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Elsevier

Books in Life sciences

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 113
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 113, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic, with this release focusing on Gaps in the Assortment of Rapid Assays for Microorganisms of Interest to the Dairy Industry, Metal reduction and corrosion by bacterial biofilms, The microbiology of red brines, Clostridium thermocellum: a microbial platform for high-value chemical production from lignocellulose, and The zincophore system in pathogenic yeasts.

  • Ketamine for Treatment-Resistant Depression

    Neurobiology and Applications
    • 1st Edition
    • Gustavo H. Vazquez + 2 more
    • English
    Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics.

  • Computational Modeling in Biomedical Engineering and Medical Physics

    • 1st Edition
    • Alexandru Morega + 2 more
    • English
    Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies.

  • Enzyme Engineering and Evolution: Specific Enzyme Applications

    • 1st Edition
    • Volume 644
    • English
    Methods in Enzymology, Volume 644, the latest release in this ongoing serial, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Site-directed recombination (SDR) in vivo: a fast and reliable tool to unveil beneficial epistasis, Creation and application of amine oxidase with expanded substrate specificities from porcine kidney D-amino acid oxidase, Methods to assess correlation networks for engineering transketolase, Exploration of Enzyme Diversity by Integrating Bioinformatics with Microfluidics, Engineering lytic polysaccharide monooxygenases (LPMOs), Emulsion-based directed evolution of enzymes in yeast, and much more.

  • Diabetología

    • 3rd Edition
    • Louis Monnier + 1 more
    • Spanish
    La obra insiste en los aspectos prácticos del abordaje y en los nuevos métodos de exploración, se­guimiento y tratamiento. Las estrategias diagnósticas y terapéuticas novedosas se han desarrollado siguiendo los avances científicos más recientes. Se han incluido cinco capítulos nuevos, sobre los efectos de los tratamientos an­tihiperglucemiant... en las complicaciones cardiovasculares y renales del paciente diabético de tipo 2; la monitorización glucémica continua en las diabetes de tipos 1 y 2; la disbiosis intestinal y las enfermedades metabólicas; las complicaciones he­páticas, y Ramadán y diabetes. Asimismo, se ha profundizado en las nuevas recomendaciones diagnósticas y te­rapéuticas. A ellas se les han dedicado dos capítulos totalmente actualizados: «Ár­boles terapéuticos y de decisión en la diabetes de tipo 2» e «Insulinoterapia en la diabetes de tipos 1 y 2». Práctica y didáctica, esta obra está dirigida al conjunto de los profesionales sanita­rios que tienen que tratar con pacientes diabéticos.

  • Microbial and Natural Macromolecules

    Synthesis and Applications
    • 1st Edition
    • Surajit Das + 1 more
    • English
    Microbial and Natural Macromolecules: Synthesis and Applications brings together active scientists and academicians in the field who share updated information and research outcomes from global experts. Microbial macromolecular diversity, molecular composure, genetics, usability of advanced molecular tools and techniques for their study as well as their applicability are discussed with detailed research perspectives.

  • Microbial Biotechnology in Food and Health

    • 1st Edition
    • Ramesh C. Ray
    • English
    Microbial Biotechnology in Food and Health Science, volume one in the Applied Biotechnology Reviews series, offers two unique sections within the theme of genomics and bioprocessing and the bioengineering of microorganisms in the role of food science and human health. This volume provides review articles as the basis supporting biotechnological research useful to a wide scope of research initiatives. Important relevant information on genomics, proteomics and metabolomics are included as well as the emerging interdisciplinary area of synthetic biology which enables the metabolic engineering of microorganisms to produce pharmaceuticals. Applied Biotechnology Reviews is a series aimed at bringing all aspects of biotechnology as it is applied to food science – from agriculture through product processing into focus through topical volumes. Each volume will cover a relevant application approach in industrial biotechnology.

  • Epigenetics and Reproductive Health

    • 1st Edition
    • Volume 21
    • English
    Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics.

