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Elsevier

Books in Life sciences

  • Big Data Analytics in Agriculture

    Algorithms and Applications
    • 1st Edition
    • Manish K. Pandey + 3 more
    • English
    Big Data Analytics in Agriculture focuses on the quantitative and qualitative assessment of agricultural systems using state‑of‑the‑art technologies to deliver practical improvements in agricultural production.Addressin... the challenge of translating data into real‑world applications, the book provides a comprehensive mapping of the entire data lifecycle—from data generation, storage, and curation to processing and implementation. It guides readers through the steps required to produce high‑quality, reliable information that supports effective decision‑making. Following a logical progression, the volume demonstrates how diverse data streams converge into decision‑support systems and how they can be transformed into actionable outcomes, aligned with intelligent, efficient, technologically advanced, economically viable, and politically and culturally sustainable practices.This book further explores the integration of information and communication technologies (ICT) and the Internet of Things (IoT) for managing rural assets and enhancing economic and environmental performance in spatially and temporally variable agricultural environments. Topics covered include big data analytics, data management and processing, and a range of algorithms and applications relevant to agriculture. Subtopics encompass artificial intelligence‑ and machine‑learning‑ena... smart and precision irrigation, disease and pest management, microclimatic forecasting, preventive fertigation and chemigation, data‑driven smart farming through the Internet of Everything (IoE), and supply‑chain analytics for improved farm‑level operations.

  • Innovation in Emergency Medicine

    Technology Development and Commercialization Handbook
    • 1st Edition
    • Nancy Patterson + 3 more
    • English
    Innovation in Emergency Medicine: Technology Development and Commercialization Handbook is a step-by-step guide to emergency medicine technology innovation reflecting recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads engineers, clinicians, students, researchers, and entrepreneurs through a clear process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. This new volume in the Clinical and Medical Innovation Series will be of interest to every biomedical engineer and those working in emergency medicine who has ever had a good idea for an invention but does not know where and how to start bringing it to the bedside.

  • Electrocardiography of Laboratory Animals

    • 3rd Edition
    • Meg M. Sleeper + 1 more
    • English
    Electrocardiography of Laboratory Animals, Third Edition, provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book begins with the fundamental principles of electrocardiography and its applications in drug safety evaluation but then covers electrocardiography in a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees.Addition... it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. It is an essential resource for biological and medical researchers, veterinarians, zoologists, and students.

  • Olive 4.0

    Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production
    • 1st Edition
    • Najla Trabelsi + 1 more
    • English
    Olive 4.0: Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production explores the revolutionary impact of Industry 4.0 technologies on the traditional olive sector. As olive farming and oil production face increasing pressures from labor shortages, resource constraints, and environmental concerns, this book addresses the urgent need for digital innovation tailored specifically to this industry. By focusing on cutting-edge tools such as the Internet of Things (IoT), Artificial Intelligence (AI), robotics, blockchain, and smart sensors, it highlights how these advances can enhance sustainability, productivity, and quality throughout the entire olive supply chain—from grove management to oil processing and distribution.Whether for smallholders seeking affordable solutions or large producers aiming for automation and traceability, the book delivers science-backed insights that promote eco-friendly practices while improving efficiency and reducing waste. Importantly, it also addresses challenges related to technology accessibility and equitable adoption, ensuring that innovations benefit a broad spectrum of stakeholders and support long-term sustainability goals.

  • Introduction to Bioinformatics and Machine Learning

    • 1st Edition
    • Milana Frenkel-Morgenstern
    • English
    Introduction to Bioinformatics and Machine Learning provides comprehensive instruction in modern computational biology by integrating bioinformatics, genomics, artificial intelligence, and machine learning into a unified learning framework. The book bridges the gap between biological data analysis and computational methods, covering fundamental concepts in molecular biology and bioinformatics together with practical applications of machine learning to genomics, transcriptomics, proteomics, microbiome research, structural biology, NGS technologies, liquid biopsy, cancer genomics, and precision medicine. Readers are introduced to DNA and RNA sequencing technologies, genome assembly, sequence alignment, variant discovery, gene expression analysis, fusion gene detection, protein structure prediction, biological databases, statistical analysis, explainable artificial intelligence, and predictive modeling. Throughout the book, real-world biomedical case studies demonstrate how computational methods are transforming modern biological and clinical research; and both bioinformatics and machine learning are addressed in a coherent and accessible manner, emphasizing practical problem-solving, reproducible computational workflows, and biological interpretation of results.Designed for upper-level undergraduate students, graduate students, and researchers, this book serves as both a classroom textbook and practical assignments for those working at the interface of biology, computer science, medicine, and data science.

