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Advances in Immunology
1st Edition - August 26, 2022
Editor: Frederick W. Alt
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 9 4 3 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 9 4 4 - 2
Advances in Immunology, Volume 154, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in… Read more
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Advances in Immunology, Volume 154, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering Regulatory T Cells in Infection and Factor H and Properdin and their regulation.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding and respected serial on the subject matter
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter One: Antibody-mediated immunity to SARS-CoV-2 spike
- Abstract
- 1: The SARS-CoV-2 pandemic
- 2: Overview of SARS-CoV-2
- 3: Monoclonal antibodies targeting the receptor-binding domain of spike
- 4: Monoclonal antibodies to the N-terminal domain of spike
- 5: Monoclonal antibodies targeting S2
- 6: Conclusions
- References
- Chapter Two: The role of B cells in the development, progression, and treatment of lymphomas and solid tumors
- Abstract
- 1: Overview of B cell development and differentiation
- 2: B cells in solid tumors
- 3: Pathogenesis of B cell lymphomas
- 4: Conclusion
- References
- No. of pages: 126
- Language: English
- Published: August 26, 2022
- Imprint: Academic Press
- Hardback ISBN: 9780323989435
- eBook ISBN: 9780323989442
FA
Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA