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Elsevier

CRISPR Therapeutics Delivery Strategies

  • 1st Edition - March 1, 2027
  • Latest edition
  • Editor: Prashant Kesharwani
  • Language: English

CRISPR Therapeutics Delivery Strategies is a structured and comprehensive resource in the rapidly evolving field of CRISPR technology. As CRISPR-Cas systems translate to therap… Read more

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Description

CRISPR Therapeutics Delivery Strategies is a structured and comprehensive resource in the rapidly evolving field of CRISPR technology. As CRISPR-Cas systems translate to therapeutics, this reference provides critical insights into the challenges and advancements in effective delivery mechanisms. The book captures the essence of CRISPR's transformative potential in gene therapy, targeted cancer treatments, and personalized medicine, while also highlighting the importance of innovative delivery strategies to overcome existing barriers. The contents of the book offers a systematic exploration of CRISPR technology, beginning with foundational concepts and progressing to targeted drug delivery strategies. Each chapter explore specific applications, including CRISPR in cancer therapy, gene editing for rare diseases, and overcoming delivery barriers such as the blood-brain barrier. Additionally, ethical and regulatory considerations are addressed, providing a holistic view of the current landscape and future directions in CRISPR research. CRISPR Therapeutics Delivery Strategies serves as an essential resource for students, researchers, and professionals in the fields of pharmacology, biotechnology, and gene therapy. By compiling cutting-edge research and expert perspectives, this reference helps pharmaceutical scientists to navigate the complexities of CRISPR technology and its applications.

Key features

  • Offers a comprehensive coverage of CRISPR-Cas technology from foundational concepts to advanced applications
  • Covers in-depth exploration of innovative CRISPR-based drug delivery approaches
  • Presents insights into ethical, regulatory, and safety considerations surrounding CRISPR technology

Readership

Pharmaceutica scientists in academia, advanced students at PhD level

Table of contents

SECTION 1: FUNDAMENTALS OF CRISPR TECHNOLOGY: BREAKTHROUGH IN GENETIC ENGINEERING

1.Introduction to CRISPR: Overview and historical milestones in gene editing

2. Basics of drug delivery and gene editing

3. Understanding the science behind CRISPR mechanism

4. Potential of CRISPR technology in drug delivery

5. Role of CRISPR in targeted delivery: Synergy of nanoparticles and CRISPR

SECTION 2: CRISPR BASED TARGETED DRUG DELIVERY STRATEGIES

6. Viral Vectors and CRISPR: A Common Approach to Drug Delivery

7. Non-Viral Delivery Systems: CRISPR and Alternative Carriers

8. CRISPR in RNA Drug Delivery: mRNA and Beyond

SECTION 3: APPLICATIONS OF CRISPR BASED TARGETED THERAPEUTICS

9. CRISPR in Cancer Drug Delivery: Precision Medicine at Work

10. CRISPR-Based Gene Editing for Rare Diseases

11. Delivering CRISPR to the Brain: Overcoming the Blood-Brain Barrier

12. Immunomodulation and CRISPR in Drug Delivery

13. CRISPR in Vaccine Development and Delivery

14. Overcoming Delivery Barriers: Stability, Bioavailability, and Half-Life

SECTION 4: CHALLENGES, ETHICAL AND REGULATORY ASPECTS

15. CRISPR for Chronic Diseases: Challenges in Long-Term Therapeutic Approaches

16. Safety and Ethical Concerns in CRISPR Drug Delivery

17. Legal, and Social Implications of CRISPR in Drug Delivery

18. Regulatory Frameworks and Oversight in CRISPR-Based Therapies

SECTION 5: FUTURE DIRECTIONS, CLINICAL TRIALS, AND CONCLUSION

19. CRISPR in Stem Cell Therapy: A Path to Regenerative Medicine

20. Clinical Trials: The Reality of CRISPR Drug Delivery

21. Innovative CRISPR Delivery Strategies: Future Directions

22. Conclusion: The Transformative Potential and Impact of CRISPR Drug Delivery Systems in Healthcare and Pharmaceutical Industries

Product details

  • Edition: 1
  • Latest edition
  • Published: March 1, 2027
  • Language: English

About the editor

PK

Prashant Kesharwani

Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India. He has more than a decade of teaching, research, and industrial experience across various countries. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has published many articles in well-reputed journals and a large number of books. He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, and “SERB-Ramanujan Fellowship Award”. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.

Affiliations and expertise
Dr. Harisingh Gour Vishwavidyalaya University