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Stress: Genetics, Epigenetics and Genomics

Volume 4: Handbook of Stress

1st Edition - October 22, 2020

Editor: George Fink

Hardback ISBN:

9 7 8 - 0 - 1 2 - 8 1 3 1 5 6 - 5

eBook ISBN:

9 7 8 - 0 - 1 2 - 8 1 3 1 5 7 - 2

This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the… Read more

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This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases.The Handbook of Stress series, comprised of self-contained volumes that each focus on a specific stress area, covers the significant advances made since the publication of Elsevier’s Encyclopedia of Stress (2000 and 2007). Volume 4 is ideal for graduate students, post-doctoral fellows, faculty and clinicians interested in stress genetics, epigenetics and genomics involved in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry and the social sciences

1. Genetic Dissection of Neuropeptide Circuits Mediating Psychosocial Stress
YAIR J. BEN-EFRAIM AND ALON CHEN

2. Genetic Variation of HPA Axis Activity and Function in Farm Animals
PIERRE MORMEDE AND ELENA TERENINA

3. MicroRNAs and the Response to Stress
SHARON L. HOLLINS AND MURRAY J. CAIRNS

4. Stress-Mediated Regulation of the DNA Methylome
ALEC LINDSAY WARD DICK AND ALON CHEN

5. Genomics and Epigenetics of Plant Abiotic Stress
SUPRASANNA PENNA, POOJA NEGI, AND VINAY KUMAR

6. The Long-Term Biological and Clinical Consequences of Child Abuse and Neglect
JONATHAN PARKER AND CHARLES B. NEMEROFF

7. Transcriptional and Epigenetic Regulation of the Corticotropin-Releasing Hormone System and Genetic Associations With Neuropsychiatric Disorders
JAN M. DEUSSING

8. Circadian Clocks, Stress, and Psychiatric Disorders
CHARLOTTE KLING AND DOMINIC LANDGRAF

9. Effects of Psychological Stress on Telomeres as Genome Regulators
LAURA C. ETZEL AND IDAN SHALEV

10. From Exaptation to Adaptation: Stress, Transposons, and Functions of the Deep Genome
ANDREW A. BARTLETT AND RICHARD G. HUNTER

11. Fetal Alcohol Exposure Impairs the Function of Hypothalamic Proopiomelanocortin Neurons via a Circadian Mechanism
DIPAK K. SARKAR

12. Molecular Signaling in the Gut–Brain Axis in Stress
AMANDA J. PAGE AND HUI LI

13. Stress Responsiveness of BDNF/TrkB Signaling in the Neuroendocrine System and Future Implications
I. AZOGU-SEPE AND H. PLAMONDON

14. Estradiol Protects Hypothalamic Neurons Against Insulin Resistance
OLINE K. RØNNEKLEIV AND MARTIN J. KELLY

15. Genetics of Stress Responsiveness
YVETTE M. WILSON, JENNY M. GUNNERSEN, AND MARK MURPHY

16. miRNAs of Astrocyte-Derived Small Extracellular Vesicles Potentially Modulate Adult Neurogenesis Under Stress Conditions
FELIPE BUSTAMANTE, MAXS M_ENDEZ-RUETTE, URSULA WYNEKEN, LUIS FEDERICO BA´ TIZ, AND ROBERTO HENZI

17. Gonadotropin-Releasing Hormone (GnRH) and Corticotropin-Releasing Factor (CRF): An Evolutionary History of Interaction
DAVID A. LOVEJOY AND DAVID W. HOGG

18. New Vistas of Old Terrains: Magnocellular Vasopressin and the Neuroendocrine Response to Stress
FERENC A. ANTONI

19. Responding to Stress: Genomic and Nongenomic Actions of Corticosteroid Receptors in the Brain
SAMANTHA N. HAQUE, KAREN R. MIFSUD, EMILY M. PRICE, AND JOHANNES M.H.M. REUL

20. Mutations of the Human Mineralocorticoid Receptor and Targeted Deletion in Model Organisms
TIMOTHY J. COLE, PETER J. FULLER, AND MORAG J. YOUNG

