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Elsevier

Books in Life sciences

  • Osteobiographies

    The Discovery, Interpretation and Repatriation of Human Remains
    • 1st Edition
    • Susan Pfeiffer
    • English
    Osteobiographies: The Discovery, Interpretation and Repatriation of Human Remains contextualizes repatriation, or the transfer of authority for human skeletal remains from the perspective of bioarchaelogists and evolutionary biologists. It approaches repatriation from a global perspective, touching upon the most well-known Native American Graves Protection and Repatriation Act (NAGPRA) legislation of the United States, while also covering Canada and African countries. The book focuses on the stories behind human skeletons, analyzing their biological factors to determine evolution patterns. Sections present an overview of anatomy, genomics, and stable isotopes from dietary and environmental factors, and how to identify these in skeletal remains. The book then goes on to discuss European-origin, North American, and African paleopathology, ancient DNA links, and cultural issues and implications around repatriation. It concludes with case studies to show how information from archaeologically derived skeletons is vital to understanding human evolution and provide respectful histories behind the remains.

  • Climate Change and Crop Stress

    Molecules to Ecosystems
    • 1st Edition
    • Arun K.Shanker + 3 more
    • English
    Climate Change and Crop Stress: Molecules to Ecosystems expounds on the transitional period where science has progressed to ‘post-genomics’ and the gene editing era, putting field performance of crops to the forefront and challenging the production of practical applicability vs. theoretical possibility. Researchers have concentrated efforts on the effects of environmental stress conditions such as drought, heat, salinity, cold, or pathogen infection which can have a devastating impact on plant growth and yield. Designed to deliver information to combat stress both in isolation and through simultaneous crop stresses, this edited compilation provides a comprehensive view on the challenges and impacts of simultaneous stresses.

  • Cation Transporters in Plants

    • 1st Edition
    • Santosh Kumar Upadhyay
    • English
    Cation Transporters in Plants presents expert information on the major cation transporters, along with developments of various new strategies to cope with the adverse effects of abiotic and biotic stresses. The book will serve as a very important repository for the scientist, researcher, academician and industrialist to enhance their knowledge about cation transport in plants. Further, applications listed in the book will facilitate future developments in crop designing strategies. This comprehensive resource provides an alternative strategy for abiotic and biotic stress management in agricultural and horticultural crops. In addition, it will further improve basic knowledge om the origin and mechanism of cation homeostasis and their role in developmental transition and stress regulation.

  • Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU

    • 1st Edition
    • Gianni Dal Negro + 1 more
    • English
    Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU provides updated information on the EU Directive 2010/63/EU, which is the European Union legislation that protects animals being used in research. EU Directive 2010/63/EU is the European Union (EU) legislation 'on the protection of animals used for scientific purposes' and is one of the most stringent ethical and welfare standards worldwide.

  • Chemoarchitectonic Atlas of the Rat Brain

    • 3rd Edition
    • George Paxinos + 3 more
    • English
    The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains.

  • Human Growth and Development

    • 3rd Edition
    • Noel Cameron + 1 more
    • English
    Human Growth and Development, Third Edition provides a comprehensive volume covering the biology of human growth and the genetic, endocrine, environmental, nutritional, and socio-economic factors that contribute towards its full expression. Human Growth and Development continues to be a valuable resource for researchers, professors and graduate students across the interdisciplinary area of human development. For the new edition, updates are made to all fourteen of the "core chapters" of the book which form the essential reading for a comprehensive understanding of human growth and development. Additionally, new special topics are covered including the interpretation of recently found sub-adult fossils that expand our understanding of the evolution of human growth and a discussion of the early pattern of growth and development as the developmental origins of risk for non-communicable diseases of adulthood. Human Growth and Development, Third Edition includes contributions from the well-known experts in the field and is the most reputable, comprehensive resource available.

  • Bioactive Food Components Activity in Mechanistic Approach

    • 1st Edition
    • Cinthia Bau Betim Cazarin + 3 more
    • English
    Bioactive Food Components Activity in Mechanistic Approach presents the role of functional foods and bioactive compounds in inflammation. This book focuses on bioactive compounds, including phenolics, prebiotics, carotenoids, tocopherols, bioactive peptides, probiotics, polyunsaturated and monounsaturated fatty acids, and describes their actions in several diseases, mainly obesity and co-morbidities, inflammatory bowel disease, cognitive decline and cancer, and aging. Intended for food, nutrition, and nutraceutical researchers, as well as those studying related fields, the book offers a mechanistic approach that is currently lacking in the market.