  • Endophyte Technology

    An Integrative Approach for Agriculture, Healthcare, and Environmental Sustainability
    • 1st Edition
    • Zahoor Ahmed Wani + 2 more
    • English
    Endophyte Technology: An Integrative Approach for Agriculture, Healthcare, and Environmental Sustainability explores how understanding endophyte biology can be utilized in agriculture, medicine, and environmental remediation. As the global population continues to grow, the pressures on agricultural systems to produce sufficient food sustainably are intensifying. Concurrently the need for innovative medical solutions and effective environmental conservation practices is becoming increasingly urgent. This book addresses these critical needs by offering a detailed account of endophytes and their potential applications across these important fields.The book is structured into three parts, covering agricultural, ecological, and pharmaceutical aspects of endophytes. Part I looks into the role of endophytes in agriculture, discussing their potential in promoting plant growth, enhancing nutrient acquisition, and providing stress tolerance to plants. It explores how endophytes can promote sustainable agriculture, reducing the reliance on synthetic fertilizers and pesticides. Subsequent chapters explore topics such as endophyte colonization patterns, phytohormone production, and the development of bioformulations like biofertilizers, biopesticides, and biocontrol agents. Part II focuses on the ecological significance of endophytes, examining their role in ecosystem functioning, bioremediation, and adaptation to extreme environments. Part III highlights the pharmaceutical potential of endophytes, centering their ability to produce bioactive metabolites with antimicrobial, anticancer, and anti-inflammatory properties, and their role in drug discovery and biofuel production.This book is an important resource for undergraduate and postgraduate students as well as researchers and professionals in agriculture, horticulture, botany, biochemistry, and biotechnology.

  • Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies

    • 1st Edition
    • Gentle Sunder Shrestha + 3 more
    • English
    Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies is a practical resource aimed at clinicians working in the field of neurology. By providing an algorithmic approach to diagnosing patients, this volume helps clinicians quickly and systematically approach patients, minimizing the risk of missing common neurological emergencies. Offering case studies and various common neurological scenarios, readers will be able to pick up on warning signs of serious neurological emergencies and treat patients effectively. Users will find this to be a valuable guide to help manage patients with neurological emergencies with limited resources.

  • Federated Intelligence in Medicine

    AI-Driven Robotics for Secure and Intelligent Healthcare Systems
    • 1st Edition
    • Manisha Guduri + 3 more
    • English
    Federated Intelligence in Medicine: AI-Driven Robotics for Secure and Intelligent Healthcare Systems explores the rapidly evolving field where medical robotics intersects with cutting-edge artificial intelligence and secure data-sharing technologies. Covering a comprehensive range of topics, the book begins with foundational knowledge in medical robotics and Generative AI, progressing to advanced concepts such as federated learning and architectural modeling tailored for AI-driven robotic systems. Readers will explore algorithms enhancing surgical robotics, remote robotic surgeries, and human-robot interaction. The text also tackles AI-driven diagnostic robots, privacy preservation through homomorphic encryption, and differential privacy and emerging medical imaging techniques integrated with robotics.Later chapters examine the synergy of large language models, agent AI, and edge AI with robotic technologies, providing both theoretical frameworks and practical case studies that illuminate real-world applications and challenges. This book is an invaluable resource for researchers and academicians engaged in artificial intelligence, robotics, and medical technology. It also serves undergraduate and graduate students in Biomedical Engineering, Electronics and Electrical Engineering, and Computer Science and Engineering.

  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1st Edition
    • Ashutosh Pareek + 4 more
    • English
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.

  • Applications of Microfluidics Device Technology

    • 1st Edition
    • Volume 227
    • English
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

  • PFAS Contamination

    Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies
    • 1st Edition
    • Saranya Narayanasamy + 1 more
    • English
    PFAS Contamination: Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies offers a comprehensive overview of per- and polyfluoroalkyl substances (PFAS), highlighting their global environmental prevalence, toxicological effects and health risks, and state-of-the-art remediation approaches. The book taps into the increasing recognition of PFAS as “forever chemicals” and explores the widespread contamination of these compounds in water, soil, and air along with their toxicological effects on human health and the ecosystem. It highlights advancements in detection methods as well as physicochemical, biological, and emerging remediation technologies, including plasma-based technologies, bioremediation, and advanced nanotechnology-based methods, such as plasma technology, bioremediation, and adsorption methods.Case studies illustrate successful applications, and the book examines policy frameworks, regulatory measures, and the public health impact of PFAS. This resource serves as a vital source of information for environmental toxicologists, environmental scientists, environmental consultants, engineers, and regulators studying PFAS prevalence, toxicity mechanisms, remediation, and practical strategies for mitigating PFAS contamination and fostering a deeper understanding of the global efforts to address this critical issue.

