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Elsevier

Books in Life sciences

  • Climate Change and Agricultural Ecosystems

    Current Challenges and Adaptation
    • 1st Edition
    • Krishna Kumar Choudhary + 1 more
    • English
    Climate Change and Agricultural Ecosystems explains the causative factors of climate change related to agriculture, soil and plants, and discusses the relevant resulting mitigation process. Agricultural ecosystems include factors from the surrounding areas where agriculture experiences direct or indirect interaction with the plants, animals, and microbes present. Changes in climatic conditions influence all the factors of agricultural ecosystems, which can potentially adversely affect their productivity. This book summarizes the different aspects of vulnerability, adaptation, and amelioration of climate change in respect to plants, crops, soil, and microbes for the sustainability of the agricultural sector and, ultimately, food security for the future. It also focuses on the utilization of information technology for the sustainability of the agricultural sector along with the capacity and adaptability of agricultural societies under climate change. Climate Change and Agricultural Ecosystems incorporates both theoretical and practical aspects, and serves as base line information for future research. This book is a valuable resource for those working in environmental sciences, soil sciences, agricultural microbiology, plant pathology, and agronomy.

  • 250 examens de laboratoire

    en pratique médicale courante
    • 13th Edition
    • René Caquet
    • French
    Les examens de laboratoire, parfois qualifiés d’examens «complémentaires» alors qu’ils sont indispensables, recherchent bactéries et virus, reconnaissent les cellules anormales, détectent les anticorps, évaluent le fonctionnement des organes, scrutent le milieu intérieur, examinent les gènes.Comment s’en passer ?Ce livre, élaboré par un clinicien, offre aux professionnels de santé un instrument de pratique quotidienne. Ouvrage de référence, il expose tout ce qu’il faut savoir pour prescrire des analyses médicales et interpréter les résultats.Les examens de laboratoire sont présentés sous forme de fiches, classées par ordre alphabétique, qui suivent un plan récurrent : mode et précautions de prélèvement, valeurs normales et cliniques (valeurs pathologiques), objectifs de l’examen et interprétation.Cet ouvrage décrit le raisonnement qui permet de déduire d’un résultat biologique les meilleures conclusions diagnostiques ou thérapeutiques possibles, en interprétant les résultats à la lumière de la clinique, de la littérature scientifique et des données de santé publique.Cette 13e édition est entièrement actualisée, notamment en fonction des publications récentes, des recommandations des sociétés savantes (VIH, allergies, auto-immunité...) et en accord avec la nomenclature de la Sécurité sociale.De nouveaux examens liés à l’actualité médicale (caryotype onco-hématologique, hématocrite, hépatite E…) sont ajoutés.L’ouvrage s’accorde volontairement à la pratique des généralistes, spécialistes et biologistes. Les examens plus rares (biologie moléculaire…) sont traités en accord avec la demande.

  • Inspiring Conversations with Women Professors

    The Many Routes to Career Success
    • 1st Edition
    • Anna Garry
    • English
    Inspiring Conversations with Women Professors: The Many Routes to Career Success provides stories behind the many paths to professorship taken by these featured women. It includes information on their diverse life stories and how they navigated the beginning, middle stages, and other parts of their careers, including unexpected paths, support and how they got hooked by science/their field. In addition, they discuss why they chose this career, the obstacles they encountered, and how they found a way forward. Each interview encapsulates the advice and practical solutions they give.

  • Human Embryos and Preimplantation Genetic Technologies

    Ethical, Social, and Public Policy Aspects
    • 1st Edition
    • E. Scott Sills + 1 more
    • English
    Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions.

  • The Little Black Book of Neurology

    • 6th Edition
    • Osama O. Zaidat + 2 more
    • English
    Widely known and well-respected, The Little Black Book of Neurology has been a thorough yet portable reference in this complex field for more than 30 years, presenting definitions, classifications, and guidance on diagnosis and management for a wide range of neurological disorders. The 6th Edition offers updated and expanded coverage of neuropharmacology and neuroimaging – plus a new, more user-friendly, fast-access format that makes the book ideal for quick clinical consultation or as a refresher for the Boards.