  • Sound Communication in Insects

    • 1st Edition
    • Volume 61
    • Russell Jurenka
    • English
    Advances in Insect Physiology, Volume 61 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acoustic signaling in Orthoptera, Sound production in Drosophila melanogaster, and Communication by surface borne mechanical waves in insects.

  • Coronaviruses and other Novel Antiviral Targets

    • 1st Edition
    • Volume 57
    • English
    Annual Reports in Medicinal Chemistry, Volume 57 in this long-running series, highlights new advances in the field with this new volume presenting interesting chapters on the Mechanism of action of the broadly acting antiviral drug remdesivir, Improving properties of the nucleobase analogue T-706 as a potential anti-SARS-CoV-2 and anti-influenza compound, Antivirals for RNA virus infections Anno 2020-2021, Broad spectrum antiviral fleximer nucleosides, SARS-CoV-2 main protease inhibitors, The search for antivirals to treat alphavirus infections, Inhibitors of Ebola Virus targeting Innate immune evasion, Uracil derivatives as non-nucleoside inhibitors of viral infections, and more.

  • Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care

    • 1st Edition
    • Hemanshu Prabhakar
    • English
    The current practice of medicine is largely moving toward applying an evidence-based approach. Evidence-based medicine is the integration of best research evidence using systematic reviews of the medical literature and then translating it into practice by selecting treatment options for specific cases based on the best research. Clinicians rely on the availability of evidence and accordingly take decisions to provide best treatment to their patients. Clinical management of neurologically compromised patients is challenging and varied; for this reason, treating physicians including neuroanesthesiologis... are always in search of best available evidence for patient management and care. Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care highlights the various controversies that exist in the practice of neuroanesthesia and provides conclusive evidence-based solutions. This comprehensive resource succinctly discusses evidence-based practice of neuroanesthesia based on systematic reviews in clinical neuroscience research. Topics include neurophysiology: ICP or CPP thresholds; neuropharmacology: intravenous or inhalational anesthetics; and neuromonitoring: ICP monitoring. Evidence-based practice is now an integral part of neuroscience, and this book will help residents and trainees gain knowledge to apply it to their practice. Endorsements/Reviews... "Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." -- Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC)

  • Advanced Neuro MR Techniques and Applications

    • 1st Edition
    • Volume 4
    • In-Young Choi + 1 more
    • English
    Advanced Neuro MR Techniques and Applications gives detailed knowledge of emerging neuro MR techniques and their specific clinical and neuroscience applications, showing their pros and cons over conventional and currently available advanced techniques. The book identifies the best available data acquisition, processing, reconstruction and analysis strategies and methods that can be utilized in clinical and neuroscience research. It is an ideal reference for MR scientists and engineers who develop MR technologies and/or support clinical and neuroscience research and for high-end users who utilize neuro MR techniques in their research, including clinicians, neuroscientists and psychologists. Trainees such as postdoctoral fellows, PhD and MD/PhD students, residents and fellows using or considering the use of neuro MR technologies will also be interested in this book.

  • Biopesticides

    Volume 2: Advances in Bio-inoculants
    • 1st Edition
    • Amitava Rakshit + 7 more
    • English
    Biopesticide: Volume Two, the latest release in the Advances in Bioinoculant series, provides an updated overview on the active substances utilized in current bioinsecticides, along with information on which of them can be used for integrated pest management programs in agro-ecosystems. The book presents a comprehensive look at the development of novel solutions against new targets, also introducing new technologies that enhance the efficacy of already available active substances. Finally, readers will find insights into the advanced molecular studies on insect microbial community diversity that are opening new frontiers in the development of innovative pest management strategies. This book will be valuable to those prioritizing agro biodiversity management to address optimal productizing and enhanced food security.

  • Understanding Insulin and Insulin Resistance

    • 1st Edition
    • Anil Gupta
    • English
    Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.

  • Advances in Genetics

    • 1st Edition
    • Volume 108
    • Dhavendra Kumar
    • English
    Advances in Genetics, Volume 108 provides the latest information on genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, with this new release including chapters on Clinical applications of cancer genetics and genomics, Epigenetic mutations in childhood tumors- the paradigm of Wilms tumor, Preventive population genomics-the model of BRCA related cancers, Recent advances of PARP inhibitors in medical oncology, Role of single cell and liquid biopsy in cancer research and clinical applications. Other chapters cover Recent advances and clinical utility of prostate cancer genomics, Recent advances in lung cancer genomics- applications in targeted therapy, and more.