  • LGBTQ+ Access to Inflammatory Bowel Disease Healthcare

    Current Trends and Considerations
    • 1st Edition
    • Lesley Dibley + 1 more
    • English
    LGBTQIA+ Access to Inflammatory Bowel Disease Healthcare: Current Trends and Considerations illuminates the unique medical, surgical, and mental health issues faced by LGBTQIA+ patients, providing clinicians with the knowledge to understand why these issues arise and how they can be effectively addressed. This crucial resource aims to elevate awareness among healthcare providers and commissioners about the need for gender- and identity-affirming care. As societal recognition of LGBTQIA+ rights grows, this book steps into the unexplored terrain of LGBTQIA+ healthcare and IBD, addressing both medical complexities and the social and political dimensions of care. The book opens with an introduction to the significance of LGBTQIA+ access to healthcare and the necessity for clinician awareness. It includes contributions from leading experts and a comprehensive glossary of relevant LGBTQIA+ terms. Key topics covered are the socio-cultural and political history influencing healthcare access, the impact of stigma on healthcare utilization and adherence, and specific medical, surgical, and mental health considerations for transgender patients with IBD. The text also covers gender- and identity-affirming practices, advocating for effective patient-provider communication and supportive healthcare environments, even in challenging settings. The concluding chapters assess the progress made and the journey ahead in LGBTQIA+ IBD care. Designed for clinicians and healthcare providers, this book serves as an indispensable reference, consolidating essential contemporary evidence into a single, accessible resource. Whether you are a gastroenterologist, surgeon, mental health professional, or healthcare researcher, this book offers the insights and tools necessary to deliver inclusive and effective care, keeping pace with the evolving healthcare advocacy and equality landscape.

  • Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science

    • 1st Edition
    • Rahul Mehra + 4 more
    • English
    Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science is a critical resource for researchers, industry professionals, and academics seeking to stay at the forefront of the evolving food landscape. This comprehensive volume is organized into six sections, beginning with foundational principles in food, nutrition, and culinary science—covering chapters such as Interconnection Between Food, Nutrition, and Culinary Science and Fundamentals of Food Science and Technology. It then progresses by exploring cutting-edge innovations in culinary science, including Molecular Gastronomy and Neuro-Gastronomy, alongside practical insights into food processing advancements like AI and Robotics. The book dedicates significant focus to nutrition and health, highlighting breakthroughs in personalized nutrition, nutrigenomics, and functional foods. The final sections address sustainability, ethical practices, and future horizons, including discussions on food waste reduction, sustainable food systems, and future foods. Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science is vital for leveraging scientific and technological progress to develop healthier, safer and more sustainable food solutions. By integrating insights from culinary arts, food processing, and nutritional science, it equips professionals with the knowledge to innovate responsibly and address global issues such as food security, safety, and environmental impact. Whether exploring the role of emerging ingredients or the future of personalized diets, this book offers a detailed roadmap to shape the future of food in both academia and industry.

  • The Fundamentals of Customer-Centered Design of Food Products

    A Multisensory Strategy Integrating Emerging Techniques
    • 1st Edition
    • Luis H. Reyes + 3 more
    • English
    The Fundamentals of Customer-Centered Design of Food Products: A Multisensory Strategy for Integrating Emerging Techniques, is a comprehensive guide for students, and food industry professionals, dedicated to creating food and beverage products that truly resonate with today's consumers. This fundamental resource bridges the gap between traditional product-centric development and modern, holistic approaches that focus on the complete sensory and consumer experience. Divided into three sections, the book begins with laying the foundations for understanding customer-centered food product design and understanding the consumer in multisensory food experiences. Section two explores how each sensory modality interacts to influence consumer perception and satisfaction to create products with optimized nutrition and personalized consumer appeal. The book concludes with section three highlighting the technology and innovative tools such as smart sensors, digital tools, and sustainable processes, used to achieve consumer-centered food product design. The authors also discuss how to communicate sensory value in marketing and brand strategies and future perspectives in consumer-centered multi-sensory food design.

  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • Hypoxia-induced Tumor Heterogeneity and Immune Evasion

    Clinical Interventions
    • 1st Edition
    • Benjamin Bonavida + 1 more
    • English
    Hypoxia-induced Tumor Heterogeneity and Immune Evasion: Clinical Interventions explores how hypoxic stress within the tumor microenvironment drives cancer progression, immune escape, and resistance to therapy. This volume integrates foundational and cutting-edge insights into tumor biology, immunology, and therapeutic innovation. The book is structured into five parts, covering tumor heterogeneity, hypoxia-driven mechanisms, immune evasion, clinical diagnostics, and future directions. It brings together global experts to examine how hypoxia shapes tumor evolution, alters immune responses, and influences treatment outcomes. Topics include metabolic reprogramming, angiogenesis, immune suppression, and hypoxia-targeted therapies, with emphasis on translational relevance. This resource benefits researchers, clinicians, and advanced students by offering a comprehensive, up-to-date synthesis of a rapidly evolving field. It supports deeper understanding of tumor complexity and equips readers with knowledge to inform experimental design, clinical strategies, and therapeutic development in oncology.

  • Complications in Spinal Surgery

    A Comprehensive Guide
    • 1st Edition
    • Rafael De la Garza Ramos + 2 more
    • English
    Complications in Spinal Surgery: A Comprehensive Guide is a comprehensive reference for before and after surgery, covering common complications and rare complexities. The book is divided into major sections, including safety in spine surgery, general complications, complications by region (cervical, thoracic, lumbar, and sacral), complications related to pediatrics, and predictive analytics. Although some complications can happen irrespective of the spinal region, dividing into anatomical sections make the most sense for the reader. Designed to benefit both surgeons-in-training... and fellows—and seasoned professionals in orthopedic and neurosurgical spine practice, this book provides critical insights into the prevention, recognition, and management of complications.Unique to this book are the other implications of complications, such as how to approach patients and families, the medicolegal aspects of complications, and how to deal with these situations at a personal level. With its evidence-based approach, real-world case discussions, and expert perspectives, it equips readers with the knowledge and confidence to navigate the complexities of spine surgery and improve patient outcomes.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1st Edition
    • Luca Saba + 1 more
    • English
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

