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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Mitochondrial Diseases

    • 1st Edition
    • Volume 194
    • February 20, 2023
    • English
    Mitochondrial Diseases, Volume 194 presents the most common clinical manifestations, providing an up-to-date summaries on the clinical presentations, diagnostic processes, genetic counseling and treatment options in mitochondrial diseases. Contents include specialist biochemical analyses and targeted molecular genetic testing, as well as first-line genome-wide sequencing to accelerate speed of diagnosis while avoiding time-consuming, expensive and invasive investigations. Establishing a genetic diagnosis allows patients with mitochondrial diseases to have reproductive options, all of which are covered within.This book is intended for neurologists to help them recognize and manage patients with mitochondrial diseases.

  • Precision Medicine in Neurodegenerative Disorders

    Part II
    • 1st Edition
    • Volume 193
    • February 16, 2023
    • English
    Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193 in the Handbook of Clinical Neurology deals with the "How" in the reconfiguration of our approach to slow accelerated brain aging. The book rethinks animal models on which therapies are tested, outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology, and the growing role of microbiome in shaping disease. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision "medicine"–matching biology with the mechanism of intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes.

  • Precision Medicine in Neurodegenerative Disorders

    Part I
    • 1st Edition
    • Volume 192
    • February 14, 2023
    • English
    Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-split... tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine.

  • Adolescent Psychosis

    Clinical and Scientific Perspectives
    • 1st Edition
    • February 8, 2023
    • Ingrid Agartz + 1 more
    • English
    Adolescent Psychosis: Clinical and Scientific Perspectives presents new methodologies and novel scientific findings, with a comprehensive orientation into the genetics, phenomenology, nosology, and long-term outcome of adolescent early-onset psychosis research. This volume discusses recent epidemiological studies, along with co-morbid aspects associated with other neurodevelopmental syndromes and somatic diseases. The book also provides suggestions for future research using a translational perspective, from genes to the clinic to and relevant phenotypes, biomarkers, treatment options and etiological aspects. Topics discussed bring together expert researchers in the field to represent different perspectives and future possibilities.

  • Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders

    • 1st Edition
    • Volume 168
    • February 1, 2023
    • English
    Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinson’s disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders.

  • Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

    • 1st Edition
    • January 25, 2023
    • Elena L. Paley
    • English
    Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer’s disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold’s reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book.

  • Tratamiento integral del ictus

    • 7th Edition
    • January 13, 2023
    • James C. Grotta + 7 more
    • Spanish
    Título derivado del libro de referencia internacional sobre el abordaje integral del ictus, Grotta, que recoge todos los temas relacionados con el tratamiento clínico de esta patología excluyendo así toda la parte vinculada al tratamiento quirúrgico. Esta obra incluiría los diferentes enfoques terapéuticos de esta patología recogiendo en su índice un total de 12 capítulos. Considerando que el abordaje del ictus tiene un enfoque totalmente transversal, el objetivo que se persigue con este derivado es que cualquier profesional NO neurólogo tenga a su disposición el contenido esencial para la asistencia de un paciente que ha sufrido un accidente cerebrovascular. Este derivado, al igual que la obra de referencia, está escrito por los mayores expertos de mundo en la materia e incorpora los resultados de las investigaciones más recientes realizadas en cuanto al manejo de la patología. Igualmente, la parte de terapia farmacológica está completamente actualizada incluyendo los últimos hallazgos en esta área.

  • Encyclopedia of Sleep and Circadian Rhythms

    • 2nd Edition
    • January 10, 2023
    • Clete Kushida
    • English
    Encyclopedia of Sleep and Circadian Rhythms, Second Edition, Six Volume Set is the most comprehensive work on sleep and circadian rhythms. This completely revised new edition, comprised of contributions from 450 renowned authorities in the field, covers what is new and known in the field. In addition to thorough coverage of the basics (physiology, sleep disorders etc.), this new edition includes a thorough examination of circadian rhythms that manage the sleep-wake cycle. Although this area is highly intertwined with sleep, it is a scientific discipline in and of itself, and will broaden the appeal of this work to health care providers and scientists. Other sections of interest explore consumer wearable devices to track sleep and circadian rhythms, artificial intelligence algorithms to detect sleep and abnormal sleep-related conditions, and new technology to treat sleep and circadian rhythm disorders. This book will be an ideal and primary reference resource for students, trainees, technologists, basic/clinical scientists, physicians, advanced practice providers, psychologists, nurses, and other medical and research personnel who want to explore any topic within the sleep and circadian rhythm field.

  • Neuropalliative Care

    Part II
    • 1st Edition
    • Volume 191
    • January 3, 2023
    • English
    Neuropalliative Care, Part Two, Volume 191 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.

  • Primer on the Autonomic Nervous System

    • 4th Edition
    • December 7, 2022
    • Italo Biaggioni + 5 more
    • English
    Primer on the Autonomic Nervous System, Fourth Edition provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book's 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored.

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