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Elsevier

Books in Life sciences

  • Emerging Sources and Applications of Alternative Proteins

    • 1st Edition
    • Volume 101
    • English
    Protein nutrition and sustainability is a global challenge. Emerging Sources and Applications of Food Proteins provides the latest progresses about research and applications of emerging alternative proteins. Topics covered in this volume include rapeseed (canola) proteins, pulse proteins, insect proteins, fungal proteins, artificial meat, and new applications in bioactive peptides, nanotechnology, 3D printing, meat alternatives, with a focus on the consumer trend and practical applications.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 109
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 109, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on Biomarkers of dysfunctional visceral fat, Immunoassay Design and Biotin Interference, Orexin/Hypocretin and Major Psychiatric Disorders and more.

  • The Paradox of the Immune System

    Protection, Chronic Inflammation, Autoimmune Disease, Cancer, and Pandemics
    • 1st Edition
    • Louis J. Catania
    • English
    The Paradox of the Immune System: Protection, Inflammation, Autoimmune Disease and Beyond provides a provocative approach to immunology as a "double-edged sword." While it is our greatest protector, it is also the cause of chronic inflammation that leads to autoimmune disease, cancer and infectious diseases like COVID-19. Sections cover the basic science of immunology and its intimate genetic associations, biomedical hypotheses asserting immunology as the basis of all human diseases, and elaborate on immunology as "the enemy within us." This engaging, original approach to a science so personal provides new and invaluable understanding on the bioscience that controls our lives.

  • Promoting Responsive Feeding During Breastfeeding, Bottle-Feeding, and the Introduction to Solid Foods

    • 1st Edition
    • Alison Ventura
    • English
    Promoting Responsive Feeding During Breastfeeding, Bottle-Feeding, and the Introduction to Solid Foods　addresses how caregiver feeding practices and styles shape the quality and outcome of feeding interactions during infancy. Emphasis is placed on　how　the quality and nature of caregiver-child interactions during breastfeeding, bottle-feeding,　and the introduction to solid foods　shape the development of children’s eating behaviors, growth trajectories and chronic disease risk. The book also considers the potential influence of broader contextual factors on early feeding interactions, including how psychological, social, cultural and economic factors may influence caregivers’ abilities to implement feeding recommendations.

  • Diabetes Digital Health and Telehealth

    • 1st Edition
    • David C. Klonoff + 2 more
    • English
    Diabetes Digital Health and Telehealth explains, from technologic, economic and sociologic standpoints how digital health and telehealth have come to dominate the management of diabetes. The book also includes information on improved telemedicine tools and platforms for communicating with patients, reviewing medical records, and interpreting data from wearable devices. In addition, evolving wearable sensors such as continuous glucose monitors, closed loop automated insulin delivery systems, cuffless blood pressure monitors, exercise monitors and smart insulin pens are covered.

  • Integrative Strategies for Bioremediation of Environmental Contaminants, Volume 2

    Avenues to a Cleaner Society
    • 1st Edition
    • Riti Thapar Kapoor + 1 more
    • English
    Integrative Strategies for Bioremediation of Environmental Contaminants, Volume Two: Avenues to a Cleaner Society focuses on the exploitation of various biological treatment technologies and their use to treat toxic contaminants present in industrial effluent to restore contaminated sites. The book includes coverage of combined treatments of microbes for reuse of wastewater and contaminated soil to successfully achieve eco-restoration, environment protection and sustainable development. In 14 chapters, this reference compiles current and advanced biotechnologies as well as future directions for research. This is a valuable resource for researchers in microbiology, biotechnology, environmental engineering and environmental science, and all those who wish to broaden their knowledge in the field of applied microbiology to develop sustainable waste management.

  • Biocatalysis in Green Solvents

    • 1st Edition
    • Pedro Lozano
    • English
    Biocatalysis in Green Solvents offers a pragmatic overview and instruction in biocatalysis and enzymology of green solvents for sustainable industries and medicine, running from concept to application. Here, international experts in the field discuss structure-function relationships of enzymes in ionic liquids (ILs) and examine how enzymes act as selective catalysts for fine biochemical synthesis in non-aqueous environments. Several integral green biochemical processes of biocatalytic transformation and pure product separation are described in detail. Application focused chapters discuss the role of biocatalysis in creating and implementing deep eutectic solvents, biomass derived solvents, sub and supercritical fluids, carbon dioxide biphasic systems, and enzymatic membrane reactors, as well as applying these biocatalytic processes in drug discovery and production.

