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Elsevier

Antimicrobial Resistance in the 21st Century

Understanding and Combating the Rising Threat

  • 1st Edition - August 27, 2026
  • Latest edition
  • Editors: Dipayan Das, Birson Ingti, Amitabha Bhattacharjee, Payel Paul
  • Language: English

Antimicrobial Resistance in the 21st Century: Understanding and Combating the Rising Threat addresses one of the greatest public health challenges of our time, antibiotic resist… Read more

Description

Antimicrobial Resistance in the 21st Century: Understanding and Combating the Rising Threat addresses one of the greatest public health challenges of our time, antibiotic resistance. This book explores the science, history, and global impact of this crisis, providing readers with the knowledge they need to understand the problem and take necessary action. It meticulously unpacks the genetic, biochemical, and evolutionary mechanisms behind antibiotic resistance, while examining how human behaviors—from healthcare practices to agricultural methods—fuel its spread. It highlights the critical roles of environmental factors, misuse of antibiotics, and gaps in diagnosis and stewardship that exacerbate resistance across both clinical and community settings. It also examines innovative solutions, including next-generation antibiotics, alternative therapies, vaccines, and advances in infection control, alongside the global policy strategies necessary to combat this threat. By addressing the scientific, medical, economic, and sociocultural dimensions of antimicrobial resistance, this book provides a roadmap for coordinated, multidisciplinary efforts to preserve antibiotic efficacy and safeguard public health for future generations. It is written by global experts for researchers and scientists in microbiology, infectious diseases, public health, and pharmacology. It is also of interest to healthcare professionals such as clinicians, pharmacists, and nurses, as well as policymakers, public health officials, students, and industry professionals.

Key features

  • Explains how bacteria develop resistance, the role of overuse and misuse, and why new antibiotics are difficult to develop
  • Covers infection control measures, responsible antibiotic prescribing, and global initiatives
  • Discusses cutting-edge research on alternatives to antibiotics, such as bacteriophage therapy and artificial intelligence–-driven drug discovery

Readership

Researchers and scientists in microbiology, infectious diseases, public health, and pharmacology; Healthcare professionals such as clinicians, pharmacists, and nurses dealing with antibiotic-resistant infections

Table of contents

1. Introduction to Antibiotic Resistance: Mechanisms, Challenges, and Solutions

2. The Science of Resistance: Genetic and Biochemical Mechanisms in Antibiotic Evasion

3. Survival of the Fittest: The Adaptive Evolution of Antibiotic-Resistant Bacteria

4. Fuelling the Resistance: The Impact of Antibiotic Misuse and Overuse

5. Hidden Hotspots: Environmental Drivers of Antibiotic Resistance

6. Hospital Battleground: Addressing Antimicrobial Resistance in Healthcare Settings

7. The Rise of Antibiotic Resistance: Impacts and Solutions in Community Health

8. Tackling Antibiotic Resistance: Challenges in Everyday Environments

9. Navigating the Complexities of Antibiotic Resistance Diagnosis

10. Next-Gen Antibiotics: Breakthroughs in Discovery and Development

11. Beyond Antibiotics: Exploring New Therapies for Resistance Challenges

12. Guarding Health: The Role of Vaccines and Preventative Measures

13. Preserving Efficacy: A Comprehensive Approach to Antimicrobial Stewardship

14. Global Strategies for Antibiotic Governance: Navigating Policy Challenges

15. Navigating Antibiotic Resistance Challenges in Low- and Middle-Income Countries

16. The Antibiotic Dilemma: How the Pharmaceutical Industry Shapes Our Future

17. Farming Under Fire: The Role of Agricultural Practices in Antibiotic Resistance Development

18. Cultural Contexts and Behavioural Patterns: Impacts on Antibiotic Utilisation

19. Revolutionising Safety: Advances in Infection Control and Hygiene Practices

20. The Ripple Effect: Understanding the Economic and Social Consequences of Antibiotic Resistance

21. Target-Centric Drug Repurposing: A Next-Generation Approach to Confront Antimicrobial Resistance

Product details

  • Edition: 1
  • Latest edition
  • Published: August 27, 2026
  • Language: English

