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Elsevier

Books in Life sciences

  • The Plasticity of Sex

    The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior
    • 2nd Edition
    • Marianne Legato J
    • English
    The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior, Second Edition offers a thorough exploration of the biological, clinical, and social dimensions of human sexuality. This updated edition emphasizes the increasing recognition of the diversity of sexual identities and behaviors, particularly the spectrum between traditional male and female categories. It consolidates evidence-based research on the molecular and developmental biology of sex, gender identity, and sexual behavior, presenting a comprehensive resource for biomedical researchers, clinicians, and medical students. A key theme of this edition is the growing understanding of human sexuality as fluid and diverse, shaped by a variety of genetic, hormonal, and environmental factors. Over recent decades, there has been heightened interest in issues like gender identity, genital ambivalence, and sexual transition, with both the general public and medical professionals seeking more knowledge and guidance on these topics. The book underscores the need for a more inclusive approach, incorporating voices from diverse communities and recognizing the importance of broadening the scope of research beyond narrow sample sizes and traditional binary frameworks. The new edition highlights the ongoing challenges in understanding and addressing variations in human sexuality and the need for continued dialogue between science, society, and legal systems to create more inclusive frameworks for care and support. This work serves as an essential reference for anyone involved in the study or treatment of human sexuality.

  • Remote Sensing and Machine Learning in Conservation

    Applications and Techniques
    • 1st Edition
    • Alireza Sharifi
    • English
    In Remote Sensing and Machine Learning in Conservation: Applications and Techniques, readers will discover how cutting-edge technology is transforming our understanding of the natural world. This book explores how remote sensing and machine learning are being used to monitor wildlife populations, map critical habitats, predict the effects of climate change, and identify poaching hotspots. From the analysis of satellite imagery to the use of drones and artificial intelligence, this book provides a comprehensive overview of the latest tools and techniques available to conservationists. Written by a renowned expert in spatial information research, this book introduces readers to the exciting new possibilities opened by the combination of remote sensing and machine learning. Early chapters provide an overview of both emerging technologies and their integration into habitat mapping, species distribution, environmental monitoring, and climate change adaptation. Central chapters explore real-world applications and case studies for combating poaching, managing urban expansion, controlling invasive species, and more. Final chapters explore the funding and policy landscape and conclude with a reflection on the role of these technologies in transforming conservation practices. By equipping readers with an overview of these technologies, case studies of their real-world applications, and sample code, datasets, and open-source tools, Remote Sensing and Machine Learning in Conservation: Applications and Techniques promotes the innovative use of these technologies to address global environmental challenges. This is an essential resource for conservationists, resource managers, environmental scientists, and academics studying novel technological applications to conservation issues.

  • Artificial Intelligence in Clinical Medicine

    General Concepts and Specific Applications
    • 1st Edition
    • Marianne Legato J + 1 more
    • English
    Artificial Intelligence in Clinical Medicine: General Concepts and Specific Applications explores the evolution and application of artificial intelligence (AI) in medicine, highlighting both its potential and challenges. The initial discussion outlines past failures in integrating AI into healthcare, followed by a review of FDA-approved AI medical devices and their implications for diagnostics. Subsequent sections examine the transformative impact of large language models, the ethical application of AI in clinical settings, and the role of AI in enhancing patient safety. Various specialties, such as cardiology and pulmonary disease, illustrate AI's capabilities in improving diagnostics and treatment. The discussions extend to diabetes care, dermatology, obstetrics, and radiology, emphasizing the need for ethical considerations and quality assessments to ensure AI aligns with human values and improves patient outcomes across diverse healthcare contexts.

  • Omics Applications in Clinical Medicine

    • 1st Edition
    • Luis María Vaschetto
    • English
    Omics-Driven Healthcare: The Future of Medicine is a comprehensive reference piece that explores the potential of personalized medicine, where treatments are tailored to individual patients based on their unique genetic makeup. "Omics-Driven Healthcare: The Future of Medicine" bridges the critical gap between the exponentially growing omics technologies and their practical application in clinical settings. With approximately 18 chapters, this book is designed for advanced students and entry-level researchers in medical genetics and precision medicine who require a thorough understanding of omics technologies and their applications in healthcare. This book is an essential resource for anyone looking to gain insights into the latest advancements and real-world applications of omics technologies, and how these powerful tools are transforming the diagnosis, treatment, and prevention of diseases.

