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Books in Life sciences

  • Advances in CRISPR/Cas and Related Technologies

    • 1st Edition
    • Volume 178
    • March 5, 2021
    • Dipanjan Ghosh
    • English
    Advances in CRISPR/Cas and related technologies, Volume 179, the latest release in this ongoing series, deals with a wide variety of research topics related to recent advancement in the genome editing techniques. Associated chapters in this new release include Challenges for Therapeutic application of CRISPR Cas techniques, Mitochondrial DNA modification by CRISPR Cas System: Challenges and future direction, Trends in CRISPR Cas technology application in cancer, Modified CRISPR-Cas for next generation application, Application of CRISPR Cas in Synthetic Biology: Challenges and Scopes, History of CRISPR Cas system from bacterial Adaptive Immune System to research application, and more.

  • New Targeting in The Reversal of Resistant Glioblastomas

    • 1st Edition
    • Volume 14
    • March 5, 2021
    • Ali Syed Arbab
    • English
    New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field.

  • The Neuroscience of Depression

    Features, Diagnosis, and Treatment
    • 1st Edition
    • March 5, 2021
    • Colin R. Martin + 4 more
    • English
    The Neuroscience of Depression: Features, Diagnosis and Treatment, is a comprehensive reference to the diagnosis and treatment of depression. This book provides readers with the mechanisms of depression reflecting on the interplay between depression and the biological and psychosocial processes. A detailed introduction to various episodes of depression, from PTSD to post-partum depression is provided, followed by a thorough discussion on biomarkers in depression and how to diagnose depression including the Hamilton Depression Rating scale. This book also includes three full sections on treatment options for depression, including pharmacological, behavioral and other novel regimes. The Neuroscience of Depression: Features, Diagnosis and Treatment is the only resource for researchers and practitioners studying, diagnosis and treating of depression.

  • The Neuroscience of Depression

    Genetics, Cell Biology, Neurology, Behavior, and Diet
    • 1st Edition
    • March 5, 2021
    • Colin R. Martin + 4 more
    • English
    The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book provides readers with the behavior and psychopathological effects of depression, linking anxiety, anger and PSTD to depression. Readers are provided with a detailed outline of the genetic aspects of depression including synaptic genes and the genome-wide association studies (GWAS) of depression, followed by a thorough analysis of the neurological and imaging techniques used to study depression. This book also includes three full sections on the various effects of depression, including diet, nutrition and molecular and cellular effects. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is the only resource for researchers and practitioners studying depression.

  • The Mental Status Examination Handbook

    • 1st Edition
    • March 5, 2021
    • Mario F. Mendez
    • English
    The ability to effectively assess cognitive and other behavioral functions is an essential skill for neurologists, psychiatrists, geriatricians, nurses, and other clinicians who perform clinic and bedside examinations. Unique in the field, The Mental Status Examination Handbook is a user-friendly, comprehensive resource that provides practical guidance on cognitive assessment, clarifies mental status testing procedures, and assists with decision making for neuropsychological referrals. This detailed manual draws from the full history of behavioral neurology testing, making the complex and challenging area of cognitive assessment accessible for both students and practitioners.

  • Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression

    A Selection of Readings for Health Services Providers
    • 1st Edition
    • March 3, 2021
    • Robert Fried + 2 more
    • English
    Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression — A Selection of Readings for Health Services Providers presents an edited and annotated collection of recent medical journal publications and abstracts illustrating new approaches to treatment derived from the metabolic theory of cancer. It intends to shed an early light on a relatively new approach to our understanding of the cancer cell idiosyncratic metabolic dysfunction, and on evidence-based new treatment strategies derived from that understanding. The book discusses topics such as tumor starvation by L-arginine deprivation; L-canavanine depriving tumors of L-arginine in pancreatic, multiple myeloma and breast cancer; glucose deprivation and intermittent fasting; glutamine uptake in cancer; the relation of oxygen-starved cancer cells with aspartate; and reducing tolerance of tumor cells to nutrition starvation. The content is presented in a contextualized and practical way in order to facilitate the transition from bench to bedside. This is a valuable resource for practitioners, oncologists and other members of healthcare chain who are interested in learning more about the most recent tumor cell starvation strategies and how they can improve overall treatment outcome.

  • Immunopathology of Celiac Disease

    • 1st Edition
    • Volume 358
    • March 2, 2021
    • English
    Immunopathology of Celiac Disease, Volume 359 presents the latest release in this ongoing series on novel and widely studied aspects of celiac disease pathogenesis. Topics covered in this new volume include Omics of Celiac Disease, Implication of HLA genes in Celiac Disease, Macrophages & Dendritic Cells in Celiac Disease, Tight junction disruption in the development of celiac disease, Implication of epithelial cell dysfunction in CeD, Involvement of p31-p43 gluten peptide in the celiac disease related immune/inflammatory response, The biology of refractory celiac disease, Involvement of lncRNAs in Celiac disease pathogenesis, and more.

  • A Tribute to Paul Greengard (1925-2019)

    • 1st Edition
    • Volume 90
    • March 2, 2021
    • English
    A Tribute to Paul Greengard, Volume 90, the latest release in the Advances in Pharmacology series presents a variety of chapters from the best authors in the field, with this release presenting a tribute to Paul Greengard.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 101
    • March 2, 2021
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 101, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including chapters on Exosomes in cancer, Parathyroid hormone, Clinical relevance of biochemical and metabolic changes in osteoarthritis, Early diagnosis with ultrasensitive ELISA, Cytokines and the immune response in obesity-related disorders, Metabolic profiling of organic and fatty acids in chronic and autoimmune diseases, and more.

  • Clinical DNA Variant Interpretation

    Theory and Practice
    • 1st Edition
    • February 27, 2021
    • Conxi Lázaro + 2 more
    • English
    Clinical DNA Variant Interpretation: Theory and Practice, a new volume in the Translational and Applied Genomics series, covers foundational aspects, modes of analysis, technology, disease and disorder specific case studies, and clinical integration. This book provides a deep theoretical background, as well as applied case studies and methodology, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes. Practical chapters discuss genomic variant interpretation, terminology and nomenclature, international consensus guidelines, population allele frequency, functional evidence transcripts for RNA, proteins, and enzymes, somatic mutations, somatic profiling, and much more.

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