Tailor-Made Polysaccharides in Drug Delivery
- 1st Edition - September 2, 2022
- Editors: Amit Kumar Nayak, Md Saquib Hasnain
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 2 8 6 - 8
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 1 2 8 7 - 5
Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharma… Read more
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Request a sales quoteTailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.
The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.
The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.
- Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications
- Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides
- Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides
Postgraduate students, postdoctoral research fellows, pharmaceutical scientists including industrial pharmacists and analytical scientists, chemical engineers and regulatory scientists actively involved in drug delivery and process development of polymers for drug delivery
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- About the editors
- Preface
- Chapter 1: Synthesis of tailor-made polysaccharides: An overview
- Abstract
- Chapter 1: Introduction
- 2: Syntheses of tailor-made polysaccharides
- 3: Conclusion
- References
- Chapter 2: Drug delivery dosage forms made of tailor-made natural polysaccharides
- Abstract
- 1: Introduction
- 2: Tablets made of tailor-made natural polysaccharides
- 3: Nanoparticles made of tailor-made natural polysaccharides
- 4: Microparticles made of tailor-made natural polysaccharides
- 5: Beads made of tailor-made natural polysaccharides
- 6: Hydrogels made of tailor-made natural polysaccharides
- 7: Miscellaneous
- 8: Conclusion
- References
- Further reading
- Chapter 3: Carboxymethylated polysaccharides in drug delivery
- Abstract
- 1: Introduction
- 2: Carboxymethylation process
- 3: Carboxymethyl polysaccharides in drug delivery
- 4: Conclusion
- References
- Chapter 4: Thiolated polysaccharides in drug delivery
- Abstract
- 1: Introduction
- 2: Various thiolated polysaccharides used in drug delivery formulations
- 3: Conclusion
- References
- Chapter 5: Cross-linked polysaccharides in drug delivery
- Abstract
- 1: Introduction
- 2: Cross-linking of and the cross-linked polysaccharides
- 3: Cross-linked polysaccharides applied in DDSs
- 4: Smart cross-linking strategies
- 5: Conclusion
- References
- Chapter 6: Graft copolymers of polysaccharides: Synthesis techniques and pharmaceutical applications
- Abstract
- 1: Introduction
- 2: Polysaccharides
- 3: Graft copolymers and different techniques of polymer grafting
- 4: Properties of graft copolymers
- 5: Pharmaceutical applications of polysaccharide graft copolymers
- 6: Conclusion
- References
- Chapter 7: Grafted polysaccharides in drug delivery
- Abstract
- 1: Introduction
- 2: Polysaccharide-based graft copolymers
- 3: Grafted polysaccharides in DDSs
- 4: Conclusion
- References
- Chapter 8: Polysaccharide-based polyelectrolyte complex systems in drug delivery
- Abstract
- 1: Introduction
- 2: What is a polyelectrolyte complex?
- 3: Advantages of PECs
- 4: Factors affecting the formation and stability of PECs
- 5: Polysaccharides used to fabricate polyelectrolyte complexes (PECs)
- 6: Various dosage forms fabricated by polyelectrolyte complexation
- 7: Conclusion
- References
- Chapter 9: Polysaccharide-based interpenetrating polymeric network systems in drug delivery
- Abstract
- 1: Introduction
- 2: IPNs: Definition, properties, and classifications
- 3: Chitosan-based IPN systems in drug delivery
- 4: Alginate-based IPN systems in drug delivery
- 5: Pectin-based IPN systems in drug delivery
- 6: Gellan gum-based IPN systems in drug delivery
- 7: Locust bean gum-based IPN systems in drug delivery
- 8: Xanthan gum-based IPN systems in drug delivery
- 9: Carrageenan-based IPN systems in drug delivery
- 10: Conclusion
- References
- Chapter 10: Polysaccharide nanoconjugates in drug delivery
- Abstract
- 1: Introduction
- 2: Polysaccharide nanoconjugates
- 3: Advantages of polysaccharide nanoconjugates in drug delivery
- 4: Polysaccharide used for nanoconjugation
- 5: Recent progress
- 6: Conclusion
- References
- Chapter 11: Functionalized chitosan in drug delivery
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Functionalized chitosan derivatives as drug delivery systems
- 3: Conclusion
- References
- Chapter 12: Modified alginates in drug delivery
- Abstract
- 1: Introduction
- 2: Alginate biopolymer
- 3: Physicochemical heterogeneity toward drug delivery
- 4: Biological synergistic attributes toward drug delivery
- 5: Modification of alginate
- 6: Application of modified alginate in drug delivery
- 7: Concluding remarks
- 8: Future directions
- References
- Chapter 13: Uses of tailor-made plant starches in drug delivery
- Abstract
- 1: Introduction
- 2: Starch: Basic chemistry and properties
- 3: Plant-derived starches as pharmaceutical excipients in drug delivery
- 4: Synthesis of tailor-made plant starches and their uses in drug delivery
- 5: Clinical potential of tailor-made starches
- 6: Conclusion
- References
- Chapter 14: Cancer targeting by tailor-made polysaccharides
- Abstract
- 1: Introduction
- 2: Polysaccharides and their importance
- 3: Tailor-made chitosan-based systems for cancer-targeting applications
- 4: Tailor-made hyaluronic acid-based systems for cancer-targeting applications
- 5: Tailor-made pectin-based systems for cancer-targeting applications
- 6: Tailor-made heparin-based systems for cancer-targeting applications
- 7: Tailor-made dextran-based systems for cancer-targeting applications
- 8: Tailor-made chondroitin sulfate-based systems for cancer-targeting applications
- 9: Tailor-made cyclodextrin-based systems for cancer-targeting applications
- 10: Tailor-made pullulan-based systems for cancer-targeting applications
- 11: Tailor-made alginate-based systems for cancer-targeting applications
- 12: Tailor-made amylose-based systems for cancer-targeting applications
- 13: Conclusion
- References
- Chapter 15: Delivery of genes and growth factors using tailor-made polysaccharides
- Abstract
- 1: Introduction
- 2: Polysaccharides
- 3: Gene therapy and applications of tailor-made polysaccharides for gene delivery
- 4: Growth factors and applications of tailor-made polysaccharides for growth delivery
- 5: Conclusion
- References
- Index
- No. of pages: 414
- Language: English
- Edition: 1
- Published: September 2, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780128212868
- eBook ISBN: 9780128212875
AN
Amit Kumar Nayak
Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.
Affiliations and expertise
Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, IndiaMH
Md Saquib Hasnain
Prof. (Dr.) Md Saquib Hasnain has over 13 years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches and many more. Till date he has authored over 100 publications in various high impact peer-reviewed journals, more than 100 book chapters and 30 books to his credit. He is also serving as the reviewer of several prestigious journals. Overall, he has earned a highly impressive publishing and cited record. He has also participated and presented his research work at over ten conferences in India, and abroad. He was also a member of scientific societies i.e., Royal Society of Chemistry, Great Britain, International Association of Environmental and Analytical Chemistry, Switzerland and Swiss Chemical Society, Switzerland.
Affiliations and expertise
Department of Pharmacy, Marwadi University, Rajkot, Gujarat, IndiaRead Tailor-Made Polysaccharides in Drug Delivery on ScienceDirect