  • Year One of Practice Transition

    The Necessary Guide to Success
    • 1st Edition
    • Jason E. Pope + 1 more
    • English
    Year One of Practice Transition: The Necessary Guide to Success is a practical guide for both established physicians transitioning from one practice opportunity to another, and those transitioning from formal residency or fellowship training. This book is an up-to-date look at how to achieve a successful practice, offering insights from top experts who have navigated transition through various phases and circumstances.

  • Wearable Telemedicine Technology for the Healthcare Industry

    Product Design and Development
    • 1st Edition
    • Deepak Gupta + 3 more
    • English
    Wearable Telemedicine Technology for the Healthcare Industry: Product Design and Development focuses on recent advances and benefits of wearable telemedicine techniques for remote health monitoring and prevention of chronic conditions, providing real time feedback and help with rehabilitation and biomedical applications. Readers will learn about various techniques used by software engineers, computer scientists and biomedical engineers to apply intelligent systems, artificial intelligence, machine learning, virtual reality and augmented reality to gather, transmit, analyze and deliver real-time clinical and biological data to clinicians, patients and researchers. Wearable telemedicine technology is currently establishing its place with large-scale impact in many healthcare sectors because information about patient health conditions can be gathered anytime and anywhere outside of traditional clinical settings, hence saving time, money and even lives.

  • Plant Factory Basics, Applications and Advances

    • 1st Edition
    • Toyoki Kozai + 2 more
    • English
    Plant Factory Basics, Applications, and Advances takes the reader from an overview of the need for and potential of plant factories with artificial lighting (PFALs) in enhancing food production and security to the latest advances and benefits of this agriculture environment. Edited by leading experts Toyoki Kozai, Genhua Niu, and Joseph Masabni, this book aims to provide a platform of PFAL technology and science, including ideas on its extensive business and social applications towards the next-generation PFALs. The book is presented in four parts: Introduction, Basics, Applications, and Advanced Research. Part 1 covers why PFALs are necessary for urban areas, how they can contribute to the United Nations' Sustainable Development Goals, and a definition of PFAL in relation to the term "indoor vertical farm." Part 2 presents SI units and radiometric, photometric, and photonmetric quantities, types, components, and performance of LED luminaires, hydroponics and aquaponics, and plant responses to the growing environment in PFALs. Part 3 describes the indexes and definition of various productivity aspects of PFAL, provides comparisons of the productivity of the past and the present operation of any given PFALs, and compares PFALs with one another from the productivity standpoint by applying the common indexes. Part 4 describes the advances in lighting and their effects on plant growth, breeding of indoor and outdoor crops, production of fruiting vegetables and head vegetables, and concluding with a focus on a human-centered perspective of urban agriculture. Providing real-world insights and experience, Plant Factory Basics, Applications, and Advances is the ideal resource for those seeking to take the next step in understanding and applying PFAL concepts.

  • Hypercalcemia, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 50-4
    • Claudio Marcocci + 1 more
    • English

  • Electrochemical Biosensors

    Applications in Diagnostics, Therapeutics, Environment, and Food Management
    • 1st Edition
    • Pranveer Singh
    • English
    Electrochemical Nano-biosensors: Applications in Diagnostics, Therapeutics, Environment, and Food Management features a critical overview of different, recently reported nanomaterial-based electrochemical sensing and biosensing strategies. It is based on various analytical approaches for the point-of-care or POC healthcare related diagnostics, evaluation of contaminants, additives and adulterants in foods and environment management. Each section under the topic is discussed in its exhaustive detail, incorporating significant literature reviews spanning over two decades. The book critically analyzes issues and challenges for its applications in real world settings, universal applicability in resource limited sets-ups of remote areas, ease of integration with other sensing platforms, portability/miniatur... and more.

  • Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B

    • 1st Edition
    • Volume 185
    • English
    Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B, Volume 185 presents many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. This volume covers various topics, including tissue and protein fibrils imaging by AIE active molecules, theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment, and AIE active polymers and MOF materials for biological applications. Fluorescence-based monitoring and diagnosis platforms furnish extensive insights into the molecular mechanisms of cellular processes, helping us precisely guide therapeutics.

