Skip to main content
Elsevier

Books in Life sciences

  • CDK4/6 inhibitors in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 3 more
    • English
    CDK4/6 inhibitors in Breast Cancer Therapy examines the pivotal role of CDK4/6 inhibition in treating hormone receptor-positive (HR+)/HER2-negative advanced breast cancer. The book highlights FDA-approved applications of these inhibitors alongside endocrine therapy and explores ongoing research into their potential as neoadjuvant treatments. It provides insights into the drug discovery and development of CDK4/6 inhibitors, covering their molecular mechanisms, pharmacology, and clinical applications. Chapters address their use in mono and adjuvant therapies, as well as challenges in targeting, while also discussing market potential and post-marketing safety issues.This book is a valuable resource for researchers and academics, enhancing understanding of CDK4/6 inhibitors' chemistry and therapeutic implications. By presenting detailed information on clinical trials and market formulations, it equips the audience with essential knowledge to navigate the complexities of targeted breast cancer therapies and contributes to advancing research in this critical area.

  • Microbial Technologies for Sustainable Waste Management

    • 1st Edition
    • Rajneesh Kumar + 2 more
    • English
    Microbial Technologies for Sustainable Waste Management explores advanced waste management through microbial processes. The book investigates the current limitations of traditional waste treatment and the potential for microbial cell factories in bringing innovative solutions to this field. Beginning with an introduction to the role of microbes in waste management, it examines global case studies demonstrating success stories in microbial waste treatment and microbial innovations for biotechnological applications in waste conversion. Concluding chapters focus on microbial pathways for anaerobic digestion, hydrolysis, and fermentation, and microbial technologies for industrial applications such as wastewater treatment and the biofuel industry.Additionall... the book considers microbial remediation of hazardous and toxic waste, microbial fuel cells, and strategies for plastic waste degradation. Emerging technologies, such as AI integration, microbial nanotechnology, and engineered microbes are discussed, along with their environmental impacts and potential for scaling up to commercial applications.

  • Viruses as Therapeutic Agents for Cancer

    • 1st Edition
    • Volume 171
    • English
    Viruses as Therapeutic Agents for Cancer, Volume 171 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Coxsackievirus virotherapy, Oncolytic reovirus, Cancer immunotherapy with oncolytic myxoma virus, Zika Virus as an Oncolytic Therapy, Nonreplicative adenoviral vectors for cancer, VSV Oncolytic Virotherapy, AAV vectors for cancer gene therapy, Adenovirus cancer vaccines, Advancing Clinical Translation of Oncolytic Adenoviruses, and Immunotherapuetic Cancer Terminator Viruses.

  • Cell Death Part D

    • 1st Edition
    • Volume 209
    • English
    Cell Death Part D explores the latest advances in the mechanisms, regulation, and significance of cell death in health and disease. Covering diverse topics such as apoptosis, necrosis, autophagy, and emerging pathways, this volume presents current research and novel insights from leading experts. It serves as a valuable resource for researchers, clinicians, and students interested in understanding cellular processes and their implications for therapy and diagnostics.

  • Nanophytomedicine

    Harnessing Phytochemicals for Advanced Therapeutics
    • 1st Edition
    • Ali Zarrabi + 2 more
    • English
    Nanophytomedicine: Harnessing Phytochemicals for Advanced Therapeutics explores the integration of phytochemicals and nanotechnology to develop advanced therapeutic solutions. The book offers an extensive overview of phytochemicals, explaining their sources, extraction methods, classifications, and applications in medicine. This emerging field aims to utilize the natural properties of phytochemicals to create innovative treatments for various diseases, with a particular focus on hard-to-treat conditions such as cancer. By combining plant-derived compounds with nanomaterials, researchers are unlocking new potential in precision medicine, seeking to enhance the efficacy of treatments while minimizing side effects and improving patient outcomes.In 18 comprehensive chapters, the book delves into the therapeutic properties of phytochemicals, such as their antioxidant, antifungal, and anti-inflammatory effects. It highlights the role of these compounds in combating diseases including cancer, neurological disorders, diabetes, and cardiovascular diseases. The use of nano drug delivery systems is emphasized, showcasing how these technologies can improve the delivery and effectiveness of phytochemicals.

  • Metabolic Memory

    Past, Present and Future Implications
    • 1st Edition
    • Jeena Gupta
    • English
    Metabolic Memory: Past, Present and Future Implications delves into the emerging concept of metabolic memory, exploring how our body's metabolic processes retain a 'memory' of past experiences and how this impacts our current and future health. Drawing on the latest scientific research this book aims to bridge the gap between complex scientific concepts and their practical implications for everyday health and wellness. Metabolic memory has profound implications for understanding chronic diseases, particularly diabetes, cardiovascular diseases, and obesity. Despite its significance, there is a lack of comprehensive resource that make this information accessible to both professionals and the general public. This book fills that gap, providing a detailed yet understandable exploration of how past metabolic states influence present and future health outcomes.