  • Nanofibers in Cancer Management

    Therapeutic Delivery Perspectives
    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Nanofibers in Cancer Management: Therapeutic Delivery Perspectives provides an authoritative academic resource on the role of nanofibers in advancing cancer therapy. It consolidates fundamental principles and translational strategies to address limitations of conventional treatments. The book explores polymer chemistry, fabrication techniques, and smart nanofiber systems tailored for major cancers, including breast, lung, liver, colorectal, prostate, pancreatic, ovarian, melanoma, oral, and CNS tumors. It emphasizes drug encapsulation, sustained release, localized delivery, and regulatory considerations, supported by evidence-based insights and global expertise. Readers benefit from a structured, modular approach that bridges material science and clinical application. This resource equips researchers, clinicians, and graduate students with practical knowledge to innovate targeted therapies and overcome challenges such as multidrug resistance and systemic toxicity.

  • Spider Systematics and Taxonomy

    • 1st Edition
    • Dimitar Dimitrov + 1 more
    • English
    In the last decade or so, a large number of new spider species have been discovered and described, and many genera and families have been revised. Yet, a single comprehensive resource has been lacking to update spider taxonomy. Spider Systematics and Taxonomy aims to present these major developments in the field, as well as to show how technological advancements have driven these changes. Spider groups covered in most detail are those which have recently seen the most significant discoveries and changes. Later chapters highlight the impact of recent technological developments on our knowledge of spider taxonomy, with topics including phylogenomics, artificial intelligence, and novel imaging technologies. Finally, an outlook on future priorities for spider taxonomy research as well as expected developments will be explored.Spider Systematics and Taxonomy is a valuable reference with illustrations and vivid photographs included throughout to showcase spider diversity and relationships. This will serve as a key resource for arachnology researchers, graduate and postgraduate students wishing to come up to date on the latest advances in the field. Researchers in adjacent fields and those working in taxonomy generally will also benefit from this work.

  • Management of Chronic Kidney Disease and Its Complications

    • 1st Edition
    • Thakur Gurjeet Singh + 4 more
    • English
    Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

  • Prokineticins

    From the Gastrointestinal Tract to Neuroinflammation
    • 1st Edition
    • Roberta Lattanzi + 1 more
    • English
    Prokineticins: From the Gastrointestinal Tract to Neuroinflammation explores the intricate biology and pathophysiological roles of prokineticin peptides, from developmental processes in the heart and brain to the regulation of homeostasis in health and disease. Beginning with an introduction to prokineticins, the book moves on to discuss physiological functions across the human body, including the regulation of circadian rhythm, food intake, heart and kidney function and the reproductive system. Chapters then cover the prokineticin system in neurogenesis dysfunction, obesity and diabetes, reproductive system disorders and cardiovascular diseases.The prokinetcin system is also explored in the context of neurodegenerative disease and traumatic brain injury, pain, inflammation, infection and cancer. It also investigates natural and pharmacological inhibitors of PK receptors and closes with a look towards future research perspectives.

  • Pheochromocytoma, Paraganglioma and Adrenocortical Carcinoma: Physiopathology and Diagnosis

    • 1st Edition
    • Volume 133
    • English
    Volume 133 provides a comprehensive and up-to-date overview of three of the most challenging endocrine neoplasms—pheochromo... paraganglioma, and adrenocortical carcinoma. Bringing together contributions from internationally recognized experts, this volume explores the latest advances in tumor biology, genetics, molecular mechanisms, and endocrine pathophysiology, while offering a practical approach to modern diagnostic strategies. Readers will find detailed discussions on hereditary syndromes, genotype–phenotype correlations, biochemical testing, imaging modalities, histopathological assessment, molecular profiling, and emerging biomarkers that are reshaping the diagnosis and risk stratification of adrenal tumors. Integrating cutting-edge scientific discoveries with clinical practice, this volume serves as an essential resource for endocrinologists, oncologists, endocrine surgeons, pathologists, radiologists, nuclear medicine specialists, geneticists, researchers, and trainees seeking to improve the diagnosis and understanding of these rare but clinically significant endocrine malignancies. With its multidisciplinary perspective and strong translational focus, Volume 133 is an indispensable reference for clinicians and scientists dedicated to advancing adrenal tumor care and research.

