Enzymes
Biomarkers, Targets and Therapy
- 1st Edition - January 1, 2027
- Latest edition
- Editors: Priyanka Bajaj, Anatampillai Rangraj Satvik Iyenga
- Language: English
Enzymes: Biomarkers, Targets and Therapy examines the critical role of enzymes in drug discovery, diagnostics, and therapeutic applications, providing essential insights for clinic… Read more
Description
Description
Enzymes: Biomarkers, Targets and Therapy examines the critical role of enzymes in drug discovery, diagnostics, and therapeutic applications, providing essential insights for clinicians, biomedical researchers, and pharmaceutical industry professionals. This book highlights the utility of enzymes as biomarkers for disease diagnosis, targets for innovative drug discovery, and therapeutic agents in treating various conditions. Within its comprehensive chapters, the book discusses enzymatic biomarkers in neurodegenerative disorders such as Alzheimer's disease and α-synucleinopathies, where enzymes are pivotal in understanding disease mechanisms and potential interventions. It covers enzymatic drug targets in cancers and diabetes, offering insights into harnessing enzymes for novel therapeutic strategies. Additionally, the book explores the role of enzymes in lipid and hypertensive disorders, emphasizing their potential in managing these conditions. Further, the book examines enzymes as therapeutic agents in autoimmune and infectious diseases, featuring approaches like CRISPR-Cas9 gene editing to tackle antimicrobial resistance. This resource is invaluable for biomedical researchers, neurologists, oncologists, diabetologists, endocrinologists, and pharmaceutical industry researchers aiming to expand their knowledge in enzyme-based therapeutic research. By providing curated information, it equips its audience with the necessary knowledge to explore new directions in drug discovery and enzymatic therapy.
Key features
Key features
- Explains the role of enzymes as biomarkers in disease diagnosis, providing clinicians with essential insights for improved diagnostic strategies
- Discusses enzymes as targets for drug discovery, offering biomedical researchers’ valuable information for advancing therapeutic development
- Evaluates the use of enzymes as therapeutic molecules, guiding pharmaceutical industry researchers in developing enzyme-based treatments
Readership
Readership
Biomedical researchers, neurologists, oncologists, diabetologists, endocrinologists
Table of contents
Table of contents
1. Introduction - Enzymes: Biomarkers, Targets and Therapy
2. Enzymes in α-synucleinopathies: Biomarkers, Targets and Therapeutic molecules
3. Enzymes as Biomarkers, Targets and Therapeutic molecules in Alzheimer’s disease
4. Enzymes of relevance as biomarkers in cancers
5. Enzymatic targets for drug discovery in cancers
6. Enzymes as drug targets in diabetes
7. Enzymes in lipid disorders
8. Enzymes in Hypertensive disorders
9. Enzymatic biomarkers in Cardiovascular Disorders
10. Enzymes as biomarkers and therapeutic targets in Autoimmune Disorders
11. Enzymes for treatment of bacterial diseases
12. Mitigating the antimicrobial resistance through enzymes: The role of CRISPR-Cas9 gene editing
2. Enzymes in α-synucleinopathies: Biomarkers, Targets and Therapeutic molecules
3. Enzymes as Biomarkers, Targets and Therapeutic molecules in Alzheimer’s disease
4. Enzymes of relevance as biomarkers in cancers
5. Enzymatic targets for drug discovery in cancers
6. Enzymes as drug targets in diabetes
7. Enzymes in lipid disorders
8. Enzymes in Hypertensive disorders
9. Enzymatic biomarkers in Cardiovascular Disorders
10. Enzymes as biomarkers and therapeutic targets in Autoimmune Disorders
11. Enzymes for treatment of bacterial diseases
12. Mitigating the antimicrobial resistance through enzymes: The role of CRISPR-Cas9 gene editing
Product details
Product details
- Edition: 1
- Latest edition
- Published: January 1, 2027
- Language: English
About the editors
About the editors
PB
Priyanka Bajaj
Dr. Priyanka Bajaj, PhD, Editor is an Assistant Professor at the Department of Chemical Sciences at the National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India. Her group is working on the cutting-edge field of Biopharmaceutical Proteins and Enzymes. The group explores industrially important biopharmaceutical proteins like antibodies, antibody-drug conjugates (ADCs), and enzymes, including P450s, Ketoreductases, Transaminases, and others. She has 15 years of experience from her two post-doctorates at the University of Rochester, New York, and the University of Michigan, Ann Arbor, MI, USA, as well as in her PhD from NIPER, Mohali. She is the author and co-author of multiple reputed international research articles in reputed journals like Angewandte Chemie, Journal of Organic Chemistry, Biochemie and others and patents and has been awarded several national and international academic awards. She has supervised 15 master students by now and is currently supervising 08 masters and 06 PhD students.
Affiliations and expertise
National Institute of Pharmaceutical Education and Research (NIPER), IndiaAI
Anatampillai Rangraj Satvik Iyenga
Dr. A. R. Satvik Iyengar, PhD, holds a Doctor of Philosophy degree in Medical Biochemistry from The University of Newcastle in Australia. Subsequent to his PhD he worked as a Scientific Writer in Cactus Communications in India. Prior to his PhD he graduated with a Masters in Science in Pharmaceutical Sciences from NIPER, S.A.S. Nagar in India and later worked as Junior Research fellow (JRF) at NIPER, S.A.S. Nagar. During his PhD he worked on understanding the effects of inflammation in Parkinson’s disease and during his MS and JRF tenure he has worked on Enzyme expression, purification and stabilization. He has been involved in writing scientific articles for more than a decade and has published several review and research articles. During his stint as a scientific writer for Cactus Communications he was also involved in writing medical information documents for various pharmaceutical companies that were aimed at informing health care professionals.
Affiliations and expertise
The University of Newcastle, UK