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Elsevier

The Neurobiological Underpinnings of Addiction Medicine

Focusing on Novel Approaches

  • 1st Edition - January 1, 2027
  • Latest edition
  • Editors: Mohammad Shabani, Mohammad Banazadeh, Mohammad Navid Ebrahimi, Silvia Turroni
  • Language: English

The Neurobiological Underpinnings of Addiction Medicine: With a Focus on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and in… Read more

Description

The Neurobiological Underpinnings of Addiction Medicine: With a Focus on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and innovative strategies for treatment. This book begins by examining the crucial role of the microbiome and the gut-brain axis in various substance use disorders, including opioid, alcohol, neurostimulant, and cannabis use disorders. It highlights how gut health can significantly influence addiction behaviors and treatment outcomes. Following this, the second section discusses the interplay between addiction and neuropsychiatric disorders such as depression, anxiety, schizophrenia, ADHD, bipolar disorder, PTSD, and OCD. This section emphasizes the impact of neurotransmitter systems and intracellular pathways on the development and persistence of these disorders. The final section introduces cutting-edge methodologies reshaping addiction research, including multi-OMICS approaches and the implications of CRISPR-Cas9 technology. By integrating these diverse topics, this book offers vital insights for clinicians and researchers alike. This essential resource is a must-read for anyone seeking to understand the complex nature of addiction and explore novel therapeutic strategies.

Key features

  • Examines the relationship between addiction and various neuropsychiatric disorders through detailed case studies
  • Highlights the significance of the microbiome in shaping therapeutic responses and treatment outcomes
  • Provides practical frameworks for clinicians to implement evidence-based interventions in their practice
  • Illustrates the complexity of neurotransmitter systems in relation to addiction and mental health disorders

Readership

Students and early researchers in neuroscience, addiction, and clinicians treating patients with addiction including psychiatrists, psychologists

Table of contents

Section 1: The Gut-Brain-Axis (GBA)

1. The role of the Microbiome

2. The role of the Microbiome–Gut–Brain Axis in opioid use disorder

3. The role of the Microbiome–Gut–Brain Axis in alcohol use disorder

4. The role of the Microbiome–Gut–Brain Axis in neurostimulant use disorder

5. The role of the Microbiome–Gut–Brain Axis in cannabis use disorder

Section 2: The triangle of neurotransmitter systems, intracellular pathways, and neuropsychiatric disorders in the context of addiction

6. Depression

7. Anxiety

8. Schizophrenia

9. Attention deficit hyperactivity disorder (ADHD)

10. Bipolar disorder

11. Post-traumatic stress disorder (PTSD)

12. Obsessive compulsive disorder (OCD)

13. Addiction-associated neurodegenerative disorders

Section 3: The role of modern central dogma of molecular biology-related methods in addiction

14. Multi-OMICS methods

15. Immunotherapies and vaccines

16. Single nucleotide polymorphisms (SNP) methods

17. Implications for CRISPR-Cas9

Product details

  • Edition: 1
  • Latest edition
  • Published: January 1, 2027
  • Language: English

About the editors

MS

Mohammad Shabani

Professor Mohammad Shabani acquired a PhD in 2010 from the Shahid Beheshti University of Medical Sciences. He earned a fellowship training in calcium imaging and intracellular recording at the Copenhagen University (Department of drug design and pharmacology) in 2018. Professor Shabani earned the honor of the full professorship of Kerman Medical University since the second half of 2018. He is an academic member in the Department of Neuroscience in Kerman Neuroscience Research Center (KNRC) (since 2005). He has been the Chair of Research community of KNRC for 8 years. Professor Shabani chaired the intracellular recording lab of KNRC between 2011 and 2023. So far, Professor Shabani has contributed to authoring more than 150 papers in prestigious journals and authoring one book.

Affiliations and expertise
Kerman Medical University, Iran

MB

Mohammad Banazadeh

Dr. Mohammad Banazadeh earned his PharmD. degree from Kerman University of Medical Sciences in 2019. Since then he has been working as a Research Assistant in Kerman Neuroscience Research Center and Pharmaceutical Sciences and Cosmetic Products Research Center. He is enthusiastic of science especially of Neuroscience, which has been his favourite topic since he was young.

Affiliations and expertise
Kerman University of Medical Sciences, Iran

ME

Mohammad Navid Ebrahimi

Dr. Mohammad Navid Ebrahimi completed his PhD in Neuroscience at Kerman Neuroscience Research Center. He has been working as a researcher since his Masters studies in the field of Medical Physiology. He currently serves as an Assistant Professor in the Department of Psychiatry at Kerman University of Medical Sciences, where he also contributes to the Neuroscience Research Center. His main research interests are addiction and cognitive impairments.

Affiliations and expertise
Kerman Neuroscience Research Center, Iran

ST

Silvia Turroni

Prof. Silvia Turroni is an expert in the field of Microbiome-Gut-Brain-Axis and currently serves an Associate Professor of the Department of Pharmacy and Biotechnology in the University of Bologna, Italy.
Affiliations and expertise
Department of Pharmacy and Biotechnology, University of Bologna, Italy