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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Handbook of Reward and Decision Making

    • 1st Edition
    • Jean-Claude Dreher + 1 more
    • English
    This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders (schizophrenia, Parkinson's disease, drug addiction, pathological gambling, ...)

  • Mind and Motion: The Bidirectional Link between Thought and Action

    Progress in Brain Research
    • 1st Edition
    • Volume 174
    • Markus Raab + 2 more
    • English
    This volume investigates the implications of how our brain directs our movements on decision making. An extensive body of knowledge in chapters from international experts is presented as well as integrative group reports discussing new directions for future research.The understanding of how people make decisions is of central interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. For the first time the current volume provides a multidisciplinary overview of how action and cognition are integrated in the planning of and decisions about action.

  • Encyclopedia of Basic Epilepsy Research

    • 1st Edition
    • Philip A. Schwartzkroin
    • English
    As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy.

  • Neuromodulation

    • 1st Edition
    • Elliot S. Krames + 2 more
    • English
    Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices.All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come.

  • Encyclopedia of Neuroscience

    • 1st Edition
    • Larry R. Squire
    • English
    The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields. Arranged alphabetically by title, the articles encompass 10 volumes, making this the authoritative reference for the field.

  • Diffusion MRI

    From quantitative measurement to in-vivo neuroanatomy
    • 1st Edition
    • Heidi Johansen-Berg + 1 more
    • English
    Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments.The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder.

  • From Molecules to Networks

    An Introduction to Cellular and Molecular Neuroscience
    • 2nd Edition
    • Ruth Heidelberger + 3 more
    • English
    An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease.

  • Psychology of Learning and Motivation

    Moral Judgment and Decision Making
    • 1st Edition
    • Volume 50
    • English
    This volume presents a variety of perspectives from within and outside moral psychology. Recently there has been an explosion of research in moral psychology, but it is one of the subfields most in need of bridge-building, both within and across areas. Interests in moral phenomena have spawned several separate lines of research that appear to address similar concerns from a variety of perspectives. The contributions to this volume examine key theoretical and empirical issues these perspectives share that connect these issues with the broader base of theory and research in social and cognitive psychology. The first two chapters discuss the role of mental representation in moral judgment and reasoning. Sloman, Fernbach, and Ewing argue that causal models are the canonical representational medium underlying moral reasoning, and Mikhail offers an account that makes use of linguistic structures and implicates legal concepts. Bilz and Nadler follow with a discussion of the ways in which laws, which are typically construed in terms of affecting behavior, exert an influence on moral attitudes, cognition, and emotions. Baron and Ritov follow with a discussion of how people's moral cognition is often driven by law-like rules that forbid actions and suggest that value-driven judgment is relatively less concerned by the consequences of those actions than some normative standards would prescribe. Iliev et al. argue that moral cognition makes use of both rules and consequences, and review a number of laboratory studies that suggest that values influence what captures our attention, and that attention is a powerful determinant of judgment and preference. Ginges follows with a discussion of how these value-related processes influence cognition and behavior outside the laboratory, in high-stakes, real-world conflicts. Two subsequent chapters discuss further building blocks of moral cognition. Lapsley and Narvaez discuss the development of moral characters in children, and Reyna and Casillas offer a memory-based account of moral reasoning, backed up by developmental evidence. Their theoretical framework is also very relevant to the phenomena discussed in the Sloman et al., Baron and Ritov, and Iliev et al. chapters. The final three chapters are centrally focused on the interplay of hot and cold cognition. They examine the relationship between recent empirical findings in moral psychology and accounts that rely on concepts and distinctions borrowed from normative ethics and decision theory. Connolly and Hardman focus on bridge-building between contemporary discussions in the judgment and decision making and moral judgment literatures, offering several useful methodological and theoretical critiques. Ditto, Pizarro, and Tannenbaum argue that some forms of moral judgment that appear objective and absolute on the surface are, at bottom, more about motivated reasoning in service of some desired conclusion. Finally, Bauman and Skitka argue that moral relevance is in the eye of the perceiver and emphasize an empirical approach to identifying whether people perceive a given judgment as moral or non-moral. They describe a number of behavioral implications of people's reported perception that a judgment or choice is a moral one, and in doing so, they suggest that the way in which researchers carve out the moral domain a priori might be dubious.