  • Practical Guide to Diagnosing and Treating Ocular Tumors

    • 1st Edition
    • Maura Di Nicola + 1 more
    • English
    Practical Guide to Diagnosing and Treating Ocular Tumors provides practical guidance on the diagnosis and management of ocular tumors. This comprehensive guide highlights the strengths, limitations, and applications of all imaging modalities in ocular oncology. It not only discusses new treatments in ocular oncology (including belzupacap sarotalocan and darovasertib for uveal melanoma, mTOR inhibitors for retinal astrocytic hamartomas in patients with ocular involvement of tuberous sclerosis complex, and belzutifan for retinal hemangioblastomas in patients with Von Hippel Lindau disease), but also offers a comprehensive and practical review of the techniques, complications, and applications of well-established treatments.Ophthalmo... and ocular oncologists will find this to be a practical guide to diagnosing and treating surface and intraocular tumors using a novel approach that will instruct readers on how to utilize and interpret multimodal imaging correctly to diagnose ocular tumors. Readers will gain an understanding of the risks and benefits of different treatment modalities and the most appropriate use scenario in each tumor type.

  • Cellular Therapy for Autoimmune Disease

    • 1st Edition
    • Samik Basu + 1 more
    • English
    Cellular Therapy for Autoimmune Disease provides a comprehensive exploration of the evolving landscape of cellular therapies for autoimmune diseases. The book delves into the evolution of the standard of care for autoimmune diseases, transitioning from chronic suppression to targeted replacement or suppression therapies. It covers a wide array of topics, including stem cell transplants, B-cell and plasma cell depletion strategies, and autologous regulatory and effector T-cell approaches. Additionally, it explores myeloid cellular approaches, allogeneic cellular therapies, and viral or nanoparticle-based strategies. Each chapter provides a thorough examination of mechanisms of action, clinical and non-clinical data, and the associated risks and benefits.Finally, the book addresses unique clinical and manufacturing considerations, offering a roadmap for the future state of cellular therapies in autoimmune diseases. This essential resource addresses the rapid advancements in cell therapies that have outpaced the availability of integrated, up-to-date resources. By bridging the gap between scientific research and clinical applications, it offers in-depth insights into mechanisms of action, disease-specific therapeutic strategies, and the latest innovations in clinical and manufacturing considerations for scientists and clinicians.

  • Inherited Metabolic Diseases and the Brain

    • 1st Edition
    • Fanny Mochel + 2 more
    • English
    Inherited Metabolic Diseases and the Brain explores the latest research on the neurological aspects of inherited metabolic diseases such as epilepsy, encephalotomy and more. With a strong research driven foundation and clinical applications, this book provides a primer which will help practicing pediatric and adult neurologists recognize, diagnose and treat neurometabolic disorders. This volume will also present a number of more common disorders in more detail, describing the variability in clinical presentation, the life course of the disease and the intricacies of diagnosis and treatment.

  • Organic Dairy Farming

    • 1st Edition
    • Manuel Gonzalez Ronquillo + 3 more
    • English
    As a result of increasing awareness and concern for animal welfare and the dangers of pesticides and antibiotics used in some farming systems, today's consumers are increasingly reaching for organic products at their local stores. Organic Dairy Farming describes the processes, practices, and international regulations that ultimately classify a dairy product as organic. The book compares organic and conventional dairy farming systems across a variety of dairy animals, covering cows, sheep, goats, buffaloes, and camelids. It considers the differences in breed selection, animal welfare, and product quality between conventional and organic farming systems. Finally, the book demonstrates the added nutritional value in the profile of fatty acids in organic milk and milk products. Organic Dairy Farming is written and edited by experts in dairy science, nutrition, consumer science, and food regulation. This work will help direct future research in organic dairy farming and products, or even aid stakeholders in implementing organic practices on dairy farms.