  • Immunopathology, Diagnosis and Treatment of HPV induced Malignancies

    • 1st Edition
    • Prashant Khare + 1 more
    • English
    Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies.

  • Krause and Mahan’s Food and the Nutrition Care Process

    • 16th Edition
    • Janice L Raymond + 1 more
    • English
    **Selected for 2026 Doody's Core Titles as an Essential Purchase in Nutrition**Provide optimal nutritional care with the latest guidelines to evidence-based practice! Krause and Mahan’s Food & the Nutrition Care Process, 16th Edition provides an all-in-one resource for the dietetics information you need to care for patients throughout the entire life cycle. With insight from clinical specialists, the book guides you through the steps of assessment, diagnosis and intervention, monitoring, and evaluation. It also covers nutrition in each stage of life, weight management, medical nutrition therapies for conditions and disorders, and the use of nutrition therapies in childhood. From a team of nutrition experts led by Janice L. Raymond and Kelly Morrow, this classic text has been trusted by nurses, nutritionists, and dieticians for since 1952.

  • Application of Sampling and Detection Methods in Agricultural Plant Biotechnology

    • 1st Edition
    • Ray Shillito + 1 more
    • English
    Application of Sampling and Detection Methods in Agricultural Plant Biotechnology describes detection methods for seed, plants and grain derived from biotechnology. This international handbook, based on a series of workshops carried out for governments in collaboration with ILSI and Co-published in partnership with the Cereals & Grains Association, provides the technical and practical information needed to develop, validate and use detection methods. This useful resource provides readers with the tools necessary to carry out reliable sampling, detection and interpretation of data.

  • Cellular Immunity in the Peritoneum

    • 1st Edition
    • Volume 371
    • English
    Adoptive Cell Transfer, Volume 371 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting interesting chapters written by an international board of authors who expound on topics such as the Impact of tumor microenvironment on Adoptive Cell Transfer activity, Dendritic Cell Transfer, CAR-T Cell dysfunction and exhaustion, NK Cell-based cancer immunotherapy, Enabling CAR-T cells for solid tumors: rage against the suppressive tumor microenvironment, Improving Adoptive T-Cell therapy with cytokines administration, and What will (and should) be improved in Immunotherapy with CAR?

  • Forest Microbiology Vol.3_Tree Diseases and Pests

    Tree Diseases and Pests
    • 1st Edition
    • Fred O Asiegbu + 1 more
    • English
    Forest Microbiology: Tree Diseases and Pests, Volume Three in the Forest Microbiology series, provides an overview of major disease agents of trees, including viruses, phytoplasma, bacteria, fungi, nematodes and major insect pests. With a strong emphasis on genetics, biochemistry, physiology, evolutionary biology and population dynamics of the organisms involved, this book provides a comprehensive understanding on the health of forests. Sections cover important pest threats such as bark beetles, emerald ash borer, coffee borers, leaf cutting ants, cocoa mirids, and more. This volume highlights a range of emerging diseases of forest trees in temperate and tropic regions as well as information on habitats. Forest trees play crucial roles not only for mitigating effects of the climate change but also for their considerable economic and ecological value. Forest trees are equally vital as an alternative bioenergy source and play important roles in pollution abatement and the maintenance of biodiversity. Timber and its associated products from forest trees contribute substantially to the revenue generation of many countries of the world.

  • Microbial Crosstalk with Immune System

    New Insights in Therapeutics
    • 1st Edition
    • Asmita Das
    • English
    Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.

  • Circadian and Visual Neuroscience

    • 1st Edition
    • Volume 273
    • English
    Circadian and Visual Neuroscience, Volume 273 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics including Optical set-ups, Psychophysics of Luminance and Color Vision, Psychophysics of non-visual photoreception PRC/IRC/DRC/Spectral Sensitivity, Circadian and visual photometry, Modelling (retina), Modelling (circadian), Techniques for examining vision at the cellular level, Advanced techniques for characterizing the world hyperspectrally, Circadian physiology in mice: Melanopsin, Circadian physiology in mice: Color and cones, Translational aspects of animal studies, Retinal clocks, Primate non-visual physiology, Light and mood in animal models, and much more.

  • Essentials of Medical Biochemistry

    With Clinical Cases
    • 3rd Edition
    • Chung Eun Ha + 1 more
    • English
    Essentials of Medical Biochemistry, Third Edition offers a condensed, yet detailed overview of clinical biochemistry, spanning fundamentals and relevant physiologic and pathophysiologic concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis. Users will find fundamental concepts aiding students and professionals in biochemistry, medicine, and other healthcare disciplines. The text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists. This Third Edition has been fully updated to address evolving techniques in the biological sciences, including genomics, metabolomics, transcriptomics, epigenomics, proteomics, and gene therapy, among other methods. In addition, each chapter has been fully revised for current science and now features learning objectives and chapter summaries, supplemental reading, and 5 clinical case based multiple choice questions. New clinical cases have been added throughout.

  • Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management

    • 1st Edition
    • Azamal Husen
    • English
    Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management highlights the latest advances in applying this important technology within agriculture sectors for sustainable growth, production and protection. The book explores various smart engineered nanomaterials which are now being used as an important tool for improving growth and productivity of crops facing abiotic stresses, improving the health of the soil in which those crops are growing, and addressing stresses once the plant begins to produce food yield. The book includes insights into the use of nanoparticles as bactericides, fungicides and nanofertilizers. In addition, the book includes an international representation of authors who have crafted chapters with clarity, reviewing up-to-date literature with lucid illustrations. It will be an important resource for researchers, nanobiotechnologists... agriculturists and horticulturists who need a comprehensive reference guide.

  • Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

    • 1st Edition
    • Sunny Ohia + 1 more
    • English
    Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-adminis... drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.

  • Neurologie de l'adolescence

    • 1st Edition
    • Agathe Roubertie + 1 more
    • French
    L’adolescence est une période unique de transformation de l’individu. Sur le plan somatique, psychique et social, le passage de l’enfance à l’âge adulte est aussi l’occasion de troubles spécifiques ou dont l’expression revêt des aspects particuliers. Ainsi, dans le domaine de la neurologie, cela se traduit par des prévalences plus élevées de certaines affections, ainsi qu’un retentissement singulier sur la personne. Les troubles neurologiques peuvent en effet compromettre les facultés essentielles à l’autonomisation de l’individu, et ont un impact sur l’image que donne l’ado à ses pairs.Sans équivalent, cet ouvrage se justifie donc par les particularités de la prise en charge, les troubles affectant les ados (adolescentes et adolescents) de façon très différente des enfants (qui s’en remettent aux adultes) et des adultes (plus autonomes et responsables dans leur prise en charge).Traitant à la fois des maladies dont les prévalences sont élevées et des affections plus rares, l’ouvrage aborde cette problématique dans toute sa spécificité, en ne négligeant aucune dimension particulière du diagnostic, du traitement et de la prise en charge globale du jeune patient. Chaque chapitre exposera successivement les spécificités à l’adolescence des données épidémiologiques et cliniques (mode de présentation, pièges diagnostiques), puis les principaux diagnostics rencontrés et proposera une prise en charge adaptée à cet âge. La question de la transition des troubles neurologiques de l’enfant à l’âge adulte et de l’accompagnement de l’ado dans sa vie scolaire et sociale sont également abordés.Cet ouvrage s’adresse aux neurologues, pédiatres et neuropédiatres, ainsi qu’aux étudiants déjà entrés dans la spécialité.POINTS CLÉS - Toutes les pathologies touchant les ados, des plus fréquentes aux plus rares - Les spécificités de la prise en charge de l’ado - L’accompagnement de l’ado et la transition vers l’âge adulte

  • Carotenoids: Carotenoid and Apocarotenoid Biosynthesis, Metabolic Engineering and Synthetic Biology

    • 1st Edition
    • Volume 671
    • English
    Carotenoids: Carotenoid and Apocarotenoid Biosynthesis, Metabolic Engineering and Synthetic Biology, Volume 671, the latest release in the Methods of Enzymology series highlights new advances in the field with chapters on Metabolomics-based analysis of carotenoids and related metabolites in various species via quantitative trait loci and genome wide association mapping approaches, Using bacteria for functional analysis of genes encoding carotenoid biosynthetic enzymes, Rice Callus as a High Throughput Platform for Synthetic Biology and Metabolic Engineering of Carotenoids, Transient expression in Nicotiana benthamiana: A simple platform to investigate genes encoding carotenoid biosynthesis enzymes from diverse algal lineages, and much more. Additional chapters in this new release cover Protein-protein interaction techniques to investigate post-translational regulation of carotenogenesis, The isolation of sub-chromoplast structures from tomato and capsicum fruit, Carrot protoplasts as a suitable method for protein subcellular localization, High throughput production and characterization of carotenoid enzymes for structural and functional studies, Production and structural characterization of the cytochrome P450 enzymes in carotene ring hydroxylation, and more.