  • Introduction to Quantitative EEG and Neurofeedback

    Advanced Theory and Applications
    • 2nd Edition
    • Thomas H. Budzynski + 3 more
    • English
    The study of Quantitative EEGs and Neurofeedback offer a window into brain physiology and function via computer and statistical analyses, suggesting innovative approaches to the improvement of attention, anxiety, mood and behavior. Resources for understanding what QEEG and Neurofeedback is, how they are used, and to what disorders and patients they can be applied are scarce, and this volume serves as an ideal tool for clinical researchers and practicing clinicians, providing a broad overview of the most interesting topics relating to the techniques. The revised coverage of advancements, new applications (e.g. Aspberger's, music therapy, LORETA, etc.), and combinations of prior approaches make the second edition a necessary companion to the first. The top scholars in the field have been enlisted and contributions will offer both the breadth needed for an introductory scholar and the depth desired by a clinical professional.

  • The Rhesus Monkey Brain in Stereotaxic Coordinates

    • 2nd Edition
    • George Paxinos + 3 more
    • English
    The Rhesus Monkey Brain in Stereotaxic Coordinates is the most comprehensive and accurate atlas of the monkey brain currently available. The second edition of this classic book is a complete revision, featuring many improvements and upgrades. Constructed by the established leaders in neuroanatomical atlas development, the new edition will again be the indispensable resource for all scientists working on the primate nervous system.

  • The Rat Brain in Stereotaxic Coordinates: Compact

    • 6th Edition
    • George Paxinos + 1 more
    • English
    The Rat Brain in Stereotaxic Coordinates, Compact Sixth Edition is a smaller sized (8.5 x11inch), abridged version of the most referenced work in neuroscience (over 35,000 citations for this atlas). The compact edition provides the coronal plates and diagrams of the current sixth edition in a smaller more convenient spiral format and at a student friendly price. This book includes an introduction for students to some of the major current concepts in neuroanatomy: neuromeres and brain development. Students and seasoned researchers will find herein the first major unified nomenclature ontology tree based on development. The atlas features 161 coronal photographic plates and 161 juxtaposed diagrams. The diagrams are in color, but the photographs are in black and white. The full-sized sixth edition is in full color and also features the sagittal and horizontal planes.

  • Chemoarchitectonic Atlas of the Rat Brain

    • 2nd Edition
    • George Paxinos
    • English
    Now in its 6th edition, the Paxinos and Watson The Rat Brain in Stereotaxic Coordinates has been the most used reference of neuroscientists for the past twentyfive years. Both the illustrations and nomenclature of the atlas have become standard tools used by almost all research neuroscientists who deal with anatomy, physiology, or function.In 1999, the same authors published volumes Chemoarchitectonic Atlas of the Rat Forebrain and Chemoarchitectonic Atlas of the Rat Brainstem. These publications have been recognized as providing an archive of chemical markers in the rat brain guiding researchers in the identification of structures in their own preparations in many areas of research. They provided primary data which researchers could apply to their own studies. These books were based on the 4th edition of the Rat Brain in Stereotaxic Coordinates, and are now out of print.This second edition of the material in these books will combine the two volumes of the first edition into a single volume. The photographs are presented one to a page in the forebrain and midbrain areas, two to a page in the hindbrain. Different chemoarchitectonic stains are displayed with labels identifying the structures of the brain, following the delineations and nomenclature of the Rat Brain in Stereotaxic Coordinates, Sixth Edition.

  • Stroke Part I: Basic and Epidemiological Aspects

    • 1st Edition
    • Volume 92
    • Marc Fisher
    • English
    This volume provides a vital and comprehensive resource on stroke, including research, diagnosis, prevention, and treatment modalities. Practitioners in these fields will find invaluable information in this handbook, from basic mechanisms of the disease, to enhanced diagnostic and therapeutic capabilities for patient care. With the field of cerebrovascular disorders, including stroke, making rapid advancements, clinicians will find illuminating and insightful chapters on the pathophysiological basis of this disorder. Advances in our understanding of the biochemical background of strokes, coupled with an examination of breakthroughs in epidemiology, genetics, neuroimaging, interventional radiology, surgery, and even clinical psychology are also explored, giving researchers and clinicians a profoundly altered way to approach stroke research, diagnosis, and patient treatment and care.

