Advances in Microbial Physiology
- 1st Edition, Volume 80 - April 21, 2022
- Editors: Robert K. Poole, David J. Kelly
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 8 8 6 9 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 8 8 7 0 - 4
Advances in Microbial Physiology, Volume 150 in this important serial, highlights new advances in the field with this new volume including content by an international board of aut… Read more
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Microbiologists, biochemists, biotechnologists, and those interested in physiology, microbial biochemistry and its applications
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Nickel, an essential virulence determinant of Helicobacter pylori: Transport and trafficking pathways and their targeting by bismuth
- Abstract
- 1: Introduction
- 2: A handful of nickel-dependent enzymes
- 3: Nickel, a virulence determinant in H. pylori
- 4: The H. pylori urease
- 5: The [NiFe] hydrogenase and the crosstalk between the hydrogenase and urease maturation machineries
- 6: Nickel uptake in H. pylori
- 7: Mechanism of nickel efflux in H. pylori
- 8: H. pylori nickel chaperones and storage proteins
- 9: Acquisition during evolution of nickel related proteins by gastric Helicobacter species
- 10: Regulation of nickel transport and trafficking in H. pylori
- 11: The metal bismuth, a component of a treatment against H. pylori infection
- 12: Conclusions and perspectives
- Acknowledgments
- References
- Chapter Two: Neisseria gonorrhoeae physiology and pathogenesis
- Abstract
- 1: Introduction
- 2: Pathogenesis
- 3: Physiology
- 4: Conclusions and outlook
- References
- Chapter Three: Defenses of multidrug resistant pathogens against reactive nitrogen species produced in infected hosts
- Abstract
- 1: Introduction
- 2: Pathogens are exposed to reactive nitrogen species in infected hosts
- 3: Bacterial targets of RNS and responses
- 4: Defenses of major human pathogens against RNS
- 5: Effect of nitrosative stress analyzed by whole genome and proteomic approaches
- 6: Conclusions and future perspectives
- Acknowledgments
- References
- Chapter Four: Metabolic potential of anaerobic methane oxidizing archaea for a broad spectrum of electron acceptors
- Abstract
- 1: Introduction
- 2: Metabolic flexibility of anaerobic methanotrophic archaea
- 3: Possible mechanisms of electron acceptor reduction
- 4: Environmental implications and potential application
- 5: Knowledge gaps and future work
- Acknowledgments
- References
- Chapter Five: How Streptomyces thrive: Advancing our understanding of classical development and uncovering new behaviors
- Abstract
- 1: Introduction
- 2: Classical Streptomyces development
- 3: Alternative developmental strategies and behaviors
- 4: Volatile emissions: Environmental and behavioral impacts
- 5: Phage defense strategies of Streptomyces
- 6: Conclusions
- References
- No. of pages: 246
- Language: English
- Edition: 1
- Volume: 80
- Published: April 21, 2022
- Imprint: Academic Press
- Hardback ISBN: 9780323988698
- eBook ISBN: 9780323988704
RP
Robert K. Poole
Professor Robert K Poole is Emeritus Professor of Microbiology at the University of Sheffield, UK. He was previously West Riding Professor of Microbiology at Sheffield and until 1996 held a Personal Chair in Microbiology at King’s College London. During his long career, he has been awarded several research Fellowships, and taken sabbatical leave at the Australian National University, Kyoto University and Cornell University. His career-long interests have been in the areas of bacterial respiratory metabolism, metal-microbe interactions and bioactive small gas molecules. In particular, he has made notable contributions to bacterial terminal oxidases and resistance to nitric oxide with implications for bacterial pathogenesis. He co-discovered the flavohaemoglobin Hmp, now recognised as the preeminent mechanism of nitric oxide resistance in bacteria. He has served as Chairman of numerous research council grant committees, held research grants for over 40 years and published extensively (h-index, 2024 = 70). He served on several Institute review panels in the UK and overseas. He is a Fellow of the Royal Society of Chemistry and the Royal Society of Biology.
DK
David J. Kelly
Professor David Kelly is Emeritus Professor of Microbial Physiology at the University of Sheffield, UK. He has >35 years research expertise in bacterial physiology and biochemistry, membrane protein transport processes and bioenergetics, and has worked with the zoonotic food-borne pathogen Campylobacter jejuni for >25 years. A major program to study C. jejuni physiology was carried out in his laboratory, in particular the responses to oxygen, many aspects of carbon metabolism and functional analysis of the electron transport chains. He has long-standing interests in membrane transport mechanisms and in the 1990s discovered an entirely new class of periplasmic binding-protein dependent prokaryotic solute transporters, the TRAP transporters, now known to be common in a diverse range of bacteria and archaea. He has published >150 papers (h-index 2024 = 56), held numerous grants, served on grant committees and has been a regular invited speaker at national and international conferences. He is the recipient of a Leverhulme Emeritus Fellowship from the Leverhulme Trust, UK.