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Books in Life sciences

  • Human Microbiome and their Implications for Oncological Diagnosis and Treatment

    A Handbook for Clinicians and Researchers
    • 1st Edition
    • Mohammad Akram
    • English
    Human Microbiome and their Implications for Oncological Diagnosis and Treatment; A Handbook for Clinicians and Researchers explores the crucial role of the human microbiome in oncology. The book aims to provide a thorough understanding of microbiome-oncology interactions by compiling diverse perspectives and insights into existing research findings and methodologies. It addresses the need for a comprehensive educational resource tailored to the needs of clinicians and researchers. Contributed by leading experts, it examines the multifaceted roles, diagnostic potential, and therapeutic implications of the microbiome in cancer.Readers will find an in-depth look at microbiome-oncology interactions, addressing microbial dysbiosis, diagnostic biomarkers, therapeutic interventions, and emerging research trends. The handbook provides practical insights, clinical guidelines, and fosters interdisciplinary collaboration to advance the field of oncology to clinicians, researchers, educators, and students seeking up-to-date information on the role of the human microbiome in cancer.

  • Neurological Assessment Made Easy

    A Step-by-Step Guide for Physiotherapists
    • 1st Edition
    • Vishal Verma
    • English
    Neurological Assessment Made Easy: A Step-by-Step Guide for Physiotherapists delves into the intricacies of neurological assessment, covering a wide range of topics such as sensory and motor function, reflexes, coordination, balance, and cognition. This text provides physiotherapists and clinicians with a comprehensive framework to systematically assess and evaluate the neurological status of their patients. This book provides practical strategies and tips to navigate challenges effectively, ensuring accurate and meaningful assessment results and emphasizes the importance of effective neurological assessment in guiding the development of personalized treatment plans.

  • Mastering Supraventricular Tachycardia Diagnostics in the Electrophysiology Lab

    • 1st Edition
    • Konstantinos P. Letsas
    • English
    Mastering Supraventricular Tachycardia Diagnostics in the Electrophysiology Lab is dedicated to the diagnostics of supraventricular tachycardias (SVTs) for the electrophysiologist. The book is organized as a flowchart, allowing readers to accurately determine the proper next steps to take when managing patients' presenting symptoms. Its diagnostic approach starts with the evaluation of the 12-lead ECG, continues with electrophysiological observations and maneuvers, and ends with three-dimensional mapping techniques and real-life cases. Chapters are concise and focus on demonstrating the background of each maneuver in a simple manner by using sketches and electrograms from the lab.Each chapter contains a brief summary of when to use a maneuver, how to perform it, what to expect as responses to the maneuver, and interpretation of possible responses. Final chapters discuss real-life cases where the aforementioned diagnostic approaches are adapted to conditions that may not be ideal (for example, non sustained tachycardias). The book provides a start to finish explication of how to comprehend, diagnose, and manage all aspects of SVT.

  • ​​Abdominal Pain

    Essentials of Pathophysiology and Treatment
    • 1st Edition
    • Jakub Fichna
    • English
    Abdominal Pain: Essentials of Pathophysiology Treatment is the most up-to-date and comprehensive resource on abdominal pain. The book highlights new biomarkers, targets, and diagnostic techniques that are shaping the future of abdominal pain management, ensuring readers absorb the latest trends in diagnosis and treatment. By covering abdominal pain in the context of various specialties, it ensures a multidisciplinary understanding of these conditions for developing effective treatment strategies and improving patient outcomes. This first of its kind resource focuses on abdominal pain across numerous specialties, eliminating the need to search for information from innumerable sources.It is designed for researchers, clinicians, and students, providing an unparalleled depth of knowledge and insights into the diagnosis and treatment of abdominal pain. Expert contributors, selected for their specialized knowledge, bring the latest publications, advances, and cutting-edge research to ensure the most current information available. This innovative approach compiles diverse aspects of abdominal pain, offering insights into pathophysiology, molecular pathways, and potential cross-talks. Whether you are a seasoned clinician, a researcher, or a medical student, this guide will provide you with the most current and comprehensive information available, helping you stay at the forefront of abdominal pain diagnosis and treatment.

  • Systemic Lupus Erythematosus

    Basic, Applied and Clinical Aspects
    • 3rd Edition
    • George C. Tsokos
    • English
    Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects has been an essential resource for scientists and clinicians in this field since its original publication in 2015. The third edition of this work has been completely updated and expanded with the latest scientific and clinical developments in Systemic Lupus Erythematosus (SLE) to date. Contributors at the forefront of each topic come together to enhance content on epidemiology and diagnosis, pathogenesis, mechanisms of tissue damage, clinical aspects of the disease, antiphospholipid syndrome, and treatments. Also added is the latest information on new treatments, criteria, monogenic forms of lupus, insights on the role of microbiome, and advances in understanding disease pathogenesis. This must-have reference is an indispensable resource for specialists in the diagnosis and management of patients with SLE as well as early career or experienced investigators studying basic aspects of the disease. It is a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a key reference work for hospital libraries.

