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Elsevier

Microbiome and Tumorigenesis in Different Cancers

  • 1st Edition - January 1, 2027
  • Latest edition
  • Editors: Sanjana Mehrotra, Vijay Kumar Prajapati
  • Language: English

Microbiome and Tumorigenesis in Different Cancers delves into the intricate relationship between the human microbiome and various health conditions, with a particular focus on can… Read more

Description

Microbiome and Tumorigenesis in Different Cancers delves into the intricate relationship between the human microbiome and various health conditions, with a particular focus on cancer. It is divided into five parts, each addressing a critical aspect of microbiome research and its implications for health and disease. In 4 parts the book provides a foundational understanding of the human microbiome, examines the dual role of the microbiome in cancer development, discusses the role of dysbiosis in gastrointestinal, skin, oral, lung, genitourinary, and hematological malignancies and gives an overview of the methodologies used to study the microbiome. The final part explores the emerging field of pharmacomicrobiomics, focusing on the interaction between the microbiome and cancer therapies. This book serves as a valuable resource for researchers, clinicians, and students interested in understanding the complex interplay between the microbiome and cancer, offering insights into potential therapeutic strategies and future directions in microbiome research.

Key features

  • Offers an in-depth exploration of the human microbiome, including its composition, diversity, and the concept of dysbiosis
  • Is dedicated to understanding how the microbiome influences cancer development, progression, and treatment
  • Includes detailed chapters on the latest methodologies for studying the microbiome, such as high-throughput sequencing, bioinformatics tools, and various profiling techniques
  • Addresses practical aspects like sampling methods and ethical considerations

Readership

Researchers and Academic involved in microbiome research, cancer biology, immunology, molecular biology, and related fields

Table of contents

Part I: About Microbiome and Dysbiosis

1. The Human Microbiome: Conceptual Foundations, Ecological Organization, and Determinants

2. Revisiting Dysbiosis: Concepts, Ecological Principles and Clinical Consequences

3. From Dysbiosis to Tumorigenesis: The Expanding Role of the Microbiome in Cancer Biology

Part II: Microbiome Dysbiosis and Carcinogenesis

4. Microbiome and Innate Immune Responses: Effect on Tumor Immunity

5. Dual Roles of Microbial Metabolites in Cancer: From Oncogenic Drivers to Protective Effectors

6. Role of Fungal and Viral Microbiome Dysbiosis in Human Cancer Development and Treatment

Part III: Dysbiosis in Organ Specific Cancers

7. Microbial Signatures of Gastrointestinal Cancers

8. Skin Microbiota, Skin Health, and the Development of Skin Cancers

9. Microbial Influences on Carcinogenesis: The Role of Oral Microbiota

10. Lung Microbiome and Lung Carcinogenesis

11. Microbiome in head and neck cancer: current and future perspectives

12. Liver microbiome and liver carcinogenesis: a review

13. Microbial Dysbiosis and Gynecologic Malignancies: Focus on the Vaginal Niche

Product details

  • Edition: 1
  • Latest edition
  • Published: January 1, 2027
  • Language: English

About the editors

SM

Sanjana Mehrotra

Dr. Mehrotra has a decade of research experience in the field of genetics of complex disorders like glaucoma, cancer and infectious diseases. Dr. Mehrotra is presently investigating the microbiome dysbiosis in PKDL and oral cancer. She has performed genetic association studies to explore the role of autophagy genes in modifying genetic susceptibility to oral cancer. She uses bioinformatic tools for performing pathway analysis and finding hub genes in different solid tumors that have the potential to be developed as diagnostic and prognostic biomarkers. She has published 24 research articles in peer reviewed international journals and 4 book chapters with reputed publishers. She has published her research work in the prestigious international journals such as the Nature Genetics, Journal of Cellular Physiology, Frontiers in Cellular Infection and Microbiology etc.

Affiliations and expertise
Assistant Professor, Department of Human Genetics, Amritsar, Punjab, India

VP

Vijay Kumar Prajapati

Dr. Vijay Kumar Prajapati is an Associate Professor in the Department of Biochemistry at the University of Delhi South Campus, New Delhi, India. He specializes in cell-death research, parasitology, and therapeutic developments for infectious diseases. He has published extensively in international journals and contributed chapters to reputable publishers. He is a recipient of the INSA Medal for Young Scientist from the Indian National Science Academy and an Associate of the Indian Academy of Sciences, Bengaluru. His work has appeared in leading journals spanning infectious diseases and cellular physiology, reflecting a high scholarly impact and a broad research portfolio.

Affiliations and expertise
Department of Biochemistry, University of Delhi South Campus, India