Advances in Clinical Chemistry
- 1st Edition, Volume 59 - December 31, 2012
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- eBook ISBN:9 7 8 - 0 - 1 2 - 4 0 5 8 5 2 - 1
Volume 59 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors a… Read more
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Request a sales quoteVolume 59 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
- Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology
Biochemists and clinical biochemists
Contributors
Preface
Chapter One. Human Epididymis Protein 4 in Cancer Diagnostics
1 Introduction
2 General Characteristics (Fig. 1.1)
3 Analytical Methods
4 Cancer Diagnostics (Table 1.1)
5 Discussion
References
Chapter Two. Pathophysiological Roles and Clinical Importance of Biomarkers in Acute Coronary Syndrome
1 Introduction
2 Pathogenesis Underlying Myocardial Ischemia/Infarction
3 Ideal Cardiac Biomarkers
4 History of Cardiac Biomarkers
5 Myocardial Dysfunction
6 Myocardial Necrosis
7 Myocardial Ischemia
8 Biomarkers of Inflammation
9 Perspectives and Future Strategies
10 Conclusion
References
Chapter Three. Paraoxonases
1 Historical Overview: From Toxicology to Cardiovascular Disease
2 The PON Enzyme Family
3 PON as Multitasking Enzymes: Pathways Related to Atherosclerosis
4 PON and Ischemic Heart Disease: Animal Studies
5 PON and Ischemic Heart Disease: Epidemiologic and Clinical Studies
6 PON1 as a Potential Therapeutic Tool
7 Concluding Remarks
References
Chapter Four. Mucosal Healing in Ulcerative Colitis
1 Introduction
2 Molecular Pathways of Intestinal Mucosal Wounding in Ulcerative Colitis
3 Epithelial Healing in Ulcerative Colitis Has an Impact on Disease Course
4 The Pharmacodynamics of Wound Healing
5 Conclusions
References
Chapter Five. Reticulocytes in Sports Medicine
1 Introduction
2 Preanalytical Phase
3 Kinetics of Ret Production in Humans
4 Reported Ret Values in Athletes
5 Stability
6 Comparison of Ret Values Between Athletes and Sedentary People
7 Effects of Exercise on Ret
8 Doping
9 Conclusions
References
Chapter Six. Toll-Like Receptors in Liver Disease
1 Introduction
2 The Role of Toll-Like Receptors in Innate Immunity
3 Expression of Toll-Like Receptors in the Liver
4 Toll-Like Receptors in the Pathogenesis of Liver Diseases
5 The Role of TLR in the Pathogenesis of Long-Term Consequences of ALD and NASH
6 TLR Signaling as Target for Therapy of ALD and NASH
7 Synergy Between Alcohol Consumption and NAFLD
8 Conclusions
References
Chapter Seven. Procalcitonin in Pediatrics
Abbreviations
1 Introduction
2 PCT and the Newborn
3 PCT and the Ill Infant and Child
4 Conclusions
References
Index
- Edition: 1
- Volume: 59
- Published: December 31, 2012
- Imprint: Academic Press
- No. of pages: 288
- Language: English
- eBook ISBN: 9780124058521
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USARead Advances in Clinical Chemistry on ScienceDirect