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Elsevier

Gynecological Disorders

From Pathophysiology to Translational and Precision Medicine

  • 1st Edition - June 1, 2027
  • Latest edition
  • Editors: Atar Singh Kushwah, Anurag Kumar Singh, Nitish Kumar Singh, Monisha Banerjee
  • Language: English

Integrates pathophysiology, clinical gynecology and translational science with precision medicine, molecular diagnostics, microbiome research, artificial intelligence and digital… Read more

Description

Integrates pathophysiology, clinical gynecology and translational science with precision medicine, molecular diagnostics, microbiome research, artificial intelligence and digital health

Gynecological Disorders: From Pathophysiology to Translational and Precision Medicine provides a multidisciplinary synthesis of major gynecological disorders and the scientific and technological advances transforming their diagnosis, management and prevention. Covering endometriosis, polycystic ovary syndrome, uterine fibroids, menstrual disorders and gynecological cancers, the book connects disease mechanisms and clinical challenges with emerging approaches in molecular biomarkers, liquid biopsy, microbiome science, artificial intelligence, digital health, regenerative medicine and nanomedicine.
Dedicated sections examine reproductive tract infections, HPV-associated carcinogenesis, antimicrobial resistance, environmental endocrine disruptors, mental health and the sociocultural determinants of gynecological health.
The volume also addresses clinical readiness, validation, health disparities, implementation science and health policy, distinguishing emerging scientific promise from real-world applicability.
Written for clinicians, researchers, trainees and public health professionals, the book integrates molecular, clinical, technological and population-health perspectives to provide a translational framework for understanding the evolving landscape of gynecological disorders and advancing equitable precision care.
  • Provides multidisciplinary coverage of major gynecological disorders by integrating pathophysiology, diagnosis, treatment, reproductive health, oncology and public health perspectives
  • Examines emerging approaches including molecular biomarkers and liquid biopsy, microbiome science, artificial intelligence, digital health, regenerative medicine and nanomedicine
  • Connects gynecological oncology, reproductive tract infections, HPV and antimicrobial resistance with advances in precision diagnosis, prevention and therapeutic strategies
  • Addresses health disparities, sociocultural determinants, mental health and implementation science to place biomedical advances within real-world healthcare systems and women’s health needs

Key features

  • Provides a multidisciplinary bench to bedside framework spanning clinical practice, research, and public health to improve care across gynecology, oncology, reproductive medicine, and women’s health
  • Presents in-depth coverage of emerging trends: AI-assisted diagnostics, personalized medicine, microbiome research, and digital health solutions
  • Includes practical tools, case studies, and implementation guides designed to accelerate evidence-to-practice translation
  • Includes online resources and learning materials to support ongoing education, collaboration, and policy-relevant decision-making

Readership

Gynecologists, Obstetricians, Reproductive Medicine Specialists, Gynecological Oncologists, and Women’s Health Clinicians and Researchers

Table of contents

Part I: Foundations and Current Burden

1. Global Epidemiology of Gynecological Disorders

2. Health Disparities and Access to Care

3. Sociocultural Determinants of Gynecological Health

Part II: Common Gynecological Disorders – Updates and Challenges

4. Endometriosis and Adenomyosis: Pathogenesis, Pain Phenotypes, and Emerging Therapies

5. Polycystic Ovary Syndrome (PCOS): Beyond the Reproductive Axis

6. Uterine Fibroids: Minimally Invasive Approaches and Molecular Targets

7. Menstrual Disorders: From Diagnosis to Management

Part III: Gynecological Oncology – Innovations and Interventions

8. Cervical Cancer: Screening, Vaccination, and Clinical Decision Pathways

9. Ovarian Cancer: Early Detection and Targeted Therapies

10. Endometrial Cancer and Obesity: A Growing Nexus

11. Molecular Biomarkers and Liquid Biopsies in Gynecological Cancers: Validation, Readiness, and Clinical Translation

Part IV: Reproductive Tract Infections and Microbiota

12. Vaginal Dysbiosis, STIs, and the Vaginal Microbiome

13. Human Papillomavirus (HPV) and Cervical Carcinogenesis

14. Emerging Infections and Antimicrobial Resistance

Part V: Emerging Technologies and Future Trends – Clinical Readiness and Translational Challenges