  • Les troubles du sommeil

    • 3rd Edition
    • Yves Dauvilliers
    • French
    La médecine du sommeil est une discipline récente et les manuels qui lui sont consacrés sont peu nombreux. Les troubles du sommeil et de l’éveil touchent pourtant une part importante de la population et ont de graves répercussions sur la santé physique et mentale, ainsi que sur la qualité de vie.La 3e édition de cet ouvrage de référence, entièrement mis à jour et agrémenté de questionnaires, d’échelles et d’un glossaire étendu :• fait le point sur le sommeil normal (aspects neurobiologiques et physiologiques chez l’enfant, l’adulte et le sujet âgé),• présente les différentes méthodes d’exploration,• propose une synthèse sur les multiples troubles (insomnie, hypersomnie, troubles du rythme circadien, parasomnie…),• établie le lien entre les troubles du sommeil et les spécialités médicales : neurologie, cardiologie, pneumologie, endocrinologie, pédiatrie, psychiatrie, ORL….Cet ouvrage s’adresse aux médecins généralistes et spécialistes. Ils y trouveront des réponses à leurs questions, ainsi que de nombreuses indications pour la prise en charge des patients et la prescription de traitements. Il s’adresse également à tous les professionnels de santé, chercheurs et étudiants désireux de s’ouvrir à un domaine encore peu enseigné dans les facultés et écoles.

  • Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B
    • 1st Edition
    • Volume 163
    • English
    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B, Volume 163 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include an Overview of Fugal Glycan-based Therapeutics, Heparin: An Essential Drug for Modern Medicine, Low Molecular Weight Heparins and Their Clinical Applications, The Clinical Use of Fondaparinux: A Synthetic Heparin Pentasaccharid, Heparinoids as Clinically Used Drugs, Marine Glycan-Derived Therapeutics in China, Efficacy of Heparinoid PSS in Treating Cardiovascular and other Diseases—30 Years Clinical Applications in China, and more.

  • Intracellular Signalling Proteins

    • 1st Edition
    • Volume 116
    • English
    Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.

  • Advances in Parasitology

    • 1st Edition
    • Volume 104
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 104, the latest in a series first published in 1963, contains comprehensive reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on Leishmania Tropica, Extracellular Vesicles in Host-Parasite Interaction, Cathepsins and Vaccines for Fascioliosis, Echinococcosis Transmission on the Tibetan Plateau, A Review of Diagnostics for STH from a Public Health Perspective, and Zoonotic Transmission of Intestinal Parasites: Implications for Control and Elimination.

  • Evolution's Clinical Guidebook

    Translating Ancient Genes into Precision Medicine
    • 1st Edition
    • Jules J. Berman
    • English
    Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

  • The Comorbidities of Epilepsy

    • 1st Edition
    • Marco Mula
    • English
    Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers.

  • Advances in Agronomy

    • 1st Edition
    • Volume 155
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 155, the newest release in this valuable serial, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Context

    The Effects of Environment on Product Design and Evaluation
    • 1st Edition
    • Herbert L. Meiselman
    • English
    Context: The Effects of Environment on Product Design and Evaluation addresses the environment, or context, in which we consume products and the impact of context on choice and acceptability. The book explores what context is, how it influences design by specialists, and acceptance by consumers. Chapters discuss the basics of context, food and drink in context, testing a range of other products, and other contextual variables. Historically, research on context has been done in the laboratory and various natural locations, but rapid growth in other methods to study context, including evoked contexts, immersive contexts, virtual reality contexts, and more have widened research possibilities. Appealing to the professional, academic and commercial markets, this book will be of interest to those who conduct research in product development and product testing, to those who study what controls product usage, including eating from the health perspective, and to those who make decisions about product and space development.

  • Cadmium Tolerance in Plants

    Agronomic, Molecular, Signaling, and Omic Approaches
    • 1st Edition
    • Mirza Hasanuzzaman + 1 more
    • English
    Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches presents research and latest developments on mechanisms of cadmium tolerance covering both lab and field conditions. This book contains important insights and options for minimizing Cd accumulation in plants and mitigating Cd toxicity. Topics covered include using various omics approaches to understanding plant responses to Cd, novel technologies for developing Cd tolerance and integrated breeding approaches to mitigate Cd stress in crops. Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches is a valuable resource for both researchers and students working on cadmium pollution and plant responses as well as related fields of environmental contamination and toxicology.

