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Elsevier

Books in Organic chemistry

This collection offers extensive coverage of organic synthesis, reaction mechanisms, and functional group chemistry. Showcasing innovative research, green chemistry approaches, and industrial applications, it supports chemists, students, and researchers in designing new molecules and materials. Addressing drug discovery, polymers, and sustainable processes, these titles foster creativity and technical excellence in advancing organic chemistry for societal benefit.

  • Cancer Drug Design and Discovery

    • 1st Edition
    • Stephen Neidle
    • English
    The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumors. Unique sections explain the basic underlying principles of cancer drug development and provide a practical introduction to modern methods of drug design. Appealing to a broad audience, this is an excellent reference for translational researchers interested in cancer biology and medicine as well as students in pharmacy, pharmacology, or medicinal and biological chemistry and clinicians taking oncology options.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 55
    • Robert C. West + 2 more
    • English
    Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 61
    • English
    Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 19
    • Gordon Gribble + 1 more
    • English
    This is the 19th annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2006. As with previous volumes in the series, Volume 19 will enable the reader to keep abreast of developments in heterocyclic chemistry in an effortless way.

  • Lectins: Analytical Technologies

    • 1st Edition
    • Carol L. Nilsson
    • English
    Lectins: Analytical Technologies covers both analytical and biological aspects of lectins (functional carbohydrate (complex sugar) recognition proteins) and provides researchers in the field with a resource containing background information and 'look-up' tables detailing lectin specificity and structures. Also included are methods and practical tips for designing new lectins from existing non-lectin proteins, automated approaches to lectin proteomics and high resolution mass spectrometry techniques. This book will be of interest to both novice and advanced researchers in biomedical, analytical and pharmaceutical fields who are involved in the study of lectin structures or who utilize lectins as analytical tools. The study of lectins and their employment in analytical settings spans a range of fields including: * Crystallography and lectin structure databases* Carbohydrate microarrays for lectin characterization and glycotope identification* Proteomic approaches to the functional identification of bacterial adhesins* Generation of lectins from enzymes* Probing cell-surface lectins with neoglycoconjugates

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 94
    • Alan R. Katritzky
    • English
    Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Volume 94 of Advances in Heterocyclic Chemistry commences with a review of cascade reactions on heterocyclic synthesis. The chapter presents a fascinating array of complex sequences which provide efficient routes to a wide variety of heterocyclic systems. The second chapter is the twelfth in the series on the organic chemistry of heterocyclic ligands in metallic complexes. The present contribution deals with the chemistry of polypyridine ligands in organomanganese and organorhenium complexes. Its current importance can be measured by the fact that, of the nearly 700 references, approximately half date from the last 10 years. Preparation of aminoisoxazoles and their utility in the synthesis of condensed systems are also covered. In the final chapter, isothiazolium salts and their use in synthesis are reviewed. Many condensed S,N-heterocyclic systems are described in this, the first review dedicated to this topic.

  • Significant Pharmaceuticals Reported in US Patents

    • 1st Edition
    • Thomas F. DeRosa
    • English
    Significant Pharmaceuticals Reported in US Patents identifies the next generation of pharmaceuticals reported in US Patents. This "hands-on" title provides explicit laboratory methods for preparing the most recent and effective medications. Each entry documents the biological testing protocols used to evaluate a drug and the significance of the current treatment agent over previous methods. Pharmaceuticals are included in this review only if at least two of the following criteria were met: Effectiveness in treating an illness, Innovative, ease of preparation, synergy with existing Medications. Pharmaceuticals are reported for 27 separate classes of illness, including: AIDS, Alzheimer's Disease, Cardiovascular Disorders, Diabetes, Epilepsy, Hepatitis C, Osteoporosis, Obesity and Sleep Disorders. Significant Pharmaceuticals Reported in US Patents has been designed to be used as both a reference and synthetic guide for pharmaceutical, medicinal and organic chemists and graduate students. Researchers working in other areas will also find the information valuable as in many instances intermediates or the next generation pharmaceutical are readily convertible into other industrial products including: anti-oxidants, chemical additives, herbicides, polymer precursors, water purification agents. Clear structural depictions of reagents and chemical transformations have been supplied to permit the identification of other future applications.