  • Regulatory Affairs in the Pharmaceutical Industry

    • 1st Edition
    • Javed Ali + 1 more
    • English
    Regulatory Affairs in the Pharmaceutical Industry is a comprehensive reference that compiles all the information available pertaining to regulatory procedures currently followed by the pharmaceutical industry. Designed to impart advanced knowledge and skills required to learn the various concepts of regulatory affairs, the content covers new drugs, generic drugs and their development, regulatory filings in different countries, different phases of clinical trials, and the submission of regulatory documents like IND (Investigational New Drug), NDA (New Drug Application) and ANDA (Abbreviated New Drug Application). Chapters cover documentation in the pharmaceutical industry, generic drug development, code of Federal Regulation (CFR), the ANDA regulatory approval process, the process and documentation for US registration of foreign drugs, the regulation of combination products and medical devices, the CTD and ECTD formats, and much more.

  • State of the Art on Grammatical Inference Using Evolutionary Method

    • 1st Edition
    • Hari Mohan Pandey
    • English
    State of the Art on Grammatical Inference Using Evolutionary Method presents an approach for grammatical inference (GI) using evolutionary algorithms. Grammatical inference deals with the standard learning procedure to acquire grammars based on evidence about the language. It has been extensively studied due to its high importance in various fields of engineering and science. The book's prime purpose is to enhance the current state-of-the-art of grammatical inference methods and present new evolutionary algorithms-based approaches for context free grammar induction. The book's focus lies in the development of robust genetic algorithms for context free grammar induction. The new algorithms discussed in this book incorporate Boolean-based operators during offspring generation within the execution of the genetic algorithm. Hence, the user has no limitation on utilizing the evolutionary methods for grammatical inference.

  • Current Research in Neuroadaptive Technology

    • 1st Edition
    • Stephen H. Fairclough + 1 more
    • English
    Current Research in Neuroadaptive Technology provides readers with insight into the state-of-the-art field of neuroadaptive technology. The book covers the breadth and depth of current research in this field, covering a range of application domains in sufficient technical detail. The multidisciplinary character of this field means that the publication of key research is often fragmented across specialist journals. Here, the editors have consolidated current research, carefully selecting key topics that are clustered around the concept of neuroadaptive technology. In summary, the book meets the needs of readers by consolidating multidisciplinary research around a nascent technological concept. The topic of neuroadaptive technology is novel and contemporary and editors Dr. Stephen H. Fairclough and Dr. Thorsten O. Zander have captured issues related to this emerging technology at the point of inception. It is a key reference for biomedical engineers and researchers in neural engineering, biomedical engineering, computer science, and mathematics.

  • Emerging Plant Growth Regulators in Agriculture

    Roles in Stress Tolerance
    • 1st Edition
    • M. Naeem + 1 more
    • English
    Emerging Plant Growth Regulators in Agriculture: Roles in Stress Tolerance presents current PGR discoveries and advances for agricultural applications, providing a comprehensive reference for those seeking to apply these tools for improved plant health and crop yield. As demand for agricultural crops and improved nutritional requirement continue to escalate in response to increasing population, plant researchers have focused on identifying scientific approaches to minimize the negative impacts of climate change on agriculture crops. Among the various applied approaches, the application of plant growth regulators (PGRs) have gained significant attention for their ability to enhance stress tolerance mechanisms. This book was developed to provide foundational and emerging information to advance the discovery of novel, cost-competitive, specific and effective PGRs for applications in agriculture.

  • Integrated Population Models

    Theory and Ecological Applications with R and JAGS
    • 1st Edition
    • Michael Schaub + 1 more
    • English
    Integrated Population Models: Theory and Ecological Applications with R and JAGS is the first book on integrated population models, which constitute a powerful framework for combining multiple data sets from the population and the individual levels to estimate demographic parameters, and population size and trends. These models identify drivers of population dynamics and forecast the composition and trajectory of a population. Written by two population ecologists with expertise on integrated population modeling, this book provides a comprehensive synthesis of the relevant theory of integrated population models with an extensive overview of　practical applications, using Bayesian methods by means of case studies. The book contains fully-documented, complete code for fitting all models in the free software, R and JAGS. It also includes all required code for pre- and post-model-fitting analysis. Integrated Population Models is an invaluable reference for researchers and practitioners involved in population analysis, and for graduate-level students in ecology, conservation biology, wildlife management, and related fields.　The text is ideal for self-study and advanced graduate-level courses.

  • Epigenetics in Precision Medicine

    • 1st Edition
    • Volume 30
    • Jose Luis Garcia-Gimenez
    • English
    In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic disorders, neurodegenerative diseases, bone disease, and immune-related disorders. The book examines the challenges of advancing epigenetics research and translating findings to the clinic and drug discovery in each of these areas, as well as current solutions; chapter authors discuss how to leverage epigenomic technologies, applications, and tools, such as next-generation sequencing, to discover new epigenetic biomarkers in disease and drug studies. Epigenetics in Precision Medicine focuses on complex epigenetic mechanisms in several pathologies, and explores how epigenetics can power the advance of precision medicine, not only by improving in vitro diagnostic and prognostic tools, but by providing new therapeutic approaches to treat human disease.