  • Sex Determination in Vertebrates

    • 1st Edition
    • Volume 134
    • English
    Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells to male or female fate. Chapters in this new release cover, amongst other topics, Mapping the Sox9 Enhancer Elements, Epigenetic Regulation of Sex Determination, Evolution and Management of Sex Chromosomes, Regulation of Germ Cell Sex Identity in Medaka, Control of Sex Determination in Zebrafish, Sexually Dimorphic Germ Cell Identity in Mammals, and more.

  • Animal Models in Cancer Drug Discovery

    • 1st Edition
    • Asfar Azmi + 1 more
    • English
    Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.

  • Sleep and Health

    • 1st Edition
    • Michael A. Grandner
    • English
    Sleep and Health provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community and population levels, as well as a discussion of the implications for public health, public policy and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more.

  • Evaluation Technologies for Food Quality

    • 1st Edition
    • Jian Zhong + 1 more
    • English
    Evaluation Technologies for Food Quality summarizes food quality evaluation technologies, which include sensory evaluation techniques and chemical and physical analysis. In particular, the book introduces many novel micro and nano evaluation techniques, such as atomic force microscopy, scanning electron microscopy, and other nanomaterial-based methods. All topics cover basic principles, procedures, advantages, limitations, recent technology development, and application progress in different types of foods. This book is a valuable resource for scientists in the field of food science, engineering, and professionals in the food industry, as well as for undergraduate and postgraduate students studying food quality evaluation technology.

  • Molecular Mechanisms of Dementia

    Biomarkers, Neurochemistry, and Therapy
    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists... and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases.　

  • The Artificial Pancreas

    Current Situation and Future Directions
    • 1st Edition
    • Ricardo S. Sánchez-Peña + 1 more
    • English
    The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient’s quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.

  • Big Data Analytics for Intelligent Healthcare Management

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Big Data Analytics for Intelligent Healthcare Management covers both the theory and application of hardware platforms and architectures, the development of software methods, techniques and tools, applications and governance, and adoption strategies for the use of big data in healthcare and clinical research. The book provides the latest research findings on the use of big data analytics with statistical and machine learning techniques that analyze huge amounts of real-time healthcare data.

  • Mitochondria in Obesity and Type 2 Diabetes

    Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases
    • 1st Edition
    • Beatrice Morio + 2 more
    • English
    Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers.

  • Aging, Nutrition and Taste

    Nutrition, Food Science and Culinary Perspectives for Aging Tastefully
    • 1st Edition
    • Jacqueline B. Marcus
    • English
    Approximately 380 million people worldwide are 60 years of age or older. This number is predicted to triple to more than 1 billion by 2025. Aging, Nutrition and Taste: Nutrition, Food Science and Culinary Perspectives for Aging Tastefully provides research, facts, theories, practical advice and recipes with full color photographs to feed the rapidly growing aging population healthfully. This book takes an integrated approach, utilizing nutrition, food science and the culinary arts. A significant number of aging adults may have taste and smell or chemosensory disorders and many may also be considered to be undernourished. While this can be partially attributed to the behavioral, physical and social changes that come with aging, the loss or decline in taste and smell may be at the root of other disorders. Aging adults may not know that these disorders exist nor what can be done to compensate. This text seeks to fill the knowledge gap. Aging, Nutrition and Taste: Nutrition, Food Science and Culinary Perspectives for Aging Tastefully examines aging from three perspectives: nutritional changes that affect health and well-being; food science applications that address age-specific chemosensory changes, compromised disease states and health, and culinary arts techniques that help make food more appealing to diminishing senses. Beyond scientific theory, readers will find practical tips and techniques, products, recipes, and menus to increase the desirability, consumption and gratification of healthy foods and beverages as people age.