  • Applications of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles. This volume will discuss target-specific drug application, such as ocular, transdermal, nasal, intravenous and oral delivery. This title is a valuable resource for academics, pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailored-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

  • Microbiome, Immunity, Digestive Health and Nutrition

    Epidemiology, Pathophysiology, Prevention and Treatment
    • 1st Edition
    • Debasis Bagchi + 1 more
    • English
    Microbiome, Immunity, Digestive Health and Nutrition: Epidemiology, Pathophysiology, Prevention and Treatment addresses a wide range of topics related to the role of nutrition in achieving and maintaining a healthy gut microbiome. Written by leading experts in the field, the book outlines the various foods, minerals, vitamins, dietary fibers, prebiotics, probiotics, nutritional supplements, phytochemicals and drugs that improve gut health. It specifically addresses molecular and cellular mechanisms and pathways by which these nutritional components contribute to the physiology and functionality of a healthy gut microbiome and gut health. Intended for nutrition researchers and practitioners, food experts, gastroenterologists, nurses, general practitioners, public health officials and health professionals, this book is sure to be a welcomed resource.

  • Interactions of Bone with Orthopedic Implants and Possible Failures

    • 1st Edition
    • Amirhossein Goharian + 1 more
    • English
    Interactions of Bone with Orthopedic Implants and Possible Failures focuses on the mechanical and biological issues that may cause failure of the implant-bone construct. The book provides discussions on the effects of the design, process, surface and other engineering parameters of implants and their interaction with bone tissue. For implant designers, it is highly crucial to know the final effects of what they are designing or aiming to design, along with performance parameters. It is also crucial for orthopedic surgeons to be familiar with the background of the design and process parameters of the implant they will insert in a patient’s body. With the understanding brought forth in this book, surgeons can have better implant options and implant designers can create and develop new implant designs. This book can also help biomechanical and mechanical engineers who are normally dealing with testing and analysis of orthopedic implants examine the biomechanical behavior of the implants and their interaction with bone tissue.

  • Plant Exposure to Engineered Nanoparticles

    Uptake, Transformation, Molecular and Physiological Responses
    • 1st Edition
    • Cyren Rico
    • English
    Plant Exposure to Engineered Nanoparticles: Uptake, Transformation, Molecular and Physiological Responses discusses the long-term exposure of plants, including agronomic crops, to nanomaterials in terrestrial environments. Chapters discuss changes in metabolite profiles in plants exposed to engineered nanomaterials, as well as modifications in elemental content of edible portions of plants. Biochemical pathways, root profiles, generational exposure, and biomass productivity are also analyzed in detail. Subsequent chapters cover risks to trophic transfer, as well as human health and ecological functions, before concluding with future approaches to plant-nanomaterial research. The book covers important aspects of the interactions between plant and nanomaterials and will be a valuable resource to scientists and researchers in plant physiology, nanotechnology, agronomy and environmental science.

  • Neuroimaging Anatomy, Part 1: Brain and Skull, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 32-3
    • Tarik F. Massoud
    • English
    In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 1: Brain and Skull. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part one of a two-part series on neuroimaging anatomy that focuses on the brain, with each article addressing a specific area. The issue also includes an article on Brain Connectomics: the study of the brain’s structural and functional connections between cells.

  • Human Gonadotropins

    • 1st Edition
    • Laurence A. Cole + 1 more
    • English
    Human Gonadotropins is a must-have reference for basic science researchers looking to maximize their knowledge in this specific field of study. Luteinizing hormone, follicle-stimulating hormone, and human chorionic gonadotropin are essential for reproduction and outlined in detail in this work, covering topics ranging from antibodies and immunoassays, to commercial products and standards, genetics, and receptors and intermediaries for gonadotropins. Dr. Laurence Cole has been recognized for his outstanding research throughout his illustrious career. He has received awards from the Institute for Anticancer Research, Biannual Prize for best research; American Association for Clinical Chemistry, Most Outstanding Research Contributor to Clinical Chemistry Prize; Gynecology Oncology, Outstanding Speaker Award; and International Society for Study of Trophoblastic Disease, Gold Medal for most outstanding research. This detailed resource compiles all the recent research together into one volume, with one consistent voice.

