Brenner and Stevens’ Pharmacology
- 6th Edition - February 1, 2022
- Imprint: Elsevier
- Author: Craig W. Stevens
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 7 5 8 9 8 - 7
More detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens’ Pharmacology, 6th Edition, focuses on the essential principles you… Read more
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Institutional subscription on ScienceDirect
Request a sales quoteMore detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens’ Pharmacology, 6th Edition, focuses on the essential principles you need to know in a concise, easy-to-understand manner. Authored by Craig W. Stevens, PhD, this highly illustrated introductory text helps you learn and retain key information in pharmacology—taking you from course exams and the USMLE Step 1 right through to clinical practice. New and extensively revised content keeps you up to date with the latest pharmacologic mechanisms and applications.
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Teaches the fundamental aspects of pharmacology using full-color illustrations, detailed explanations, and a consistent format to present classification of drugs for each system/disease.
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Helps you understand both the basic science foundations and clinical applications of pharmacology, with useful tables, drug classifications boxes, case studies, and self-assessments in each chapter to help you review and prepare for course exams and Step 1.
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Includes the latest drugs and therapeutic indications (more than 100 are new to this edition), along with an entirely new chapter on recent developments of immunopharmacology drugs, including antivirals and vaccinations.
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Addresses key topics such as antiviral and monoclonal drugs to treat COVID-19, the opioid epidemic, and gene therapy.
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Features more than 700 new and updated images, with many revised figures focused on clearing presenting the mechanism of action of drugs.
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Includes access to bonus eBook content such as animations, an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style self-assessment questions, and more.
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Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Medical students
- Instructions for online access
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Section I. PRINCIPLES OF PHARMACOLOGY
- CHAPTER 1. Introduction to Pharmacology and Drug Names
- Pharmacology and Related Sciences
- Drug Sources And Preparations
- Routes of Drug Administration
- Drug Names
- Summary of Important Points
- CHAPTER 2. Pharmacokinetics or What the Body Does to the Drug
- Overview
- Drug Absorption
- Drug Distribution
- Drug Metabolism
- Drug Excretion
- Quantitative Pharmacokinetics
- Single-Dose Pharmacokinetics
- Continuous-Dose and Multiple-Dose Kinetics
- Summary of Important Points
- CHAPTER 3. Pharmacodynamics or What the Drug Does to the Body
- Overview
- Nature of Drug Receptors
- Drug-Receptor Interactions
- Dose-Response Relationships
- Summary of Important Points
- Chapter 4. Drug Development and Drug Safety
- Overview
- Drug Development
- The Investigational New Drug Application
- Federal Drug Laws And Regulations
- Adverse Effects Of Drugs
- Drug Interactions
- Factors Affecting Drug Safety And Efficacy
- Summary Of Important Points
- CHAPTER 5. Toxicology Principles and the Treatment of Poisoning