About the editors

DD

Dipayan Das

Dr. Dipayan Das, Ph.D., serves as Assistant Professor in the Department of Microbiology and Assistant Dean (Academics) at the Royal School of Biosciences, The Assam Royal Global University. He has over five years of teaching experience at undergraduate and postgraduate levels, complemented by eight years of research experience. Prior to his current position, he was associated with the Centre for Innovative Studies at the University of North Bengal. Dr. Das completed his doctoral research under the supervision of Dr. Palash Mandal in the Department of Botany at the University of North Bengal. His research focuses on the application of nanoparticles for crop improvement, with broader interests spanning nanobiology, microbiology, plant physiology and biochemistry. He is a life member of the Indian Botanical Society and the Microbiologists Society, India. Dr. Das has authored over 50 research papers in international journals and five academic books. His academic achievements include receiving the CSIR-UGC-NET Fellowship, as well as the InSc Young Scientist Award and InSc Research Excellence Award. He secured first rank (Gold Medal) in M.Sc. Botany in 2014 and second rank (Silver Medal) in B.Sc. Botany in 2012 from the University of North Bengal. He has qualified the CSIR-UGC NET five times, along with clearing the West Bengal SET and GATE once each. He was also selected for the DST-INSPIRE Doctoral Fellowship. In addition to his academic and research contributions, Dr. Das has five years of experience mentoring aspirants for the CSIR-UGC NET examination, with many of his students currently pursuing doctoral research across leading institutions in India or serving as faculty members in universities and colleges.

Affiliations and expertise
Assistant Professor, Department of Microbiology and Assistant Dean (Academic Affairs), Royal School of Biosciences, The Assam Royal Global University, Guwahati, India

BI

Birson Ingti

Dr. Birson Ingti is an Assistant Professor & Coordinator (Department of Microbiology) and Assistant Dean (Admissions), The Assam Royal Global University. Dr. Ingti has more than 11 years of Research and 5 years of teaching experience, his expertise lies in antimicrobial resistance, plasmid-mediated β-lactamase genes, and microbial genomics. He has published over 20 research articles in peer-reviewed journals and authored book chapters with Springer and Taylor & Francis. He is a recipient of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Grant and holds ICAR-NET qualification. Dr. Ingti is an active member of ESCMID, BSAC (UK), and ProMED EPICORE. His ongoing research focuses on β-lactamase inhibition using medicinal plant extracts. He has delivered lectures in national and international academic forums.
Affiliations and expertise
Assistant Professor, Dept of Microbiology, The Assam Royal Global University, Guwahati, India

AB

Amitabha Bhattacharjee

Dr. Amitabha Bhattacharjee is an Associate Professor in the Department of Microbiology at Assam University, Silchar. With over 15 years of academic and more than 20 years of research experience, he specializes in antimicrobial resistance, clinical microbiology, and molecular diagnostics. Dr. Bhattacharjee holds a Ph.D. from Banaras Hindu University and has completed prestigious postdoctoral fellowships in the UK and France under DBT and ICMR programs. He has published over 125 research articles and multiple book chapters, and holds 3 Indian patents on antibiotic resistance detection. He has successfully led 14 national and international research projects funded by DBT, CSIR, DST, and others. His notable accolades include the ICMR International Fellowship, DBT-CREST Award, and Asia Pacific Young Investigator Award. A reviewer for leading journals, he has presented his work globally. Dr. Bhattacharjee's research continues to focus on developing diagnostic markers for AMR and exploring genomic mechanisms of resistance in bacterial pathogens.
Affiliations and expertise
Professor, Department of Microbiology, Assam University, Silchar, India

PP

Payel Paul

Dr. Payel Paul is an Assistant Professor in the Department of Botany, North Bengal St. Xavier’s College. Dr. Paul carries 5 years of teaching experience at UG level and 10 years of research experience. Previously Dr. Paul was with the Taxonomy of Angiosperms and Biosystematics Laboratory, Department of Botany, University of North Bengal as a Senior Research Scholar. She works in the field of plant systematics, palynology and molecular systematics. She has published 18 research articles and 4 academic books to date. She holds University of North Bengal first class second position in Masters of Science in Botany for the year 2014 (Silver Medalist). She was a recipient of Post-Graduate Indira Gandhi Scholarship for the period of 2012-2014 and UGC-BSR Fellowship as JRF and SRF for the period of 2015-2020. She's also experienced in conducting Botany practical and examinations of IGNOU.
Affiliations and expertise
Assistant Professor, Department of Botany, North Bengal St. Xavier’s College, Rajganj, India