  • Herbals and Their Antioxidant Effects on Human Health

    • 1st Edition
    • Süleyman Kaplan
    • English
    Herbals and their Effects on Human Health provides a comprehensive exploration of the diverse bioactive components found in medicinal plants and their relevance to human health. Divided into three distinct sections, beginning with a thorough examination of bioactive components and their health benefits, readers will discover the intricacies of traditional practices such as Ayurveda, the role of phytotherapy in managing metabolic disorders, and the therapeutic potential of antioxidants in various health contexts, including skin health and cardiovascular disease. The book further enhances its scientific rigor by including light and electron microscopic images that illustrate tissue and organ structures affected by herbal interventions. Subsequent sections focus on bioactive foods, highlighting their therapeutic effects through in-depth discussions on specific herbals and plants such as garlic, curcumin, garcinia kola and blueberries. This section not only examines their protective roles in conditions like chronic inflammation and diabetes but also addresses lesser-known foods and their health-promoting properties. The final section highlights the mechanisms of action of these compounds, examining their impact on biological systems and their neuroprotective effects.Herbals and their Effects on Human Health is an essential resource for food scientists, physicians, biomedical researchers, pharmacologists, and nutritionists seeking to deepen their understanding of how herbal and bioactive components influence health and wellness.

  • Insect Bioactives

    Innovations in Food, Feed, Pharma and Cosmetics
    • 1st Edition
    • Abdalbasit Adam Mariod + 2 more
    • English
    Insect Bioactives: Innovations in Food, Feed, Pharma and Cosmetics serves as a comprehensive resource for researchers and professionals seeking to harness the power of insects as sustainable bioactive sources and beneficial health and wellness solutions. The book identifies the nutritional and chemical composition of insects, presenting them as versatile ingredients for the development of functional foods, nutraceuticals, animal feed and cosmetics. By examining how edible insects can be reared on agri-food by-products and organic waste, this volume illustrates how feeding strategies can influence their nutritional and bioactive profiles. The text also addresses potential allergenic risks and consumer behavior insights, equipping readers with strategies to promote acceptance of insect-based products in the market.Structured into eight sections, Insect Bioactives: Innovations in Food, Feed, Pharma and Cosmetics covers a wide array of topics essential for understanding insect bioactives. From the foundational overview of insect-based compounds to their applications in functional foods, animal feed, pharmaceuticals, and cosmetics, each section provides insights into the health benefits and technological innovations associated with insect bioactives. The text also discusses regulatory considerations and features case studies that showcase successful applications in various industries.

  • Transesophageal Echocardiography

    Basic and Advanced Aspects and Clinical Field of Application
    • 1st Edition
    • Antonello D’Andrea
    • English
    Transesophageal Echocardiography: Basic and Advanced Aspects and Clinical Field of Application provides clinicians and echocardiography professionals with a thorough and practical resource covering both the fundamental principles and advanced clinical uses of TEE. It benefits the audience by delivering step-by-step guidance on image acquisition, interpretation of valve and ventricular pathology, and real-world applications in perioperative, emergency, and interventional settings. Richly illustrated and supplemented by instructional videos, the book’s contents include diagnostic techniques, perioperative management, assessment of prosthetic and congenital heart conditions, and specialized topics such as TEE in sports cardiology and critical care—empowering readers to improve patient outcomes and master the latest advancements in cardiovascular imaging.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • Chronic Kidney Disease Management Through Herbal Phytoceuticals

    Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management
    • 1st Edition
    • Kalicharan Sharma
    • English
    Chronic Kidney Disease Management Through Herbal Phytoceuticals: Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management examines chronic kidney disease (CKD) through the lens of plant-, marine-, and microbe-derived compounds. The field increasingly requires safer, non-invasive therapies that complement existing regimens while clarifying mechanisms of action. By combining ethnobotanical knowledge with contemporary computational methods, this work serves as a translational resource for researchers, clinicians, and students seeking evidence-based, mechanism-driven phytopharmaceutical approaches to nephroprotection and disease modification. Readers gain a framework for integrating traditional knowledge with modern drug discovery pipelines. The table of contents outlines a progression from foundational concepts to translational applications. Chapters 1–3 cover the global burden, pathophysiology, and current management of CKD. Chapter 4 identifies druggable molecular targets. Chapters 5–7 survey plant-based phytoceuticals for CKD management, marine natural products as emerging CKD therapies, and microbial-derived candidates as potential CKD agents, supported by efficacy and safety data. Chapters 8–9 apply molecular docking and docking-based mechanistic insights to plant, marine, and microbial compounds. Chapters 10–12 address clinically validated phytopharmaceuticals... formulation science, and global regulatory considerations. Chapter 13 presents clinical and preclinical case studies to illustrate practical applications. This book delivers clear benefits to end users by providing integrated, mechanism-driven insights that connect basic science to clinical decision-making. Readers gain access to curated data on plant-, marine-, and microbial-derived compounds along with their targets, efficacy, and safety, supported by docking-based mechanistic validation. It also addresses formulation challenges, regulatory pathways, and quality-control considerations essential for translating phytopharmaceuticals from bench to bedside, including safety assessment and scalable product development. This blend of theory and practical guidance supports researchers designing studies, clinicians implementing evidence-based phytotherapy, and educators teaching multidisciplinary approaches to CKD management across academic and clinical settings.