  • Age Estimation

    A Multidisciplinary Approach
    • 1st Edition
    • Joe Adserias-Garriga
    • English
    Age Estimation: A Multidisciplinary Approach is the only reference in the field covering all techniques and methods involving age estimation from different perspectives in just one volume. The book provides comprehensive coverage of all aspects of age estimation: aging the living and the dead, human rights, and skeletal, dental, histological and biochemical techniques and methods available. Each chapter is written by internationally known expert contributors. Age Estimation: A Multidisciplinary Approach is a one of a kind resource for those involved in estimating the age of the living and the dead.

  • Social Cognition in Psychosis

    • 1st Edition
    • Kathryn Eve Lewandowski + 1 more
    • English
    Social Cognition in Psychosis combines current research on phenotypes, neurobiology, and existing evidence on the assessment and treatment of various forms of psychoses. The book presents various treatment options, including assessment approaches, tools and training methods that aid in the rehabilitation of patients with psychotic disorders. Social cognition is a set of psychological processes related to understanding, recognizing, processing and appropriately using social stimuli in one's environment. Individuals with psychotic disorders consistently exhibit impairments in social cognition. As a result, social cognition has been an important target for intervention, with recent efforts trying to enhance early recovery among individuals with psychotic disorders.

  • Sex Differences in Cardiovascular Physiology and Pathophysiology

    • 1st Edition
    • Babbette LaMarca + 1 more
    • English
    Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.

  • Caffeinated and Cocoa Based Beverages

    Volume 8. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Caffeinated and Cocoa Based Beverages, Volume Eight in The Science of Beverages series, covers one of the hottest topics in the current beverage industry. This practical reference takes a broad and multidisciplinary approach on the production, processing, and engineering approaches to caffeinated drinks, highlighting their biological impact and health-related interference. The book presents evidence-based examples of the benefits of caffeinated and cocoa-based beverages and analyzes the latest trends in the industry that are essential for researchers in various fields of food and beverage development, including coverage of pharmaceuticals and the biomedical fields.

  • Quorum Sensing

    Molecular Mechanism and Biotechnological Application
    • 1st Edition
    • Giuseppina Tommonaro
    • English
    Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.

  • Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates

    • 5th Edition
    • George Paxinos + 1 more
    • English
    Paxinos and Franklin’s The Mouse Brain in Stereotaxic Coordinates, Fifth Edition, emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience.

  • Biomechatronics

    • 1st Edition
    • Marko B. Popovic
    • English
    Biomechatronics is rapidly becoming one of the most influential and innovative research directions defining the 21st century. Biomechatronics provides a complete and up-to-date account of this advanced subject at the university textbook level. Each chapter is co-authored by top experts led by Professor Marko B. Popovic, researcher and educator at the forefront of advancements in this fascinating field. Beginning with an introduction to biomechatronics and its historical background, this book delves into the most groundbreaking recent developments in a wide variety of subjects, such as artificial organs and tissues, prosthetic limbs, neural interfaces, orthotic systems, wearable systems for physical augmentation, physical therapy and rehabilitation, robotic surgery, natural and synthetic actuators, sensors, and control systems. A number of practice problems and solutions are provided at the end of the book. Two years in the making, the book Biomechatronics is a result of dedicated work of a team of close to thirty contributors from all across the globe including top researchers and educators from the USA (Popovic, Lamkin-Kennard, Sinyukov, Troy, Goodworth, Johnson, Kaipa, Onal, Bowers, Djuric, Fischer, Ji, Jovanovic, Luo, Padir, Tetreault), Japan (Tashiro, Iramina, Ohta, Terasawa), Sweden (Boyraz), Turkey (Arslan, Karabulut, Ortes), Germany (Beckerle, Willwacher), New Zealand (Liarokapis), and Switzerland (Dobrev).

  • Diagnostic Molecular Biology

    • 1st Edition
    • Chang-Hui Shen
    • English
    Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding. The targeted approach covers the principles of molecular biology including the basic knowledge of nucleic acids, proteins, and genomes as well as the basic techniques and instrumentations that are often used in the field of molecular biology with detailed procedures and explanations. This book also covers the applications of the principles and techniques currently employed in the clinical laboratory.