  • The Spinal Cord

    A Christopher and Dana Reeve Foundation Text and Atlas
    • 1st Edition
    • Charles Watson + 2 more
    • English
    Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN).

  • Stroke, Part II: Clinical Manifestations and Pathogenesis

    • 1st Edition
    • Volume 93
    • Marc Fisher
    • English
    This volume provides a comprehensive guide to the manifestations and pathogenesis involved with stroke, including advancements in research and a newfound understanding of the biochemical background of this cerebrovascular disorder. This intensive handbook is meant to give clinicians a source reference that will enable them to gain a thorough knowledge and understanding of the clinical features and management of the many neurological manifestations of stroke disorder. In addition, practitioners, clinicians, and researchers will gain a better understanding of highly studied topics, including amongst others, the medical complications associated with stroke, chapters on anterior circulation and hemorrhagic stroke syndromes, stroke related psychiatric disorders, and other rare causes of stroke disorder.

  • Stroke, Part III: Investigation and Management

    • 1st Edition
    • Volume 94
    • Marc Fisher
    • English
    This volume provides a comprehensive exploration of stroke, from basic mechanisms of disease to enhanced diagnostic and therapeutic capabilities. The ongoing efforts within the neurological community are also highlighted, bringing a better understanding of the pathophysiological basis of this disorder. Clinicians will find invaluable information that can be used to enhance the lives of an aging global population. Covered topics include the functional anatomy of the brain itself, as well as advancements in the understanding of the biochemical background of strokes. Related fields and their dramatic impact on stroke research are also included, with findings in the fields of epidemiology, genetics, neuroimaging, and interventional radiology thoroughly explored. In addition, great attention is paid to therapeutic avenues, including investigation, prevention, and patient management.

  • Neurogenic Inflammation in Health and Disease

    • 1st Edition
    • Volume 8
    • English
    Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain.

  • Glaucoma: An Open-Window to Neurodegeneration and Neuroprotection

    • 1st Edition
    • Volume 173
    • Carlo Nucci + 3 more
    • English
    Glaucoma is one of the main causes of blindness throughout the world. It is characterized by death of the retinal ganglion cells, which is associated with loss of the axons making up the optic nerve. Recent studies have demonstrated support for the classification of glaucoma as a degenerative disease of the central nervous system (CNS), leading researchers to look at identifying neuroprotection strategies for the treatment of this disease, like those used for other degenerative diseases of the CNS. This book will provide an in-depth examination of the most recent findings regarding glaucoma, including risk factors, diagnosis, clinical monitoring, treatment, and above all, the need for treatment based on the concept of neuroprotection. A large part of the book is devoted to research related to this new approach to the treatment of glaucoma.

  • MATLAB for Neuroscientists

    An Introduction to Scientific Computing in MATLAB
    • 1st Edition
    • Pascal Wallisch + 5 more
    • English
    MATLAB for Neuroscientists: An Introduction to Scientific Computing in MATLAB is the first comprehensive teaching resource and textbook for the teaching of MATLAB in the Neurosciences and in Psychology. MATLAB is unique in that it can be used to learn the entire empirical and experimental process, including stimulus generation, experimental control, data collection, data analysis and modeling. Thus a wide variety of computational problems can be addressed in a single programming environment. The idea is to empower advanced undergraduates and beginning graduate students by allowing them to design and implement their own analytical tools. As students advance in their research careers, they will have achieved the fluency required to understand and adapt more specialized tools as opposed to treating them as "black boxes". Virtually all computational approaches in the book are covered by using genuine experimental data that are either collected as part of the lab project or were collected in the labs of the authors, providing the casual student with the look and feel of real data. In some cases, published data from classical papers are used to illustrate important concepts, giving students a computational understanding of critically important research.

