Synthetic Biology in Medicine
Tools and Transformative Therapies
- 1st Edition - January 1, 2027
- Latest edition
- Author: Xie Zhen
- Language: English
Synthetic Biology in Medicine is divided into seven chapters, covering the design and optimization of artificial biological components, gene editing systems, principles for design… Read more
Description
Description
Key features
Key features
- Provides full-chain knowledge coverage of medical synthetic biology, systematically and comprehensively introducing everything from the design of underlying components to top-level therapeutic strategies
- Contains many application cases related to clinical practice and industry, offering references for solving industrial pain points. Each chapter starts with real cases (such as the design details of COVID-19 mRNA vaccines), directly addressing the core of the technology. It provides reusable technical paths and risk avoidance strategies for scientific research transformation and enterprise R&D
- Integrates knowledge from multiple fields including biology, computer science (e.g., language model prediction of 5'UTR (a region of messenger RNA (mRNA) that is upstream of the protein-coding sequence), and materials science (e.g., nanoparticle carriers). It introduces the progress of synthetic biology in the medical field from an interdisciplinary perspective, making it suitable for interdisciplinary readers
Readership
Readership
Table of contents
Table of contents
1. The Rise and Development of Medical Synthetic Biology
2. Application Fields of Medical Synthetic Biology
3. Research Ideas of Medical Synthetic Biology
4. Prospects and Challenges of Medical Synthetic Biology
Chapter 2: Design and Optimization of Artificial Biological Components
5. Introduction to Biological Components
6. Rational Design of Biological Components
7. Intelligent Design of Biological Components
8. Development Trends in the Design and Optimization of Biological Components
Chapter 3: Gene Editing
9. DNA Editors
10. RNA Editors
11. Prime Editors
12. Prospects
Chapter 4: Artificial Gene Circuits
13. Mechanisms of Gene Circuits
14. Principles for Constructing Gene Circuits
15. Classical Gene Circuits
16. Computer-Assisted Strategies for Gene Circuit Construction
Chapter 5: Cell Engineering
17. Immune Cell Engineering
18. Stem Cell-Derived Cell Engineering
19. Bacterial Engineering
20. Summary
Chapter 6: Delivery Systems for Artificial Biomolecules
21. Viral Delivery Vectors
22. Non-Viral Delivery Vectors
23. Medical Application Scenarios of Different Delivery Vectors
24. Summary and Outlook
Chapter 7: Prospects and Challenges of Synthetic Biology in Drug Development
25. Clinical Application Prospects of Synthetic Biology Technologies
26. Case Studies of Synthetic Biology in Drug Development
27. Challenges Facing Synthetic Biology in Drug Development
Product details
Product details
- Edition: 1
- Latest edition
- Published: January 1, 2027
- Language: English
About the author
About the author
XZ
Xie Zhen
Dr Xie Zhen is based at the Institute of Information Processing, Tsinghua University and the Center for Synthetic and Systems Biology, Tsinghua University. He is a Tenured Associate Professor. Dr Zhen is Chair of the Synthetic Biotechnology Branch of the China Medicinal Biotechnology Association; Member of the Professional Committee of Bioinformatics and Artificial Life of the Chinese Association for Artificial Intelligence; and a Member of the Synthetic Biology Professional Committee of the Chinese Society of Biotechnology.
His research interests include: synthetic biology, cancer therapy, and the design and control of artificial molecular machines