presented. The last chapter is devoted to the developments made in the use of flame photometry and its description. The book can provide useful information to doctors, students, and researchers.

  • Contributions to Contemporary Neurology

    A Tribute to Joseph Michael Foley
    • 1st Edition
    • Robert B. Daroff + 1 more
    • English
    Contributions to Contemporary Neurology features articles presented at the scientific meeting at the March 1986 gala evening affair held in Cleveland, Ohio in honor of neurologist Joseph Michael Foley's seventieth birthday and his impending transition to Professor Emeritus at Case Western University. This book is organized into 20 chapters written by 41 contributors. It starts with the biography of Foley and ends with his curriculum vitae. In between the biographies and curriculum vitae are basic and clinical articles written by professionals closely associated with Foley throughout his illustrious career. This book will be of interest to those interested in learning about the life and career of neurologist Joseph Michael Foley.

  • Neurosciences Research

    Volume 4
    • 1st Edition
    • S Ehrenpreis + 1 more
    • English
    Neuroscience Research, Volume 4 covers papers on a varied group of studies, ranging from synaptic transmission and local anesthetic action to the immobility reflex ("animal hypnosis") and control of food intake. The book presents papers on the mechanisms of synaptic transmission; the acetylcholine system and neural development; and the site of action and active form of local anesthetics. The text also includes papers on biological rhythms and their control in neurobehavioral perspective; neurophysiologic studies of the immobility reflex ("animal hypnosis" and the hepatic receptors and the neurophysiological mechanisms controlling feeding behavior. Neuroscientists, physiologists, and psychiatrists will find the book useful.

  • Dictionary of Nutrition and Food Technology

    • 4th Edition
    • Arnold E. Bender
    • English
    Dictionary of Nutrition and Food Technology, Fourth Edition provides definitions of terms, abbreviations, and trade names related to nutrition and food technology. The coverage of the book includes words from various scientific disciplines, such as chemistry, biochemistry, microbiology, and engineering. The text will be of great use to specialists from different fields who seek to understand the technical terms used in the food fields.

  • The Origin Nature and Evolution of Protoplasmic Individuals and Their Associations

    Protoplasmic Action and Experience
    • 1st Edition
    • Faustino Cordon
    • English
    The Origin, Nature and Evolution of Protoplasmic Individuals and their Associations explores living beings of all levels of complexity in relation to each other and to the various ambient sources that they use to survive: protoplasmic individuals and their associations, cells and their associations, animals, and man. The book considers the concepts of evolution and of living beings; the main stages in biological evolution; the organisms' individuality, nature, way of formation, phylogenetic, and ontogenetic origin; essential property of the organisms of living beings; and creature modeling. The text also discusses the phylogenesis, ontogenesis, and the nature of the soma; the spatial and temporal environment connecting biological and geological evolution; and concepts of feeding and nutrition. Three separate sections describe phylogenetic origin of the first protoplasmic individuals; the protoplasmic individual as defined by its action and experience; and evolution in protoplasmic level.

  • Essays in Toxicology

    Volume 4
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 4 covers three essays on habituating drugs, on the kinetics of the active-site-directed irreversible inhibition, and the hidden effects of trace elements. The first essay examines certain dependence-producing drugs; the mechanism of tolerance to barbiturates by changes in drugs metabolism; the distribution of barbiturates to the central nervous system; and the urinary excretion of barbiturates. The formation of morphine from heroin and codeine, and the dealkylation to form normorphine and to reduce naloxone to another compound is also considered in the first essay. The second essay discusses the time-course of enzyme inhibition at single-inhibitor concentrations and the effect of various inhibitor concentrations on the rate constants governing inhibition. The third essay is about the recondite toxicity of trace elements, taking into consideration the effects of these trace elements on body weight, survival, and longevity, clues to mechanisms of toxicity, and the production of chronic diseases simulating human disorders. Toxicologists, oncologists, biochemists, and pharmacologists will find the book invaluable.