  • Medical and Health Genomics of South Asia

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

  • Smart Aquaponic Farming

    An Intelligent Production System for Aquaponics
    • 1st Edition
    • Daoliang Li
    • English
    Smart Aquaponic Farming: An Intelligent Production System for Aquaponics describes the aquaponics AI factory, an ecologically efficient and sustainable multitrophic production model. While traditional aquaculture systems produce farming waste with environmental and food safety implications, the aquaponics model offers a circular organic production method that recycles and reuses aquatic waste to expand the ecological planting scene. Given recent developments in intelligent sensing, information processing, and agricultural equipment technologies, this book provides a much-needed technical guide for industry scientists and technicians. Written by leading experts in aquaculture biosystems engineering, this book reviews technology assembly, system realization, and industrial development of intelligent aquaponics AI factory models. Early chapters introduce the concept of AI factory infrastructure before exploring recirculating aquaculture systems, hydroponic planting systems, and various control systems to maintain air quality, water quality, and fish nutrition. Concluding chapters discuss AI factory system integration, sustainability evaluation, and global case studies of proof-of-concept systems. Smart Aquaponic Farming provides in-depth conceptual analyses, technical overviews, and case presentations to demonstrate the characteristics, advantages, and significance of industrial scale-up for aquaponics. It bridges the gap in disseminated knowledge on analysis, design, and implementation of aquaponics AI factories, making it an indispensable resource for aquaponics producers, technicians, industry scientists, and academics alike.

  • Navigating Tuberculosis

    Insights into Host-Pathogen Protein Interactions
    • 1st Edition
    • Mohammad Shariq + 2 more
    • English
    Navigating Tuberculosis: Insights into Host-Pathogen Protein Interactions, the latest release in the Foundations and Frontiers in Enzymology series, explores the interactions between host proteins and the tuberculosis pathogen, Mycobacterium tuberculosis (M. tb), emphasizing their roles in virulence and pathogenesis. The book delves into mechanistic insights, focusing on their roles in modulating innate and adaptive immunity and understanding TB pathomechanisms by elucidating the interplay between host defenses and M. tb infection. It provides a foundation for developing targeted mitigation strategies and discusses key regulatory pathways and protein factors involved in host-pathogen interactions, informing the design and implementation of innovative approaches to combat TB.This comprehensive volume aims to advance knowledge and strategies to combat tuberculosis, aligning with the World Health Organization's goal of eradicating TB by 2035 by addressing the need for up-to-date information on host-pathogen interactions in tuberculosis and incorporating the latest research findings and advancements. It highlights emerging therapeutic targets among host and TB pathogen proteins and integrates multidisciplinary approaches from microbiology, immunology, and molecular biology, offering a holistic perspective on TB pathophysiology. Researchers will find detailed discussions on key host proteins involved in tuberculosis pathogenesis, the molecular tactics employed by M. tb to subvert host defenses, and host-mediated inhibition strategies targeting M. tb.

  • Harnessing Plant-Stimulating Molecules

    Innovations in Stress Biology and Crop Resilience
    • 1st Edition
    • M. Iqbal R. Khan + 1 more
    • English
    Harnessing Plant-Stimulating Molecules serves as an authoritative reference on the multifaceted molecular regulators and biotechnological innovations underpinning plant resilience to environmental stressors. This volume delivers an exhaustive treatment of diverse classes of signaling entities—including phytohormones, secondary messengers, secondary messengers, reactive oxygen and nitrogen species, and heterotrimeric G proteins—elucidating their roles in complex stress adaptation pathways.In addition to molecular and biochemical foundations, this book explores advanced methodologies such as nanoparticle-facilit... metabolic modulation, RNA interference, and gene-editing strategies aimed at optimizing nutrient utilization. It also highlights the emerging significance of biostimulants in modulating plant–microbe interactions and interplant signaling networks. Detailed discussions on systemic signaling mediated by mobile molecules and photoreceptor-mediat... photomorphogenic responses further enrich the scope.By integrating cutting-edge approaches, particularly CRISPR–Cas systems, with computational modeling for simulating metabolic networks, the volume facilitates accelerated crop improvement strategies essential for addressing contemporary challenges in food security and agroecosystem sustainability.Desig... as an indispensable resource for researchers, advanced graduate students, and industry professionals, Harnessing Plant-Stimulating Molecules bridges fundamental plant molecular biology with translational biotechnology, fostering the development of resilient, high-performance crops adapted to the challenges of a changing climate.

Related subjects