  • The DNA Replication-Repair Interface

    • 1st Edition
    • Volume 661
    • English
    Replication-Coupled Repair, Volume 661 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Repair of replication-born DNA breaks by sister chromatid recombination, High resolution and high throughput DNA cyclization measurements to interrogate DNA bendability, A programmable detection method for genomic signatures: from disease diagnosis to genome editing, Characterization of the telomerase modulating activities of yeast DNA helicases, Eukaryotic DNA replication with purified budding yeast proteins, Single molecule studies of yeast Rad51 paralogs, Light activation and deactivation of Cas9 for DNA repair studies, and more. Other chapters explore MIDAS: Direct sequencing to map mitotic DNA synthesis and common fragile sites at high precision, Studying the DNA damage response in embryonic systems, GLASS-ChIP to map Mre11 cleavage sites in the human genome, New chemical biology approaches to trap reaction intermediates in living cells, Single-molecule imaging approaches for monitoring replication fork conflicts at genomic DNA G4 structures and R-loops in human cells, Monitoring the replication of structured DNA through heritable epigenetic change, Visualizing replication fork encounters with DNA interstrand crosslinks, and much more.

  • Safety Risk Management for Medical Devices

    • 2nd Edition
    • Bijan Elahi
    • English
    Safety Risk Management for Medical Devices, Second Edition teaches the essential safety risk management methodologies for medical devices compliant with the requirements of ISO 14971:2019. Focusing exclusively on safety risk assessment practices required in the MedTech sector, the book outlines sensible, easily comprehensible, state-of the-art methodologies that are rooted in current industry best practices, addressing safety risk management of medical devices, thus making it useful for those in the MedTech sector who are responsible for safety risk management or need to understand risk management, including design engineers, product engineers, development engineers, software engineers, Quality assurance and regulatory affairs. Graduate-level engineering students with an interest in medical devices will also benefit from this book. The new edition has been fully updated to reflect the state-of-the-art in this fast changing field. It offers guidance on developing and commercializing medical devices in line with the most current international standards and regulations.

  • Current Progress in iPSC Disease Modeling

    • 1st Edition
    • Alexander Birbrair
    • English
    Current Progress in iPSC Disease Modeling, Volume Fourteen in the Advances in Stem Cell Biology series, is a timely and expansive collection of information and new discoveries in the field. This new volume addresses advances in research on how induced pluripotent stem cells are used for the creation of new tissues and organs. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions once impossible for some human diseases. This volume addresses iPSCs for vascular tissue engineering, bioprinting, derived lung organoids for pulmonary disorders, skeletal muscle engineering, human kidney organoids, and more. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field.

  • Foundations of Sleep Health

    • 1st Edition
    • F. Javier Nieto + 1 more
    • English
    Foundations of Sleep Health presents sleep health as a critical element of overall individual and population health. Sleep disorders are an increasing problem plaguing more than 40 million Americans. Sleep impacts numerous biological functions and plays a critical role in brain development, including learning and memory consolidation, cognitive functioning, and emotion regulation. This book provides an historic and current overview of the state of sleep health with an emphasis on the interplay between several levels of determinants and factors that influence sleep health. The text provides students in the health professions with in-depth discussion on the theory, research, and practice of sleep health, while also detailing mechanisms, hypotheses, and determinants of sleep and ways to improve sleep health.

  • iPSC Derived Progenitors

    • 1st Edition
    • Alexander Birbrair
    • English
    iPSC Derived Progenitors, Volume Thirteen in the Advances in Stem Cell Biology series is a timely collection of information and new discoveries in the field of stem cell biology. The book addresses the importance of induced pluripotent stems cells and how can they be differentiated into different progenitors. Progenitors cells are often the first-step to making more differentiating cell types. This volume addresses iPSCs derived from bone, dental pulp, craniofacial, neural stem cells, otic, cardiac, and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, organ transplantation, and is contributed by world-renowned authors.

