Handbook of Parkinson's Disease Therapeutics
- 1st Edition - January 1, 2027
- Latest edition
- Editors: Rosario Moratalla, Mario Gustavo Murer
- Language: English
Approx.409… Read more
Description
Description
Approx.409 pages
Key features
Key features
- Covers symptoms, diagnosis, and disease management as well as therapies
- Discusses effects of different treatments and interventions
- Includes deep brain stimulation, gene therapy, focused U/S and more
- Reviews therapeutic effects on synaptic plasticity, gait, motor symptoms and more
Readership
Readership
Researchers in neuroscience, neurologists working in the field of Parkinson’s disease, researchers in pharmaceutical science. Graduate students studying neuroscience
Table of contents
Table of contents
1. History, milestones in PD and antiparkinsonian therapy research
2. Basal ganglia anatomy
3. Models of BG functional organization and their relevance to PD and antiparkinsonian therapy
4. PD diagnosis, motor symptoms and their pharmacological management
5. Non-motor symptoms and their pharmacological management
6. The prodromal phase of PD; prediction of diagnosis and prevention
7. Complications of L-DOPA therapy and their management
8. Neuropsychological spectrum symptoms in Parkinson disease
9. Impact of serotonergic system in L-DOPA therapeutic effect in PD
10. REM sleep behavior disorder and PD
11. Deep Brain Stimulation and other Functional Neurosurgery Approaches
12. Gene therapy and other promising new therapies
13. The search of a disease modifying treatments for PD
14. Magnetic resonance guided-focused ultrasound in Parkinson’s disease
15. Healthcare innovations and patient centered collaborative care in PD
16. non-invasive brain stimulation for freezing of gait and other PD symptoms non responsive to L-dopa
17. Imaging of nigrostriatal system/other systems/other biomarkers
18. Animal models for the study of PD pathophysiology and the predictive validity of treatments
19. Functional synaptic plasticity in PD and changes induced by antiparkinsonian therapy
20. Structural synaptic plasticity in PD and changes induced by antiparkinsonian therapy
21. Interventions on direct and indirect pathways with effects on motor symptoms and dyskinesia
22. Role of the GP in PD symptoms and therapeutics
2. Basal ganglia anatomy
3. Models of BG functional organization and their relevance to PD and antiparkinsonian therapy
4. PD diagnosis, motor symptoms and their pharmacological management
5. Non-motor symptoms and their pharmacological management
6. The prodromal phase of PD; prediction of diagnosis and prevention
7. Complications of L-DOPA therapy and their management
8. Neuropsychological spectrum symptoms in Parkinson disease
9. Impact of serotonergic system in L-DOPA therapeutic effect in PD
10. REM sleep behavior disorder and PD
11. Deep Brain Stimulation and other Functional Neurosurgery Approaches
12. Gene therapy and other promising new therapies
13. The search of a disease modifying treatments for PD
14. Magnetic resonance guided-focused ultrasound in Parkinson’s disease
15. Healthcare innovations and patient centered collaborative care in PD
16. non-invasive brain stimulation for freezing of gait and other PD symptoms non responsive to L-dopa
17. Imaging of nigrostriatal system/other systems/other biomarkers
18. Animal models for the study of PD pathophysiology and the predictive validity of treatments
19. Functional synaptic plasticity in PD and changes induced by antiparkinsonian therapy
20. Structural synaptic plasticity in PD and changes induced by antiparkinsonian therapy
21. Interventions on direct and indirect pathways with effects on motor symptoms and dyskinesia
22. Role of the GP in PD symptoms and therapeutics
Product details
Product details
- Edition: 1
- Latest edition
- Published: January 1, 2027
- Language: English
About the editors
About the editors
RM
Rosario Moratalla
Rosario Moratalla is a Professor of Neuroscience, Director of the Center of Interdisciplinary Research and Vice-Chair at the Cajal Institute, Consejo Superior de Investigaciones Científicas, Madrid. Dr. Moratalla‘s research interests lie on the dopaminergic system and its role in drug abuse and Parkinson’s disease. She is interested in the molecular mechanisms that modulate cellular responses in the basal ganglia motor circuit, in the context of Parkinson’s disease, L-DOPA-induced dyskinesia and impulse control disorders and drug abuse. In relationship with Parkinson's disease, her studies intend to determine the neurobiological correlates of dyskinesias induced by antiparkinsonian therapy, as well as to establish the neuronal circuits involved in non-motor symptoms of Parkinson’s disease.
Affiliations and expertise
Professor of Neuroscience, Director of the Center of Interdisciplinary Research and Vice-Chair at the Cajal Institute, Consejo Superior de Investigaciones Científicas, Madrid, SpainMM
Mario Gustavo Murer
Gustavo Murer is Professor and Chair of the Institute of Physiology and Biophysics "Bernardo Houssay" at the University of Buenos Aires School of Medicine. Dr. Murer is an expert on the functional alterations that take place in the basal ganglia in Parkinson's disease and other basal ganglia related disorders. His research focuses on the electrophysiological and morphological alterations that take place in the striatum in animal models of Parkinson's disease. His recent investigations examine how chronic dopamine depletion and dopamine replacement therapy produce changes in the activity of basal ganglia neurons, which molecular mechanisms underlie these changes, and how they modify basal ganglia function and behavior.
Affiliations and expertise
Professor and Chair of the Institute of Physiology and Biophysics "Bernardo Houssay" at the University of Buenos Aires School of Medicine. Universidad de Buenos Aires, Instituto de Fisiología y Biofísica Bernardo Houssay, Facultad de Medicina, Argentina