  • Carotenoids: Carotenoid and Apocarotenoid Analysis

    • 1st Edition
    • English
    Carotenoids: Carotenoid and Apocarotenoid Analysis, Volume 670, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume covering Getting to know carotenoids, Laser capture of tissues for micro-scale carotenoid analyses, Metabolic engineering of carotenoids: procedures for metabolomic characterization, LC-MS analysis of intracellular metabolites for precursors to the carotenoid pathway, Use of E. coli to produce carotenoid standards, HPLC analysis of carotenoids from Bacteria, Purification and development of standards for carotenoid quantification in plant tissues, and much more. Additional sections in this release cover Ultra-High Performance Liquid Chromatography-Mass Spectrometry Analysis of Plant Apocarotenoids, Detection and analysis of novel and known volatile plant apocarotenoids, Carotenoid extraction, detection, and analysis in citrus, Strategies For The Separation And Tentative Identification Of Geometrical (Cis/Trans, Z/E) Isomers Of Carotenoids, Use of stable isotopes to study bioconversion and bioefficacy of pro-vitamin A carotenoids, Carotenoid extraction and analysis of blood plasma/serum, and more.</P>

  • Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

    • 1st Edition
    • Sandeep Kumar Singh + 2 more
    • English
    Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.

  • MicroRNA

    From Bench to Bedside
    • 1st Edition
    • Junjie Xiao
    • English
    MicroRNA: From Bench to Bedside provides an in-depth, expansive overview of microRNA from fundamentals to clinical practice. It presents researchers with detailed insights on the topic of microRNA, exploring foundational knowledge that is followed by methodologies and the latest technologies for research and potential theragnostic and therapeutic applications for specific diseases. The book consists of eight parts, beginning with an introduction to microRNA and the current state of the field, followed by sections on biogenesis and maturation of microRNA, and methodology and bioinformatics, where chapters focus on isolation and detection techniques. Sections then move on to molecular mechanisms and gene regulation, considering topics such as transcriptional regulation and epigenetic regulation, as well as the role of microRNA as biomarkers. Additionally, microRNA and human disease and microRNA-based therapeutics are explored, focusing on a wide range of diseases such as cancer, age-related disease, cardiovascular disease, microRNA targeted therapy in hepatitis and therapeutic strategies for diabetes. The book concludes with a discussion on advances and future perspectives in microRNA investigation.

  • Systems of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles. This volume discusses cubosomes, proniosomes and niosomes, dendrimerosomes and other new and effective approaches for drug delivery. It will be a valuable title and resource for academics and pharmaceutical scientists, including industrial pharmacists, analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailor-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

  • Spaceflight Associated Neuro-Ocular Syndrome

    • 1st Edition
    • Andrew G. Lee + 1 more
    • English
    Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity-associa... findings collectively define the Spaceflight Associated Neuro-ocular Syndrome (SANS). In this book, the editors compare and contrast prior published work on SANS by the National Aeronautics and Space Administration’s (NASA) Space Medicine Operations Division with retrospective and prospective studies from other research groups. The book describes the possible mechanisms and potential etiologies for SANS, and provides an update and review on the clinical manifestations of SANS including: unilateral and bilateral optic disc edema, globe flattening, choroidal and retinal folds, hyperopic refractive error shifts, and focal areas of ischemic retina (i.e., cotton wool spots). The ocular imaging findings (e.g., retinal nerve fiber layer, optic disc, and choroidal changes on optical coherence tomography) of SANS is also described, including the intraorbital and intracranial findings on orbital ultrasound and magnetic resonance imaging. The knowledge gaps for in-flight and terrestrial human research including potential countermeasures for future stud is also explored, including reports on the in-flight and terrestrial human and animal research being investigated by NASA and its partners to study SANS both prospectively and longitudinally and in preparation for future long duration manned missions to space including the moon, the asteroid belt, or Mars. We think this is a unique topic and hope that NASA and its research partners continue to study SANS in preparation for future longer duration manned space missions.

  • Omics in Horticultural Crops

    • 1st Edition
    • Gyana Ranjan Rout + 1 more
    • English
    Omics in Horticulture Crops presents a comprehensive view of germplasm diversity, genetic evolution, genomics, proteomics and transcriptomics of fruit crops (temperate, tropical and subtropical fruits, fruit nuts, berries), vegetables, tuberous crops, ornamental and floricultural crops and medicinal aromatic plants. Information covering phenomics, genetic diversity, phylogenetic studies, genome sequencing, and genome barcoding through the utilization of molecular markers plays an imperative role in the characterization and effective utilization of diverse germplasm are included in the book. This is a valuable reference for researchers and academics seeking to improve cultivar productivity through enhanced genetic diversity while also retaining optimal traits and protecting the growing environment.

  • Occupational Neurotoxicology

    • 1st Edition
    • Volume 7
    • English
    Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods.

