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Books in Life sciences

  • Handbook of Pharmaceutical Wet Granulation

    Theory and Practice in a Quality by Design Paradigm
    • 2nd Edition
    • Ajit S. Narang + 1 more
    • English
    Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm, Second Edition offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. This completely revised and updated edition features five new chapters covering new AI tools applied to scaling up granulation processes, model drive design, machine learning models for granule property prediction, design and scale up of fluid bed granulation, and process analytical methods. This book is the prefect reference for pharmaceutical manufacturing professionals. Academic researchers will benefit from the practical advice provided by the editors and chapter authors.
  • DNA in Health, Identity, and Ancestry

    • 1st Edition
    • Hisham Atan Edinur + 2 more
    • English
    DNA in Health, Identity and Ancestry examines the human genome and advances in molecular techniques in relation to their value in health, genetic ancestry, and forensic DNA. This book systematically presents these three areas, providing new insights into recent developments in these fields, including gene editing, ancestral fraction determination, and DNA profiling. It covers the latest advances in molecular biology to understand the pertinent issues in these areas. DNA in Health, Identity and Ancestry provides an introduction to human genomes, and then delves into health, forensics and ancestry across 36 chapters. Each section is concluded with practical case studies to demonstrate the application of the principles discussed in each respective section. This book is a valuable resource for researchers, practitioners, and postgraduate students in biochemistry, molecular biology and genetics. It not only provides them with fundamental knowledge on genetics, diseases, population genetics and forensic DNA, but also presents advances, technical operational standards, analytical tools and recent developments in these respective areas.
  • Systems Biology in Crop Improvement

    Emerging Tools and Technologies
    • 1st Edition
    • Tariq Aftab
    • English
    Systems Biology in Crop Improvement offers a detailed overview of how principles and methodologies from systems biology are transforming crop research and breeding. This volume, part of the Systems Biology in Agriculture and Plant Sciences series, explores the integration of omics technologies, computational modeling, and high-throughput phenotyping to deepen our understanding of plant responses and traits.Addressing the urgent challenge of feeding a growing global population, the book emphasizes how systems biology enables insights into molecular, genetic, and environmental interactions that influence a crop’s traits and performance. It discusses applications ranging from stress resilience—abiotic and biotic—to nutrient use efficiency, nutritional enhancement, and quality markers. The volume highlights innovative strategies such as genomic editing and synthetic biology, and how these advances can be translated into practical breeding programs.Bringing together contributions from leading researchers and practitioners, Systems Biology in Crop Improvement aims to inspire new collaborations, innovations, and discoveries, ultimately contributing to a more sustainable and robust food system for future generations.
  • Non-pharmacological Interventions for Age-Related Neuropsychiatric Disorders

    • 1st Edition
    • Volume 298
    • English
    Non-pharmacological Interventions for Age-Related Neuropsychiatric Disorders, Volume 297 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Introduction to Age-Related Cognitive Behavioral Changes, The Science Behind Non-Pharmacological Interventions, Cognitive Stimulation Therapy: Enhancing Memory and Mental Function, Mindfulness and Meditation: Promoting Emotional and Cognitive Health, Music and Art Therapy: Creative Approaches to Healing, and much more.Other sections cover Physical Activity: The Brain-Body Connection, The Science Behind Reminiscence Therapy: The Healing Power of Memory, The Role of Caregivers: Providing Compassionate and Effective Care, Ethical Considerations in Non-pharmacological Interventions, and Technology-Assisted Interventions for Neuropsychiatric Disorders.
  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 47
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 47, first published in 1977, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered include ADRs, ADEs and SEDs: A Bird’s Eye View, Lithium, Drugs of abuse, Side effects of drugs used in the treatment of Alzheimer's disease, Sedatives and hypnotics, Antipsychotic agents, Anti-epileptic Medications, Side effects of opioid analgesics and narcotic antagonists, Anti-inflammatory and antipyretic analgesics and drugs used in gout, Side effects of local anesthetics and therapeutic gases, and more.Other sections covered include Antihistamines (H1 receptor antagonists), Drugs that act on the respiratory tract, Positive inotropic drugs and drugs used in dysrhythmias, Beta adrenergic antagonists and antianginal drugs, Drugs acting on the cerebral and peripheral circulations, Antihypertensive drugs, and much much more.
  • Pathophysiological Consequences of Alcohol