  • The Neurology of Consciousness

    Cognitive Neuroscience and Neuropathology
    • 1st Edition
    • Steven Laureys + 1 more
    • English
    Understanding consciousness is the major unsolved problem in biology. One increasingly important method of studying consciousness is to study disorders of consciousness, e.g. brain damage and disease states leading to vegetative states, coma, minimally conscious states, etc. Many of these studies are very much in the public eye because of their relationship to controversies about coma patients (e.g. Terry Schiavo case in the US recently), and the relationship to one of the major philosophical, sociological, political, and religious questions of humankind.This is the first book to summarize our current understanding of the neuroanatomical and functional underpinnings of human consciousness by emphasizing a lesional approach offered via the study of neurological patients. The selected contributors are all outstanding authors and undisputed leaders in their field.

  • Animal and Translational Models for CNS Drug Discovery: Neurological Disorders

    • 1st Edition
    • Robert A. McArthur + 1 more
    • English
    Neurological Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer’s disease, Parkinson’s disease, Huntington disease, ALS, and the epilepsies. Neurological Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the second volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually.

  • Concise Learning and Memory

    The Editor's Selection
    • 1st Edition
    • John H. Byrne
    • English
    The study of learning and memory is a central topic in neuroscience and psychology. Many of the basic research findings are directly applicable in the treatment of diseases and aging phenomena, and have found their way into educational theory and praxis.Concise Learning and Memory represents the best 30 chapters from Learning and Memory: A comprehensive reference (Academic Press March 2008), the most comprehensive source of information about learning and memory ever assembled, selected by one of the most respective scientists in the field, John H. Byrne. This concise version provides a truly authoritative collection of overview articles representing fundamental reviews of our knowledge of this central cognitive function of animal brains. It will be an affordable and accessible reference for scientists and students in all areas of neuroscience and psychology. There is no other single-volume reference with such authority and comprehensive coverage and depth currently available.

  • Serotonin-Dopamine Interaction: Experimental Evidence and Therapeutic Relevance

    • 1st Edition
    • Volume 172
    • Giuseppe Di Giovanni + 2 more
    • English
    This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson’s disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions.

  • Neuropsychologie du vieillissement normal et pathologique
    • 1st Edition
    • Kathy Dujardin + 1 more
    • French
    Dans nos sociétés modernes, le nombre de personnes âgées ne cesse de croître, et certaines d'entre elles voient leurs fonctions cognitives décliner au point de perdre leur autonomie physique, psychique et sociale. Élucider les mécanismes de ce déclin pour permettre un diagnostic précoce constitue un défi pour de nombreuses équipes de recherche. Fruit de la contribution de chercheurs et d'universitaires du monde francophone, cet ouvrage a pour objectif d'aborder le vieillissement cognitif normal et pathologique, à la fois sous l'angle des neurosciences et de la psychologie cognitive. Les premiers chapitres proposent une synthèse des éléments d'épidémiologie et de neurobiologie indispensables à la compréhension de l'évolution liée à l'âge des fonctions cérébrales. Une mise au point des connaissances actuelles en matière de vieillissement cognitif permet ensuite de mieux cerner l'impact du vieillissement sur les grandes fonctions cognitives, avant d'étudier les différentes pathologies du vieillissement s'accompagnant d'un déclin cognitif (maladie d'Alzheimer, démences vasculaires, démences frontotemporales, syndromes parkinsoniens). La notion de « mild cognitive impairment » (ou trouble cognitif léger) est largement développée à travers l'analyse d'études récentes. Cette approche est complétée par des procédures d'évaluation des fonctions cognitives ainsi que par des perspectives de traitement (pharmacologique, rééducation, …).

  • Epilepsy in Women

    The Scientific Basis for Clinical Management
    • 1st Edition
    • Volume 83
    • Barry Gidal + 1 more
    • English
    This volume guides the practitioner in the current management of women with epilepsy, in a comprehensive and scientifically informed manner. Many chapters are devoted to the various aspects of pregnancy management for women with epilepsy, from reducing the risks of medication exposure to breast feeding. All female age groups are discussed and chapters on issues important for adolescents and the mature women are also included. The editors have included internationally recognized experts as contributors, to bring together a body of knowledge unparalleled in previous settings. This book should be a guide to management for women with epilepsy for years to come, due to its solid scientific basis and the comprehensive vision of the contributors.