  • Echinoderms Part B

    • 1st Edition
    • Volume 151
    • English
    Echinoderms, Volume 151, the latest release in the Methods in Cell Biology series, highlights advances in the field, with this update presenting chapters on Echinoderm Genome Databases, analysis of gene regulatory networks, using ATAC-seq and RNA-seq to increase resolution in GRN connectivity, multiplex cis-regulatory analysis, experimental approaches GRN/signal pathways, BACs, analysis of chromatin accessibility using ATAC-seq, analysis of sea urchin proteins /Click IT, CRISPR/Cas9-mediated genome editing in sea urchins, super-resolution and in toto imaging of echinoderm embryos, and methods for analysis of intracellular ion signals in sperm, eggs and embryos.

  • Alcoholic Beverages

    Volume 7: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Alcoholic Beverages, Volume Seven in The Science of Beverages series, is a multidisciplinary resource for anyone who needs deeper knowledge on the most recent approaches in beverage development, technology, and engineering, along with their effects on beverage composition, quality, sensory and nutritional features. The book discusses main alcoholic beverages, such as spirits and wines that are thoroughly analyzed in terms of production, sustainability, and future perspectives. It offers examples of the new trends and the most recent technologies and approaches in the industry of alcoholic drinks.

  • Clinical Genome Sequencing

    Psychological Considerations
    • 1st Edition
    • Aad Tibben + 1 more
    • English
    Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.

  • Soilless Culture: Theory and Practice

    Theory and Practice
    • 2nd Edition
    • Michael Raviv + 2 more
    • English
    Soilless Culture: Theory and Practice, Second Edition, is the first authoritative reference book on both the theoretical and practical aspects of growing plants without the use of soil. It is the go-to source for those involved in this practice, focusing on hydroponics and advancements in technologies and methodologies. The book builds on the thorough presentation of both physical and chemical properties of various soilless growing media, also addressing how these properties affect plant performance in basic horticultural operations, such as irrigation and fertilization. In addition, the book describes the latest technical advancements and methodologies, including run-to-waste, re-circulation and closed systems.

  • Pharmaceutical Quality by Design

    Principles and Applications
    • 1st Edition
    • Sarwar Beg + 1 more
    • English
    Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process.

  • The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle

    • 1st Edition
    • Eric Murillo-Rodriguez
    • English
    The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it.

  • Nasopharyngeal Carcinoma

    From Etiology to Clinical Practice
    • 1st Edition
    • Anne W.M. Lee + 2 more
    • English
    Nasopharyngeal Carcinoma: From Etiology to Clinical Practice discusses NPC from basic science, to clinical management through the perspective of members of the Centre for Nasopharyngeal Carcinoma Research in Hong Kong. It encompasses not only the most detailed information about multiple aspects of NPC, but also the modern day research model of scientist-clinician collaboration, focusing on bench-to-bedside approach. Basic science is covered, discussing genetics and genomics in NPC and its epidemiology and the role of Epstein-Barr Virus (EBV). Translational research is also covered, presenting topics such as animal models, plasma EBV DNA, molecular imaging and immunotherapy, amongst other topics. This book is a valuable source for cancer researchers, oncologists, medical oncologists and several members of the biomedical field who are interested in learning more about NPC management from both clinical and research perspectives.

  • Ubiquitin-dependent Protein Degradation

    • 1st Edition
    • Volume 619
    • English
    Ubiquitination and Protein Stability - Part B, Volume 619, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Topics of note include chapters on Assays of SUMO protease function in mammalian cells, In vitro analysis of proteasome-associate... USP14 activity for substrate degradation and deubiquitylation, Methods to study proteasome regulatory particle assembly, Native mass spectrometry approaches to study the proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway, and much more.