  • Cell Death Part G

    • 1st Edition
    • Volume 214
    • English

  • Advances in Virus Research

    • 1st Edition
    • Volume 127
    • English

  • Translational Insights in Regenerative Medicine

    • 1st Edition
    • Volume 228
    • English
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Animal Genomics

    • 2nd Edition
    • Sukanta Mondal + 1 more
    • English
    Advances in Animal Genomics, 2nd Edition offers a comprehensive exploration of the latest developments in animal genomics and biotechnology. This updated edition integrates traditional and cutting-edge omics approaches—including genomics, transcriptomics, epigenomics, and genome editing technologies—to advance sustainable livestock production and genetic improvement. Covering a wide range of topics from reproductive technologies, cloning, and stem cell applications to CRISPR/Cas9 genome editing, molecular markers, and nanobiotechnology, this volume delves into the molecular mechanisms underlying key traits such as yield, disease resistance, and stress tolerance. It also addresses emerging areas like microbial metagenomics, bioinformatics, gene therapy, and policy frameworks, providing readers with a holistic understanding of the scientific tools and ethical considerations shaping the future of animal biotechnology. Designed for scientists, researchers, students, educators, and professionals across agriculture, veterinary science, and biotechnology, Advances in Animal Genomics, 2nd Edition serves as an essential resource for those seeking to harness genomics for improving animal health, productivity, and sustainability. For those engaged in academic research, applied breeding programs, or policy development, this book offers the knowledge and insights needed to meet the global challenges of food security and environmental stewardship through innovative genomic solutions.

  • RNA-binding proteins Part B

    • 1st Edition
    • Volume 744
    • English

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 123
    • English
    This book provides the latest advances in the role of artificial intelligence in the precision nutrition and development of personalized foods, precision nutrition in autoimmune diseases, the need for vitamin D fortification in tropical regions, the health benefits of bioactive peptides, the factors affecting digestibility and glycemic index of rice, bio-based materials for intelligent sensing of food quality and safety, solid-state fermentation of cereal grains for modulating phenolic compounds, natural additives stabilized with nanoclays and the concomitant mycotoxin contamination in foods, especially on climate-related challenges for food safety.

  • Contemporary Challenges in Food Packaging

    Innovation, Consumer Acceptance, Sustainability, and Regulatory Considerations
    • 1st Edition
    • Sukvinder K. Jassi + 1 more
    • English
    Contemporary Challenges in Food Packaging: Innovation, Consumer Acceptance, Sustainability, and Regulatory Considerations is an essential resource for academic and industry professionals that explores the complexities of creating innovative, sustainable, safe packaging that attracts consumers within the context of sustainability. This comprehensive text examines the misunderstandings that lead not only consumers but also scientists and industry professionals, to question the necessity and sustainability of packaging materials without fully grasping their essential roles in environmental safety, food preservation, and effective packaging waste management. By highlighting the vital role packaging plays in consumer acceptance, and the circular economy, this book serves as a bridge between academic research and practical application, and gives readers the knowledge to navigate existing challenges in the field. Organized into seven sections,Contemporar... Challenges in Food Packaging: Innovation, Consumer Acceptance, Sustainability, and Regulatory Considerations features 19 chapters that cover everything from the historical evolution of food packaging to the latest innovations in smart packaging technologies. Readers will explore the implications of environmental sustainability, the adaptation to a circular economy model, and the emerging solutions for effective waste management. With contributions from leading experts, the text identifies best practices and innovative strategies that address regulatory requirements, and consumer and industry needs.

