
Virus Assembly and Exit Pathways
- 1st Edition, Volume 108 - October 24, 2020
- Imprint: Academic Press
- Editors: Margaret Kielian, Thomas Mettenleiter, Marilyn J. Roossinck
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 0 7 6 1 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 0 7 6 2 - 8
Advances in Virus Research, Volume 108, in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics includ… Read more

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- Presents the latest release in the Advances in Virus Research series
- Includes the latest information on virus assembly and exit pathways
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter One: Geminivirus structure and assembly
- Abstract
- 1: Introduction
- 2: Geminivirus structures
- 3: Host and vector organelles important for capsid transport and gene expression
- 4: Environmental pH and capsid assembly
- 5: Methods of geminivirus control
- 6: Summary
- Chapter Two: Structure-guided paradigm shifts in flavivirus assembly and maturation mechanisms
- Abstract
- 1: Introduction
- 2: Flavivirus polyprotein translation and processing
- 3: Flavivirus structural proteins: Structure and function
- 4: Flavivirus assembly and budding
- 5: Flavivirus maturation and egress
- 6: Conclusions
- Acknowledgments
- Funding
- Chapter Three: Viral cell-to-cell spread: Conventional and non-conventional ways
- Abstract
- 1: Introduction
- 2: Modes of cell-to-cell spread
- 3: Advantages of direct cell-to-cell spread
- 4: Experimental approaches for studying cell-to-cell spread
- 5: Concluding remarks
- Acknowledgments
- Chapter Four: Structure and assembly of archaeal viruses
- Abstract
- 1: Introduction: Diversity of archaeal viruses
- 2: Assembly of head-tailed archaeal viruses
- 3: Assembly of tailless icosahedral viruses
- 4: Assembly of filamentous viruses
- 5: Assembly of spindle-shaped viruses
- 6: Conclusions
- Acknowledgments
- Chapter Five: Potyviral coat protein and genomic RNA: A striking partnership leading virion assembly and more
- Abstract
- 1: Introduction
- 2: Unlocking the smart structure of potyviral capsids
- 3: To assemble, or to disassemble, that is the question
- 4: CP and RNA encapsidation, stuck in the middle of infection
- 5: Potyviral capsids as biotechnological tools, an increasingly promising future
- 6: And now what?
- Acknowledgments
- Chapter Six: Structure and assembly of double-stranded RNA mycoviruses
- Abstract
- 1: Introduction
- 2: Lineage of dsRNA viruses
- 3: Structure of dsRNA mycovirus capsids
- 4: Assembly of dsRNA mycoviruses
- 5: Mycovirus capsids as nanomachines for RNA synthesis
- 6: Evolutionary relationships among dsRNA mycoviruses
- 7: Additional functions of mycovirus capsids
- 8: Conclusions and perspectives
- Acknowledgments
- Chapter Seven: Bluetongue virus assembly and exit pathways
- Abstract
- 1: Introduction
- 2: Assembly pathway of core components
- 3: Interactions between core and outer capsid proteins
- 4: Virion egress pathway
- 5: Conclusion
- Chapter Eight: Current capsid assembly models of icosahedral nucleocytoviricota viruses
- Abstract
- 1: The nucleocytoplasmic large DNA viruses (NCLDVs)
- 2: The double jelly roll and the nucleocytoviricota viruses (NCVs)
- 3: The structure of icosahedral NCVs
- 4: The triangulation numbers of the icosahedral NCV capsids
- 5: Viral factory and NCV assembly
- 6: The current models in the capsid assembly of NCVs
- 7: The tape measure proteins (TmPs) on icosahedral NCV capsid assembly
- 8: A refined assembly model for giant virus capsids
- 9: Conclusion
- Acknowledgments
- Funding
- Chapter Nine: Quasi-enveloped hepatitis virus assembly and release
- Abstract
- 1: Introduction
- 2: Quasi-enveloped HAV assembly and release
- 3: Quasi-enveloped HEV assembly and release
- 4: Unanswered questions and future directions
- Acknowledgments
- Chapter Ten: Betaherpesvirus assembly and egress: Recent advances illuminate the path
- Abstract
- 1: Introduction
- 2: Overview
- 3: Viral interactions with and modification of host systems
- 4: Betaherpesvirus virion assembly and egress
- 5: Final perspective
- Edition: 1
- Volume: 108
- Published: October 24, 2020
- Imprint: Academic Press
- No. of pages: 404
- Language: English
- Hardback ISBN: 9780128207611
- eBook ISBN: 9780128207628
MK
Margaret Kielian
TM
Thomas Mettenleiter
Nationality: German
1963-1967: Elementary School
1967-1976: High School (Gymnasium)
1976: Diploma (Abitur)
1976-1977: Compulsory Military Service
1977-1982: Study of biology at Tuebingen University, Germany
1982-1985: Ph.D. work at Federal Research Centre for Virus Diseases of Animals,
Tuebingen, Germany
1985: Ph.D. in Genetics
1986-1987: Postdoctoral Fellow at Vanderbilt University, Nashville, TN
Department of Microbiology
1988-today: Federal Research Centre for Virus Diseases of Animals
1990: Habilitation (prerequisite for professorship)
since 1994: Director of the Institute of Molecular Biology at the Federal Research Centre for Virus Diseases of Animals, Insel Riems, Germany
since 1996: President of the Federal Research Centre for Virus Diseases of Animals (renamed in 2004 'Friedrich-Loeffler-Institut')
since 1997: Professor of Virology at University of Greifswald
Scientific Work:
More than 300 peer-reviewed publications in international journals (listed in PubMed) on different aspects of infectious animal diseases.
MR