  • Introduction to Basic Aspects of the Autonomic Nervous System

    Volume 1
    • 6th Edition
    • Otto Appenzeller + 2 more
    • English
    Introduction to Basic Aspects of the Autonomic Nervous System, Sixth Edition, Volume One is an all-encompassing reference on the autonomic nervous system's basic function, dysfunction and pathology. This volume describes the anatomy of the autonomic nervous system and its role in the regulation of blood pressure, body temperature, respiration, micturition, digestion and renal function. Additional chapters focus on the autonomic modulation of the neuroendocrine system, sexual function, and immunity. There is also a chapter on mummies and the autonomic nervous system. With these chapters, readers will gain extensive knowledge on the autonomic nervous system's anatomy, functional organization and neurochemistry, which is critical to care for patients with autonomic disorders and guide patient-oriented research.

  • Williams. Nutrición básica y dietoterapia

    • 16th Edition
    • Staci Nix
    • Spanish
    Obra que refleja el carácter evolutivo de la ciencia de la nutrición y de sus directrices basadas en la evidencia. Con un contenido actualizado que sigue las líneas marcadas por la más reciente bibliografía especializada, su objetivo es presentar los principios científicos fundacionales de la nutrición y de sus aplicaciones, orientadas a la atención centrada en la persona. La actualización de los contenidos recoge las mejores prácticas actuales y las directrices basadas en la evidencia más recientes y la iconografía ayuda a comprender los conceptos y la práctica clínica. Incluye diferentes ayudas al aprendizaje como las aperturas de capítulo que centran al estudiante en el objeto de estudio, los cuadros especiales que optimizan la interpretación de los conceptos, los casos clínicos o las guías de dietoterapia, las definiciones de términos clave a lo largo de los capítulos y en un glosario, al final del libro; resúmenes en formato de lista para el repaso, preguntas de opción múltiple y referencias bibliográficas. Dirigido a los estudiantes de los diferentes programas de estudios de Enfermería, y a los técnicos en dietética, también será de utilidad en los programas de otros estudios sanitarios.

  • Applications of Biosurfactant in Agriculture

    • 1st Edition
    • Inamuddin + 1 more
    • English
    Applications of Biosurfactant in Agriculture explores the use of beneficial microorganisms as an alternative to current synthetic plant protection strategies. The book highlights a range of renewable raw substrates including agro-industrial waste as a dependable and cost-effective technology for the mass production of biosurfactant, emphasizes the formulation of biosurfactants using a full-factorial design, scientometric assessment, and presents mathematical modeling for the enhancement of production processes. Recent biotechnological techniques such as functional metagenomics that could help in the molecular characterization of novel biosurfactant with multifunctional activities majorly from uncultured and unexploited microbes available in the soil biosphere are also explored.This book identifies possible modes of action by which nutrients are normally released to plants through the formation of metal-biosurfactant complexes and presents recent research findings on the utilization of biosurfactants for the management of mycotoxins and microorganisms when evaluated in the field and in greenhouses. Finally, the book emphasizes the application of biosurfactants as a form of potent antibiotics for the management of several zoonotic diseases and in animal husbandry.

  • Advances in Parasitology

    • 1st Edition
    • Volume 117
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 118, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. New chapters in this release cover topics such as Parasitic and infectious diseases of African wildlife: The Big Five and Improving Translational Power for Antischistosomal Drug Discovery.

  • Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis

    • 1st Edition
    • William L. Hasler + 2 more
    • English
    Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis comprehensively reviews the clinical features and pathophysiology of cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). This book differentiates the clinical presentation of CVS and CHS from other vomiting syndromes and provides the information necessary to diagnose and effectively treat these disorders. Compiled by expert CVS/CHS clinicians and written by physicians and researchers from several disciplines, this reference provides the most updated, evidence-based approaches, and summarizes the latest research on CVS/CHS. Important topics such as the neural systems that drive nausea and vomiting, clinical features of CVS/CHS including its subtypes, insights into pathogenesis, as well as the curious association of hot-water bathing associated with both of these disorders are all explored. This is a must-have reference for residents and fellows in training, as well as busy clinicians who care for patients with CVS and CHS across multiple care settings including ambulatory clinics, the emergency department, hospitals, and substance use/abuse treatment centers. It is also a useful reference for investigators with an interest in these vomiting disorders.