    • 1st Edition
    • Patricia E. Molina + 2 more
    • English
    Pathophysiological Consequences of Alcohol examines the impact of alcohol on physiological processes within various organ systems. The book starts with an introduction to relevant organ system physiology, then presents current, evidence-based findings on how alcohol use, whether acute or chronic, affects these processes. Each chapter, aside from the Introduction and Cellular and Molecular Physiology, begins with a system overview, explores alcohol's effects, and concludes with integrated cases or clinical vignettes. This volume is intended for those studying or working in physiology, biology, or neuroscience and is written by experts from a renowned Physiology Department.It includes comprehensive teaching material and offers insights into alcohol-related comorbidities. The book's authors are engaged in both research and education in the field.
  • Antimicrobial Resistance in Humans, Animals, and the Environment

    One Health Approach
    • 1st Edition
    • Kunal Ranjan + 3 more
    • English
    Antimicrobial Resistance in Humans, Animals, and the Environment: One Health Approach examines the global impact of antimicrobial resistance (AMR) with a specific focus on the interconnectedness between animal, human, and environmental health. The book details the origin, evolution and ecology of AMR and its updated epidemiology. It discusses the transmission of antimicrobial resistance between humans, animals, and the environment. It delves into the molecular mechanisms of drug resistance development and epidemiology in human and animal health; the different challenges in treating antimicrobial-resist... infections including rapid diagnosis and the development of new antimicrobial agents; and alternative strategies treating drug-resistant infections. Antimicrobial Resistance in Humans, Animals, and the Environment: One Health Approach is a useful comprehensive resource for researchers, academics postgraduate students, PhD students, early career researchers, and medical scientists in microbiology, infectious diseases, and biotechnology, public health professionals, clinical personnel treating AMR, or policymakers interested in implementing antimicrobial stewardship program in hospitals.
  • Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases

    • 1st Edition
    • Virendra Gajbhiye + 2 more
    • English
    Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases offers comprehensive coverage of the fundamentals of fungal diseases and the applications of nanotechnology for their diagnosis and treatment.The book covers the basics of human fungal pathogens, the molecular mechanisms of infection, and current diagnostic strategies and treatment regimes. It then goes on to discuss nanotechnology-based approaches for the detection and identification of human fungal pathogens. It also discusses antifungal drugs, their modes of action, and how nanoparticles are utilized to deliver these agents, highlighting their significance in treating various fungal infections. Additionally, it provides a comprehensive overview of nanotechnology-based products, as well as the current and future applications of nano-methodologies and technologies in the field of fungal infectious diseases. With contributions from experts in the field, Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases is an informative resource for scientists, researchers, and medical personnel to better understand fungal diseases in order to design and develop novel and accessible nano-based therapies for their treatment.
  • Proteomics in Cell Communication

    • 1st Edition
    • Volume 200
    • English
    Proteomics in Cell Communication, offers a comprehensive exploration of the dynamic field of proteomics and its vital role in understanding cellular communication. This book includes interesting chapters on topics such as In vivo cell-type specific secretome profiling, Assays for surface antigens in extracellular vesicles using proximity labeling strategy, Cell type-specific proximity biotinylation using TurboID to identify secreted proteins from cardiomyocytes in vitro and in vivo, Native-state and cell type-specific proteomics using TurboID proximity labeling in mouse models, Adapted Luminex approach to assess phosphoproteins and cytokines released from specific cell types in the brain in vivo, and much more.Other sections covers In-depth cell-selective proteomics and secretomics in vivo based on azidonorleucine labelling, Visualizing and profiling de novo protein synthesis in Drosophila with cell-type specificity, A Split GFP Approach for Cell-Type-Specific Protein Localization Analysis in Drosophila, Quantitative deep profiling of the cell surface proteome using the "Cell Surface Capture" technique, Proteomic profiling of extracellular fluids to identify secreted proteins from muscle and fat tissues, and much more.
  • Microbial Enzymes

    Classification, Biochemistry, Production and Applications
    • 1st Edition
    • Abdel Moneim Elhadi Sulieman
    • English
    Microbial Enzymes: Classification, Biochemistry, Production and Applications explores the multifaceted roles of microbial enzymes, emphasizing their stability, ease of handling, and manipulation, all of which make them invaluable in various industrial processes. With 25 in-depth chapters, the book delves into the biochemistry of enzymes, their various sources, and their importance in biotechnology. It covers modern techniques for microbial enzyme detection and determination, methods of enzyme immobilization, and the application of microbial enzymes in industries such as food, medicine, pharmaceuticals, and textiles. Special sections discuss the biosynthesis of metal nanoparticles by microbial enzymes and the role of microbial toxins in different sectors. The book's chapters are organized in a way that provides detailed insights into the classification of enzymes, the mechanisms of microbial enzymes, and their industrial importance. Topics include bacterial, fungal, and algal enzymes, their applications, and the latest advancements in enzyme technology. Other sections address the challenge of antibiotic resistance and explores innovative methods for enzyme production and molecular engineering.