  • Wheat Studies - Retrospect and Prospects

    • 1st Edition
    • Volume 3
    • H. Kihara
    • English
    This authoritative work has been written by a man whose career as an active wheat geneticist has spanned sixty years and has earned him a world-wide reputation. The book contains descriptions and much original data on genetical and cytogenetical findings concerning cultivated wheats and their relatives. It covers chromosomal analyses, genome analyses, ancestors of wheat, artificial synthesis of wheat, evidence of cytoplasmic inheritance and variations of wild species. The author explains how these facts and concepts have been discovered, points out the importance inherent in these discoveries, and shows how they can be utilized in genetical and breeding studies. Special emphasis is placed on the motives, processes and development of the studies.

  • Charles Darwin

    The Founder of the Theory of Evolution and Natural Selection
    • 1st Edition
    • Gerhard Wichler
    • English
    Charles Darwin: The Founder of the Theory of Evolution and Natural Selection provides a comprehensive coverage of the whole spectrum of the theory of evolution. The title presents the historical accounts and conceptual basis that leads to the foundation of the theory of evolution. The text first covers the history of the theory of evolution; the book also details the early form of the theory up to the point of the theories acceptance. Next, the selection discusses the basis and development of theory of evolution. The book will be of great interest to anyone who wants to investigate in great depth the theory of evolution.

  • Low Blood Pressure

    Its Causes and Significance
    • 1st Edition
    • J. F. Halls Dally
    • English
    Low Blood Pressure: Its Causes and Significance focuses on the important and interesting aspects of low arterial pressure. This book discusses the vasomotor control of arterial pressure; significance of low arterial pressure; autonomic-endocrine influences; and symptomatology of acquired hypopiesis. The parasympathetic or extended vagus system; arteriosclerosis of large vessels; psychical low arterial pressure; and agents causing vascular dilatation are also deliberated. This text likewise covers the exanthematous infections of doubtful etiology; atrophic cirrhosis of the liver; occasional difficulties in diagnosis; and control of low arterial pressure. This publication is intended for medical practitioners and clinicians aiming to acquire knowledge of low arterial pressure and its associations.

  • Research in Protozoology

    In Four Volumes
    • 1st Edition
    • Tze-Tuan Chen
    • English
    Research in Protozoology is the third book in a four-volume series on protozoological research. Like the previous two, this volume covers the cytology, parasitology, fibrillar systems, and genetics of protozoans. This volume explores the immunological aspects of infections caused by protozoans, identifies the organisms that live in and on protozoans, and describes the pathogenic and metabolic pathway of protozon infections. It also discusses the protozoan fibrillar system and the macronucleus of ciliates. This book will be of interest to persons dealing with studies on the genetics aspects, cytology and parasitology of protozoans.

  • Human Afflictions and Chromosomal Aberrations

    International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences
    • 1st Edition
    • Raymond Turpin + 1 more
    • P. Alexander + 1 more
    • English
    Modern Trends in Physiological Sciences, Volume 32: Human Afflictions and Chromosomal Aberrations presents the study of the links between chromosome aberrations and physical and mental congenital anomalies. This book discusses the possibilities of human cytogenetic research as well as its difficulties. Organized into 15 chapters, this volume begins with an overview of the development of human chromosome investigations. This text then explains the methods for studying human chromosomes, which can be applied without controlling the atmosphere of the incubator. Other chapters describe the structural features of the normal human karyotype. This book discusses as well the early appearance of a chromosome aberration that produces a change in the hereditary patrimony manifest in a constitutional disorder of the individual. The final chapter deals with the biochemical effects that correspond to numerical or structural anomalies in chromosome 21. This book is a valuable resource for genetecists, cytogeneticists, physicians, and clinical researchers.

  • Hormones and Embryonic Development

    Advances in the Biosciences
    • 1st Edition
    • G. Raspé
    • English
    Advances in the Biosciences 13: Hormones and Embryonic Development investigates various aspects of hormones and embryonic development, including their physiological and pharmacological effects. More specifically, this volume considers which maternal hormones are essential for normal mammalian embryonic development, as well as the time course of the occurrence of endocrine systems during mammalian fetal development. In addition, it examines the role of maternal or fetal hormones in the induction and differentiation processes during embryonic or fetal development. Comprised of 13 chapters, this book begins with an analysis of the metabolic effects of insulin and glucagon in fetal and newborn rats, as well as their physiologic significance during the perinatal period in rat and other species. The next chapter deals with sexual differentiation in the rat fetus; how hormones regulate sexual development and disrupt sexual differentiation; the role of progesterone and estrone in pregnant rats fed a protein-free diet; and effects of brain implants of testosterone propionate in newborn hamsters on sexual differentiation. The link between diethylstilbestrol ingestion during pregnancy and development of clear-cell adenocarcinoma in the vagina and cervix of the female offspring is also examined. This monograph will be of interest to biologists, bioscientists, physiologists, and pharmacologists.