  • Alkaloids - Secrets of Life:

    Aklaloid Chemistry, Biological Significance, Applications and Ecological Role
    • 1st Edition
    • Tadeusz Aniszewski
    • English
    Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life.Alkaloids-Chemi... Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis.

  • Tellurium in Organic Synthesis

    Second, Updated and Enlarged Edition
    • 2nd Edition
    • Nicola Petragnani + 1 more
    • English
    The increasing number of publications that use tellurium clearly demonstrates the important role of tellurium compounds as unique and powerful tools in a broad range of organic chemical manipulations, often characterized by their selective behavior. Tellurium in Organic Synthesis provides an overview of the principal aspects of organic tellurium chemistry. Many chapters have been enriched and updated in this second edition. New chapters include overviews of toxicology and pharmacology and a review on the preparation and reactivity of several tellurium heterocycles. The first part of the book focuses on the preparation of selected inorganic tellurium compounds and on the main classes of organotellurium compounds. The second part, and main interest of the book, details the use of these inorganic and organic compounds as reagents to perform specific organic manipulations and synthesis. Reactions covered include reduction, formation and reaction of anionic species, deprotection, tellurium cyclizations, formation of alkenes, use of vinyllic tellurides, free radical chemistry, transmetallations, and removal of tellurium.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 45
    • F.D. King + 1 more
    • English
    The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.

  • Structural Chemistry of Inorganic Actinide Compounds

    • 1st Edition
    • Sergey Krivovichev + 2 more
    • English
    Structural Chemistry of Inorganic Actinide Compounds is a collection of 13 reviews on structural and coordination chemistry of actinide compounds. Within the last decade, these compounds have attracted considerable attention because of their importance for radioactive waste management, catalysis, ion-exchange and absorption applications, etc. Synthetic and natural actinide compounds are also of great environmental concern as they form as a result of alteration of spent nuclear fuel and radioactive waste under Earth surface conditions, during burn-up of nuclear fuel in reactors, represent oxidation products of uranium miles and mine tailings, etc. The actinide compounds are also of considerable interest to material scientists due to the unique electronic properties of actinides that give rise to interesting physical properties controlled by the structural architecture of respective compounds. The book provides both general overview and review of recent developments in the field, including such emergent topics as nanomaterials and nanoparticles and their relevance to the transfer of actinides under environmental conditions.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 41
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

  • Coherent Synchronized Oxidation Reactions by Hydrogen Peroxide

    • 1st Edition
    • Tofik M. Nagiev
    • English
    Describes the relations between reactions in chemical and biochemical systems with special emphasis to high selective oxidation reactions by hydrogen peroxide.Outlines possible ways for the application of these reactions in an industrial scale.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 63
    • Geoffrey A. Cordell
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • Comprehensive Medicinal Chemistry II

    • 2nd Edition
    • David J Triggle + 1 more
    • English
    The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.Also available online via ScienceDirect (2006) – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedire...

  • Palladium in Heterocyclic Chemistry

    A Guide for the Synthetic Chemist
    • 2nd Edition
    • Jie Jack Li + 1 more
    • English
    Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially. These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of Palladium in Heterocyclic Chemistry is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 1. Palladium chemistry of heterocycles has its "idiosyncrasies" stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containi... natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles. Many heterocycle-containi... natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field. It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting field.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 41
    • John P. Richard
    • English
    Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid state physics.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 41
    • John P. Richard
    • English
    Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid state physics.

  • Palladium in Heterocyclic Chemistry

    A Guide for the Synthetic Chemist
    • 2nd Edition
    • Volume 26
    • Jie Jack Li + 1 more
    • English
    Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially. These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of the book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 1. Palladium chemistry of heterocycles has its “idiosyncrasies” stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containi... natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles. Many heterocycle-containi... natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field. It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting area.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 92
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Lead Molecules from Natural Products

    Discovery and New Trends
    • 1st Edition
    • Volume 2
    • English
    Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered.The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 91
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 60
    • English
    Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 90
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 54
    • Robert C. West + 2 more
    • English
    Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. The widely acclaimed serial Advances in Organometallic Chemistry contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 44
    • F.D. King + 1 more
    • English
    The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biote... industry as escalating R&D costs are not being matched by increased output. Few observers doubt that selecting the right targets, ie those which are critical to disease pathology and are ‘druggable’, is the best starting point for improved productivity.The seven chapters of this volume describe recent progress towards drugs acting at a range of ‘druggable’ targets. One chapter addresses kinases, one covers an ion channel, two proteases are featured and three of the chapters cover G-protein coupled receptors, which has historically perhaps been the most fruitful area for medicinal chemists.