  • Microbial Pesticides

    Biological Resources, Production and Application
    • 1st Edition
    • Vladimir V. Gouli + 2 more
    • English
    Microbial Pesticides: Biological Resources, Production and Application provides a concise and accessible introduction on the history of microbial pesticides, their impact on global ecology, human society and economies, as well as a thorough and tangible description of the state-of-the-art technologies available for the production, application, limitations and long–term viability of these bio-products. Information is listed per biological group (i.e., virus, bacteria, fungi, protozoa, microsporidia and microbial metabolites), and is supported by sound scientific data. The book is copiously illustrated, with original pictures clarifying the most common techniques and protocols utilized in microbiological biocontrol technology. Finally, images of all biological active ingredients currently used in commercially produced formulations, as well as laboratory developed formulations, are illustrated and listed in detailed tables for prompt access.

  • Theory and Applications of Nonparenteral Nanomedicines

    • 1st Edition
    • Prashant Kesharwani + 2 more
    • English
    Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

  • Integrative Pancreatic Intervention Therapy

    A Holistic Approach
    • 1st Edition
    • Maoquan Li + 4 more
    • English
    Integrative Pancreatic Intervention Therapy: A Holistic Approach summarizes, in a systematic manner, the diagnosis and treatment of late, critical pancreatic diseases. The book gives insights into each interventional technique, with an ultimate goal of improving survival rates for late stage pancreatic cancer patients. Six sections cover basic and transformation research on pancreatic diseases, interventional therapy for benign pancreatic disease, interventional therapy for malignant pancreatic diseases, interventional therapy for pancreative cancer-related lesions, stem cell and targeted molecular therapy for pancreative carcinoma, and combined interventional therapy for pancreative carcinoma. This book will be useful for those looking to understand how best to apply interventional therapy for the improvement of late state pancreatic cancer treatment.

  • The Bowhead Whale

    Balaena Mysticetus: Biology and Human Interactions
    • 1st Edition
    • J.C. George + 1 more
    • English
    The Bowhead Whale: Balaena mysticetus: Biology and Human Interactions covers bowhead biology from their anatomy and behavior, to conservation, distribution, ecology and evolution. The book also discusses the biological and physical aspects of the Arctic ecosystem in which these whales live, with careful attention paid to the dramatic changes taking place. A special section of the book describes the interactions of humans with bowheads in past and present, focusing on their importance to Indigenous communities and the challenges regarding entanglement in fishing gear, industrial noise and ship strikes. This volume brings together the knowledge of bowheads in one place for easy reference for scientists that study the species, marine mammal biologists, but, equally important, for everyone who is interested in the Arctic.

  • Human Milk Biochemistry and Infant Formula Manufacturing Technology

    • 2nd Edition
    • Mingruo Guo
    • English
    Human Milk Biochemistry and Infant Formula Manufacturing Technology, Second Edition covers the history of bottle feeding, its advantages and disadvantages when compared with breast-feeding, human milk biochemistry, trends and new developments in infant formula formulation and manufacturing, and best practices in infant formula processing technology and quality control. The book also covers human milk proteomics as a new, separate chapter and provides additional information on infant formula clinical trial guidelines. In addition, the book includes information about the formulation and processing of premature and low birth weight infant formula. This book is sure to be a welcome resource for professionals in the food and infant formula industry, academics and graduate students in fields like nutrition, food sciences, or nursing, nutritionists and health professionals, government officials working in relevant departments, and finally, anyone interested in human milk and infant formula.

  • Nature-Inspired Optimization Algorithms

    • 2nd Edition
    • Xin-She Yang
    • English
    Nature-Inspired Optimization Algorithms, Second Edition provides an introduction to all major nature-inspired algorithms for optimization. The book's unified approach, balancing algorithm introduction, theoretical background and practical implementation, complements extensive literature with case studies to illustrate how these algorithms work. Topics include particle swarm optimization, ant and bee algorithms, simulated annealing, cuckoo search, firefly algorithm, bat algorithm, flower algorithm, harmony search, algorithm analysis, constraint handling, hybrid methods, parameter tuning and control, and multi-objective optimization. This book can serve as an introductory book for graduates, for lecturers in computer science, engineering and natural sciences, and as a source of inspiration for new applications.