  • Computational Intelligence in Healthcare Applications

    • 1st Edition
    • Rajeev Agrawal + 4 more
    • English
    Computational Intelligence in Healthcare Applications discusses a variety of techniques designed to represent, enhance and empower inter-domain research based on computational intelligence in healthcare. The book serves as a reference for the pervasive healthcare domain which takes into consideration new convergent computing and other applications. The book discusses topics such as mathematical modeling in medical imaging, predictive modeling based on artificial intelligence and deep learning, smart healthcare and wearable devices, and evidence-based predictive modeling. In addition, it discusses computer-aided diagnostic for clinical inferences and pervasive and ubiquitous techniques in healthcare. This book is a valuable resource for graduate students and researchers in medical informatics, however, it is also ideal for members of the biomedical field and healthcare industry who are interested in learning more about novel technologies and their applications in the field.

  • Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection

    Revolutionary Strategies to Combat Pandemics
    • 1st Edition
    • Arpana Parihar + 4 more
    • English
    Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics compiles information about various computational bioinformatic approaches that can help combat viral infection. The book includes working knowledge of various molecular docking and molecular dynamic simulation approaches that have been exploited for drug repurposing and drug designing purpose. In addition, it sheds light on reverse vaccinomics and immunoinformatic approaches for vaccine designing against SARS-CoV2 infection. This book is an essential resource for researchers, bioinformaticians, computational biologists, computational chemists and pharmaceutical companies who are working on the development of effective and specific therapeutic interventions and point-of-care diagnostic devices using various computational approaches.

  • Evidence-Based Validation of Herbal Medicine

    Translational Research on Botanicals
    • 2nd Edition
    • Pulok K. Mukherjee
    • English
    Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines.

  • Clove (Syzygium aromaticum)

    Chemistry, Functionality and Applications
    • 1st Edition
    • Mohamed Fawzy Ramadan
    • English
    Organized into four sections, Clove (Syzygium aromaticum): Chemistry, Functionality, and Applications addresses the cultivation, composition, and applications of clove, along with the chemistry, functionality, and applications of clove fixed oil, clove essential oil, and clove extracts and their role in food and medicine. Beginning with the introduction of clove, this book aims to establish a multidisciplinary discussion on the development of Syzygium aromaticum phytochemistry, technology, processing, agricultural practices, functional traits, health-enhancing potential, mechanism of action, and toxicity as well as food and nonfood uses. The studies reported in this book confirm the functional applications of Syzygium aromaticum as a medicinal plant, standing out for the significance of novel applications. This book delves into the functional, nutritional, and pharmacological traits of clove. Therefore, the book will serve as a valuable reference for food scientists, technologists, chemists, nutritionists, and pharmacists developing new pharmaceutical and food products.

  • Movement Disorders in Childhood

    • 3rd Edition
    • Harvey S. Singer + 3 more
    • English
    Movement Disorders in Childhood, Third Edition provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. In this new edition, each chapter has been fully revised to include all of the latest scientific and therapeutic advances. Updates include new insights in motor development, control, goal-directed and habitual behaviors, classifications of movements and their complex and integrated circuitry. The authors also discuss developments in pathophysiologic mechanisms, immunology and metabolic disorders. New chapters include coverage of genetics of movement disorders and movement disorders in psychiatric conditions.Appendice... include an updated and revised drug index and genetic search strategy. An updated Companion website hosts selected educational videos to help diagnose movement disorders.

  • Nuclear Medicine and Molecular Imaging

    • 1st Edition
    • Alberto Signore
    • English
    Nuclear Medicine and Molecular Imaging offers complete coverage of this exciting and key area of biomedicine, seamlessly fusing the science behind nuclear medicine with the clinical aspects of diagnostic imaging. Beginning with sections on the physics related to nuclear medicine, radiation biology/safety, and instrumentation/qual... control, it then covers radiochemistry and the development of new radionuclide therapy/tracers, and basic techniques such as positron emission tomography (PET) and single photon emission computed tomography (SPECT). The focus then shifts to the clinical aspects, with sections on clinical/preclinical nuclear imaging (structured via organ system such as gastrointestinal, cardiovascular, pulmonary, etc.), as well as other in vivo molecular imaging techniques such as optical imaging, digital image analysis (radiomics), as well as the increasing use of artificial intelligence (AI) in diagnostics. No other publication provides such a complete overview of the field, with most choosing to focus either on physics or imaging. In most cases, preclinical/experime... imaging is treated separately from clinical imaging. Nuclear Medicine and Molecular Imaging brings it all together into a complete, 4-volume, foundational resource for researchers and medical professionals specializing in this exciting area.