  • Precision Care in Gastroesophageal Reflux Disease

    Using Pathophysiology and Clinical Insights towards a Personalized Approach
    • 1st Edition
    • Walter W. Chan + 1 more
    • English
    Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approaches in managing GERD. This reference explores the evolving understanding of GERD pathophysiology and the necessity to move beyond generalized treatments toward disease phenotyping and targeted therapy. It emphasizes integrating clinical insights with emerging diagnostic technologies to optimize patient outcomes. The book’s content is organized into sections covering disease phenotypes and pathophysiology, clinical presentation, diagnostic techniques, and management approaches. Chapters include detailed discussions on symptom mechanisms, hypervigilance, diagnostic endoscopy, esophageal function testing, and both medical and surgical treatment options. Contributions from international experts provide evidence-based perspectives on utilizing scoring systems, ancillary tests, and adjunctive therapies to support precision care. Precision Care in Gastroesophageal Reflux Disease equips clinicians, advanced practice providers, and trainees with state-of-the-art knowledge to tailor evaluation and treatment strategies for diverse GERD phenotypes. It is an essential resource for those seeking to apply precision medicine principles in gastroenterology, enhancing diagnostic accuracy and therapeutic effectiveness in clinical practice.

  • Food Authentication and Future Challenges

    Ensuring Transparency in the Global Food Supply
    • 1st Edition
    • Shahzad Zafar Iqbal + 1 more
    • English
    Food Authentication and Future Challenges: Ensuring Transparency in the Global Food Supply explores the vital role of verifying food origin, content, and quality to prevent fraud, ensure safety, and meet regulatory standards. As globalization, climate change, and shifting consumer demands increase the complexity of food integrity, this book offers essential insights into current methods and emerging technologies for safeguarding our food supply. The book is divided into clear sections, covering foundational concepts, advanced identification techniques like chromatography, spectroscopy, DNA, and sensor-based methods, as well as specific challenges related to seafood, meat, honey, oils, herbs, and GMOs. It also highlights innovative solutions such as AI, machine learning, NGS, and CRISPR, and discusses key issues like climate impacts, ethical concerns, and policy enforcement. By combining scientific advances with future perspectives, this book provides a comprehensive resource for researchers, industry professionals, and policymakers committed to protecting food integrity in a rapidly changing world.

  • Neuroinflammation and Biomarker Discovery

    From Mechanisms to Clinical Application
    • 1st Edition
    • Arun Kumar Singh + 1 more
    • English
    Neuroinflammation and Biomarker Discovery: From Mechanisms to Clinical Application offers a detailed exploration of the molecular and cellular processes underlying neuroinflammatory conditions. This essential reference addresses the urgent need for advanced biomarkers that can facilitate early diagnosis, monitor disease progression, and guide personalized treatments in neurodegenerative and autoimmune disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The book synthesizes current knowledge on neuroimmune interactions, glial cell activation, blood-brain barrier integrity, and innate immune signaling pathways, providing a comprehensive framework for understanding neuroinflammatory mechanisms. It also covers state-of-the-art platforms for biomarker discovery, including transcriptomics, proteomics, lipidomics, epigenomics, extracellular vesicles, and neuroimaging techniques, emphasizing their translational potential. The inclusion of disease-specific biomarker landscapes enhances its relevance for clinicians and researchers working in diagnostics and drug development. The final sections focus on translational applications, such as clinical trial design, biomarker validation, and the integration of AI-driven multi-omics data for personalized neuroimmunology. This volume is an indispensable resource for neuroscientists, clinicians, graduate students, biotech professionals, and data scientists seeking to advance understanding and innovation in neuroinflammatory research and clinical practice. By bridging basic science and clinical application, it aims to accelerate the development of targeted therapies and diagnostic tools, ultimately improving patient outcomes in neuroinflammatory diseases

