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Immunoinformatics of Cancers

Practical Machine Learning Approaches Using R

  • 1st Edition - April 19, 2022
  • Latest edition
  • Authors: Nima Rezaei, Parnian Jabbari
  • Language: English

Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malign… Read more

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Description

Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.

This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies.

Key features

  • Presents the knowledge researchers need to apply computational techniques to immunodeficiencies
  • Provides the most practical material for bioinformatics approaches to the immunology of cancers
  • Gives straightforward and efficient explanations of programming and machine learning approaches in R
  • Includes details of the most useful databases, tools, programming packages and algorithms for immunoinformatics
  • Illuminates clear explanations with practical examples of immunoinformatic approaches to cancer

Readership

Researchers and graduate students in biological sciences; researchers and graduate students in computational and analytical sciences

Table of contents

Section I

1. Introduciton to cancer immunology

2. Introduction to bioinformatics

3. Practical databases in immunoinformatics

Section II

4. Principles of R programming

5. R programming in bioinformatics

6. Principle R packages in immunoinformatics

Section III

7. Introduction to machine learning

8. Naïve Bayes in R

9. Regressions in R

10. Linear and quadratic discriminant analysis

11. Support-vector Machine in R

12. Decision trees in R

13. Random forests in R

14. Neural Network in R

15. K Nearest Neighbour in R

16. Practice examples

Product details

  • Edition: 1
  • Latest edition
  • Published: April 19, 2022
  • Language: English

About the authors

NR

Nima Rezaei

Nima Rezaei, MD, PhD, is Professor of Clinical Immunology and Allergy at Tehran University of Medical Sciences, where he also serves as Associate Dean of International Affairs for the School of Medicine and Director of the Global Academic Program. He is Deputy President of the Research Center for Immunodeficiencies and holds an affiliated research appointment in the Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Sweden. He earned his MD from Tehran University of Medical Sciences and his PhD in Clinical Immunology and Human Genetics from the University of Sheffield, United Kingdom. His research addresses primary immunodeficiencies and translational immunology, with recent work extending into computational and AI-based approaches to immune profiling. He is the founder and President of the Universal Scientific Education and Research Network (USERN) and serves as co-editor of the Springer Nature series Advances in Experimental Medicine and Biology.

Affiliations and expertise
Professor of Clinical Immunology Karolinska Institutet, Stockholm, Sweden

PJ

Parnian Jabbari

Parnian Jabbari is a Medical Doctor at Tehran University of Medical Sciences, and a member of the Network of Immunity in Infection, Malignancy & Autoimmunity (NIIMA). She also works with the Universal Scientific Education & Research Network (USERN), based in Tehran, Iran.
Affiliations and expertise
Medical Doctor, Tehran University of Medical Sciences, Tehran, Iran

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