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Books in Life sciences

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    • In Situ Molecular Pathology and Co-expression Analyses

      • 2nd Edition
      • September 3, 2020
      • Gerard J. Nuovo
      • English
      • Paperback
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      • eBook
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      Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry...

    • Nano Drug Delivery Strategies for the Treatment of Cancers

      • 1st Edition
      • September 3, 2020
      • Awesh K. Yadav + 2 more
      • English
      • Paperback
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      • eBook
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      Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field.

    • Artificial Intelligence in Medicine

      • 1st Edition
      • September 3, 2020
      • Lei Xing + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 2 5 9 2
      • eBook
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      Artificial Intelligence Medicine: Technical Basis and Clinical Applications presents a comprehensive overview of the field, ranging from its history and technical foundations, to specific clinical applications and finally to prospects. Artificial Intelligence (AI) is expanding across all domains at a breakneck speed. Medicine, with the availability of large multidimensional datasets, lends itself to strong potential advancement with the appropriate harnessing of AI. The integration of AI can occur throughout the continuum of medicine: from basic laboratory discovery to clinical application and healthcare delivery. Integrating AI within medicine has been met with both excitement and scepticism. By understanding how AI works, and developing an appreciation for both limitations and strengths, clinicians can harness its computational power to streamline workflow and improve patient care. It also provides the opportunity to improve upon research methodologies beyond what is currently available using traditional statistical approaches. On the other hand, computers scientists and data analysts can provide solutions, but often lack easy access to clinical insight that may help focus their efforts. This book provides vital background knowledge to help bring these two groups together, and to engage in more streamlined dialogue to yield productive collaborative solutions in the field of medicine.

    • Plant Cell Biology

      • 1st Edition
      • Volume 160
      • August 31, 2020
      • English
      • Hardback
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      • eBook
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      Plant Cell Biology, volume 160 in "Methods in Cell Biology", includes chapters on modern experimental procedures and applications developed for research in the broad area of plant cell biology. Topics covered in this volume include techniques for imaging and analyzing membrane dynamics and movement across membranes; cell wall composition, structure and mechanics; cytoskeleton dynamics and organization; cell development; ion channel physiology; cell mechanics; and methods related to quantifying cell morphogenesis.

    • Microbiomes and Plant Health

      • 1st Edition
      • August 28, 2020
      • Manoj Kumar Solanki + 3 more
      • English
      • Paperback
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      • eBook
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      Microbiomes and Plant Health: Panoply and Their Applications includes the most recent advances in phytobiome research. The book emphasizes the use of modern molecular tools such as smart delivery systems for microbiol inoculation, next-generation sequencing, and genome mapping. Chapters discuss a variety of applications and examples, including the sugarcane microbiome, rhizoengineering, nutrient recycling, sustainable agricultural practices and bio-potential of herbal medicinal plants. Written by a range of experts with real-world practical insights, this title is sure to be an essential read for plant and soil microbiologists, phytopathologists, agronomists, and researchers interested in sustainable forestry and agriculture practices.

    • New Perspectives on Early Social-Cognitive Development

      • 1st Edition
      • Volume 254
      • August 25, 2020
      • English
      • Hardback
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      • eBook
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      New Perspectives on Early Social-Cognitive Development, Volume 258 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Dynamics of Coordinated Attention, Investigating the Role of Neural Body Maps in Early Social-Cognitive Development: New Insights from Infant MEG and EEG, Motion tracking in developmental research: Methodological considerations and social-cognitive developmental applications, Early maturation of the social brain: How brain development provides a platform for the acquisition of social-cognitive competence, Getting a grip on early intention understanding: The role of motor, cognitive, and social factors, and much more.

    • Actin Cytoskeleton in Cancer Progression and Metastasis - Part A

      • 1st Edition
      • Volume 355
      • August 25, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 2 8 1 3
      • eBook
        9 7 8 0 1 2 8 2 1 2 8 2 0
      Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, Volume 355 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.

    • Self-assessment Q&A in Clinical Laboratory Science, III

      • 1st Edition
      • August 25, 2020
      • Alan H.B. Wu
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 0 9 3 1
      • eBook
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      Self-assessment Q&A in Clinical Laboratory Science, III, adds a variety of subject matter that addresses new concepts and emerging technology, particularly in the areas of kidney biomarkers, cancer biomarkers, molecular diagnostics, multiple myeloma, pharmacogenomics, novel cardiovascular biomarkers and biomarkers of neurologic diseases. The field of Clinical Laboratory Science continues to evolve and editor Alan Wu has once again brought together experts in the field to cover the contemporary topics that are being tested today. This updated bank of questions and answers is a must-have to sharpen knowledge and skills.

    • Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases

      • 1st Edition
      • Volume 155
      • August 25, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 3 1 2 1 0
      • eBook
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      Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain – A Role in Type 2 Diabetes Mellitus and Alzheimer’s disease; and much more.

    • Systems Medicine

      • 1st Edition
      • August 24, 2020
      • Olaf Wolkenhauer
      • English
      • Hardback
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      • eBook
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      Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice.

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