  • Protein Misfolding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Misfolding explores the structural and biochemical foundations of protein misfolding, highlighting its wide-reaching implications for cellular function, disease progression, and biomedical innovation. This book provides a comprehensive understanding of how proteins deviate from their native conformations and the resulting biological consequences. Focusing on both physiological and pathological misfolding, the volume covers essential topics such as folding quality control, molecular chaperones, degradation pathways, and proteostasis. It presents in-depth analyses of protein aggregation mechanisms, amyloid formation, and misfolding-associate... diseases including Alzheimer's, Parkinson's, and prion-related disorders. Additional chapters explore structural approaches to understanding misfolded states, computational modeling of aggregation kinetics, and current efforts to design therapeutics that restore folding homeostasis or prevent toxic accumulation. The book also addresses the cellular response to misfolding stress and the integration of folding dynamics with cellular signaling pathways.This book is a valuable resource for researchers, educators, and professionals in biochemistry, structural biology, molecular medicine, biotechnology, and related disciplines. It supports efforts to understand the fundamental principles of protein structure and function, while offering insight into emerging therapeutic strategies and future research directions in disease-focused protein science.

  • Mycorrhizal Symbiosis

    • 1st Edition
    • Volume 121
    • English
    Mycorrhizal Symbiosis, Volume 120 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Molecular regulation and host-control of Arbuscular Mycorrhizal Symbiosis, Plant-AM fungus communication: key role of nutrition in cry for help signals, Nutrient exchange in mycorrhizal symbiosis, Biotechnological solutions based on mycorrhizae for the improvement of plants against abiotic stress, Mycorrhizae and plant responses to salinity, Mycorrhizal symbiosis regulating plant-biotic interactions, Nutritional quality of mycorrhizal crops: current and future challenges from a One Health perspective, The Role of Arbuscular Mycorrhizal Fungi in Fruit Trees and the Challenges of Their Application, and much more.Additional sections cover Mycorrhizal fungi: key to the functionality and conservation of native forests in southern Chile and Applications of mycorrhizae in ecological restoration.

  • Digital Twins and Predictive Modeling in Robotic Surgery

    • 1st Edition
    • Mudassir Khan + 3 more
    • English
    Digital Twins and Predictive Modeling in Robotic Surgery addresses the transformative convergence of digital twin technology, predictive analytics, and robotic surgery. This reference responds to the critical need for a comprehensive resource that bridges simulation science, artificial intelligence, and real-time robotic execution, facilitating enhanced surgical precision, patient-specific planning, and intraoperative decision-making. The content is organized into four parts covering foundational intelligent surgical systems, predictive modeling and simulation, clinical applications with case studies, and challenges alongside future directions. Topics include AI integration, IoT-enabled sensor networks, digital twin architectures encompassing the entire surgical ecosystem, surgical workflow modeling, risk assessment, human-robot interaction, technology acceptance, ethical and regulatory considerations. Real-world examples from smart hospitals worldwide illustrate practical implementation. This books benefits biomedical engineers, researchers, and healthcare system architects by providing interdisciplinary insights, practical implementation frameworks, and cutting-edge case studies. It supports improved surgical planning, precision, and decision-making, empowering end users to advance the adoption of intelligent, AI-powered robotic surgery systems in clinical practice and research environments.

  • Pharmaceutical QbD with Design of Experiments

    Statistical Tools and Applications in Drug Delivery Systems
    • 1st Edition
    • Khushwant Yadav
    • English
    Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

  • Ethnoveterinary Practices in Animal Agriculture

    • 1st Edition
    • Munesh Kumar + 3 more
    • English
    Ethnoveterinary medicine is aimed at maintaining animal health by drawing from cultural values, traditional knowledge, surgical techniques, metaphysical principles, and local resources. Ethnoveterinary Practices in Animal Agriculture explores how traditional ethnoveterinary medicine can be integrated with contemporary animal health and production systems. By integrating age-old practices and knowledge with modern western science, the book aims to promote sustainable and organic livestock farming. It highlights the advantages of using polyherbal feed additives, providing natural living conditions for animals, and utilizing herbal derivatives to promote growth and health in animal nutrition. With emphasis on the economic and ecological benefits, Ethnoveterinary Practices in Animal Agriculture seeks to preserve and revitalize traditional veterinary knowledge, which is at risk of disappearing due to rapid technological, environmental, and socioeconomic changes. Written by a team of global, interdisciplinary experts, this work is both a useful summary of the existing literature in this area and fascinating starting point for new research.

  • Micro(nano)plastics in Organ Systems

    Health Impacts, Challenges, and Future Prospects
    • 1st Edition
    • Charan Singh + 4 more
    • English
    Micro(nano)plastics in Organ Systems: Health Impacts, Challenges, and Future Prospects comprehensively discusses the impact of micro(nano)plastics on human health, analyzing their sources, classification, and exposure pathways, while also exploring their interactions with biological systems, their potential effects on various organ systems, and concerns related to bioaccumulation and toxicity. The book begins with an in-depth analysis of their classification, sources, and exposure pathways, and progressing through interactions with biological systems and the resulting toxicological effects. Furthermore, the book delves into recent advances in detection technologies, the development of more sustainable advances such as bioplastic-based nanoparticles, and the need for regulatory frameworks.The text meticulously examines the implications of these particles on various organ systems—including the gastrointestinal, respiratory, cardiovascular, renal, neurological, reproductive, and metabolic systems—while addressing critical issues such as bioaccumulation, immunological responses, and their potential harmful impact on health. It is an essential resource for toxicologists, environmental scientists, healthcare professionals, public health advocates, and others interested in the implications of micro(nano)plastics on health.