  • Understanding Mycotoxins

    Toxicity, Detection, Risk Assessment, and Prevention Strategies
    • 1st Edition
    • Vinay B. Raghavendra + 1 more
    • English
    Understanding Mycotoxins: Toxicity, Detection, Risk Assessment, and Prevention Strategies offers an in-depth exploration of their toxicological impact, detection techniques, and strategies for prevention and risk management. It addresses the critical health risks associated with mycotoxin exposure, including acute poisoning, carcinogenicity, and neurotoxicity, emphasizing the importance of accurate detection and effective mitigation measures. The book provides evidence-based insights into the mechanisms of mycotoxin toxicity, emerging threats, and the latest technological advances in analysis and detection. The book is structured into three detailed sections. The first section covers the fundamental aspects of mycotoxins, including their structures, biosynthetic pathways, sources of contamination, and health risks, supported by discussions on sampling, analytical techniques such as chromatography and spectroscopy, and the link between mycotoxins and diseases like cancer and neurological disorders. The second section delves into modern detection methods, highlighting advanced electrochemical sensors, immunoassays, biosensors, and innovative approaches utilizing machine learning, artificial intelligence, and nanotechnology for rapid and accurate identification of mycotoxins in various food matrices. The final section focuses on prevention and risk management, exploring detoxification strategies, mitigation techniques—including physical, chemical, biological, and emerging plasma and nanotechnology-based methods—and the regulatory frameworks that underpin safe food production and handling practices, aiming to reduce exposure and protect vulnerable populations globally.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 137
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1st Edition
    • Anand Krishnan + 3 more
    • English
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.

  • Omics Approaches in Rhizosphere Microbiology: Part B

    • 1st Edition
    • Volume 61
    • English
    Omics Approaches in Rhizosphere Microbiology: Part A offers a definitive, systems-level exploration of the complex microenvironment where plant roots and soil microorganisms interact. As global agriculture faces the dual challenges of climate change and food insecurity, understanding the rhizosphere has shifted from traditional culture-dependent isolation to advanced high-throughput molecular auditing. This volume serves as a comprehensive, technically rigorous manual and structural roadmap, bridging foundational rhizosphere biology with the cutting-edge structural analytical tools of modern polyphasic science.

  • Alternative Splicing

    Recent Advances in Health and Disease
    • 1st Edition
    • Sayeed ur Rehman A. Kalam + 1 more
    • English
    Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances, and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics.This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • The Vaccine Book

    New Insights, Approaches, and Technologies
    • 3rd Edition
    • Fabio Bagnoli + 2 more
    • English
    The Vaccine Book: New Insights, Approaches and Technologies, Third Edition provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. Edited by a new, highly experienced team of editors, the 3rd edition provides new approaches, design, and vaccine platform tools to develop vaccines quicker.This new edition is fully updated and designed for students, researchers, public health offcials, and all others interested in increasing their understanding of vaccines.

  • Innovation in Emergency Medicine

    Technology Development and Commercialization Handbook
    • 1st Edition
    • Nancy Patterson + 3 more
    • English
    Innovation in Emergency Medicine: Technology Development and Commercialization Handbook is a step-by-step guide to emergency medicine technology innovation reflecting recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads engineers, clinicians, students, researchers, and entrepreneurs through a clear process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. This new volume in the Clinical and Medical Innovation Series will be of interest to every biomedical engineer and those working in emergency medicine who has ever had a good idea for an invention but does not know where and how to start bringing it to the bedside.

  • Microplastics and the Hidden Threat to Human Reproduction

    Plastic Peril
    • 1st Edition
    • Nimra Afzal + 1 more
    • English
    Microplastics and the Hidden Threat to Human Reproduction: Plastic Peril explores the intricate relationship between microplastics and reproductive health, delving into the sources and distribution of microplastics in the environment, human exposure routes, associated risks, the toxicological effects on reproductive health, potential connections to fertility, endocrine disruption, and developmental consequences due to maternal exposure. It includes impacts on both male and female reproductive health, risks during pregnancy, population-level health concerns, strategies for mitigating microplastic exposure, and the policy and regulatory frameworks surrounding this issue. The book also provides insights into the future direction of research and public health initiatives.In essence, it explores how tiny microplastic particles can have significant and far-reaching consequences on human reproductive health, making this a vital and emerging area of concern. This is a comprehensive resource for anyone interested in understanding the various aspects of the microplastics-reprod... health connection and a go-to reference for researchers, healthcare professionals, policymakers, and concerned individuals.