  • AI, Edge and IoT-based Smart Agriculture

    • 1st Edition
    • Ajith Abraham + 4 more
    • English
    AI, Edge, and IoT Smart Agriculture integrates applications of IoT, edge computing, and data analytics for sustainable agricultural development and introduces Edge of Thing-based data analytics and IoT for predictability of crop, soil, and plant disease occurrence for improved sustainability and increased profitability. The book also addresses precision irrigation, precision horticulture, greenhouse IoT, livestock monitoring, IoT ecosystem for agriculture, mobile robot for precision agriculture, energy monitoring, storage management, and smart farming. The book provides an overarching focus on sustainable environment and sustainable economic development through smart and e-agriculture. Providing a medium for the exchange of expertise and inspiration, contributions from both smart agriculture and data mining researchers around the world provide foundational insights. The book provides practical application opportunities for the resolution of real-world problems, including contributions from the data mining, data analytics, Edge of Things, and cloud research communities working in the farming production sector. The book offers broad coverage of the concepts, themes, and instruments of this important and evolving area of IOT-based agriculture, Edge of Things and cloud-based farming, Greenhouse IOT, mobile agriculture, sustainable agriculture, and big data analytics in agriculture toward smart farming.

  • The Neurobiology, Physiology, and Psychology of Pain

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    The Neurobiology, Physiology and Psychology of Pain focuses on bettering readers’ understanding of acute and chronic pain. Featuring chapters on neurotransmitters, pharmacology, and brain imaging, this volume discusses, in detail, the mechanisms of pain and experimental studies undertaken to better understand the pathways involved. The translational work in this area has applicability for neurologists, anesthesiologists, pharmacologists, and anyone working in the intersection of these areas. This volume is integral for anyone interested in the molecular underpinnings of pain at every level.

  • COVID-19: Tackling Global Pandemics through Scientific and Social Tools

    • 1st Edition
    • S. Chatterjee
    • English
    Coronavirus disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2. It was first identified in December 2019 in Wuhan, Hubei, China, and has resulted in an ongoing pandemic. As of July 2020, more than 13.8　million cases have been reported across 188 countries and territories, resulting in more than 590,000 deaths. COVID 19: Tackling Global Pandemics through Scientific and Social Tools, is an amalgamation of scientific and social perspective. The book provides a selection of handpicked themes and topics relevant to COVID 19 pandemic across various disciplines delivered by experts in the domain. The Opinion section is a unique component of this book discussing important issues concerning the COVID 19. COVID 19: Tackling Global Pandemics through Scientific and Social Tools serves as single source of information ranging from clinical research to social science and even biotechnology to engineering in a single platform. But there is scarcity of a quality document that summarizes various aspects of a single event. Therefore, the purpose of this book is to provide scientific and social information on COVID 19 to all sectors of readers i.e. from students to researchers and even policy makers Divided into 13 chapters, the book begins with an in-depth introduction to the highly infectious disease COVID19. Followed by chapters on interventions, vaccine development, prevention and control COVID 19: Tackling Global Pandemics through Scientific and Social Tools also provides insights to current global situation, mathematical models and social factors like distancing and hand-washing. The book closes with a review on the use of artificial intelligence and engineered intervention. All are presented in a practical short format, making this volume a valuable resource for very broad academic audience.

  • Features and Assessments of Pain, Anesthesia, and Analgesia

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Features and Assessments of Pain, Anaesthesia and Analgesia examines the syndromes of pain and how they interlink with anesthesia and analgesics. The book covers assessments, screening and resources, and provides applications to related areas of medicine. It explores how the perception of pain results from a multifaceted interaction between illness beliefs, age, gender, time of onset, stress, socioeconomic status, and any number of other factors. In addition, the book scrutinizes how the neuroscience of pain in one condition may be relevant to understanding pain observed in other conditions.

  • Healthcare Strategies and Planning for Social Inclusion and Development

    Volume 1: Health for All - Challenges and Opportunities in Healthcare Management
    • 1st Edition
    • Basanta Kumara Behera + 2 more
    • English
    Healthcare Strategies and Planning for Social Inclusion and Development: Volume One: Health for All - Challenges and Opportunities in Healthcare Management examines health care management, particularly in developing countries, along with the key aspects of universal health required to address current global health issues. This new volume begins with an overview of the concept and definition of “Health for All.” The book covers how international organizations like the WHO support national health authorities in managing their core healthcare systems, support healthcare workforces, utilize technologies like health information systems, ensure health coverage and funding, and provide primary healthcare education. This volume is a useful resource to graduate students in public health and health care policy, public health professionals, health and social work researchers, and health policy makers interested in global health and primary healthcare services, particularly in developing countries.

