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Books in Life sciences

Chromatin Signaling and Diseases
2nd Edition
May 1, 2026
Olivier Binda + 2 more
English
Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling.Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.
Pharmaceutical QbD with Design of Experiments
Statistical Tools and Applications in Drug Delivery Systems
1st Edition
May 1, 2026
Khushwant Yadav
English
Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.
Operative Strategies in Pelvic Exenteration Surgery
1st Edition
May 1, 2026
Michael E Kelly + 1 more
English
Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.
Encyclopedia of the Anthropocene
2nd Edition
May 1, 2026
Michael I Goldstein + 2 more
English
Encyclopedia of the Anthropocene, Second Edition, Four Volume Set, once again provides a topical-based synthesis of the unprecedented rise of humanity’s ecological footprint, the result of exponential population growth, coupled with run-away consumption of the planet’s finite ecosystem services. This new edition captures our current understanding of the actual effects of human population growth on the world’s resources, whether climate change, biodiversity loss, deforestation, soil erosion, poor air quality, or undrinkable water.Since publication of the first edition, the Anthropocene has been even more widely debated among scientists, humanists, conservationists, industry leaders, politicians and others over precisely when it began, what to call it, if it should be an official geological epoch, whether it can be contained in time, and how it will affect future generations. Sustainability has been a growing issue for the Earth's ecosystems in the Anthropocene. Humans are now using up the world's natural resources at an unsustainable rate. This is causing huge problems for the natural ecosystems, agricultural systems, and water supplies, especially in the Global South. Climate change research, through field observation and remote sensing, has enabled improved understanding of its effects, allowing us to project future effects and the adaptation measures they require. These are essential topics - all of which are fully covered in the encyclopedia.Given the high degree of public and media attention on these topics, a revised edition is timely. With over 200 concise and focused chapters written by leading scholars in the field, this reference work is uniquely positioned to make this knowledge accessible to a wide, global audience.
Molecular Mechanisms of Spermatogenesis
1st Edition
Volume 168
May 1, 2026
English
Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.
Protein-Based Nanoparticles in Drug Delivery
1st Edition
May 1, 2026
Prashant Kesharwani
English
Protein-based Nanoparticles in Drug Delivery is a comprehensive book aimed at pharmaceutical scientists and researchers both in academia and corporate environments focused on nanotechnology drug delivery and pharmaceutical-relat... disciplines. The book covers the design and characterization of various protein nanoparticles, sheds light on the power of an endogenous substance as a drug delivery system, and highlights the possible future trends in the use of protein-based drug delivery. It covers in-depth novel applications of protein-based drug delivery from fundamental to most current use cases. The book comprises three parts. Part one is devoted to the foundations of protein-based drug delivery, including nanocarriers development, drug encapsulation, targetability, and in vivo properties. Part two explores the applications of protein-based nanoparticles in drug delivery, covering topics such as protein nanoparticles in cancer therapy, genetic material delivery, and nanocarriers based on milk protein, silk, and gliadin. Part three addresses recent advances and regulatory aspects of protein-based nanoparticles in drug delivery, including clinical translation, challenges, biological toxicity, and environmental hazards associated with protein-based nanoparticles. Protein-based Nanoparticles in Drug Delivery provides a complete journey of protein-based drug delivery, offers an in-depth understanding of the design and characterization of various protein nanoparticles, and highlights possible future trends in this field. Pharmaceutical scientists will benefit from the novel applications of protein-based nanoparticles drug delivery approaches in the biological field. Nanotechnologists, biologists, chemists, physicists, engineers, and clinicians will also benefit from the foundational content provided as a basis to support communication and tackle the multidisciplinary challenges associated with research in this exciting field.
Fundamentals of Molecular Structural Biology
2nd Edition
May 1, 2026
Subrata Pal
English
Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.
Thin Film Photovoltaics
Single-Junction and Tandem
1st Edition
May 1, 2026
Jeyakumar Ramanujam + 1 more
English
Thin Film Photovoltaics: Single-junction and Tandem provides a comprehensive introduction to thin film solar cells and the latest developments in this expanding field. The book includes detailed information on material properties required for solar cells, working principles, energy band structure, charge transport to the electrodes and approaches to improve efficiency. Front-end and back-end processes are discussed in detail. Current challenges to commercial translation and potential opportunities to overcome to those challenges are also covered, and factors limiting solar cells parameters are also considered. Emphasis is on new materials and state-of-the-art technologies used for fabrication and characterization.Thi... book is suitable for researchers in academia and R&D in the subject areas of materials science and engineering, energy, physics, and chemistry.
Advances in Immunology
1st Edition
Volume 168
May 1, 2026
English
Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.
Epigenetic Mechanisms in Brain Physiology and Disorders
1st Edition
May 1, 2026
Moshe Szyf + 1 more
English
Epigenetic Mechanisms in Brain Physiology and Disorders provides a comprehensive summary of epigenetic mechanisms in brain development, from embryogenesis to aging, brain physiology and pathology. It discusses the role DNA methylation plays in regulating genomic functions, which in turn guide brain function. The book explores the epigenetic role in cell type differentiation, epigenetic processes in memory, learning, and neuronal functioning, the role of DNA methylation and other epigenetic mechanisms in sleep, feeding and metabolic control, sex, temperature regulation, and cardiovascular and blood pressure regulation. It further explores the role of epigenetic processes in neuropsychiatry disorders, neurological disease and behavioral disorders, as well as epigenetic diagnostics and therapeutics.

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