  • Introduction to the Constraints-Led Approach

    Application in Football
    • 1st Edition
    • Ben Bell
    • English
    Introduction to the Constraints-Led Approach: Application in Football is a coaching resource football coaches can use to understand key theoretical components of the constraints-led approach. Sections discuss ecological dynamics, perception-action, degrees of freedom and complexity theory. Examples are provided within theoretical chapters to assist readers in their practical application. Over 30 designed practices using the constraints-led approach show readers how the theory translates into practice. These are ordered by the aim of the practice, from in possession, to defensive transition, to out of possession and attacking transition. Currently, there are no books on the market covering the constraints-led approach specific to football. The aim is to make this book accessible to football coaches without the necessity to focus solely on academic theory.

  • Digital Innovations in Healthcare Education and Training

    • 1st Edition
    • Stathis Th Konstantinidis + 2 more
    • English
    Digital Innovations in Healthcare Education and Training discusses and debates the contemporary knowledge on the evolution of digital education, learning and the web and its integration and role within modern healthcare education and training. The book encompasses topics such as healthcare and medical education theories and methodologies, social learning as a formal and informal digital innovation, and the role of semantics in digital education. In addition, it examines how simulation, serious games, and virtual patients change learnings in healthcare, and how learning analytics and big data in healthcare education leads to personalized learning. Online pedagogy principles and applications, participatory educational design and educational technology as health intervention are bridged together to complement this collaborative effort. This book is a valuable resource for a broad audience, both technical and non-technical, including healthcare and medical tutors, health professionals, clinicians, web scientists, engineers, computer scientists and any other relevant professional interested in using and creating digital innovations for healthcare education and training.

  • Case Studies in the Beer Sector

    • 1st Edition
    • Roberta Capitello + 1 more
    • English
    Case Studies in the Beer Sector investigates managerial and marketing dynamics in the beer sector. It explores the relevance of consumer science and its use as a tool for marketing strategies, putting special focus on small craft breweries. The book provides a variety of case studies from several countries to outline the global context within which the beer industry is developing. Real-life examples on how innovation and differentiation strategies affect consumer perceptions of beer are included, along with the relationship among breweries throughout the supply chain. Sections cover business strategy, sustainability, and how breweries are meeting the increasing demand for sustainable production processes. While this book provides a thorough reference for scholars and practitioners who work in the beer sector, it is also ideal for those studying business, agriculture, food engineering, technology, applied marketing and business strategy.

  • The Senses: A Comprehensive Reference

    • 2nd Edition
    • Bernd Fritzsch
    • English
    The Senses: A Comprehensive Reference, Second Edition, Seven Volume Set is a comprehensive reference work covering the range of topics that constitute current knowledge of the neural mechanisms underlying the different senses. This important work provides the most up-to-date, cutting-edge, comprehensive reference combining volumes on all major sensory modalities in one set. Offering 264 chapters from a distinguished team of international experts, The Senses lays out current knowledge on the anatomy, physiology, and molecular biology of sensory organs, in a collection of comprehensive chapters spanning 4 volumes. Topics covered include the perception, psychophysics, and higher order processing of sensory information, as well as disorders and new diagnostic and treatment methods. Written for a wide audience, this reference work provides students, scholars, medical doctors, as well as anyone interested in neuroscience, a comprehensive overview of the knowledge accumulated on the function of sense organs, sensory systems, and how the brain processes sensory input. As with the first edition, contributions from leading scholars from around the world will ensure The Senses offers a truly international portrait of sensory physiology. The set is the definitive reference on sensory neuroscience and provides the ultimate entry point into the review and original literature in Sensory Neuroscience enabling students and scientists to delve into the subject and deepen their knowledge.

  • Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders

    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs.

  • Probiotic and Prebiotics in Foods: Challenges, Innovations and Advances

    • 1st Edition
    • Volume 94
    • English
    The Advances in Food and Nutrition Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • pH-Interfering Agents as Chemosensitizers in Cancer Therapy

    • 1st Edition
    • Volume 10
    • Claudiu T. Supuran + 1 more
    • English
    pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field. Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered.

  • Enzyme Engineering and Evolution: General Methods

    • 1st Edition
    • Volume 643
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Update on Emerging Treatments for Migraine

    • 1st Edition
    • Volume 255
    • English
    Update on Emerging Treatments for Migraine, Volume 255, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • In Situ Molecular Pathology and Co-expression Analyses

    • 2nd Edition
    • Gerard J. Nuovo
    • English
    Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry...