  • Cellular Senescence

    Mechanisms, Disease Links, and Therapeutic Opportunities
    • 1st Edition
    • Kishor Pant + 1 more
    • English
    Cellular Senescence: Mechanisms, Disease Links, and Therapeutic Opportunities provides a comprehensive resource on cellular senescence and its significance as a fundamental driver of various diseases. This reference consolidates mechanistic insights and clinical relevance, bridging the gap between basic science and translational relevance to explore both the molecular underpinnings of senescence, and its implications for therapeutic innovation, highlighting how targeting senescent cells may reshape the future of medicine. The book systematically covers foundational concepts including senescence triggers, molecular pathways, and detection methods, progressing through disease-specific chapters on cancer, metabolic disorders, liver diseases, fibrosis, cardiovascular disease, neurodegenerative conditions and chronic inflammation. It highlights the paradoxical roles of senescent cells alongside emerging therapeutic strategies such as senolytics and senomorphics. Each chapter integrates current research, clinical insights, and translational applications. Step-by-step procedures, case studies, and learning objectives are also included throughout to aid understanding.Cellul... Senescence: Mechanisms, Disease Links, and Therapeutic Opportunities enhances understanding of the complex biology underlying this key cellular process. It is an ideal resource for cell biologists, biomedical researchers, clinicians, and graduate students in related areas who are looking to advance their understanding of cellular senescence and how it may be harnessed to treat a variety of diseases.

  • Microfluidic Platforms for Rapid Antibiotic Susceptibility Testing (AST)

    Accelerating Diagnosis and Optimizing Antimicrobial Therapy
    • 1st Edition
    • Raju Khan + 4 more
    • English
    Microfluidic Platforms for Rapid Antibiotic Susceptibility Testing (AST): Accelerating Diagnosis and Optimizing Antimicrobial Therapy provides a comprehensive and interdisciplinary exploration of microfluidic technologies as transformative tools in the fight against antimicrobial resistance (AMR). By integrating foundational knowledge of AMR and microfluidics with cutting-edge research, it offers readers an in-depth understanding of how microfluidic systems enable rapid, precise, and cost-effective antibiotic susceptibility testing (AST). The book addresses both the scientific principles and practical applications of these technologies, emphasizing their potential to revolutionize diagnostics, personalize treatment, and improve global health outcomes amidst the growing threat of drug-resistant infections. Organized into five key parts, the book begins with an overview of the global challenge of antimicrobial resistance and the fundamental principles of microfluidics in biomedical contexts. It then delves into various microfluidic platforms for AST, including continuous flow and droplet-based systems, as well as single-cell trapping techniques. Subsequent chapters focus on diverse detection methods—optical, electrochemical, and acoustic—for monitoring bacterial growth and antibiotic response. The book further explores specialized approaches such as paper-based point-of-care devices, biosensing strategies, and personalized medicine applications. The final section addresses clinical translation, covering validation, regulatory considerations, device design, automation, emerging technologies, ethical guidelines, and future perspectives on microfluidic AST’s role in combating antimicrobial resistance worldwide.

  • The NeuroComplex Interaction of Appetite Regulation

    Brain, Body and Environment
    • 1st Edition
    • Nasrollah Moradikor + 1 more
    • English
    The NeuroComplex Interaction of Appetite Regulation: Brain, Body and Environment presents the latest research on why we eat, what makes us hungry, and how our brain controls our cravings. The book covers the data for how the brain, hormones, and different factors such as stress, the environment, and even food itself affects our desire to eat. Written for academics and researchers, this book helps facilitate a comprehensive understanding on how the brain influences appetite regulation, allowing readers to understand how neurobiological mechanisms can help treat patients involved with obesity, eating disorders, or other related conditions.Readers will find this to be a reliable resource that connects current neuroscience research with practical applications in appetite and behavior.

  • Mathematical Foundations of Physiology, Medicine, and Health Sciences

    • 1st Edition
    • Dhanjoo N. Ghista + 3 more
    • English
    Mathematics and Biomedical Engineering in Medicine, Physiology and Health Sciences is a visionary book, whose purpose is to demonstrate how fundamental mathematics and biomedical engineering can be incorporated into physiology, medicine, and health sciences teaching, research,and clinical practice to make these disciplines more quantitative and computational, and hence more explanatory and informative. The book also provides more quantitative formulation of medical procedures, towards supporting the growing field of precision medicine.

  • Precision Functional Mapping

    From Human Neuroscience to Engineering
    • 1st Edition
    • Prantik Kundu
    • English
    Precision Functional Mapping explores next-generation functional neuroimaging techniques, focusing on the pursuit of accuracy and scalability in understanding the human brain, to the extent of enabling individual-subject level insights on brain function. Precision Functional Mapping: From Neuroscience to Engineering provides a clear and practical guide to implementing precision functional mapping. It uniquely balances the theoretical foundations of advanced functional neuroimaging with actionable strategies for implementation. With an emphasis on precision, scalability, and practical relevance, it addresses both current limitations and future possibilities in the field. By focusing on underexplored areas such as sparsity, temporal precision, and regulatory considerations, it offers a fresh perspective. Readers interested in neuroscience research, clinical applications, or technology development will find this book gives them tools and insights to push the boundaries of what is possible with functional neuroimaging.

