Advances in Immunology
- 1st Edition, Volume 164 - November 12, 2024
- Editors: Frederick W. Alt, Kenneth Murphy
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 5 0 8 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 5 0 9 - 6
Advances in Immunology, Volume 164, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immuno… Read more
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Request a sales quoteAdvances in Immunology, Volume 164, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding and respected serial on the subject matter
- Focuses on recent advances in the field of immunology
Immunologists and infectious disease specialists, cell biologists and hematologists
- Title of Book
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Chapter One: Unravelling the contribution of lymph node fibroblasts to vaccine responses
- Abstract
- 1 Introduction
- 2 Lymph node architecture
- 3 Fibroblast regulation of the vaccine response
- 4 Age-associated defects in lymph node fibroblasts
- 5 Concluding remarks
- Acknowledgements
- References
- Chapter Two: The multifaceted roles of TCF1 in innate and adaptive lymphocytes
- Abstract
- 1 Introduction
- 2 The TCF/LEF family and modes of gene regulation
- 3 TCF1 in T cell fate commitment and thymocyte development
- 4 TCF1 in CD8+ vs CD4+ T lineage commitment
- 5 TCF1 in CD8+ T cell activation, memory, and exhaustion
- 6 The TCF1-BLIMP1-BCL6 axis in Th1 vs Tfh differentiation
- 7 TCF1 functions in Th2 cells
- 8 TCF1 in the Th17 subset
- 9 TCF1 in Treg function
- 10 ILC development
- 11 TCF1 function in Type 1 ILCs
- 12 ILC2 subsets depend on TCF1
- 13 Roles for TCF1 in ILC3 and LTi cells
- 14 Future challenges and opportunities
- Acknowledgments
- References
- Chapter Three: System-level integrative omics analysis to identify the virus-host immunometabolic footprint during infection
- Abstract
- 1 Introduction
- 2 Virus as a metabolic engineer
- 3 Immunometabolism in infection
- 4 Multiomics systems biology
- 5 Systems biology approaches to unravel host responses in viral infections
- 6 Conclusions and future perspective
- Acknowledgments
- References
- No. of pages: 198
- Language: English
- Edition: 1
- Volume: 164
- Published: November 12, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780443295089
- eBook ISBN: 9780443295096
FA
Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USAKM
Kenneth Murphy
Kenneth M. Murphy works in Washington University School of Medecine, USA.
Affiliations and expertise
Washington University School of Medecine, USARead Advances in Immunology on ScienceDirect