  • The Brain as a Computer

    International Series of Monographs on Pure and Applied Biology: Zoology
    • 1st Edition
    • F. H. George
    • G. A. Kerkut
    • English
    The Brain as a Computer, Second Edition is a 14-chapter book that outlines the principles of cybernetics in relation to behavior, from the perspective of experimental psychology and neurophysiology. This book begins by describing the main ideas of cybernetics. Subsequent chapters explore cybernetic models, with emphasis on finite automata, and particularly finite automata in logical net form, which seem especially useful to the modeling of behavior. Other chapters summarize learning theory, neurological matters, thinking, perception, and artificial intelligence.

  • Irrigation and Agricultural Development

    Based on an International Expert Consultation, Baghdad, Iraq, 24 February - 1 March 1979
    • 1st Edition
    • S. S. Johl
    • English
    Irrigation and Agricultural Development compiles selected papers presented at the International Expert Consultation held in Baghdad, Iraq from February 24 to March 1, 1979. This book addresses the technical, economic, and institutional problems connected with the development and utilization of irrigation water for agricultural production. It discusses the policy framework for investment in irrigation projects; natural equilibriums and irrigated agriculture; and selection of appropriate irrigation methods for semi-arid regions. The studies on crop consumptive use of water in Iraq; world bank experience with irrigation, drainage and land reclamation projects; and salinity problems and land reclamation in the Arab Republic of Egypt are also covered. This publication is recommended for environmentalists, irrigation engineers, and agriculturists concerned with water development, conservation, and management.

  • Selected Water Problems in Islands and Coastal Areas

    With Special Regard to Desalination and Groundwater
    • 1st Edition
    • Sam Stuart
    • English
    Selected Water Problems in Islands and Coastal Areas serves as a guideline for implementing, at the policy and decision-making level, the rational and economic use of water resources. This book focuses on groundwater management and the possible utilization of desalination facilities, specifically in arid or semi-arid coastal areas. Organized into five parts encompassing 63 chapters, this book begins with an overview of the forecasts of water supply requirements. This text then explores the necessary regulations of both surface and groundwater in coastal areas and islands with limited water resources. Other chapters consider the curative measures in the case of recurring salination by using artificial or increased natural infiltration. This book discusses as well the techniques to be used for artificial infiltration into aquifers using deep wells to avoid clogging. The final chapter deals with the problems of communal installations, water supply, drainage and waste disposal. This book is a valuable resource for engineers.

  • Environmental Soil Chemistry

    • 1st Edition
    • Donald L. Sparks
    • English
    As the author states in his Preface, this book is written at a time when scientific and lay communities recognize that knowledge of environmental chemistry is fundamental in understanding and predicting the fate of pollutants in soils and waters, and in making sound decisions about remediation of contaminated soils. Environmental Soil Chemistry presents the fundamental concepts of soil science and applies them to environmentally significant reactions in soil. Clearly and concisely written for undergraduate and beginning graduate students of soil science, the book is likewise accessible to all students and professionals of environmental engineering and science. Chapters cover background information useful to students new to the discipline, including the chemistry of inorganic and organic soil components, soilacidity and salinity, and ion exchange and redox phenomena. However, discussion also extends to sorption/desorption, oxidation-reduction of metals and organic chemicals, rates of pollutant reactions as well as technologies for remediating contaminated soils. Supplementary reading lists, sample problems, and extensive tables and figures make this textbook accessible to readers.