  • Endoscopic/Robotic Thyroidectomy Surgery

    Using the Gasless Unilateral Axillary Approach
    • 1st Edition
    • Chuanming Zheng + 1 more
    • English
    Endoscopic/Robotic Thyroidectomy Surgery: Using the Gasless Unilateral Axillary Approach is a comprehensive and systematic resource on endoscopic/robotic thyroidectomy using the gasless unilateral axillary approach comprehensive and systematically presented resource on the gasless axillary approach to endoscopic/robotic thyroidectomy. It includes a detailed introduction to all aspects of surgical treatment including anesthesia coordination and robotic surgery. The book provides practical guidance on postoperative complication management and postoperative care and describes specific methods for technical simulation training and functional exercises. While many journal papers on specific aspects of this surgical approach have been published, no book is currently available.

  • Alternative Splicing

    Recent Advances in Health and Disease
    • 1st Edition
    • Sayeed ur Rehman A. Kalam + 1 more
    • English
    Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances, and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics.This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.

  • Herbal Nanoparticles

    Sources and Applications
    • 1st Edition
    • Santosh Kumar Upadhyay + 1 more
    • English
    Herbal Nanoparticles: Sources and Applications provides a comprehensive overview of the evolving field of herbal nanoparticles, which merges traditional plant-based medicine with innovative nanotechnology.The book starts with an introduction to herbal nanoparticles, followed by detailed chapters on synthesis methods, botanical sources, and green approaches to nanoparticle production. It then explores physicochemical properties and advanced characterization techniques essential for understanding these particles.The following chapters focus on practical applications, from crop improvement, enzyme technology, and waste valorization to drug delivery, targeted therapy, and treatment of various diseases such as cancer and neurological disorders. Safety, toxicology, and regulatory challenges are also discussed, along with dedicated chapters on the commercialization and future research directions.With detailed discussions of formulation techniques, nanosafety, and practical applications in healthcare, agriculture, and biotechnology, this book is a valuable resource for researchers, advanced students, and professionals interested in herbal nanotechnology and its applications across a wide range of fields.

  • Novel Technologies for the Processing and Preservation of Muscle Foods

    • 1st Edition
    • Alaa El-Din A. (Aladin) Bekhit + 1 more
    • English
    Novel Technologies for Processing and Preservation of Muscle Foods explores emerging and innovative technologies in the food industry and their role in enhancing the quality, safety, and sustainability of meat, fish, and seafood. Each chapter explores the biochemistry and microbiology underlying these technologies, their applications in the food industry, and the challenges and successes encountered in commercial settings. From improving tenderness and digestibility to developing hypoallergenic and functional foods, the book highlights the transformative potential of cutting-edge methods to meet the evolving demands of consumers and the food industry. Structured to provide a thorough understanding of both theory and practical applications, this book covers a wide range of topics, including the use of robotics and automation in meat processing, the development of biodegradable packaging, and the implications of Industry 4.0 technologies in food production. With contributions from leading experts, Novel Technologies for Processing and Preservation of Muscle Foods not only addresses existing gaps in knowledge but also proposes future directions for research and innovation. This timely resource will serve as a key reference for researchers, students, and professionals interested in the latest advancements in the processing and preservation of meat, fish, and seafood.

  • Biology

    A Human Health Perspective
    • 1st Edition
    • Harry E. Peery + 2 more
    • English
    Biology: A Human Health Perspective offers important medical case histories and complex color illustrations, interacts with the reader, and asks questions throughout. Sections cover the basic chemistry of biology and cell origins, and energy and protein processing before discussing cell reproduction, genetics, evolution, and their place in public healthcare. Clinical applications and medical terminology are also included across chapters, and pioneering medical developments such as holographic surgery, robotic neurosurgery, and tractography are featured.This textbook, along with supporting ancillary materials such as PowerPoint slides, solution manuals and quiz banks is a vital resource for all undergraduate students studying biology or for those looking to develop a career in a health profession who need a basic understanding of the field.

  • Microbiome and Tumorigenesis

    Dysbiosis in Different Cancers
    • 1st Edition
    • Volume 1
    • Sanjana Mehrotra + 1 more
    • English
    Microbiome and Tumorigenesis: Dysbiosis in Different Cancers examines the intricate relationship between the human microbiome and cancer. Organized into three parts, the book opens with the conceptual and ecological foundations of the human microbiome and dysbiosis, tracing how microbial imbalance contributes to tumor development. The second part examines how microbiome dysbiosis drives carcinogenesis, covering its effects on tumor immunity, the dual role of microbial metabolites as both oncogenic drivers and protective effectors, and the contribution of fungal and viral dysbiosis to cancer development and treatment. The third part surveys dysbiosis across organ-specific cancers, including gastrointestinal, skin, oral, lung, head and neck, liver, and gynecologic malignancies. This book is a valuable resource for researchers, clinicians, and students seeking to understand the complex interplay between the microbiome and cancer, with insights into potential therapeutic strategies and future research directions.