21. Mechanisms Regulating Hypoxia Tolerance in Drosophila and Humans
DAN ZHOU, PRITI AZAD, TSERING STOBDAN, AND GABRIEL G. HADDAD

22. Brain-Derived Neurotrophic Factor and Its Role in Stress-Related Disorders
MICHAEL NOTARAS AND MAARTEN VAN DEN BUUSE

23. Zebrafish Models for Stress Research
MURILO S. DE ABREU, KONSTANTIN A. DEMIN, TAMARA G. AMSTISLAVSKAYA, TATYANA STREKALOVA, AND ALLAN V. KALUEFF

24. Epigenetic Effects of Exercise on Human Skeletal Muscle
MACSUE JACQUES, SHANIE LANDEN, ANDREW S. PALMER, AND NIR EYNON

25. Exercise and/or Stress Effects on the Epigenetic Clock
SARAH VOISIN

26. Telomeres and Early-Life Stress
STEFANIE MAYER, QUINN CONKLIN, SAMUEL J. RIDOUT, AND KATHRYN K. RIDOUT

27. Molecular Responses to Heat Stress in Escherichia coli
XU-TING WANG, SHI-DI XIAO, AND BIN-GUANG MA

28. Epigenetics and the Impact of Early-Life Stress Across Generations
GRETCHEN VAN STEENWYK AND ISABELLE M. MANSUY

29. Corticolimbic Circuitry and Genomic Risk for Stress-Related Psychopathology
SARAH E. PAUL, NOURHAN M. ELSAYED, ERIN BONDY, AND RYAN BOGDAN

George Fink

Dr. Fink is Honorary Professor in the University of Melbourne and Professorial Research Fellow at the Florey Institute of Neuroscience and Mental Health. Formerly, he was Scientific Director of the Mental Health Research Institute, Melbourne, Australia. Before returning to Melbourne in 2003, Dr. Fink was University Lecturer in Human Anatomy and Fellow in Physiology and Medicine at Brasenose College and the University of Oxford and served for nearly 20 years as CEO and Director of the UK Medical Research Council’s Brain Metabolism Unit in Edinburgh. He gained distinction through his seminal research discoveries in neuroendocrinology and psychopharmacology published in over 360 scientific papers. Dr. Fink served as President of the European Neuroendocrine Association. His distinctions include Fellow of the Royal Society of Edinburgh, Fellow of the Royal College of Physicians of Edinburgh, Fellow of the Royal Biological Society, Fellow of the Physiological Society, and Honorary Member of the British Society for Neuroendocrinology. Fink was Honorary Professor in the University of Edinburgh, delivered the inaugural Geoffrey Harris Prize Lecture of the British Physiological Society, and the Wolfson Lecture. In 1979 he was awarded the Royal Society - Israel Academy Exchange Fellowship which enabled him to spend a research year at the Weizmann Institute of Science, Rehovot Israel. In 2000 he was awarded the Lifetime Achievement Award of the International Society of Psychoneuroendocrinology. His membership of learned societies includes Emeritus member of the Society for Neuroscience, the Endocrine Society and the Genetics Society of America. Dr. Fink has edited several scientific books with Elsevier, including Stress Science: Neuroendocrinology (2009), Stress Consequences: Mental, Neuropsychological and Socioeconomic (2009), Stress of War, Conflict and Disaster (2010), the Handbook of Neuroendocrinology (2011), and most notably the 4-volume second edition of the Encyclopedia of Stress (2007) on which this new Handbook of Stress series is based. He was founding Editor-in-Chief of the first edition of the Encyclopedia of Stress (2000) which was awarded the 2001 British Medical Association commendation for its contribution to Mental Health. The first volume of his Handbook of Stress series, entitled “Stress: Concepts, Cognition, Emotion, and Behavior”, received the BMA High Commendation in the Health and Social Care category as one of the top titles in its discipline.

Affiliations and expertise

Professorial Research Fellow and Hon Professor, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia