LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This is followed by a selection of ho… Read more
LIMITED OFFER
Immediately download your ebook while waiting for your print delivery. No promo code needed.
This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This is followed by a selection of hot topics in pathophysiological research, from molecular studies to system-level investigations based on in vivo electrophysiological recordings and neurocomputational methods.
Section I: Genetic and molecular mechanisms of neurodegeneration in PD
1
Identifying PD-causing genes and genetic susceptibility factors: current approaches and future prospects
Thomas Gasser
2
The impact of genetic research on our understanding of Parkinson's Disease
Ted Dawson
Ian Martin, Valina L. Dawson
3
Unraveling the role of defective genes
Mark Cookson
4
What causes the death of dopaminergic neurons in Parkinson’s disease?
James Surmeier
Jaime N. Guzman, Javier Sanchez-Padilla and Joshua Goldberg
5
Intracellular Signaling Pathways In Dopamine Cell Death And Axonal Degeneration
Robert Burke
6
Control of mitochondrial integrity in Parkinson’s Disease
Serge Przedborski
Cristofol Vives-Bauza, Maja Tocilescu, Rosa L. A. deVries, Dana M. Alessi, Vernice Jackson-Lewis
7
Role of Post-Translational Modifications in Modulating the Structure, Function and Toxicity of α-synuclein: Implications for Parkinson’s Disease Pathogenesis and Therapies
Hilal Lashuel
Abid Oueslati, Margot Fournier
Section II: Cellular and system-level pathophysiology of the basal ganglia in PD
8
The role of dopamine in modulating the structure and function of striatal circuits
James Surmeier
Weixing Shen, Michelle Day, Tracy Gertler, Savio Chan, Xianyong Tian and Joshua L. Plotkin
9
Assemblies of glutamate receptor subunits with post-synaptic density proteins and their alterations in Parkinson’s disease
Monica Di Luca
Paolo Calabresi
10
Adenosine-dopamine interactions
Micaela Morelli
Anna R Carta, Anil Kachroo, Michael A. Schwarzschild
11
Maladaptive plasticity in L-DOPA-induced dyskinesia
M. Angela Cenci
Christine Konradi
12
Effects of GPi and STN inactivation on physiological, motor, cognitive
and motivational processes in animal models of Parkinson's disease
Chistelle Baunez
Paolo Gubellini
13
Computational physiology of the basal ganglia in Parkinson’s disease
Hagai Bergman
Michal Rivlin-Etzion, Shlomo Elias, Gali Heimer
14
Neurocomputational models of motor and cognitive
deficits in Parkinson's Disease
Michael J. Frank
Thomas V. Wiecki
AB
AC