  • Recent Advances in Animal Nutrition

    • 1st Edition
    • W. Haresign
    • D.J.A. Cole + 2 more
    • English
    Recent Advances in Animal Nutrition-1981 is a collection of papers that discusses the effects of dietary fat on milk composition, relating it to the biochemistry of fat synthesis in the mammary gland. The influence of concentrates on milk composition as well as the pattern and level of concentrate feeding on milk output are also covered. The book describes the need for better utilization of grass and grass products in dairy production, the mineral and trace element requirements of pigs; the importance of anion-cation balance in poultry diets and its effects on performance levels; and the selenium and cobalt requirements of ruminants. The problems of medicinal residues in animal products and the toxicological effects of aflatoxin residues in animal products are also considered. People involved in agriculture, dairy production and animal nutrition will find the book useful.

  • A Synopsis of Respiratory Diseases

    • 1st Edition
    • J. Smart
    • English
    A Synopsis of Respiratory Diseases discusses the concept of pulmonary physiology and its diseases. This book is composed of 10 chapters that address the development and treatment of tuberculosis. Some of the topics covered in the book are the essential function of the lungs; transfer of gases; blood gas analysis; definition of acute respiratory failure; different diseases of the nose; ailments of the larynx; conditions of spasm or obstruction of the larynx; types of ventilators; control of respiration; and differential lung function. Other chapters describe the physiological instances leading to carbon dioxide narcosis and some diseases of the trachea. The discussion then shifts to the etiology, histology, and bacteriology of chronic bronchitis. The concluding chapters are devoted to the definition and treatment of emphysema, as well as the diagnosis of tumors of the bronchus. The book can provide useful information to doctors, students, and researchers.

  • Neural Modeling and Neural Networks

    • 1st Edition
    • F. Ventriglia
    • English
    Research in neural modeling and neural networks has escalated dramatically in the last decade, acquiring along the way terms and concepts, such as learning, memory, perception, recognition, which are the basis of neuropsychology. Nevertheless, for many, neural modeling remains controversial in its purported ability to describe brain activity. The difficulties in "modeling" are various, but arise principally in identifying those elements that are fundamental for the expression (and description) of superior neural activity. This is complicated by our incomplete knowledge of neural structures and functions, at the cellular and population levels. The first step towards enhanced appreciation of the value of neural modeling and neural networks is to be aware of what has been achieved in this multidisciplinary field of research. This book sets out to create such awareness. Leading experts develop in twelve chapters the key topics of neural structures and functions, dynamics of single neurons, oscillations in groups of neurons, randomness and chaos in neural activity, (statistical) dynamics of neural networks, learning, memory and pattern recognition.

  • Neural Models of Plasticity

    Experimental and Theoretical Approaches
    • 1st Edition
    • John H. Byrne + 1 more
    • English
    Neural Models of Plasticity: Experimental and Theoretical Approaches is an outgrowth of a conference that was held at Woods Hole, Massachusetts, in the spring of 1987. The purpose of that conference was to review recent developments in both areas and to foster communication between those researchers pursuing theoretical approaches and those pursuing more empirical approaches. Contributions have been solicited from individuals who represent both ends of the spectrum of approaches as well as those using a combination of the two. These indicate that our knowledge of the plastic capabilities of the nervous system is accelerating rapidly due to rapid advances in the understanding of basic subcellular and molecular mechanisms of plasticity, and because of the computational capabilities and plastic properties that emerge from neural networks and assemblies. The book contains 19 chapters and opens with a study on the role of the neuromodulator in associative learning of the marine mollusk Hermissend. Subsequent chapters examine topics such as learning and memory in Aplysia; the Hebb rule for synaptic plasticity; olfactory processing and associative memory in the mollusk Limax maximus; simulation of a classically conditioned response; and the neural substrates of memory, focusing on the role of the hippocampus.

  • Feed Energy Sources for Livestock

    • 1st Edition
    • Henry Swan + 1 more
    • English
    Feed Energy Sources for Livestock focuses on the compositions of animal feeds. The book first looks at the background of world grain supplies from 1972 to 1974 and 1975 onwards. The text discusses alternatives to conventional cereals. Fats in ruminants, pigs, and poultry diets; chemically treated straw; and less conventional raw materials are described. The book also looks at molasses and its by-products, processing of cereals, and the effects of an alkali technique on the nutritive value of straws. The text discusses as well the laboratory methods used in evaluating the energy value of feedstuffs. Neutral detergent fiber; in vitro rumen digestibility; Tilley and Terry in vitro rumen method; in vitro true digestibility; and modified acid detergent fiber are considered. The book then focuses on the sources, availability, and use of additional phosphorous for ruminants; selenium and Vitamin E in poultry rations; and the use of rapeseed meal in pig and poultry rations. The selection is a valuable source of information for readers wanting to study the contents of animal feeds.

