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Experimental Models of Infection, Inflammation and Injury

  • 1st Edition, Volume 168 - March 31, 2022
  • Latest edition
  • Editor: David Montrose
  • Language: English

Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to effectively utilize experimental model systems.… Read more

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Description

Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to effectively utilize experimental model systems. Chapters in this new release include Induction and Evaluation of Murine T Cell Transfer Colitis, Modelling acute graft-versus-host disease (aGVHD) in murine bone marrow transplantation (BMT) models with MHC disparity, Mouse models of Graft-Versus-Host Disease, Preclinical Model of Multiple Sclerosis: Methods in Autoimmune Demyelination, Preclinical model of Multiple Sclerosis: focal, chemical or demyelination, Investigating demyelination, efficient remyelination and remyelination failure in organotypic cerebellar slice cultures: workflow and practical tips, and more.

Other notable sections cover Rheumatoid Arthritis: Methods for Two Murine Models, Induction of Pancreatitis in Mice with Susceptibility to Pancreatic Cancer, Small Animal Models of Thermal Injury, Large Animal Models of Thermal Injury, Small animal models of localized heart irradiation, Methods for Induction and Assessment of Intestinal Permeability in Rodent Models of Radiation Injury, and more.

Key features

  • Provides precise, step-by-step guidance on how to implement experimental systems
  • Presents a comprehensive background on the disease the model is being used to study
  • Offers insights into how the described disease models compare to other existing systems

Readership

Academic, researchers, government and industrial sectors

Table of contents

1. Induction and evaluation of murine colitis induced by T cell transfer
Suchandrima Saha, Ji Dong K Bai, David C. Montrose

2. Modeling acute graft-versus-host disease (aGVHD) in murine bone marrow transplantation (BMT) models with MHC disparity
Jasmin Scheurer, Frank Leithäuser, Klaus-Michael Debatin and Gudrun Strauss

3. Mouse models of graft-versus-host disease
Dilan A. Patel, Mark A. Schroeder, Jaebok Choi and John F. DiPersio

4. Preclinical model of multiple sclerosis: Methods in autoimmune demyelination
Jillian C. Nissen and Stella E. Tsirka

5. Preclinical model of multiple sclerosis: Focal, chemical or viral demyelination
Stella E. Tsirka and Jillian C. Nissen

6. Investigating demyelination, efficient remyelination and remyelination failure in organotypic cerebellar slice cultures: Workflow and practical tips
Rianne P. Gorter, Naomi S. Dijksman, Wia Baron and Holly Colognato

7. Rheumatoid arthritis: Methods for two murine models
Aisha M. Mergaert, Thomas F. Warner and Miriam A. Shelef

8. Induction of pancreatitis in mice with susceptibility to pancreatic cancer
Sarah B. Gitto, Sai Preethi Nakkina, Jordan M. Beardsley, Jignesh G. Parikh and Deborah A. Altomare

9. Small animal models of thermal injury
Roohi Vinaik, Ayesha Aijaz and Marc G. Jeschke

10. Large animal models of thermal injury
Ayesha Aijaz, Roohi Vinaik and Marc G. Jeschke

11. Small animal models of localized heart irradiation
Marjan Boerma, Vijayalakshmi Sridharan, Kimberly J. Krager and Snehalata A. Pawar

12. Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
Laura E. Ewing, Prabath G. Biju, Rupak Pathak, Stepan Melnyk, Martin Hauer-Jensen and Igor Koturbash

13. Methods and protocols for translatable rodent models of postsurgical pain
James W. Morgan, Sarah D. Pennypacker, E. Alfonso Romero-Sandoval and Miriam M. Fonseca

14. Methods and protocols for chemotherapy-induced peripheral neuropathy (CIPN) mouse models using paclitaxel
Sarah D. Pennypacker, Miriam M. Fonseca, James W. Morgan, Patrick M. Dougherty, Juan R. Cubillos-Ruiz, Roy E. Strowd and E. Alfonso Romero-Sandoval

15. The use of foodborne infection to evaluate bacterial pathogenesis and host response
Timothy H. Chu, Zhijuan Qiu and Brian S. Sheridan

16. Methods to evaluate virus-mediated acute lung inflammation
Hannah M. Ivester, Juselyn D. Tupik, Margaret A. Nagai-Singer, Sheryl L. Coutermarsh-Ott and Irving C. Allen

17. Induction and analysis of systemic C. albicans infections in mice
David Frank and Nick Carpino

Product details

  • Edition: 1
  • Latest edition
  • Volume: 168
  • Published: March 31, 2022
  • Language: English

About the editor

DM

David Montrose

Dr. Montrose received his B.A. in Biology from Manhattanville College and his Ph.D. in Biomedical Science from the University of Connecticut (Health Center campus). He received his post-doctoral training at Weill Cornell Medical College of Cornell University. He is currently an Assistant Professor and lab head in the Department of Pathology at Stony Brook University School of Medicine and a member of the Stony Brook Cancer Center. Dr. Montrose is also a member of the Molecular and Cellular Pharmacology (MCP) and Molecular Genetics and Microbiology (MGM) graduate programs.
Affiliations and expertise
Assistant Professor and Lab Head, Department of Pathology, Stony Brook University School of Medicine, NY, USA

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