- Overview
- Treatment Of Poisoning
- Summary Of Important Points
- Section II. AUTONOMIC AND NEUROMUSCULAR PHARMACOLOGY
- Chapter 6. Parasympathetic, Neuromuscular Pharmacology, and Cholinergic Agonists
- Overview
- Anatomy And Physiology Of The Peripheral Nervous System
- Neurotransmission And Sites Of Drug Action
- Acetylcholine Receptors
- Acetylcholine Agonists
- Summary Of Important Points
- Chapter 7. Cholinergic Receptor Antagonists
- Overview
- Muscarinic Receptor Antagonists
- Nicotinic Receptor Antagonists
- Summary Of Important Points
- Chapter 8. Sympathetic Neuropharmacology and Adrenergic Agonists
- Overview
- Drugs Affecting Adrenergic Neurotransmission
- Adrenoceptor Agonists
- Signal Transduction
- Classification Of Adrenoceptor Agonists
- Summary Of Important Points
- Chapter 9. Adrenergic Receptor Antagonists
- Overview
- α-Adrenoceptor Antagonists
- β-Adrenoceptor Antagonists
- α- And β-Adrenoceptor Antagonists
- Summary Of Important Points
- Section III. CARDIOVASCULAR, RENAL, AND HEMATOLOGIC PHARMACOLOGY
- CHAPTER 10. Antihypertensive Drugs
- Overview
- Diuretics
- Sympatholytic Drugs
- Angiotensin Inhibitors
- Vasodilators
- The Management of Hypertension
- Summary of Important Points
- Chapter 11. Antianginal Drugs
- Overview
- Vasodilators
- Beta-Adrenoceptor Antagonists
- Other Antianginal Agents
- Management of Angina Pectoris
- Summary of Important Points
- Chapter 12. Drugs for the Treatment of Heart Failure
- Overview
- Positively Inotropic Drugs
- Vasodilators
- BETA-Adrenoceptor Antagonists
- Aldosterone Antagonists
- Diuretics
- Management of Heart Failure
- Summary of Important Points
- CHAPTER 13. Diuretic Drugs
- Overview
- Nephron Function and Sites of Drug Action
- Diuretic Agents
- Management of Edema
- Summary of Important Points
- Chapter 14. Drugs for Cardiac Dysrhythmia
- Overveiw
- Sodium Channel Blockers
- Management of Dysrhythmias
- Summary of Important Points
- CHAPTER 15. Drugs for Hyperlipidemia
- Overview
- Drugs For Hypercholesterolemia
- Drugs For Familial Hypercholesterolemia and Leptin Deficiency
- Summary of Important Points
- Chapter 16. Antithrombotic and Thrombolytic Drugs
- Overview
- Anticoagulant Drugs
- Antiplatelet Drugs
- Summary of Important Points
- CHAPTER 17. Hematopoietic Drugs
- Overview
- Hematopoietic Drugs
- Drugs for Sickle Cell Disease
- Summary of Important Points
- Section IV. CENTRAL NERVOUS SYSTEM PHARMACOLOGY
- Chapter 18. Introduction to Central Nervous System Pharmacology
- Overview
- Neurotransmission in the Central Nervous System
- Mechanisms of Drug Action
- Neuronal Systems in the Central Nervous System
- Summary of Important Points
- Chapter 19. Sedative-Hypnotic and Anxiolytic Drugs
- Overview
- Anxiety Disorders
- Sleep Disorders
- Sedative-Hypnotic Drugs
- Summary of Important Points
- Chapter 20. Antiepileptic Drugs
- Overview
- Treatment of Seizure Disorders
- The Management of Seizure Disorders
- Summary of Important Points
- Chapter 21. Local and General Anesthetics
- Overview
- Local Anesthetics
- General Anesthetics
- Summary of Important Points
- Chapter 22. Psychotherapeutic Drugs
- Overview
- Schizophrenia
- Antipsychotic Drugs
- Affective Disorders
- Antidepressant Drugs
- Mood-Stabilizing Drugs
- Central Nervous System Stimulants
- Summary of Important Points
- Chapter 23. Opioid Analgesics and Antagonists
- Overview
- Pain and Analgesic Agents
- Pain Pathways
- Opioid Peptides and Receptors
- Opioid Drugs
- Specific Agents
- The Treatment of Pain
- Summary of Important Points
- Chapter 24. Drugs for Neurodegenerative Diseases
- Overview
- Parkinson Disease
- Alzheimer Disease