  • Drugs in Psychiatric Practice

    • 1st Edition
    • Sam Stuart
    • English
    Drugs in Psychiatric Practice present a comprehensive examination of the drug treatment in psychiatry. It discusses certain ways in which drugs behaved. It addresses the advances in pharmacology and the basis of prescription. Some of the topics covered in the book are the classification of psychotropic drugs; basic principles of pharmacokinetics and drug metabolism; anti-schizophrenic drugs; evaluation of psychotropic drugs; unconventional chemotherapy; anti-parkinsonian and anti-dyskinetic drugs; introduction of amitriptyline; and tricyclic antidepressants. The role of tricyclic drugs in the treatment of enuresis and the drug treatment of organic brain syndrome are fully covered. An in-depth account of the monoamine oxidase inhibitors and amine precursors are provided. The tolerance and pharmacological dependence on alcohol are completely presented. A chapter is devoted to the factors involve in ethanol metabolism. Another section focuses on the unwanted effects of psychotropic drugs. The book can provide useful information to doctors, pharmacists, psychologists, students, and researchers.

  • Comparative Experiments with Field Crops

    • 1st Edition
    • G.V. Dyke
    • English
    Comparative Experiments with Field Crops is a guide on how to organize comparative experiments about field crops. The book is divided into two parts. Part I deals with how to do and interpret field experiments; the planning of field experiments and special considerations to take into mind; the marking out, sowing, counting, and scoring of field crops; and the harvest as well as sampling. Part II covers the statistics involved in field experiments, and include comparisons and degrees of freedom and error; multidimensional geometry; regression analysis; and analysis of covariance. The text is recommended for agriculturists and botanists who intend to make a comparative study on field crops and are in need of a reference.

  • Trophic Regulation of the Basal Ganglia

    Focus on Dopamine Neurons
    • 1st Edition
    • K. Fuxe + 2 more
    • English
    Trophic Regulation of the Basal Ganglia: Focus on Dopamine Neurons examines neurotransmitters. The book first discusses the role of fibroblast growth factor-2 (FGF-2) and ganglioside GM1 and the trophic regulation of the basal ganglia. Biochemical and histochemical studies on the cellular localization of FGF-2; mapping of FGF-2 and its receptors in the basal ganglia postnatally and adulthood; and mapping of the ganglioside GM1 distribution in the basal ganglia are presented. The text also explains glucocorticoid and estrogen effects on the nigrostriatal and mesolimbic dopaminergic systems; factors associated to dopaminergic cell death in Parkinson's disease; and compensatory mechanisms at dopamine D-2 receptors. The book also describes the effects of brain-derived neurotrophic factor on injured dopaminergic neurons; role of gangliosides and trophic factors in brain repair; and features of the trophic action of polyamines. The text also underscores the presence of interleukin-1 in the central nervous system; neuropeptides synthesis in astrocytes; and astrocytic kynurenines as modulators of dopaminergic function in the rat basal ganglia. The selection is a good source of information for readers wanting to study neurotransmitters.

  • Experimental Analysis of Behavior

    • 1st Edition
    • Volume 6
    • I.H. Iversen + 1 more
    • English
    This volume is dedicated to the late B.F. Skinner as a tribute to his pioneering work on the Experimental Analysis of Behavior. This science that he initiated studies the behavior of individual organisms under laboratory conditions.The volume describes a broad collection of representative and effective research techniques in the Experimental Analysis of Behavior; techniques derived solely from infrahuman subjects, which have been selected both for their utility in behavior analysis and for their potential value in expanding the use of behavior analysis in the neurosciences. By bringing together under one cover the expertise of individual authors regarding techniques based on their particular laboratory experiences, the book provides an informative and practical source of methods and techniques for those practising or interested in Experimental Analysis of Behaviour.

