Advances in Microbial Physiology

1st Edition, Volume 80 - April 21, 2022
Imprint: Academic Press
Editors: Robert K. Poole, David J. Kelly
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 8 6 9 - 8
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 8 7 0 - 4

Advances in Microbial Physiology, Volume 150 in this important serial, highlights new advances in the field with this new volume including content by an international board of aut… Read more

Purchase options

World Book Day Celebration!

Save up to 30% on books and eBooks!

Shop now

Institutional subscription on ScienceDirect

Request a sales quote

Advances in Microbial Physiology, Volume 150 in this important serial, highlights new advances in the field with this new volume including content by an international board of authors. Chapters in this new release include Organization of respiratory chains in the bacterial cell, Anaerobic methane oxidizing archaea, Dawn of the DedA: the structure and function of the DedA family of integral membrane proteins associated with bacterial viability and antimicrobial resistance, Nickel, an essential virulence determinant of Helicobacter pylori: trafficking pathways and their targeting by bismuth, Dissimilatory sulfur compounds oxidation in thermophilic and chemolithoautotrophic bacteria belonging to the Aquificales order, and much more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Chapter One: Nickel, an essential virulence determinant of Helicobacter pylori: Transport and trafficking pathways and their targeting by bismuth
Abstract
1: Introduction
2: A handful of nickel-dependent enzymes
3: Nickel, a virulence determinant in H. pylori
4: The H. pylori urease
5: The [NiFe] hydrogenase and the crosstalk between the hydrogenase and urease maturation machineries
6: Nickel uptake in H. pylori
7: Mechanism of nickel efflux in H. pylori
8: H. pylori nickel chaperones and storage proteins
9: Acquisition during evolution of nickel related proteins by gastric Helicobacter species
10: Regulation of nickel transport and trafficking in H. pylori
11: The metal bismuth, a component of a treatment against H. pylori infection
12: Conclusions and perspectives
Acknowledgments
References
Chapter Two: Neisseria gonorrhoeae physiology and pathogenesis
Abstract
1: Introduction
2: Pathogenesis
3: Physiology
4: Conclusions and outlook
References
Chapter Three: Defenses of multidrug resistant pathogens against reactive nitrogen species produced in infected hosts
Abstract
1: Introduction
2: Pathogens are exposed to reactive nitrogen species in infected hosts
3: Bacterial targets of RNS and responses
4: Defenses of major human pathogens against RNS
5: Effect of nitrosative stress analyzed by whole genome and proteomic approaches
6: Conclusions and future perspectives
Acknowledgments
References
Chapter Four: Metabolic potential of anaerobic methane oxidizing archaea for a broad spectrum of electron acceptors
Abstract
1: Introduction
2: Metabolic flexibility of anaerobic methanotrophic archaea
3: Possible mechanisms of electron acceptor reduction
4: Environmental implications and potential application
5: Knowledge gaps and future work
Acknowledgments
References
Chapter Five: How Streptomyces thrive: Advancing our understanding of classical development and uncovering new behaviors
Abstract
1: Introduction
2: Classical Streptomyces development
3: Alternative developmental strategies and behaviors
4: Volatile emissions: Environmental and behavioral impacts
5: Phage defense strategies of Streptomyces
6: Conclusions
References

Robert K. Poole

Professor Robert K Poole is Emeritus Professor of Microbiology at the University of Sheffield, UK. He was previously West Riding Professor of Microbiology at Sheffield and until 1996 held a Personal Chair in Microbiology at King’s College London. During his long career, he has been awarded several research Fellowships, and taken sabbatical leave at the Australian National University, Kyoto University and Cornell University. His career-long interests have been in the areas of bacterial respiratory metabolism, metal-microbe interactions and bioactive small gas molecules. In particular, he has made notable contributions to bacterial terminal oxidases and resistance to nitric oxide with implications for bacterial pathogenesis. He co-discovered the flavohaemoglobin Hmp, now recognised as the preeminent mechanism of nitric oxide resistance in bacteria. He has served as Chairman of numerous research council grant committees, held research grants for over 40 years and published extensively (h-index, 2024 = 70). He served on several Institute review panels in the UK and overseas. He is a Fellow of the Royal Society of Chemistry and the Royal Society of Biology.

Affiliations and expertise

West Riding Professor of Microbiology, Department of Molecular Biology and Biotechnology, University of Sheffield, UK

David J. Kelly

Professor David Kelly is Emeritus Professor of Microbial Physiology at the University of Sheffield, UK. He has >35 years research expertise in bacterial physiology and biochemistry, membrane protein transport processes and bioenergetics, and has worked with the zoonotic food-borne pathogen Campylobacter jejuni for >25 years. A major program to study C. jejuni physiology was carried out in his laboratory, in particular the responses to oxygen, many aspects of carbon metabolism and functional analysis of the electron transport chains. He has long-standing interests in membrane transport mechanisms and in the 1990s discovered an entirely new class of periplasmic binding-protein dependent prokaryotic solute transporters, the TRAP transporters, now known to be common in a diverse range of bacteria and archaea. He has published >150 papers (h-index 2024 = 56), held numerous grants, served on grant committees and has been a regular invited speaker at national and international conferences. He is the recipient of a Leverhulme Emeritus Fellowship from the Leverhulme Trust, UK.

Affiliations and expertise

Professor of Microbiology, Department of Molecular Biology and Biotechnology, University of Sheffield, UK

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health