- Huntington Disease
- Multiple Sclerosis
- Amyotrophic Lateral Sclerosis
- Antispastic Agents
- Summary of Important Points
- Chapter 25. Drugs of Abuse
- Overview
- Central Nervous System Depressants
- Central Nervous System Stimulants
- Other Psychoactive Drugs
- Prescription Drug Abuse
- OTC Drugs of Abuse
- Steroid Drug Abuse
- Inhalant Abuse
- Management of Drug Abuse
- Summary of Important Points
- Section V. PHARMACOLOGY OF RESPIRATORY AND OTHER SYSTEMS
- Chapter 26. Autacoid Drugs That Mimic Endogenous Substances
- Overview
- Histamine and Related Drugs
- Antihistamine Drugs
- Serotonin and Related Drugs
- Eicosanoids and Related Drugs
- Eicosanoid Drugs
- Endothelin-1 Antagonists
- Summary of Important Points
- Chapter 27. Pharmacological Treatment of Respiratory Disorders
- Overview
- Anti-Inflammatory Drugs
- Bronchodilators
- Monoclonal Antibodies
- Management of Asthma
- Antitussives
- Expectorants
- Management of Rhinitis
- Drugs for Cystic Fibrosis
- Summary of Important Points
- Chapter 28. Pharmacological Treatment of Gastrointestinal Disorders
- Overview
- Drugs for Peptic Ulcer Disease
- Treatment of Helicobacter pylori Infection
- Drugs for Inflammatory Bowel Diseases
- Drugs for Constipation
- Antidiarrheal Agents
- Drugs for Nausea and Vomiting
- Summary of Important Points
- Chapter 29. Drugs for Headache Disorders
- Overview
- Characteristics and Pathogenesis of Migraine Headaches
- Drugs for Migraine Headaches
- Drugs for Migraine Prevention
- Drugs for Migraine Termination
- Guidelines for Managing Migraine Headaches
- Characteristics and Treatment of Cluster Headaches
- Characteristics and Treatment of Tension Headaches
- Summary of Important Points
- Chapter 30. Drugs for Pain, Inflammation, and Arthritic Disorders
- Overview
- Rheumatoid Arthritis
- Osteoarthritis
- Gout
- Nonsteroidal Anti-Inflammatory Drugs
- Disease-Modifying Antirheumatic Drugs
- Drugs for the Treatment of Gout
- Summary of Important Points
- Section VI. ENDOCRINE PHARMACOLOGY
- Chapter 31. Hypothalamic and Pituitary Hormone Drugs
- Overview
- Anterior Pituitary Hormones
- Posterior Pituitary Hormones
- Summary of Important Points
- Chapter 32. Drugs for the Treatment of Thyroid Disorders
- Overview
- Thyroid Disorders
- Thyroid Hormone Preparations
- Antithyroid Agents
- Drugs for Thyroid Treatment After Nuclear Reactor Accident or Nuclear Bomb Explosion
- Summary of Important Points
- Chapter 33. Adrenal Steroids and Related Drugs
- Overview
- Synthesis and Secretion of Adrenal Steroids
- Physiologic Effects of Adrenal Steroids
- Corticosteroid Drugs
- Adrenal Androgens
- Corticosteroid Synthesis Inhibitors
- Corticosteroid Receptor Antagonists
- Dhea Use in Older Men
- Summary of Important Points
- Chapter 34. Fertility and Reproduction Drugs
- Overview
- Estrogens and Progestin Drugs
- Contraceptives
- Selective Estrogen Receptor Modulators
- Antiprogestins
- Aromatase Inhibitors
- Androgens
- Antiandrogens
- Agents for Treating Dysmenorrhea and Female Sexual Dysfunction
- Drug Therapy for Hirsutism and Gender Transition
- Drugs Used in Obstetrics
- Summary of Important Points
- Chapter 35. Drugs for the Treatment of Diabetes
- Overview
- Diabetes
- Insulin Preparations
- Other Antidiabetic Agents
- Dopamine Agonist
- Management of Diabetes
- Summary of Important Points
- Chapter 36. Drugs Affecting Calcium and Bone Formation
- Overview
- Pharmacologic Agents
- Management of Calcium and Bone Disorders
- Summary of Important Points
- Section VII. ANTIMICROBIAL AND CHEMOTHERAPEUTIC AGENTS
- Chapter 37. Principles of Antimicrobial Chemotherapy
- Overview
