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African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance

Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance

  • 1st Edition, Volume 115 - March 3, 2025
  • Latest edition
  • Editors: Victor Kuete, Jean-Pierre Jacquot
  • Language: English

African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part 3. Potential Pharmaceuticals to Overcome Cancers and their Ch… Read more

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Description

African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance offers detailed information on the best cytotoxic phytoconstituents of African medicinal plants that could be useful for the development of efficient pharmaceuticals that could be further explored to efficiently overcome cancers and their drug resistance. The book identifies and comments on the various classes of cytotoxic African secondary metabolites. The book also clearly identifies and comments on the best cytotoxic molecules identified in African medicinal plants. The book appears an amazing tool for Scientists to have state-of-the-art of the best cytotoxic phytoconstituents from the African flora, and to boost their clinical investigations.

Key features

  • Identifies the groups and classes of cytotoxic agents from African plants
  • A unique tool pooling together the best of African phytoconstituents with amazing potential toward various cancer cell lines, including the multidrug-resistant phenotypes
  • Discusses the various biosynthetic pathways of the classes of cytotoxic agents from African plants

Readership

Research scientists, Students, Herbalists, Pharmaceutical industries, General public, University libraries

Table of contents

1. Terpenoids, steroids, and saponins from African medicinal plants as potential pharmaceuticals to fight cancer, and the refractory phenotypes
Jenifer R. N. Kuete, Robert V. T. Kepdieu, Rémy B. Teponno, and Victor Kuete

2. Coumarins from African medicinal plants: a review of their cytotoxic potential towards drug sensitive and multidrug-resistant cancer cell lines
Vaderament-A. Nchiozem-Ngnitedem, Appolinaire Kene Dongmo, Leonel Donald Feugap Tsamo, and Victor Kuete

3. Quinones from African medicinal plants as potential anticancer pharmaceuticals
Jenifer R. N. Kuete, Leonidah Kerubo Omosa, and Victor Kuete

4. Benzophenones from African plants to fight cancers and cancer drug resistance
Vaderament-A. Nchiozem-Ngnitedem, Daniel Buyinza, and Victor Kuete

5. Flavonoids from African medicinal plants as potential pharmaceuticals to tackle cancers and their refractory phenotypes
Jenifer R. N. Kuete and Victor Kuet

6. Isoflavonoids from African medicinal plants can be useful in the fight against cancer and cancer drug resistance
Jenifer R. N. Kuete, Armelle T. Mbaveng, Leonidah K. Omosa, and Victor Kuete

7. Cytotoxic lignans, neolignans, and stilbenes from African medicinal plants
Victor Kuete, Ibrahim Hashim, and Leonidah K. Omosa

8. Pharmaceutical xanthones from African medicinal plants to fight cancers and their recalcitrant phenotypes
Hugues Fouotsa, Julio Issah Mawouma Pagna, and Victor Kuete

9. Alkaloids from African plants as pharmaceuticals to combat cancer drug resistance
Vaderament-A. Nchiozem-Ngnitedem, Justus Mukavi, Leonidah Kerubo Omosa, and Victor Kuete

Product details

  • Edition: 1
  • Latest edition
  • Volume: 115
  • Published: March 3, 2025
  • Language: English

About the editors

VK

Victor Kuete

Professor Victor Kuete is a distinguished Cameroonian scientist and Full Professor of Pharmacognosy at the University of Dschang, where he also serves as Director of the Centre for Study, Research, and Development of Natural Resources and Technologies. His career spans over two decades of groundbreaking research in natural product pharmacology, with a particular focus on African medicinal plants as sources of antimicrobial, antiviral, and anticancer agents. Kuete’s research program emphasizes the mechanisms of action of bioactive compounds, especially against multidrug-resistant (MDR) phenotypes, and has contributed significantly to the global understanding of ethnopharmacology. He has authored more than 500 scientific publications, over 120 book chapters, and several influential books, including Medicinal Plant Research in Africa (2013), Biodiversity, Natural Products and Cancer Treatment (2014), Toxicological Survey of African Medicinal Plants (2014), and African Medicinal Spices and Vegetables (2017). His more recent works, such as African Plants to Fight Bacterial Resistance (2023) and African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and Their Chemoresistance (2024–2025), further consolidate his reputation as a leading voice in pharmacognosy. Internationally, Kuete has been awarded numerous prestigious fellowships, including TWAS (2007), AUF (2008), DAAD (2009), Alexander von Humboldt (2012–2014, 2015–2018), and Tubitak (2016). These fellowships facilitated collaborations with leading scientists across Europe, Asia, and Africa, strengthening his global research network. His work has been widely cited, with over 26,000 citations and an h-index above 95, placing him among the top 100 African scientists according to the AD Scientific Index. Beyond research, Professor Kuete plays a vital role in mentorship and academic leadership, having supervised dozens of Master’s and PhD theses, many of whose graduates now hold senior academic positions across Africa. He also serves as Editor-in-Chief of Investigational Medicinal Chemistry and Pharmacology, alongside editorial roles in several international journals, reinforcing his influence in shaping the field of ethnopharmacology and drug discovery. Professor Kuete’s career exemplifies the integration of traditional African medicine with modern pharmacological science, positioning him as a global leader in the search for novel therapeutic agents to address pressing health challenges such as cancer, infectious diseases, and drug resistance.

Affiliations and expertise
Department of Biochemistry, Faculty of Sciences, University of Dschang, Dschang, Cameroon

JJ

Jean-Pierre Jacquot

Professor Jacquot has contributed to the elucidation of redox regulation in plants. Study of the thioredoxin and glutaredoxin systems and their molecular targets. His technical competence includes: plant biochemistry, genetic engineering, site directed mutagenesis, protein structure function relationship. He has 230 articles published in peer reviewed international journals. 180 accessible in Pubmed, 228 in ISI web. He has also been the Series Editor for Advances in Botanical Research (Elsevier) since 2011 and Editorial Board member of The Journal of Biological Chemistry from 2008-2013. He has been a senior member of Institut Universitaire de France since 2007 and received Gay-Lussac von Humboldt Prize Bundes Republik Deutschland Académie des sciences française, mention Biology 2009-2010. His past and present administrative duties include Member of Conseil National des Universités section 66 (2005-2007and 2011-today), Director of Structure Fédérative 4242 Ecosystèmes forestiers, Agroressources, Bioprocédés et Alimentation (EFABA) (since 2004), Director of Pôle de recherches A2F (Agronomie Agroalimentaire Forêt), Université de Lorraine (2006-2011, 2012-today) and Head of the group «Stress response and redox regulation » of UMR Interactions Arbres Microorganismes till 2012.
Affiliations and expertise
Universite Henri Poincare, Membre de L'Institut Universitaire de France, Nancy University, France

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