  • Pharmaceutical QbD with Design of Experiments

    Statistical Tools and Applications in Drug Delivery Systems
    • 1st Edition
    • Khushwant Yadav
    • English
    Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

  • Melanin-Concentrating Hormone

    From Metabolism to Sleep Disorders
    • 1st Edition
    • Jackson C. Bittencourt + 1 more
    • English
    Melanin-Concentratin... Hormone: From Metabolism to Sleep Disorders, the latest volume in the Molecular Mediators in Health and Disease series, offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, along with the impact of MCH in psychiatric and neurodegenerative disorders and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behavior, sleep, cognition, memory, and peripheral function.The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. This is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology, and beyond.

  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1st Edition
    • Camilo N. Rodríguez + 6 more
    • English
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Tourette Syndrome and Other Tic Disorders

    • 1st Edition
    • Mariam Hull
    • English
    The Neuroscience of Tourette's Syndrome and Other Tic Disorders provides a foundation of the latest research into tic disorders and the brain, as well as including a comprehensive framework for the evaluation of tics. Authors across multiple specialties present the most thorough and latest knowledge of Tourette syndrome to include underlying pathophysiology, clinical presentation, how to differentiate it from other tic disorders, particularly functional tics. Clinical case studies will also feature throughout to outline challenging cases with expert commentary on evaluation and management strategies.

  • Introduction to Structural Bioinformatics

    • 1st Edition
    • Yang Zhang + 2 more
    • English
    Introduction to Structural Bioinformatics offers a complete overview on the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects, including bioinformatics databases, multiple sequence alignment, and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide on key principles, methods, and the most up-to-date developments across structural bioinformatics and computational structural biology. It will be a comprehensive reference for postgraduate students, instructors, and researchers working in these and adjacent subjects.

  • The Human Nervous System

    • 4th Edition
    • George Paxinos + 2 more
    • English
    The 4th Edition of the classic book The Human Nervous System continues to assemble contributions from world leaders in research on the brain, spinal cord and peripheral nervous system. This book has been edited by the best-known team of brain cartographers, and it has been completely revised to present the cutting edge of human neuroscience. The structure, connections and function are explained in depth, making this book essential to any student or scientist interested in brain anatomy and function.

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.

  • Practice-Based Physiology in Allied Health Sciences

    From Evidence to Clinical Application
    • 1st Edition
    • Satyajit Tripathy + 3 more
    • English
    Practice-Based Physiology in Allied Health Sciences: From Evidence to Clinical Application provides a comprehensive, systems-based exploration of human physiology specifically designed for applied health sciences. It moves beyond conventional textbook knowledge to integrate cardiovascular, respiratory, neurological, endocrine, and musculoskeletal systems within the context of real-world clinical and functional applications. By emphasizing translational physiology, the text helps readers understand how cellular and systemic mechanisms directly inform therapeutic assessment, intervention planning, and patient-centered care. The book’s multidisciplinary perspective supports students and practitioners in physiotherapy, occupational therapy, nursing, sports medicine, and behavioral science—highlighting physiology as a common language that unites diverse healthcare disciplines. Through detailed explanations, case studies, and applied scenarios, readers learn to interpret physiological data, identify dysfunctions, and design interventions grounded in scientific evidence. Ultimately, this resource bridges the gap between science and practice by linking physiological understanding to outcomes such as recovery, mobility, pain management, fatigue reduction, and overall well-being. It encourages critical thinking, clinical reasoning, and interprofessional collaboration—ensuri... that learners not only grasp how the human body functions but also how that knowledge can meaningfully improve health, performance, and quality of life.

  • Olive 4.0

    Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production
    • 1st Edition
    • Najla Trabelsi + 1 more
    • English
    Olive 4.0: Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production explores the revolutionary impact of Industry 4.0 technologies on the traditional olive sector. As olive farming and oil production face increasing pressures from labor shortages, resource constraints, and environmental concerns, this book addresses the urgent need for digital innovation tailored specifically to this industry. By focusing on cutting-edge tools such as the Internet of Things (IoT), Artificial Intelligence (AI), robotics, blockchain, and smart sensors, it highlights how these advances can enhance sustainability, productivity, and quality throughout the entire olive supply chain—from grove management to oil processing and distribution.Whether for smallholders seeking affordable solutions or large producers aiming for automation and traceability, the book delivers science-backed insights that promote eco-friendly practices while improving efficiency and reducing waste. Importantly, it also addresses challenges related to technology accessibility and equitable adoption, ensuring that innovations benefit a broad spectrum of stakeholders and support long-term sustainability goals.

  • Artificial Intelligence in Point-of-Care Nanobiosensors Technology

    Enhancing Disease Diagnostics and Improved Healthcare Outcomes
    • 1st Edition
    • Tharmaraj Vairaperumal + 2 more
    • English
    Artificial Intelligence in Point-of-Care Nanobiosensors Technology: Enhancing Disease Diagnostics and Improved Healthcare Outcomes delves into the revolutionary integration of artificial intelligence (AI) with nanobiosensors to elevate point-of-care (POC) diagnostics for both communicable and non-communicable diseases. Readers will find insightful chapters covering topics ranging from foundational AI and machine learning techniques to specific applications in cardiovascular disease, diabetes, cancer, chronic respiratory ailments, and infectious diseases. Each chapter not only highlights recent breakthroughs in nanobiosensors but also emphasizes the pivotal role of AI in enhancing diagnostic accuracy and facilitating personalized health interventions. Additional discussions around regulatory considerations and the future landscape of AI in biomedical research make this an essential read for those navigating this rapidly evolving field. This book primarily targets researchers and professionals engaged in the interdisciplinary realms of AI, nanomaterials, and biomedical sciences. By providing a critical understanding of emerging AI-based diagnostic technologies and their applications in POC settings, this book fosters collaboration across diverse scientific domains.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Animals and Human Society

    Impacts of Animals on People and People on Animals
    • 2nd Edition
    • Colin G. Scanes + 1 more
    • English
    Animals and Human Society: Impacts of Animals on People and People on Animals, Second editon provides a solid, scientific, research-based background to advance our understanding of how animals and humans interact and impact each other. Animals and humans have had profound effects on each other throughout human history, spanning all aspects of human society from agriculture, disease, culture, religion, companionship, entertainment, environment, and more. Developed by renowned experts Colin Scanes and Clive Phillips, this second edition features a new introductory chapter covering the biological concepts necessary for technical and non-technical audiences of this book. All first edition chapters have been revised to bring readers up to date on research advancements from the last decade, and novel chapters cover animal ethics, welfare, the basis of anthrozoology, zooarchaeology, and more. Guest essays further supplement updated chapter content by providing broad interdisciplinary and geographically diverse perspectives in the field. Animals and Human Society, Second Edition is an excellent resource for academics and industry professionals requiring fundamental information on the history and biology behind human-animal interactions, as well as interested laypersons looking to augment their knowledge on the many impacts of animals in human society.

  • Applications of Microfluidics Device Technology

    • 1st Edition
    • Volume 227
    • English
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

  • Electrocardiography of Laboratory Animals

    • 3rd Edition
    • Meg M. Sleeper + 1 more
    • English
    Electrocardiography of Laboratory Animals, Third Edition, provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book begins with the fundamental principles of electrocardiography and its applications in drug safety evaluation but then covers electrocardiography in a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees.Addition... it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. It is an essential resource for biological and medical researchers, veterinarians, zoologists, and students.

  • Geostatistical Approaches to Environmental and Public Health Issues

    • 1st Edition
    • Deepak Kumar + 4 more
    • English
    Geostatistical Approaches to Environmental and Public Health Issues discusses how geostatistical techniques can be leveraged to better understand and respond to pressing environmental and public health challenges. The book showcases how techniques like kriging, spatial regression, Bayesian modeling, and space-time analysis offer powerful, nuanced insights into these issues. Emphasizing stochastic, non-deterministic approaches, it highlights the importance of modeling uncertainty in both environmental and health domains. Through case studies and research-driven chapters, sections demonstrate how integrating geospatial and statistical methods can enhance our understanding of where, why, and how events occur—ultimately improving the precision of health interventions and environmental policies.By aligning cutting-edge statistical approaches with the geospatial dimensions of health and environmental data, this book fills a critical gap in the literature and supports more targeted, data-driven decision-making in the face of global uncertainty. It bridges methodological innovation with applied research, making it an essential resource for scientists, policymakers, and public health practitioners.

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