  • Textbook of Nephro-Endocrinology

    • 3rd Edition
    • Ajay K. Singh + 1 more
    • English
    Textbook of Nephro-Endocrinology... Third Edition remains the definitive translational reference in the field of nephroendocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. This new edition includes updates on the pathophysiology of inflammation, iron metabolism and erythropoiesis, mineralocorticoid receptor antagonists, the treatment of pre-eclampsia, and HIF-PHIs. The book offers researchers and clinicians expert analyses of nephroendocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism.S... the publication of the 2nd edition in 2009, many updates and new findings have emerged.

  • Gene Therapy in Neurodegenerative Disorders

    From Bench to Bedside
    • 1st Edition
    • Vahid Mansouri + 1 more
    • English
    Gene Therapy in Neurodegenerative Disorders: From Bench to Bedside offers a comprehensive review of gene therapy modalities and their applications in treating neurodegenerative disorders. Initial chapters focus on the fundamentals of gene therapy strategies, including gene delivery methods and CNS-targeted gene delivery. Subsequent chapters delve into specific neurodegenerative disorders such as Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), and Alzheimer's Disease (AD), highlighting the latest gene therapy approaches for each condition. Each chapter provides a detailed introduction to the relevant field before exploring specific tools and applications.With contributions from leading experts, the book addresses current and ongoing clinical trials, potential challenges, and promising advances in gene therapy for neurodegenerative disorders. It also discusses regulatory and ethical considerations in translating research from bench to bedside. This book is an essential resource for basic science researchers in gene therapy, geneticists, biotechnologists, and clinical researchers seeking new and effective treatments for neurodegenerative diseases. It equips readers with the knowledge and tools needed to advance their work and drive innovation in gene therapy.

  • Starch-Based Materials

    Principles and Applications
    • 1st Edition
    • Ming Miao + 1 more
    • English
    Starch-Based Materials: Principles and Applications explores the cutting-edge research and development of starches as biodegradable, renewable biomaterials addressing urgent environmental concerns associated with non-biodegradable polymers. This comprehensive volume delves into the structural characteristics of starches, recent advances in their physical, chemical, and enzymatic modifications, and emerging technologies that expand their use beyond traditional food applications. It highlights innovative approaches to enhance nutritional value and health benefits, including the design of gluten-free products and specialized foods, while also covering industrial uses such as hydrogels and controlled release systems. Despite extensive prior research on starch packaging and non-food uses, there is a significant gap in current literature regarding modern starch modifications and their multifunctional applications across food, pharmaceutical, medical, and biomaterial fields. This book addresses this gap by providing a timely, authoritative summary of recent scientific findings, aiming to stimulate innovation and sustainable development in starch utilization. It is an essential reference, particularly in courses related to food chemistry, food analysis, nutrition, packaging, pharmaceutical applications, and specialized medical fields such as controlled release technologies.

  • Kinase Targets and Drug Discovery

    • 1st Edition
    • Xiaoyun Lu
    • English
    Kinase Targets and Drug Discovery covers the critical role of kinases as regulators of cellular functions and their implications in a range of diseases, from cancers to cardiovascular disorders and inflammatory conditions. Readers will explore foundational concepts on the functions of kinases, the role of kinase inhibitors in disease therapy, and challenges faced. The second section focuses on innovative strategies in kinase drug discovery, covering screening and computational approaches, along with the development of covalent, macrocyclic, allosteric inhibitors, and kinase degraders. Final sections examine clinical applications, detailing how kinase inhibition can be harnessed for cancer therapies, non-oncologic diseases, and even non-catalytic functions.This book will serve as an indispensable resource for pharmacologists, medicinal chemists, and researchers in both academia and industry. By bridging the gap between foundational research and clinical application, it equips professionals with the latest insights and practical approaches to advance their understanding to contribute meaningfully to the evolving landscape of drug discovery.

  • Deep Learning Assessment of Neurological Imaging

    • 1st Edition
    • Tripti Goel + 3 more
    • English
    Deep Learning Assessment of Neurological Imaging provides an introduction to deep learning structures and pre-processing methods for detecting MRI anomalies. It also provides a comprehensive account of deep learning research on MRI images for Alzheimer's disease, Parkinson's disease, and schizophrenia, and a discussion on current research issues and future objectives. The book is a valuable resource to guide new entrants in the field to make a meaningful impact in their development efforts. The book concludes with a brief overview of the problems discussed and potential future advancements in the field.

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