  • Advances in Synthetic Organic Chemistry and Methods Reported in US Patents

    • 1st Edition
    • Thomas F. DeRosa
    • English
    Advances in Synthetic Organic Chemistry and Methods Reported in US Patents provides synthetic guidelines for preparing current and commercially significant organic compounds, derivatives, and intermediates as reported in issued US Patents. Industries surveyed include agrochemical, cosmetics and personal care products. Each entry contains extensive information such as explicit laboratory directions for preparing all chemical intermediates and characterization data. Furthermore, product optimization studies, industrial preparation, and new synthetic methods have been included for selected entries, as well as projected research directions for future product development. In Advances in Synthetic Organic Chemistry and Methods Reported in US Patents the author's practical approach enables readers to identify research and market trends, and stay up-to-date on current developments in the field.

  • Pharmaceutical Manufacturing Encyclopedia, 3rd Edition Database

    • 3rd Edition
    • William Andrew William Andrew Publishing
    • English
    This industry standard database on pharmaceutical manufacturing processes has been completely updated to include FDA drugs approved up to the summer of 2004. The database gives details for the manufacture of 2226 pharmaceuticals that are being marketed as a trade-named product somewhere in the world. Each entry includes:ò Therapeutic function ò Chemical and common nameò Structural Formulaò Chemical Abstracts Registry no.ò Trade name, manufacturer, country, and year introducedò Raw Materialsò Manufacturing ProcessIn addition, references are also cited under each drug's entry to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products. The database is for the Windows OS.

  • Studies in Natural Products Chemistry

    Bioactive Natural Products (Part M)
    • 1st Edition
    • Volume 33
    • Atta-ur Rahman
    • English
    Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 40
    • Annette M. Doherty
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

  • Chemistry and Biology of Heparin and Heparan Sulfate

    • 1st Edition
    • Hari G. Garg + 2 more
    • English
    The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area.

  • The Chemistry of Radical Polymerization

    • 2nd Edition
    • Graeme Moad + 1 more
    • English
    In the ten years since the first edition appeared the renaissance in Free Radical Polymerization has continued to gain momentum. In this second revised edition, the authors critically evaluate the findings of the last decade, where necessary reinterpreting earlier work in the light of these ideas, and point to the areas where current and future research is being directed. The overall aim is to provide a framework for further extending our understanding of free radical polymerization and create a definable link between synthesis conditions and polymer structure and properties. The authors have updated all chapters, and added many new references and two new chapters to reflect the significant advances made in radical polymerization. One new chapter has been devoted to the area of living radical polymerization which is now responsible for a very substantial fraction of the papers in the field. In addition to offering polymers with unique compositions and properties not achievable with other methodologies, living radical polymerization has also been combined with other processes and mechanisms to give structures and architectures that were not previously thought possible. The developments are seen to have great application particularly in the emerging areas of electronics, biotechnology and nanotechnology.

  • The Chemistry of Evolution

    The Development of our Ecosystem
    • 1st Edition
    • R.J.P Williams + 1 more
    • English
    Conventionally, evolution has always been described in terms of species. The Chemistry of Evolution takes a novel, not to say revolutionary, approach and examines the evolution of chemicals and the use and degradation of energy, coupled to the environment, as the drive behind it. The authors address the major changes of life from bacteria to man in a systematic and unavoidable sequence, reclassifying organisms as chemotypes. Written by the authors of the bestseller The Biological Chemistry of the Elements - The Inorganic Chemistry of Life, the clarity and precision of The Chemistry of Evolution plainly demonstrate that life is totally interactive with the environment. This exciting theory makes this work an essential addition to the academic and public library.