  • Nanoparticle Therapeutics

    Production Technologies, Types of Nanoparticles, and Regulatory Aspects
    • 1st Edition
    • Prashant Kesharwani + 1 more
    • English
    Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.

  • Sturkie's Avian Physiology

    • 7th Edition
    • Colin G. Scanes + 1 more
    • English
    Sturkie's Avian Physiology, Seventh Edition is the classic comprehensive single volume on the physiology of domestic as well as wild birds. This latest edition is thoroughly revised and updated and features several new chapters with entirely new content on such topics as vision, sensory taste, pain reception, evolution, and domestication. Chapters throughout have been greatly expanded due to the many recent advances in the field. This book is written by international experts in different aspects of avian physiology. For easy reading and searches, this book is structured under a series of themes, beginning with genomic studies, sensory biology and nervous systems, and major organs. The chapters then move on to investigate metabolism, endocrine physiology, reproduction, and finally cross-cutting themes such as stress and rhythms. New chapters on feathers and skin are featured as well. Sturkie’s Avian Physiology, Seventh Edition is an important resource for ornithologists, poultry scientists, and other researchers in avian studies. It is also useful for students in avian or poultry physiology, as well as avian veterinarians.

  • Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A

    • 1st Edition
    • Volume 184
    • English
    Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A Volume 184, highlights many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. Emitting light is a fascinating photophysical phenomenon, its different forms have brought the attention of various disciplines of natural sciences for centuries. In the modern era of scientific generation, short-lived fluorescence light and its long-lived counterpart phosphorescence light has been employed for several chemo-sensing, bio-sensing, and bioimaging applications. The aggregation induced emission (AIE) phenomenon has appeared as a wand of modern science to convert aggregation-caused quenching (ACQ) materials into AIE active materials for a wide range of biomedical applications including biosensing, bioimaging and localization of molecules for better understanding of molecular mechanisms. This volume covers a wide range of topics which are not currently available in a single volume, including ACQ & AIE concept development; intracellular pH, temperature and viscosity sensing; imaging of cell membrane, lipid droplet, lysosome, and mitochondria; biosensing and Imaging of bacteria; nucleus and nucleic acid imaging.

  • Recent Trends in Computer-aided Diagnostic Systems for Skin Diseases

    Theory, Implementation, and Analysis
    • 1st Edition
    • Saptarshi Chatterjee + 2 more
    • English
    Recent Trends in Computer-aided Diagnostic Systems for Skin Diseases: Theory, Implementation, and Analysis provides comprehensive coverage on the development of computer-aided diagnostic (CAD) systems employing image processing and machine learning tools for improved, uniform evaluation and diagnosis (avoiding subjective judgment) of skin disorders. The methods and tools are described in a general way so that these tools can be applied not only for skin diseases but also for a wide range of analogous problems in the domain of biomedical systems. Moreover, quantification of clinically relevant information that can associate the findings of physicians/experts is the most challenging task of any CAD system. This book gives all the details in a step-by-step form for different modules so that the readers can develop each of the modules like preprocessing, feature extraction/learning, disease classification, as well as an entire expert diagnosis system themselves for their own applications.

  • Recombinant Protein Expression: Eukaryotic hosts

    • 1st Edition
    • Volume 660
    • English
    Recombinant Protein Expression, Part B, Volume 660 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on Multiplexed analysis protein: Protein interactions of polypeptides translated in Leishmania cell-free system, MultiBac system and its applications, performance and recent, Production of antibodies in Shuffle, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to enhance transcription in yeast, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to deregulate transcription in yeast, Antibody or protein-based vaccine production in plants, Cell-free protein synthesis, Plant-based expression of biologic drugs, and much more. Additional sections cover the Use of native mass spectrometry to guide detergent-based rescue of non-native oligomerization by recombinant proteins, Advancing overexpression and purification of recombinant proteins by pilot optimization through tandem affinity-buffer exchange chromatography online with native mass spectrometry, Method for High-Efficiency Fed-batch cultures of recombinant Escherichia coli, Method to transfer Chinese hamster ovary (CHO) shake flask experiments to the ambr® 250, and Expression of recombinant antibodies in Leishmania tarentolae.

  • Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II

    • 1st Edition
    • Volume 161
    • English
    Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II, Volume 161, in the International Review on Neurobiology serial highlights new advances, with this volume presenting chapters on topics including Introduction to Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Peri-adolescent Exposure to (Meth)amphetamine in Animal Models, The Impact of Adolescent Nicotine Exposure on Alcohol Use During Adulthood: The Role of Neuropeptides, Cannabis Exposure During Adolescence: A uniquely Sensitive Period for Neurobiological Effects, The Stoned Age: Sex Differences in the Effects of Adolescent Cannabinoid Exposure on Prefrontal Cortex Structure and Function in Animal Models, and more.