  • Puzzling Cases of Epilepsy

    • 2nd Edition
    • Dieter Schmidt + 1 more
    • English
    Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. Puzzling Cases of Epilepsy highlights the importance that original observations have in inspiring both new treatments and continued research.

  • Handbook of Episodic Memory

    • 1st Edition
    • Volume 18
    • Ekrem Dere + 3 more
    • English
    Episodic memory is the name of the kind of memory that records personal experiences instead of the mere remembering of impersonal facts and rules. This type of memory is extremely sensitive to ageing and disease so an understanding of the mechanisms of episodic memory might lead to the development of therapies suited to improve memory in some patient populations. Episodic memory is unique in that it includes an aspect of self-awareness and helps us to remember who we are in terms of what we did and what we have been passed through and what we should do in the future. This book brings together a renowned team of contributors from the fields of cognitive psychology, neuropsychology and behavioural and molecular neuroscience. It provides a detailed and comprehensive overview of recent developments in understanding human episodic memory and animal episodic-like memory in terms of concepts, methods, mechanisms, neurobiology and pathology. The work presented within this book will have a profound effect on the direction that future research in this topic will take.

  • The Prefrontal Cortex

    • 4th Edition
    • Joaquin Fuster
    • Joaquin Fuster
    • English
    This is the fourth edition of the undisputed classic on the prefrontal cortex, the principal "executive" structure of the brain. Because of its role in such cognitive functions as working memory, planning, and decision-making, the prefrontal cortex is critically involved in the organization of behavior, language, and reasoning. Prefrontal dysfunction lies at the foundation of several psychotic and neurodegenerative disorders, including schizophrenia and dementia.

  • Using Eye Movements as an Experimental Probe of Brain Function

    A Symposium in Honor of Jean Büttner-Ennever
    • 1st Edition
    • Volume 171
    • R. John Leigh + 1 more
    • English
    This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor Professor Jean Büttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological, pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus, and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments for nystagmus and motion sickness.

  • Quantitative EEG, Event-Related Potentials and Neurotherapy

    • 1st Edition
    • Juri D. Kropotov
    • English
    While the brain is ruled to a large extent by chemical neurotransmitters, it is also a bioelectric organ. The collective study of Quantitative ElectroEncephaloGrap... (QEEG-the conversion of brainwaves to digital form to allow for comparison between neurologically normative and dysfunctional individuals), Event Related Potentials (ERPs - electrophysiological response to stimulus) and Neurotherapy (the process of actually retraining brain processes to) offers a window into brain physiology and function via computer and statistical analyses of traditional EEG patterns, suggesting innovative approaches to the improvement of attention, anxiety, mood and behavior.The volume provides detailed description of the various EEG rhythms and ERPs, the conventional analytic methods such as spectral analysis, and the emerging method utilizing QEEG and ERPs. This research is then related back to practice and all existing approaches in the field of Neurotherapy - conventional EEG-based neurofeedback, brain-computer interface, transcranial Direct Current Stimulation, and Transcranial Magnetic Stimulation - are covered in full. While it does not offer the breadth provided by an edited work, this volume does provide a level of depth and detail that a single author can deliver, as well as giving readers insight into the personl theories of one of the preeminent leaders in the field.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 38
    • H. Jane Brockmann + 5 more
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect — full-text online from volume 30 onward.