  • Artificial Intelligence in Medicine

    Technical Basis and Clinical Applications
    • 1st Edition
    • Lei Xing + 2 more
    • English
    Artificial Intelligence Medicine: Technical Basis and Clinical Applications presents a comprehensive overview of the field, ranging from its history and technical foundations, to specific clinical applications and finally to prospects. Artificial Intelligence (AI) is expanding across all domains at a breakneck speed. Medicine, with the availability of large multidimensional datasets, lends itself to strong potential advancement with the appropriate harnessing of AI. The integration of AI can occur throughout the continuum of medicine: from basic laboratory discovery to clinical application and healthcare delivery. Integrating AI within medicine has been met with both excitement and scepticism. By understanding how AI works, and developing an appreciation for both limitations and strengths, clinicians can harness its computational power to streamline workflow and improve patient care. It also provides the opportunity to improve upon research methodologies beyond what is currently available using traditional statistical approaches. On the other hand, computers scientists and data analysts can provide solutions, but often lack easy access to clinical insight that may help focus their efforts. This book provides vital background knowledge to help bring these two groups together, and to engage in more streamlined dialogue to yield productive collaborative solutions in the field of medicine.

  • Nano Drug Delivery Strategies for the Treatment of Cancers

    • 1st Edition
    • Awesh K. Yadav + 2 more
    • English
    Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field.

  • Plant Cell Biology

    • 1st Edition
    • Volume 160
    • English
    Plant Cell Biology, volume 160 in "Methods in Cell Biology", includes chapters on modern experimental procedures and applications developed for research in the broad area of plant cell biology. Topics covered in this volume include techniques for imaging and analyzing membrane dynamics and movement across membranes; cell wall composition, structure and mechanics; cytoskeleton dynamics and organization; cell development; ion channel physiology; cell mechanics; and methods related to quantifying cell morphogenesis.

  • Microbiomes and Plant Health

    Panoply and Their Applications
    • 1st Edition
    • Manoj Kumar Solanki + 3 more
    • English
    Microbiomes and Plant Health: Panoply and Their Applications includes the most recent advances in phytobiome research. The book emphasizes the use of modern molecular tools such as smart delivery systems for microbiol inoculation, next-generation sequencing, and genome mapping. Chapters discuss a variety of applications and examples, including the sugarcane microbiome, rhizoengineering, nutrient recycling, sustainable agricultural practices and bio-potential of herbal medicinal plants. Written by a range of experts with real-world practical insights, this title is sure to be an essential read for plant and soil microbiologists, phytopathologists, agronomists, and researchers interested in sustainable forestry and agriculture practices.

  • Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

    • 1st Edition
    • Volume 54
    • English
    The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-us... regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

  • New Perspectives on Early Social-Cognitive Development

    • 1st Edition
    • Volume 254
    • English
    New Perspectives on Early Social-Cognitive Development, Volume 258 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Dynamics of Coordinated Attention, Investigating the Role of Neural Body Maps in Early Social-Cognitive Development: New Insights from Infant MEG and EEG, Motion tracking in developmental research: Methodological considerations and social-cognitive developmental applications, Early maturation of the social brain: How brain development provides a platform for the acquisition of social-cognitive competence, Getting a grip on early intention understanding: The role of motor, cognitive, and social factors, and much more.

  • Actin Cytoskeleton in Cancer Progression and Metastasis - Part A

    • 1st Edition
    • Volume 355
    • English
    Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, Volume 355 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.

  • Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases

    • 1st Edition
    • Volume 155
    • English
    Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain – A Role in Type 2 Diabetes Mellitus and Alzheimer’s disease; and much more.

  • Self-assessment Q&A in Clinical Laboratory Science, III

    • 1st Edition
    • Alan H.B. Wu
    • English
    Self-assessment Q&A in Clinical Laboratory Science, III, adds a variety of subject matter that addresses new concepts and emerging technology, particularly in the areas of kidney biomarkers, cancer biomarkers, molecular diagnostics, multiple myeloma, pharmacogenomics, novel cardiovascular biomarkers and biomarkers of neurologic diseases. The field of Clinical Laboratory Science continues to evolve and editor Alan Wu has once again brought together experts in the field to cover the contemporary topics that are being tested today. This updated bank of questions and answers is a must-have to sharpen knowledge and skills.

