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An Insider's Perspective of Prostate Cancer
Understanding Effects, Management Options and Consequences
- 1st Edition - September 3, 2022
- Author: Robert Alexander (‘Frank’) Gardiner
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 8 7 0 9 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 8 4 1 3 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 8 7 1 0 - 0
An Insider’s Perspective of Prostate Cancer: Understanding Effects, Management Options and Consequences provides scientifically based information on the management and treatment… Read more
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Request a sales quoteAn Insider’s Perspective of Prostate Cancer: Understanding Effects, Management Options and Consequences provides scientifically based information on the management and treatment of prostate cancer. The text is designed to be neither prescriptive nor proscriptive, providing succinct, yet comprehensive details in ‘bite size chunks’ for ready assimilation and application. Sections cover recent approaches the prostate cancer landscape has made by providing background statistical and anatomical information that is followed by relevant genetic, immunological and background data. The book then proceeds to explain the mechanisms involved with cancer development and the spread and metastases that can occur in a minority of those diagnosed.
In addition to acknowledging the importance of psychological effects of diagnosis and management interventions, the undervalued benefits of exercise are also emphasized, including information on holistic management. This comprehensive approach makes this a perfect reference for up-to-date information on all aspects of prostate cancer and its management.
- Provides succinct, yet comprehensive coverage on the management and treatment of prostate cancer and subsequent consequences for patients
- Reviews how prostate cancers change and how treatments can adapt
- Delivers guidance on how to assess information with ranking in terms of levels of evidence, thus enabling the evaluation of critical reports and claims made in relation to prostate cancer and other conditions
Tertiary educated readers with a particular interest in prostate cancer such as GPs and urological trainees
- Cover Image
- Title Page
- Copyright
- Table of Contents
- Foreword
- Preface
- Acknowledgements & dedication
- Chapter 1 Introduction
- 1.1 The spectrum of prostate cancers
- 1.2 Diagnosis in the clinical context
- Chapter 2 The “lie of the land”
- 2.1 Origin of the prostate
- 2.2 Anatomical considerations
- 2.3 Normal microscopical appearances
- 2.4 Functional relationships
- 2.5 Functional changes due to previous surgery
- Chapter 3 The background to cancer
- 3.1 What is cancer?
- 3.2 Genes and cancer
- 3.3 Microscopic appearances
- 3.4 Cell replication and the cell cycle
- 3.5 Immunological competence
- Chapter 4 How cancer cells progress and spread & factors in management
- 4.1 Feeding faster-replicating cancer cells
- 4.2 How cancer cells spread
- 4.3 Prostate cancer's preferred sites for metastases
- 4.4 Patient distress, psychological issues, and survivorship
- 4.5 Staging prostate cancer
- 4.6 Determining and evaluating forms of management
- Chapter 5 Localised treatments for prostate cancer
- 5.1 Prostate cancer stratification
- 5.2 Active Surveillance
- 5.3 Radical prostatectomy
- 5.4 Radiation therapy
- 5.5 Focal therapy as a primary intervention
- 5.6 Fear of recurrence
- Chapter 6 First-line androgen deprivation therapy (ADT)
- 6.1 Hypogonadism (testosterone deficiency) with ageing
- 6.2 Forms of androgen deprivation therapy
- 6.3 Bilateral orchidectomy (bilateral orchiectomy)
- 6.4 Oestrogens/estrogens
- 6.5 LHRH agonists and antagonists
- 6.6 Unwanted effects of LHRH agonists and antagonists
- Chapter 7 Castrate resistant prostate cancer (CRPC)
- 7.1 Emergence of castrate-resistant prostate cancer
- 7.2 Diagnosis of CRPC
- 7.3 Earlier strategies
- 7.4 Newer generation antiandrogens: androgen receptor signalling inhibitors
- 7.5 Systemic radiation therapy—Theranostics
- 7.6 Chemotherapy
- 7.7 Immunotherapy
- Chapter 8 Holistic medical management
- 8.1 Survivorship
- 8.2 Palliative Care
- Chapter 9 Summary and conclusions— thoughts on the future
- Glossary
- References
- Addendum
- Index
- No. of pages: 166
- Language: English
- Edition: 1
- Published: September 3, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780443187094
- eBook ISBN: 9780443284137
- eBook ISBN: 9780443187100
RG
Robert Alexander (‘Frank’) Gardiner
Emeritus Professor Robert Alexander (‘Frank’) Gardiner AM, MD, BS, FRCS, FRACS is a retired academic urologist with an honorary consultant urological appointment at Royal Brisbane & Women’s Hospital and remains based at University of Queensland Centre for Clinical Research for his ongoing research activities. For his international, national and community service activities, research achievements and clinical commitments, he was honored as a Member, Order of Australia (AM) in 2010, received a Medal & Certificate of Outstanding Service to Fellowship by the Royal Australasian College of Surgeons in 2012 and, in 2014, was presented with a Royal Brisbane and Women’s Hospital (RBWH) Distinguished Research Award and made Fellow Urological Society of Australia and New Zealand. Gardiner has been an editorial board member of 7 peer-reviewed international journals fulfilling roles as sub-editor and section editor in two and associate editor in another.
Affiliations and expertise
Emeritus Professor, The University of Queensland; Affiliate Professor, University of Queensland Centre for Clinical Research; Honorary Consultant Urologist, Royal Brisbane & Women’s Hospital; Adjunct Professor, Edith Cowan University, Perth, Western Australia