  • Human Learning: Biology, Brain, and Neuroscience

    • 1st Edition
    • Volume 139
    • Aaron S. Benjamin + 3 more
    • English
    Human learning is studied in a variety of ways. Motor learning is often studied separately from verbal learning. Studies may delve into anatomy vs function, may view behavioral outcomes or look discretely at the molecular and cellular level of learning. All have merit but they are dispersed across a wide literature and rarely are the findings integrated and synthesized in a meaningful way. Human Learning: Biology, Brain, and Neuroscience synthesizes findings across these levels and types of learning and memory investigation.Divide... into three sections, each section includes a discussion by the editors integrating themes and ideas that emerge across the chapters within each section. Section 1 discusses general topics in human learning and cognition research, including inhibition, short term and long term memory, verbal memory, memory disruption, and scheduling and learning. Section 2 discusses cognitive neuroscience aspects of human learning. Coverage here includes models, skill acquisition, declarative and non declarative memory, age effects on memory, and memory for emotional events. Section 3 focuses on human motor learning.This book is suitable for cognitive neuroscientists, cognitive psychologists, kinesthesiologists, and graduate courses in learning.

  • Handbook of Cognitive Science

    An Embodied Approach
    • 1st Edition
    • Paco Calvo + 1 more
    • English
    The Handbook of Cognitive Science provides an overview of recent developments in cognition research, relying upon non-classical approaches. Cognition is explained as the continuous interplay between brain, body, and environment, without relying on classical notions of computations and representation to explain cognition. The handbook serves as a valuable companion for readers interested in foundational aspects of cognitive science, and neuroscience and the philosophy of mind. The handbook begins with an introduction to embodied cognitive science, and then breaks up the chapters into separate sections on conceptual issues, formal approaches, embodiment in perception and action, embodiment from an artificial perspective, embodied meaning, and emotion and consciousness. Contributors to the book represent research overviews from around the globe including the US, UK, Spain, Germany, Switzerland, France, Sweden, and the Netherlands.

  • Animal Models in Eye Research

    • 1st Edition
    • Panagiotis Antonios Tsonis
    • English
    The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease.

  • Neuromuscular Junction Disorders

    • 1st Edition
    • Volume 91
    • A. G. Engel
    • English
    This volume provides concise and comprehensive information on neuromuscular disorders, including rapid advancements in the understanding of the neurobiology of neuromuscular transmission. In addition, clinicians will find timely discussions on the various forms of these disorders that have been discovered due to increased study within the field. New observations into the immunopathogenesis of myasthenia gravis, and the molecular mechanisms underlying the links between activity and patterns of gene expression, particularly in muscle, are also explored, along with novel information on the understanding of the pathophysiology of the heterogeneous group of peripheral nerve hyperexcitability syndromes. Each of these valuable insights, and their accompanying explanations, provides a framework on which new therapeutic strategies can be built to aid in the enhancement and restoration of normal function in neuromuscular junction disorders.

  • Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease

    • 1st Edition
    • Volume 170
    • Rainer Landgraf + 1 more
    • English
    Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohyp... system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike.

  • Neurobiology of the Parental Brain

    • 1st Edition
    • Robert Bridges
    • English
    This book presents cutting edge research on the basic neurobiology of parental behavior as it relates to behavioral disorders, including postpartum depression, anxiety, and inadequate parental bonding to infants. Internationally recognized basic and clinical researchers present new research findings in humans and animals that elucidate the roles of the brain, physiological state, genes and environment in maternal and paternal care. By bridging the gap between basic and clinical research, new understandings of how the biology of the brain and the reproductive state of the parent impact their mental health and the successful rearing of young emerge.

  • The Hypothalamus-Pituitary-Adrenal Axis

    • 1st Edition
    • Volume 7
    • English
    The hypothalamic-pituita... axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease.

  • Psychiatric Controversies in Epilepsy

    • 1st Edition
    • Andres Kanner + 1 more
    • English
    Psychiatric Controversies in Epilepsy addresses controversial clinical issues of the psychiatric aspects of epilepsy. The book explores the reasons behind the poor communication between psychiatrists and neurologists and suggests potential remedies to this important problem, and two chapters are devoted to examining whether psychiatrists and neurologists are properly trained to recognize and treat conditions that both disciplines commonly encounter in clinical practice. Identification of the causes behind the high rate of comorbidity between epilepsy and mood, anxiety, psychotic and attention deficit disorders is given high priority in the volume, and a specific review of the evidence of common pathogenic mechanisms that may be operant in epilepsy and these psychiatric disorders is included. Recently identified bidirectional relationship between mood disorders and epilepsy and its implication in the course and response to treatment of the seizure disorder are also explored. Several chapters are devoted to rectify common misunderstandings of the use of psychotropic drugs in patients with epilepsy, including the use of antidepressant and central nervous system stimulants. Finally, one chapter explores the possibility of organic causes of psychogenic non-epileptic seizures.