  • Genetics of the Norway Rat

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • Roy Robinson
    • G. A. Kerkut
    • English
    Genetics of the Norway Rat details the various genetic traits of Norway rat. The book covers a wide spectrum of trait inheritance, from color variation up to the various genetic mutation and quirks. The coverage of the text includes growth, metabolism, reproduction, and endocrinology. Several chapters also cover the physiological traits that include skeleton, viscera, sensory organs, and nervous. The text also takes into consideration the immunogenetics, pharmacogenetics, psychogenetics, and cytogenetics of the species studied. The book will be of great interest to mammalian geneticists. Researchers who are using rats as a test subject in their research will also benefit from the text.

  • Perspectives in Zoology

    International Series of Monographs in Pure and Applied Biology Zoology Division
    • 1st Edition
    • Alan Boyden
    • English
    Perspectives in Zoology tries to discuss in a critical way some of the aspects of biology that lack perspective. The book also calls into attention the possibilities of obtaining a more correct view and challenges views that already have already been accepted by the scientific community. In this thought-provoking book, many questions are raised and different viewpoints and their implications are considered in the areas of natural history. Coverage includes the great ages of evolution; the primitive evolution in the eumatozoa; the morphological comparisons between homology and analogy; systematic serology and its principles; and the relationship of systemics, evolution, and phylogeny. The text is recommended for students and professors that deal with biology, zoology, genetics, and evolution who not only wish to explore and understand other approaches to popular theories in zoology, but also wish to be more familiarized and delve deeper with the common yet frequently discussed and debated topics in the field.

  • Pharmaceutical and Biomedical Applications of Liquid Chromatography

    • 1st Edition
    • Volume 1
    • W.J. Lough + 2 more
    • English
    This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

  • Plant Proteins

    Easter School in Agricultural Science
    • 1st Edition
    • G. Norton
    • English
    Plant Proteins is a compendium of papers discussing, in general, plant proteins as materials for human foods, and in particular, the properties, biosynthesis, deposition of reserves in seeds, undesirable factors, production, and nutritional aspects of plant proteins in the food industry. Some papers review the properties and biosynthesis of plant proteins, the synthesis of chloroplast proteins, and legume seed proteins. Other papers discuss the development of protein reserves in seeds, as well as the toxicity and antagonistic actions in relation to amino acid and protein synthesis. One paper examines the world supply and demand for sources of protein from three plant sources, namely cereals, oilseeds, and legumes. Another paper discusses the capabilities of certain species of micro-organisms to synthesize from a few simple raw materials all the main components needed in the diet of a human or a farm animal. One paper notes that the acceptance of plant protein foods in society depends on their presentation, flavor, texture, appearance, identity, and product name. This compendium will benefit agronomists, agriculturists, biochemists, microbiologists, nutritionists, botanists, chemists, economists, food scientists, physicists and plant breeders.

  • Catalytic RNA

    • 1st Edition
    • Volume 120
    • English
    This special volume of Progress in Molecular Biology and Translational Science focuses on catalytic RNA. Written by experts in the field, the reviews cover a range of topics, from hammerhead ribozymes to spliceosome catalysis to Varkud satellite and hairpin ribozymes.

  • Pharma's Prescription

    How the Right Technology Can Save the Pharmaceutical Business
    • 1st Edition
    • Kamal Biswas
    • English
    The pharmaceutical industry needs a shot in the arm – and not a moment too soon. The executive suite is mired in a bygone era, a time when extensive, well-funded pharmaceutical R&D produced blockbuster drugs, kept everything in-house and reaped the financial rewards. But that way of working needs to change. Executives now need to know what the technologists in their companies are doing in order to survive the next decade. Written for those new to industry, as well as for experienced professionals or specialists looking to expand their knowledge, this book is a must-read for business executives and information technologists alike. Pharma’s Prescription bridges the knowledge gap between current business practices and the most valuable technologies today. This book is filled with practical, real-life examples from industry and is a straightforward guide for all pharmaceutical and information technology executives who need to improve their businesses.