  • Human-Gut Microbiome

    Establishment and Interactions
    • 1st Edition
    • Gunjan Goel + 2 more
    • English
    Human-Gut Microbiome: Establishment and Interactions gives an overview of microbiome establishments in humans and basic technologies used to decipher the structure and function of gut microbiome. Other sections focus on the application of microbiomics in different disease manifestations, such as obesity, diabetes, and more. The book provides the basics, as well as mechanistic knowledge underpinning the structural and functional understanding of the microbiome. With the advancement in omics technologies, as well as the development of bioinformatic tools, much research has been undertaken to decipher the microbiomes of different hosts. This research is generating valuable insights into micro-ecological niches and their impact on humans, hence this new release covers these new insights. The book will be a valuable resource for scientists, researchers, postgraduate and graduate students who are interested in understanding the impact and importance of the omics approach to humans and their microbiomes.

  • Spine Phenotypes

    • 1st Edition
    • Dino Samartzis + 2 more
    • English
    The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry.

  • Allgemeine und spezielle Pharmakologie und Toxikologie

    • 13th Edition
    • Klaus Aktories + 3 more
    • German
    Wer mit „Aktories" lernt, versteht Das Standardwerk der Pharmakologie und Toxikologie in überarbeiteter 13. Auflage: das gesamte Wissen auf über 1.000 Seiten. Bewährt als erstklassiges Lehrbuch für Medizin- und Pharmaziestudierende... begehrt als Nachschlagewerk für Medizinier*innen und Pharmakolog*innen. Das gesamte Wissen der Pharmakologie und Toxikologie wird Ihnen hier verständlich und anschaulich erklärt und bringt Ihnen Sichherheit beim Lernen: Arzneimittelwirkunge... im Gesamtzusammenhang begreifen: Wirkmechanismen und pathophysiologische Bezüge in jedem Kapitel Zusammenhänge verstehen: Ausführliches Kapitel zur allgemeinen Pharmakologie und Toxikologie erleichtert Ihnen das Verständnis der speziellen pharmakologischen Zusammenhänge Praktische Relevanz: Empfehlungen zu Therapie und Dosierungen finden Sie in farbig hervorgehobenen Kästen Neu in der 13. Auflage: Hoch aktuelle Darstellung der Biologika (= das Gebiet der Pharmakologie, das am schnellsten wächst): signifikante Neuentwicklungen für die Tumortherapie, der Therapie rheumatischer Erkrankungen und anderer Autoimmunerkrankunge... der Therapie allergischer Erkrankungen und der Therapie der Psoriasis (Schuppenflechte) Bemerkenswerte Erkenntnisse bei der Einführung der SGLT-2-Inhibitoren (Sodium-Glucose-Like... 2) in der Diabetes-Typ2-Therap... Darstellung der vielfältigen Zusammenhänge von molekular-pharmakolo... Wirkungen der Arzneimittel und ihrer therapeutischen Anwendung (inklusive der mRNA-Technologie) Neue Arzneimittelentwickl... Ergänzung der IMPP-Arzneistofflist... (Markierung im Fließtext + eigenes Register)

  • Coronavirus Drug Discovery

    Volume 2: Antiviral Agents from Natural Products and Nanotechnological Applications
    • 1st Edition
    • Chukwuebuka Egbuna
    • English
    Coronavirus Drug Discovery, Volume Two: Antiviral Agents from Natural Products and Nanotechnological Applications presents detailed information on drug discovery against COVID-19. Sections in this volume present chapters that focus on the various antiviral agents from natural products that have the propensity to be used as chemical scaffolds for the development of drugs against COVID-19. Also captured are the dietary sources of antioxidant bioactives that may help boost the immune system for the management of COVID-19. Other chapters describe the application of nanotechnology for efficient and effective delivery of drugs against COVID-19. Written by global team of experts, this book is an excellent resource for drug developers, medicinal chemists, pharmaceutical companies in R&D and research institutes in both academia and industry.

  • Methods in Stem Cell Biology - Part A

    • 1st Edition
    • Volume 170
    • English
    Methods in Cancer Stem Cell Biology: Part A, Volume 170 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Essential Neuromodulation

    • 2nd Edition
    • Jeffrey Arle + 1 more
    • English
    Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, residents, fellows, bioengineers and basic clinical practitioners. This second edition expands on developments in the field since 2011, emphasizing essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications and complication avoidance. As neuromodulation remains an exciting and rapidly advancing field, this information is critical for neurosurgeons, neurophysiologists, bioengineers and other proceduralists.

  • Protein Interaction Networks

    • 1st Edition
    • Volume 131
    • Rossen Donev
    • English
    Protein Interaction Networks, Volume 131 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

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