  • Data Processing Handbook for Complex Biological Data Sources

    • 1st Edition
    • Gauri Misra
    • English
    Data Processing Handbook for Complex Biological Data provides relevant and to the point content for those who need to understand the different types of biological data and the techniques to process and interpret them. The book includes feedback the editor received from students studying at both undergraduate and graduate levels, and from her peers. In order to succeed in data processing for biological data sources, it is necessary to master the type of data and general methods and tools for modern data processing. For instance, many labs follow the path of interdisciplinary studies and get their data validated by several methods. Researchers at those labs may not perform all the techniques themselves, but either in collaboration or through outsourcing, they make use of a range of them, because, in the absence of cross validation using different techniques, the chances for acceptance of an article for publication in high profile journals is weakened.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 29
    • Aleš Iglič︎ + 2 more
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 29, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers.

  • Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A
    • 1st Edition
    • Volume 162
    • English
    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer Biology and Its Clinical Applications, Retrospective Analysis of Glycan-Related Biomarkers Based on Clinical Laboratory Data in Two Medical Centers, and many related topics.

  • Advances in Immunology

    • 1st Edition
    • Volume 141
    • English
    Advances in Immunology, Volume 141, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this volume focusing on recent advances in the cysteinyl leukotriene pathway and chromosome biology and immunology.

  • Nucleic Acid Sensing and Immunity - PART B

    • 1st Edition
    • Volume 345
    • English
    Nucleic Acid Sensing and Immunity - PART B, Volume 345 gives a comprehensive overview of the nucleic acid machinery, from plants to mammalians, along with their regulation. Chapters in this updated volume include Nucleic acids sensing in allergic disorders, Nucleic acids sensing in autoimmune disorders, Nucleic acid sensing in inflammatory disorders, Viral nucleic acid sensing inflammasomes in intestinal host defense, Genome damage sensing leads to tissue homeostasis in Drosophila, Nucleic acids sensing in plants, Nucleic Acid sensing in invertebrates, amongst other topics.

  • Vertebrate Skeletal Development

    • 1st Edition
    • Volume 133
    • English
    Vertebrate Skeletal Development, Volume 133, the latest release in the Current Topics in Developmental Biology series, presents interesting chapters on a variety of topics, with this edition focusing on Craniofacial skeletal development, Regulatory mechanism of jawbone and tooth development, Development of the axial skeleton and intervertebral discs, Stem and progenitor cells in skeletal development, Origin, functioning and morphogenetic activity of limb synovial joint, ECM signaling in cartilage development and endochondral ossification, Sox genes in skeletal development, Wnt-Signaling in Skeletal Development, Gαs signaling in skeletal development and diseases, FGF signaling in skeletal development, Bone morphogenetic growth factors in bone development, and more.

  • Neuroscience of Nicotine

    Mechanisms and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process.

  • Advances in Genetics

    • 1st Edition
    • Volume 103
    • English
    Advances in Genetics, Volume 103, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • Neuroscience of Alcohol

    Mechanisms and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance.

  • Epidemiology of Diabetes

    • 1st Edition
    • Jahangir Moini
    • English
    Epidemiology of Diabetes addresses the patterns, risk factors and prevention tactics for the epidemic of diabetes in the US population. Diabetes is a costly and common disease that needs serious attention and awareness. Diabetes causes devastating consequences, such as neuropathy, retinopathy, nephropathy and vasculopathy. This succinct reference focuses on current data and research on diabetes, and is essential reading for diabetes care providers, as well as health care decision-makers. The Centers for Disease Control and Prevention has reported that more than 100 million US adults are living with diabetes or prediabetes, hence this is a timely resource on the topic.

  • Encyclopedia of Ocean Sciences

    • 3rd Edition
    • J. Kirk Cochran + 2 more
    • English
    The oceans cover 70% of the Earth’s surface, and are critical components of Earth’s climate system. This new edition of Encyclopedia of Ocean Sciences, Six Volume Set summarizes the breadth of knowledge about them, providing revised, up to date entries as well coverage of new topics in the field. New and expanded sections include microbial ecology, high latitude systems and the cryosphere, climate and climate change, hydrothermal and cold seep systems. The structure of the work provides a modern presentation of the field, reflecting the input and different perspective of chemical, physical and biological oceanography, the specialized area of expertise of each of the three Editors-in-Chief. In this framework maximum attention has been devoted to making this an organic and unified reference.

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