  • Biomaterials for Cancer Therapeutics

    Diagnosis, Prevention and Therapy
    • 1st Edition
    • Kinam Park
    • English
    Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.

  • Receptor-Receptor Interactions

    • 1st Edition
    • Volume 117
    • P. Michael Conn
    • English
    This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.

  • From Academia to Entrepreneur

    Lessons from the Real World
    • 1st Edition
    • Eugene Khor
    • English
    From Academia to Entrepreneur: Lessons from the Real World provides practical advice on entrepreneurship, interspersed with insights the author gained from starting up his own business and in associations with other ventures. These same insights can be applied to bringing a technology concept from academia to an enterprise. A few of the questions From Academia to Entrepreneur: Lessons from the Real World answers: How do I pragmatically appraise business opportunities? What traits should I look for in an enterprise? What can and should I do with my concept while in academia, before entering such an endeavor? How do I overcome risk aversion? And most importantly, why should I be the one to build this business?

  • Principles of Tissue Engineering

    • 4th Edition
    • Robert Lanza + 2 more
    • English
    Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.

  • Quest for the Cure

    Reflections on the Evolution of Breast Cancer Treatment
    • 1st Edition
    • George R. Blumenschein
    • English
    This original fourteen chapter book is a brief, slightly autobiographic tale of medical oncologists, surgeons, radiation oncologists, and breast cancer patients in a well-established cancer center in Texas, who pursued the goal of cure for breast cancer. The evolution of improved outcomes in the treatment of microscopic metastatic breast cancer is also the story of the development of adjuvant chemotherapy for post-operative breast disease. The adjuvant therapy of breast cancer came about with the realization that this malignancy, when diagnosed in most patients, had spread beyond the confines of the primary cancer.

  • The HDL Handbook

    Biological Functions and Clinical Implications
    • 2nd Edition
    • Tsugikazu Komoda
    • English
    The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

  • Membrane Research: Classic Origins and Current Concepts

    • 1st Edition
    • A. L. Muggleton-Harris
    • English
    Membrane Research: Classic Origins and Current Concepts is a special volume of the International Review of Cytology dedicated to Dr. Danielli on the occasion of his retirement from official duties. The central theme of the volume is membranes. The diversity of topics ranges from the biogenesis of membranes and their components, to the use of optical and lectin probes as a means to study the structure, physiology, and interactions of cell components and organelles in plant and animal systems. The book begins with a study on the cell surface of the mammalian embryo and the events associated with the formation of the differentiated blastocyst. This is followed by separate chapters on the structural associations between the inner and outer bacterial membrane; the interactions of cell wall and membrane in plant cells; the morphological and functional aspects of membranes; and methods for studying the physiology of cell and organelles at the membrane level. Subsequent chapters deal with the synthesis of cellular proteins and glycoproteins; techniques for fixing and preserving the ultrastructure of the membrane; the synthesis of artificial organelles; and the effects of drugs and chemicals on membrane transport utilizing kidney tissue and vesicles. This book provides an outstanding reference source for all scientific researchers and teachers.

  • De Indiae utriusque re naturali et medica libri quatuordecim

    • 1st Edition
    • Willem Piso
    • English

  • Biology of the Rhizobiaceae

    International Review of Cytology, Vol. 13
    • 1st Edition
    • Kenneth L. Giles + 1 more
    • English
    Biology of the Rhizobiaceae covers the genetics, molecular biology, agricultural, and morphological aspects of the rhizobia. The book discusses the taxonomy and identification of the Rhizobiaceae; the biology of Agrobacterium tumefaciens and the specific events in the disease cycle of crown gall; and the agricultural control of Agrobacterium tumefaciens. The text also describes the growth potential of crown gall tumors and crown gall teratoma; plasmid studies in crown gall tumorigenesis; and the biology and microbiology of Agrobacterium rhizogenes. The recognition in rhizobium-legume symbioses; the rhizobium bacteroid state; and the exchange of metabolites and energy between legume and rhizobium are also considered. The book further tackles the mutants of rhizobium that are altered in legume interaction and nitrogen fixation; as well as the significance and application of Rhizobium in agriculture. Botanists, agriculturists, geneticists, molecular biologists, microbiologists, plant pathologists, and agronomists will find the book invaluable.

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