  • Microwave-assisted Organic Synthesis

    One Hundred Reaction Procedures
    • 1st Edition
    • Volume 25
    • D. Bogdal
    • English
    Microwave-assisted Organic Synthesis: One Hundred Reaction Procedures provides readers with a broad overview of microwave assisted Organic Synthesis, enabling students and researchers alike to produce more efficient and high yield syntheses while saving time and resources. The work addresses key problems faced by chemistry laboratories in academia and in industry, that of an ever increasing need for procedures which are low-waste, energy efficient, high yield, occur over a short reaction period, and use environmentally friendly solvents. All these factors play an important role in the development of Green Chemistry methods, and in this, Microwave-assisted Organic Synthesis: One Hundred Reaction Procedures is an excellent resource for any library.

  • Microwave-assisted Organic Synthesis

    One Hundred Reaction Procedures
    • 1st Edition
    • Volume 25
    • D. Bogdal
    • English
    Microwave-assisted Organic Synthesis: One Hundred Reaction Procedures provides readers with a broad overview of microwave assisted organic synthesis, enabling students and researchers alike to produce more efficient and high yield syntheses while saving time and resources. The work addresses key issues faced by chemistry laboratories in academia and in industry, including an ever increasing need for procedures which are low-waste, energy efficient, high yield, occur over a short reaction period, and use environmentally friendly solvents. All these factors play an important role in the development of "green chemistry" methods, making this book an excellent resource for any laboratory or library.

  • Studies in Natural Products Chemistry

    Bioactive Natural Products (Part L)
    • 1st Edition
    • Volume 32
    • Atta-ur- Rahman
    • English
    Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 40
    • John P. Richard
    • English
    Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding applications from biology to solid state physics. This text is ideal for those interested in the relationship between the structure and function of organic compounds, including physical and theoretical chemists as well as organic and bioorganic chemists.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 89
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 62
    • Geoffrey A. Cordell
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 61
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, and various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 6
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 6
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 17
    • Gordon Gribble + 1 more
    • English
    This is the seventeenth annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2004 on most of the important heterocyclic ring systems. The volume opens with two specialized reviews: Dennis Wright covers Furans as Versatile Synthons for Target-Oriented and Diversity-Oriented Synthesis; and John Hepworth and Mark Heron discuss 'The Synthesis and Photochromic Properties of Naphthopyrans'. The remaining chapters examine the recent literature on the common heterocycles in order of increasing ring size and the heteroatoms present.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 39
    • English
    Volume thirty-nine in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 88
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 43
    • English
    The Progress in Medicinal Chemistry series spans a wide range of topics of interest to the drug discovery community. This particular volume touches upon the following:* The Herg ion channel * Fluorescence-based high throughput assay * Aprepitant and neurokinin receptors * Muscarinic receptor targets * Gene activation pathways * Malaria and antimalarial drugs * HIV virus mutation and new therapeuticsProgress in Medicinal Chemistry is available online on ScienceDirect — full-text online of volumes 41 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier’s extensive researcher network. For more information about the Elsevier Book Series on ScienceDirect Program, please visit:http://www.inf...

  • Studies in Natural Products Chemistry

    Bioactive Natural Products (Part K)
    • 1st Edition
    • Volume 30
    • Atta-ur Rahman
    • English
    Many aspects of basic research programmes are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 30 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural product, and medicinal chemistry.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 52
    • Robert C. West + 1 more
    • English
    Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. The widely acclaimed serial Advances in Organometallic Chemistry contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.

  • Analytical Pyrolysis of Synthetic Organic Polymers

    • 1st Edition
    • Volume 25
    • Serban C. Moldoveanu
    • English
    Analytical Pyrolysis of Synthetic Organic Polymers is a follow-up to Analytical Pyrolysis of Natural Organic Polymers, which is volume 20 of the series. The main focus of the book is on practical applications of analytical pyrolysis in synthetic organic polymer identification and characterization. The first part of the book has five chapters including an introduction, a discussion on physico-chemistry of thermal degradation of synthetic polymers and on instrumentation used in analytical pyrolysis, a chapter discussing what type of information can be obtained from analytical pyrolysis, and a chapter dedicated to the analysis and characterization of synthetic polymers.The second part systematically covers the analytical pyrolysis of various classes of synthetic polymers. Some theoretical background for the understanding of polymer structure using analytical pyrolysis is also discussed.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 87
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area, one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

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