  • Mathematical Difficulties

    Psychology and Intervention
    • 1st Edition
    • English
    This book examines the mathematical difficulties in typical and atypical populations. It discusses the behavioural, educational and neuropsychological characteristics of people with mathematical difficulties, and educational interventions to prevent, diagnose, treat or ameliorate such difficulties. The book brings together studies from different disciplines, including developmental psychology, neuroscience and education, and includes perspectives from practicing teachers.The book is divided into three major sections. The first includes chapters about the nature and characteristics of mathematical difficulties in the population as a whole, in relation to both psychology and education. The second deals with mathematical difficulties in children with other problems such as specific language impairment and dyslexia. The third discusses methods of interventions aimed at preventing, treating or ameliorating mathematical difficulties, and will include discussions of assessment and diagnosis.

  • Dementias

    • 1st Edition
    • Volume 89
    • Charles Duyckaerts + 1 more
    • English
    This volume provides a comprehensive understanding of the biology of dementias, including information on advancements in the way these disorders are perceived and studied. From earlier assumptions that cognitive deficits were simply age related, this handbook progresses into complex discussions of the diseases that affect the cortex of the human brain. Clinicians will find extensive diagnostic and research perspectives on a variety of interesting topics, including neuropathology, physiopathology, biology, clinics, and imaging information on all, or most, of the dementing disorders currently known. In addition, chapters devoted to legal and ethical issues give practitioners and health care workers an informative view on complex dementias and the way these disorders affect patients and families. Clinicians in all levels of expertise will find useful and synthetic information.

  • Disorders of Consciousness

    • 1st Edition
    • Volume 90
    • G. Bryan Young + 1 more
    • English
    This volume encompasses a variety of topics pertaining to patients with altered levels of consciousness, including valuable differences between disorders. Neurologists, researchers, and clinicians will find a comprehensive accounting of the distinctions between disorders that cause these altered states. Beginning with basic concepts of consciousness and neurobiology, this handbook progresses into more targeted and complex areas of discussion, including important technological advancements that have occurred in neuroimaging. Neurologists who are frequently called upon for prognostication and to guide management of patients with these disorders will find invaluable information, including chapters discussing comatose states in children and pregnant women, encephalopathic patients, nutrition disorders, and vegetative and minimally conscious states. In addition, chapters devoted to philosophical backgrounds and ethical implications involving patients with impaired consciousness, are thoroughly presented.

  • The Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1st Edition
    • Volume 49
    • English
    The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Volume 49 contains chapters on short-term memory, theory and measurement of working memory capacity limits, development of perceptual grouping in infancy, co-constructing conceptual domains through family conversations and activities, the concrete substrates of abstract rule use, ambiguity, accessibility, and a division of labor for communicative success, and lexical expertise and reading skill.

  • Handbook of Motivation and Cognition Across Cultures

    • 1st Edition
    • Richard Sorrentino + 1 more
    • English
    In recent years there has been a wealth of new research in cognition, particularly in relation to supporting theoretical constructs about how cognitions are formed, processed, reinforced, and how they then affect behavior. Many of these theories have arisen and been tested in geographic isolation. It remains to be seen whether theories that purport to describe cognition in one culture will equally prove true in other cultures. The Handbook of Motivation and Cognition Across Cultures is the first book to look at these theories specifically with culture in mind. The book investigates universal truths about motivation and cognition across culture, relative to theories and findings indicating cultural differences. Coverage includes the most widely cited researchers in cognition and their theories- as seen through the looking glass of culture. The chapters include self-regulation by Tory Higgins, unconscious thought by John Bargh, attribution theory by Bernie Weiner, and self-verification by Bill Swann, among others. The book additionally includes some of the best new researchers in cross-cultural psychology, with contributors from Germany, New Zealand, Japan, Hong Kong, and Australia. In the future, culture may be the litmus test of a theory before it is accepted, and this book brings this question to the forefront of cognition research.

  • Neurologie du comportement

    La dimension neurologique de la neuropsychologie
    • 1st Edition
    • Armin Schnider
    • French
    À la confluence de la neurologie, de la neuropsychologie et de la psychiatrie, la neurologie comportementale est une spécialité qui s'intéresse aux troubles cognitifs, émotionnels et comportementaux dus à des atteintes cérébrales. Elle explore les mécanismes, la base anatomique et les étiologies des dysfonctionnements des fonctions supérieures du cerveau, telles que la mémoire, le langage, la pensée spatiale et le raisonnement. Conçu dans une approche clinique, cet ouvrage constitue une introduction approfondie à la neurologie du comportement. Après un rappel des bases anatomiques du cerveau, chaque chapitre traite successivement des principaux troubles : • État confusionnel et troubles de l'attention • Syndromes frontaux • Aphasies et syndromes apparentés • Troubles du traitement spatial • Agnosies • Troubles mnésiques • Syndromes calleux • Démences Ces troubles sont d'abord définis, puis passés au crible de l'analyse anatomoclinique afin d'en examiner les causes et l'évolution. Pour chacune de ces pathologies, les techniques d'évaluation sont détaillées en fonction du contexte clinique. Aussi, cet ouvrage présente un réel intérêt pratique et pédagogique à travers l'étude de nombreux cas cliniques, des propositions de tests adaptés, et de multiples schémas anatomiques et tableaux récapitulatifs.

  • Cytokines and the Brain

    • 1st Edition
    • Volume 6
    • English
    This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment.

  • Essence of Memory

    • 1st Edition
    • Volume 169
    • Wayne S. Sossin + 3 more
    • English
    This selection of reviews gives an up-to-date picture of memory research. Great progress has been made in identifying the memory trace at the molecular and cellular level and individual reviews address the major mechanisms by which changes in synaptic strength can persist. Exciting research at the systems level is also reviewed including the growing importance of changes in inhibitory interneurons and how they play a role in memory formation. Finally, reviews present cognitive and neurobiological models of human memory that explain, characterize and organize the act of memory within a coherent framework.

  • Neuropsychology and Behavioral Neurology

    • 1st Edition
    • Volume 88
    • Georg Goldenberg + 1 more
    • English
    This volume presents a comprehensive guide to one of the most important goals of neuroscience, establishing precision structure-function relationships in the brain. Progressing from the early stages of research, specifically the advent of computerized tomography and later, magnetic resonance imaging, this invaluable resource will take clinicians on an all encompassing journey into the ways different fields of neurology can work together to advance our understanding of brain disorders. Complex topics including the neurochemistry of cognition, neuropsychology of aging and dementia, disorders of semantic memory, working memory, and the dysexecutive syndromes, amongst others, are thoroughly discussed and presented. Clinicians will find a state-of-the-art reference guide that can be used to further understand how the fields of neuropsychology and behavioral neurology can complement each other to produce advancements in the neurosciences.

  • Atlas of the Developing Rat Nervous System

    • 3rd Edition
    • Ken Ashwell
    • English
    The Atlas of the Developing Rat Nervous System, 3rd edition builds on the many excellent features of the second edition by increasing the number of ages represented and by the inclusion of colour plates. The third edition now contains over 20% more plates with the added material depicting early ages not well covered in earlier editions and yet is presented in a concise easy-to-use format. The Atlas provide the most comprehensive depiction not just of structures in the brain and spinal cord but also of peripheral nervous system elements and their target organs that are important for developmental neurobiologists. This allows the user to follow seamlessly neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in the third edition has been thoroughly updated to ensure accuracy and compatibility with modern developmental biology findings and terminology.

  • The Limits of Dream

    A Scientific Exploration of the Mind / Brain Interface
    • 1st Edition
    • J. F. Pagel
    • English
    Approx.250 pages

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