  • Side Effects of Drugs Annual

    A Worldwide Yearly Survey of New Data in Adverse Drug Reactions
    • 1st Edition
    • Volume 43
    • Sidhartha D. Ray
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 43, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered in this new release include Central Nervous System Stimulants and Drugs that Suppress Appetite, Antidepressants, Lithium, Drugs of Abuse, Hypnotics and Sedatives, Antipsychotic Drugs, Antiepileptics, Opioid Analgesics and Narcotic Antagonists, Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout, and much more.

  • Progress in Genomic Medicine

    From Research to Clinical Application
    • 1st Edition
    • Moyra Smith
    • English
    Progress in Genomic Medicine: From Research to Clinical Application provides a careful synthesis of the foundations, current trends and translational challenges in genomic medicine, clarifying pathways forward and enabling genomic medicine research and implementation across clinical settings and treatment development. Sections address the history and growth of genetic medicine, with a discussion of key studies in syndrome delineations, inherited diseases, biochemical genetics, and chromosome abnormalities, overview clinical applications made possible through genomic advances, with chapters on DNA sequencing for clinical genetic diagnosis, genotype-phenotype correlations in individuals and across populations, new-born screening for treatable genetic disorders, and more. In addition, social, ethical and public health aspects of applying genomic technologies are included throughout. Here, Dr. Smith applies her experience and participation in the field, across its major milestones, to put current research, clinical advances, and ongoing questions in context.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 117
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 117 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology.

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Perinatal and Reproductive Genetics
    • 7th Edition
    • Reed E. Pyeritz + 2 more
    • English
    **Selected for Doody’s Core Titles® 2024 in Clinical Genetics**Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Perinatal and Reproductive Genetics, Seventh Edition includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies in this growing field. The book is ideal for medical students, residents, physicians and researchers involved in the care of patients with genetic conditions. This comprehensive, yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly.Chapters from leading international researchers and clinicians focus on topics ranging from single gene testing to whole genome sequencing, whole exome sequencing, gene therapy, genome editing approaches, FDA regulations on genomic testing and therapeutics, and ethical aspects of employing genomic technologies.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 105
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 105, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on IgG N-glycans, Extracellular Vesicles: Potential Impact on Cardiovascular Diseases, Advances in Bone Turnover Markers, Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinases in Kidney Disease, and The Prothrombotic State in Cancer.

  • Introductory Microbiology Lab Skills and Techniques in Food Science

    • 1st Edition
    • Cangliang Shen + 1 more
    • English
    Introductory Microbiology Lab Skills and Techniques in Food Science covers topics on isolation, identification, numeration and observation of microorganisms, biochemistry tests, case studies, clinical lab tasks, and basic applied microbiology. The book is written technically with figures and photos showing details of every lab procedure. This is a resource that is skills-based focusing on lab technique training. It is introductory in nature, but encourages critical thinking based on real case studies of what happens in labs every day and includes self-evaluation learning questions after each lab section. This is an excellent guide for anyone who needs to understand how to apply microbiology to the lab in a practical setting.

  • Scientific Perspectives of Tea Plant Horticulture and Productivity

    • 1st Edition
    • L. Manivel
    • English
    Scientific Perspectives of Tea Plant Horticulture and Productivity is a complete, step-by-step guide on how to maximize tea plant growth, yield and quality. Chapters focus on the methods of cultivation, soil and water management, plant physiology, plant protection and weed control, problems from pollution and climate change, and eco-friendly remedial actions. This is an essential read for plant biologists and tea horticulturalists as the tea industry is struggling due to high production costs, changing climates and diminishing plant yields, with countries in Asia declaring the industry at ‘crisis point.’ Horticulturalists need solutions to problems with plant productivity, quality, stress management and eco-friendly cultivation practices. There have been several technological advances in the field and horticulturalists need guidance on how best to implement new technologies, hence the importance of this new resource.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 90
    • Jean-Francois Hamel
    • English
    The Oceanography of the Eastern English Channel: Past, Present and Future, Volume 90 in the Advances in Marine Biology series, is the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963. Readers will find updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release include Marine Environmental DNA: Approaches, Applications, and Opportunities, and The Biology and Ecology of the Banana Prawns.

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