15. Artificial Intelligence and Imaging in Gynecology

16. Telemedicine and Mobile Health in Women’s Health

17. Fertility Preservation and Regenerative Medicine

18. Environmental Endocrine Disruptors and Gynecological Health

19. Nanomedicine in Gynecological Disorders: Current Advances and Future Directions

Part VI: Psychosocial and Public Health Perspectives

20. Mental Health in Gynecological Disorders

21.Gender-Based Violence and Gynecological Outcomes

22. Implementation Science and Health Policy for Women’s Health

Part VII: Concluding Perspectives and Future Directions

23. Concluding Synthesis and Future Directions in Gynecological Disorders

Product details

  • Edition: 1
  • Latest edition
  • Published: June 1, 2027
  • Language: English

About the editors

Atar Singh Kushwah

Editor
Dr. Atar Singh Kushwah is a molecular geneticist and translational oncologist whose work links genetics, epigenetics, and molecular oncology to women’s health and cancer outcomes. He earned a Ph.D. in Molecular and Human Genetics from Banaras Hindu University (in collaboration with the University of Lucknow), studying genetic and epigenetic changes in DNA repair and their impact on cervical cancer therapy. He conducted postdoctoral research at the Center for NanoBiotechnology Research, Alabama State University, and the Women’s Biomedical Research Institute at the Icahn School of Medicine at Mount Sinai, exploring how host genetics, metabolism, and tumor microenvironment signaling drive cancer progression and therapy resistance. Now an Assistant Professor at Manipal University Jaipur, his lab investigates the Microbiome–Epigenome–DNA Repair Axis as a determinant of gynecological disease susceptibility and treatment outcomes, including AI-driven diagnostics and CRISPR-based therapies. He has 30+ publications and serves on several editorial boards.
Affiliations and expertise
Assistant Professor, Manipal University Jaipur, Jaipur, India

Anurag Kumar Singh

Editor
Anurag Kumar Singh, PhD, is a Research Associate in the Department of Pharmaceutical Engineering and Technology at the Indian Institute of Technology (Banaras Hindu University), Varanasi, India. His research focuses on developing nanoparticulate systems for chronic pain, neurodegenerative disorders, brain-targeted drug delivery, diagnostics, and therapy. His work includes dendrimers, nanoporous silica and silicon materials, and polymeric nanoparticles for controlled drug delivery, with broader interests in nanomedicines for biomedical and healthcare applications and in integrating engineering, pharmaceutical, and medical research. He previously held postdoctoral research positions in cancer biology at Alabama State University, USA, and in nanotechnology and advanced materials at Bar-Ilan University, Israel.
Affiliations and expertise
Research Associate, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India

Nitish Kumar Singh

Editor
Dr. Nitish Kumar Singh is a Research Scientist-C at the Multidisciplinary Research Unit, IMS BHU, under Health Research–ICMR. He earned a PhD in Biochemistry from IMS-BHU, with work identifying MTHFR C677T and A1298C polymorphisms as major genetic risk factors for neural tube defects in North Indian populations, highlighting gene–environment interactions and the need for personalized prenatal care and targeted genomic screening. His broader interests include molecular genetics, cytogenetics, genomic medicine, and public health, focusing on genetic disorders, biomarker discovery, and translational diagnostics. He has expertise in Next-Generation Sequencing (GridION, Illumina MiSeq), Sanger sequencing, QF-PCR, microarrays, karyotyping, and bioinformatics. He has authored over 20 peer-reviewed articles and contributed to India’s SARS-CoV-2 genomic surveillance via GISAID. He is active in training, peer review, biomedical publishing, and academic mentorship.
Affiliations and expertise
Research Scientist, Multidisciplinary Research Unit, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

Monisha Banerjee

Editor
Dr. Monisha Banerjee is a Professor of Molecular and Human Genetics in the Department of Zoology at the University of Lucknow and the Founder-Director of the Institute of Advanced Molecular Genetics and Infectious Diseases. Her research focuses on genetic and epigenetic associations in type 2 diabetes, gestational diabetes, cervical cancer, and pulmonary diseases, emphasizing pharmacogenetics of antidiabetic and anticancer therapies and new treatment strategies. She mentors 31 PhD students and numerous postdocs, and has trained over 40 UG/PG students. Her team collaborates across medical universities and allied departments. She has led 14 major research projects and published around 200 papers; she has delivered invited talks, served as chair/panelist at conferences, and contributed to INDICO. Awards include SHIKSHAK SHREE (UP government) and the University of Lucknow Teacher Excellence Award. Former Dean of Research, Lucknow; life member of multiple academic societies.
Affiliations and expertise
Professor, Department of Zoology, University of Lucknow, Lucknow, India