- Classification of Antimicrobial Drugs
- Antimicrobial Activity
- Microbial Sensitivity and Resistance
- Selection of Antimicrobial Drugs
- Combination Drug Therapy
- Prophylactic Therapy
- Summary of Important Points
- Chapter 38. Antibiotics That Inhibit Bacterial Cell Wall Synthesis
- Overview
- β-Lactam Antibiotics
- Other Bacterial Cell Wall Synthesis Inhibitors
- Summary of Important Points
- Chapter 39. Antibiotics That Inhibit Bacterial Protein Synthesis
- Overview
- Sites of Drug Action
- Drugs That Affect the 30s Ribosomal Subunit
- Drugs That Affect the 50s Ribosomal Subunit
- Other Protein Synthesis Inhibitors
- Summary of Important Points
- Chapter 40. Other Antimicrobial Agents Such as Quinolones and Antifolate Drugs
- Overview
- Antifolate Drugs
- Fluoroquinolones
- Adverse Effects and Interactions
- Other Antibacterial Drugs
- Summary of Important Points
- Chapter 41. Antimycobacterial Drugs for Treating Tuberculosis and Other Diseases
- Overview
- Mycobacterial Infections
- Drugs For Mycobacterial Infections
- Drugs for M. Avium-intracellulare Infections
- Drugs For Leprosy
- Summary of Important Points
- Chapter 42. Drugs for the Treatment of Fungal Infections
- Overview
- Clinical Uses and Mechanisms of Antifungal Drugs
- Antifungal Drugs
- Summary of Important Points
- Chapter 43. Drugs for the Treatment of Viral Infections
- Overview
- Drugs for Herpesvirus Infections
- Pharmacokinetics and Indications
- Drugs for Human Immunodeficiency Virus Infection
- Drugs for Influenza
- Drugs for Hepatitis and Other Viral Infections
- Drugs for Smallpox Infections
- Treatment of Sars-Cov-2 Infections
- Summary of Important Points
- Chapter 44. Drugs for the Treatment of Parasites
- Overview
- Drugs for Infections Caused By Lumen- and Tissue-Dwelling Protozoa
- Drugs for Infections Caused by Blood- and Tissue-Dwelling Protozoa
- Drugs for Infections Caused By Helminths
- Summary of Important Points
- Chapter 45. Antineoplastic Agents
- Overview
- Principles of Cancer Therapy
- Antineoplastic Drugs
- Small Molecule Inhibitors
- Hormonal Agents
- Summary of Important Points
- Chapter 46. Immunopharmacology, Biologicals, and Gene Therapy
- Overview
- Monoclonal Antibody Drugs
- Biologicals
- Gene Therapy Agents
- Summary of Important Points
- Answers and Explanations
- Index
- Edition: 6
- Published: February 1, 2022
- Imprint: Elsevier
- No. of pages: 624
- Language: English
- Paperback ISBN: 9780323758987
CS
Craig W. Stevens
Craig W. Stevens, Ph.D. is a professor of Pharmacology at Oklahoma State University and is co-author of Brenner and Stevens’ Pharmacology, a popular pharmacology textbook now in its 5th Edition. He also wrote and edited two books on G-protein coupled receptors entitled Methods for the Discovery and Characterization of G Protein-Coupled Receptors (Springer Protocols, 2011) and G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era (Springer Methods in Pharmacology and Toxicology, 2014). He has just finished working on a new book for the Science and Technology Pharmacology list called The Drug Expert: A Practical Guide to the Impact of Drug Use in Legal Proceedings which is a guide for pharmacologists aiming to be successful as drug litigation consultants and a helpful book for the lawyers that hire them. Dr. Stevens maintains a second career as an expert witness in Pharmacology (Drug Expert) and has consulted for lawyers on over 80 cases in both criminal and civil proceedings.
Affiliations and expertise
Professor of Pharmacology, Department of Pharmacology and Physiology, Oklahoma State University-Center for Health Sciences, Tulsa, OK, USA