  • Systems Medicine

    Integrative, Qualitative and Computational Approaches
    • 1st Edition
    • Olaf Wolkenhauer
    • English
    Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice.

  • The Stem Cell Niche during Ageing

    • 1st Edition
    • Volume 4
    • Susie Nilsson
    • English
    Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice.

  • Case Studies on Food Experiences in Marketing, Retail, and Events

    • 1st Edition
    • Susanne Doppler + 1 more
    • English
    Case Studies on Food Experiences in Marketing, Retail, and Events explores approaches for creating ideal food shopping and consumption experiences, and the challenges food customers face today. With a basis in literature review and theoretical background, the book illustrates specific case studies on food shopping experiences, food consumption experience in restaurants, and food experience and events, as well as insights on the methodological tools adopted throughout. Topics include food and food service design, the creation of customer loyalty through experiences, communication strategies like food promotion and event management, and defining product positioning in a competitive environment. This book is an excellent resource for industry professionals in the food and beverage sectors, including those who work in marketing, communication, hospitality, and management, as well as students studying business management, tourism management, event management, applied marketing, and consumer behavior.

  • Histone Modifications in Therapy

    • 1st Edition
    • Volume 20
    • Pedro Castelo-Branco + 1 more
    • English
    Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and inflammatory disorders, among others. In relation to these disease types, histone modifications are discussed, both as mechanisms of prevention and possible treatment. A concluding chapter brings together future perspectives for targeting histone modifications in therapy and next steps in research.

  • Biomaterials for 3D Tumor Modeling

    • 1st Edition
    • Subhas C. Kundu + 1 more
    • English
    Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine.

  • Asian Noodle Manufacturing

    Ingredients, Technology, and Quality
    • 1st Edition
    • Gary G. Hou
    • English
    Asian Noodle Manufacturing: Ingredients, Technology, and Quality is a comprehensive handbook for the manufacture of noodles that includes traditional styles and gluten free and whole grain varieties. The book is split into three main sections, with the first detailing the ingredients in noodles and information on how ingredient functionality affects their processing. The second section details the actual manufacture and quality assurance in producing noodle products, with the final section detailing advances in varieties of noodles. Particular attention is paid to gluten free and whole grain noodles, both of which are becoming increasingly popular around the world. Written by an expert with over twenty years of experience in the production and quality assurance of noodles, the book is essential reading for those in the food industry who are tasked with the development of new noodle based products.

  • Odorant Binding and Chemosensory Proteins

    • 1st Edition
    • Volume 642
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Present and Future of High Pressure Processing

    A Tool for Developing Innovative, Sustainable, Safe and Healthy Foods
    • 1st Edition
    • Francisco J. Barba + 3 more
    • English
    Developed for academic researchers and for those who work in industry, Present and Future of High Pressure Processing: A Tool for Developing Innovative, Sustainable, Safe, and Healthy Foods outlines innovative applications derived from the use of high-pressure processing, beyond microbial inactivation. This content is especially important for product developers as it includes technological, physicochemical, and nutritional perspectives.This book specifically focuses on innovative high-pressure processing applications and begins with an introduction followed by a section on the impact of high-pressure processing on bioactive compounds and bioaccessibility/bio... The third section addresses the ways in which high-pressure processing can assist in the reduction of toxins and contaminants, while the fourth section presents opportunities for the use of high-pressure processing in the development of healthy and/or functional food. This reference concludes with an analysis of the challenges regarding the use of high-pressure processing as an innovative application.

  • Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics

    • 1st Edition
    • Allan Matte
    • English
    Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book.

  • Emerging Technologies for Heart Diseases

    Volume 2: Treatments for Myocardial Ischemia and Arrhythmias
    • 1st Edition
    • Udi Nussinovitch
    • English
    The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options.

  • Emerging Technologies for Heart Diseases

    Volume 1: Treatments for Heart Failure and Valvular Disorders
    • 1st Edition
    • Udi Nussinovitch
    • English
    The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options.

  • RNA-Based Regulation in Human Health and Disease

    • 1st Edition
    • English
    RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics.

  • The Future of Pharmaceutical Product Development and Research

    • 1st Edition
    • English
    The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals... and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries.

  • Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B

    • 1st Edition
    • Volume 174
    • English
    Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B, represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.

  • Swarm Intelligence for Resource Management in Internet of Things

    • 1st Edition
    • Aboul Ella Hassanien + 1 more
    • English
    Internet of Things (IoT) is a new platform of various physical objects or “things” equipped with sensors, electronics, smart devices, software, and network connections. IoT represents a new revolution of the Internet network which is driven by the recent advances of technologies such as sensor networks (wearable and implantable), mobile devices, networking, and cloud computing technologies. IoT permits these the smart devices to collect, store and analyze the collected data with limited storage and processing capacities. Swarm Intelligence for Resource Management in the Internet of Things presents a new approach in Artificial Intelligence that can be used for resources management in IoT, which is considered a critical issue for this network. The authors demonstrate these resource management applications using swarm intelligence techniques. Currently, IoT can be used in many important applications which include healthcare, smart cities, smart homes, smart hospitals, environment monitoring, and video surveillance. IoT devices cannot perform complex on-site data processing due to their limited battery and processing. However, the major processing unit of an application can be transmitted to other nodes, which are more powerful in terms of storage and processing. By applying swarm intelligence algorithms for IoT devices, we can provide major advantages for energy saving in IoT devices. Swarm Intelligence for Resource Management in the Internet of Things shows the reader how to overcome the problems and challenges of creating and implementing swarm intelligence algorithms for each application

  • Storing Digital Binary Data in Cellular DNA

    The New Paradigm
    • 1st Edition
    • Rocky Termanini
    • English
    Storing Digital Binary Data into Cellular DNA demonstrates how current digital information storage systems have short longevity and limited capacity, also pointing out that their production and consumption of data exceeds supply. Author Rocky Termanini explains the DNA system and how it encodes vast amounts of data, then presents information on the emergence of DNA as a storage technology for the ever-growing stream of data being produced and consumed. The book will be of interest to a range of readers looking to understand this game-changing technology, including researchers in computer science, biomedical engineers, geneticists, physicians, clinicians, law enforcement and cybersecurity experts.

  • Innovative Food Processing Technologies

    A Comprehensive Review
    • 1st Edition
    • Kasiviswanathan Muthukumarappan + 1 more
    • English
    Food process engineering, a branch of both food science and chemical engineering, has evolved over the years since its inception and still is a rapidly changing discipline. While traditionally the main objective of food process engineering was preservation and stabilization, the focus today has shifted to enhance health aspects, flavour and taste, nutrition, sustainable production, food security and also to ensure more diversity for the increasing demand of consumers. The food industry is becoming increasingly competitive and dynamic, and strives to develop high quality, freshly prepared food products. To achieve this objective, food manufacturers are today presented with a growing array of new technologies that have the potential to improve, or replace, conventional processing technologies, to deliver higher quality and better consumer targeted food products, which meet many, if not all, of the demands of the modern consumer. These new, or innovative, technologies are in various stages of development, including some still at the R&D stage, and others that have been commercialised as alternatives to conventional processing technologies. Food process engineering comprises a series of unit operations traditionally applied in the food industry. One major component of these operations relates to the application of heat, directly or indirectly, to provide foods free from pathogenic microorganisms, but also to enhance or intensify other processes, such as extraction, separation or modification of components. The last three decades have also witnessed the advent and adaptation of several operations, processes, and techniques aimed at producing high quality foods, with minimum alteration of sensory and nutritive properties. Some of these innovative technologies have significantly reduced the thermal component in food processing, offering alternative nonthermal methods. Food Processing Technologies: A Comprehensive Review, Three Volume Set covers the latest advances in innovative and nonthermal processing, such as high pressure, pulsed electric fields, radiofrequency, high intensity pulsed light, ultrasound, irradiation and new hurdle technology. Each section will have an introductory article covering the basic principles and applications of each technology, and in-depth articles covering the currently available equipment (and/or the current state of development), food quality and safety, application to various sectors, food laws and regulations, consumer acceptance, advancements and future scope. It will also contain case studies and examples to illustrate state-of-the-art applications. Each section will serve as an excellent reference to food industry professionals involved in the processing of a wide range of food categories, e.g., meat, seafood, beverage, dairy, eggs, fruits and vegetable products, spices, herbs among others.

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