  • Insect Proteins as Sustainable Food Ingredients

    Nutrition, Processing and Consumer Acceptance
    • 1st Edition
    • Ronghai He
    • English
    In the quest for sustainable food solutions alternative to traditional proteins, insects are emerging as a compelling option. Insect Proteins as Sustainable Food Ingredients: Nutrition, Processing and Consumer Acceptance, explores the nutritional composition of various insect species from around the world such as the black soldier fly, cricket, mealworm and silkworm, and sheds light on their high protein, low-carbon, low emission, sustainable environmental benefits while providing insight into nutrition and health. With consumers more likely to eat processed insect products rather than whole body insects, Insect Proteins as Sustainable Food Ingredients: Nutrition, Processing and Consumer Acceptance, examines insect protein extract as a raw materials and how it can significantly reduce consumers’ negative perception of insects as a food source. Experts in the filed introduce readers to the production and processing of insect protein flours, concentrates, isolates and hydrolysates and highlight the defatting, grinding, purification, drying and extraction technologies for insect proteins to be used for product innovation. Also addressed are flavor and sensory properties and ways to measure consumer acceptance of insect-based products. The book concludes by reviewing potential safety and allergy concerns and provides suggestions on how to establish a food safety regulatory framework.

  • On Human Nature

    Biology, Psychology, Ethics, Politics, and Religion
    • 2nd Edition
    • Michel Tibayrenc
    • English
    On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human biological and cultural diversity and its adaptative significance through an extensive selection of representative chapters. Edited by renowned expert Michel Tibayrenc, this second edition features updates to all major sections of the first edition and brings novel chapters covering critical advancements in human biology, psychology, behavior, ethics, and culture. It is accessible not only to specialists, but also to students, professors, industry professionals, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.The book brings together specialists from various fields, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. A globally diverse and interdisciplinary team of experts has been carefully selected to cover the breadth of topics enclosed.

  • Network Pharmacology

    Exploring New Horizons in Drug Discovery
    • 1st Edition
    • Veeranoot Nissapatorn + 4 more
    • English
    Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach—which examines the intricate interactions between disease targets and metabolites—offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.

  • The Inflammatory Ecosystem and Inflammazones

    Mapping the Complex Terrain of Inflammatory Diseases
    • 1st Edition
    • Erwei Song + 1 more
    • English
    The Inflammatory Ecosystem and Inflammazones: Mapping the Complex Terrain of Inflammatory Diseases offers a groundbreaking framework for understanding inflammation across multiple spatial and molecular levels. The book introduces the concept of distinct inflammazones—local, regional, distal, and systemic—and explores how their interactions influence disease development, progression, and resolution. This holistic approach integrates cellular, molecular, microbiome, and systemic responses, addressing a critical gap in current knowledge and advancing diagnostics and therapies for diseases like autoimmunity and cancer. The book is organized into six sections, starting with foundational principles and progressing through mechanisms of local, regional, and systemic inflammazones.It covers key components such as cytokines, chemokines, immune cells, and the roles of non-immune cells like fibroblasts and epithelial cells. The final sections focus on systems-level insights, including inflammaging, metabolism, and multi-omics technologies, culminating in strategies for personalized medicine and clinical translation. Each chapter combines cutting-edge research with clinical relevance, making complex concepts accessible and actionable.

  • Tissue Organization in Development

    • 1st Edition
    • Volume 171
    • English
    Tissue Organization in Development explores how cells coordinate, communicate, and arrange themselves to build functional tissues during embryonic and postnatal development. The book brings together current perspectives on the molecular, cellular, and mechanical principles that govern tissue patterning, morphogenesis, and structural organization across developing systems. Covering key topics such as cell fate specification, cell–cell interactions, extracellular matrix dynamics, polarity, migration, and tissue remodeling, it highlights how complex biological form emerges from coordinated developmental processes. This volume provides a valuable resource for researchers, students, and professionals interested in developmental biology, cell biology, and tissue formation.

  • Current State of Alzheimer's and Parkinson's Disease Research and its Pharmacology

    • 1st Edition
    • Volume 108
    • English
    Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Toxoplasma Gondii

    The Model Apicomplexan - Perspectives and Methods
    • 4th Edition
    • Louis M. Weiss + 1 more
    • English
    Toxoplasma Gondii: The Model Apicomplexan - Perspectives and Methods, Fourth Edition offers a comprehensive approach and balance between historical research, new developments, and innovative approaches to Toxoplasma gondii research. Completely updated and revised, the new Edition aims to provide a better understanding of the structure, genetic diversity, and population biology of T. gondii. The book details the immunology, molecular, and cellular biology of Toxoplasma gondii combined with new molecular techniques, methods, and resources for working with this pathogen. It also offers the latest information concerning epidemiology, diagnosis, treatment, and prevention of toxoplasmosis.With contributions from leading experts in the field, this is an essential one-stop resource for a wide range of researchers, scientists, and clinicians engaged in the study of T. gondii and toxoplasmosis.

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