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Elsevier

Management of Chronic Kidney Disease and Its Complications

  • 1st Edition - February 1, 2027
  • Latest edition
  • Editors: Thakur Gurjeet Singh, Rajwinder Kaur, Rupinder Kaur, Sumitha Elayaperumal, Nitin Gupta
  • Language: English

Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse compli… Read more

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Description

Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.

The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.

Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

Key features

  • Explores the molecular, genetic, and epigenetic mechanisms underlying CKD and its diverse complications, providing a comprehensive understanding of disease pathophysiology
  • Examines the diagnosis and management of cardiovascular, metabolic, neurological, hematological, and urologic complications associated with CKD to support holistic patient care
  • Discusses emerging therapeutic approaches including precision medicine, regenerative therapies, gut microbiota modulation, and the application of artificial intelligence and machine learning in early detection and treatment
  • Addresses the unique challenges and management strategies for special populations such as pediatric, geriatric, and pregnant patients with CKD
  • Integrates evidence-based pharmacological, nutritional, and lifestyle interventions alongside psychosocial considerations to optimize clinical outcomes and quality of life for CKD patients

Readership

Nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research

Table of contents

1. Introduction to Chronic Kidney Disease (CKD)

2. Genetic Contributions to the Development of Kidney Disease

3. Diagnostic Evaluation of CKD

4. Molecular Basis of CKD (Pathways, role of inflammation and oxidative stress)

5. Complications of CKD

6. Cardiovascular complications and its management (Vascular calcification)

7. Vascular Diseases (Renovascular Disease; Thrombotic Microangiopathies)

8. Hematological complications and its management

9. Metabolic complications and its management (CKD-MBD)

10. Gastric complications and its management

11. Neurological complications (eg; Dystonia)

12. Hypertension in CKD: Pathogenesis and Management

13. Diabetic Nephropathy: Pathophysiology and Management/Treatment Strategies

14. Glomerular Diseases

15. Tubulointerstitial Diseases

16. Risk of Infections in CKD (Urinary Tract Infections; Sepsis Management)

17. Management strategies in CKD (Pharmacological Interventions and Lifestyle modifications)

18. Nutritional Management in CKD (Dietary Restrictions and Nutritional Supplements)

19. CKD in Pediatric population (Special Considerations and Challenges)

20. CKD in Geriatric population (Treatment Considerations and Challenges)

21. CKD in Pregnancy

22. Psychosocial Aspects of Chronic Kidney Disease: Addressing Mental Health and Quality of Life

23. Advances in Understanding and Treating Cystic Kidneys

24. Renal Replacement Therapy

25. Herbal approaches in the management of CKD

26. Emerging Research and Therapies /interventions

27. Epigenetics and CKD

28. Precision Medicine in CKD-Genetic and Epigenetic Insights

29. Gut Microbiota and CKD- A New Therapeutic Target

30. Regenerative Medicine in CKD:-Stem Cells and Tissue Engineering

31. Artificial Intelligence and Machine Learning in Early CKD Detection and Management

32. Kidney Disease Secondary to Urologic Conditions: Stones, Calcinosis, Obstruction, and More

Product details

  • Edition: 1
  • Latest edition
  • Published: February 1, 2027
  • Language: English

About the editors

TS

Thakur Gurjeet Singh

Dr. Thakur Gurjeet Singh is a pharmacology researcher with extensive graduate training in clinical and preclinical drug development. His work focuses on the neuroprotective mechanisms of pharmacological preconditioning in neurodegenerative disorders such as Alzheimer’s disease, Parkinsonism, stroke, epilepsy, and dementia. He has investigated key protective pathways involving adenosine, opioids, CGRP, calcium signaling, protein kinase-C, heat shock proteins, and MAP kinase. His research also explores novel therapeutic pathways using agents such as morphine and capsaicin, with additional expertise in mechanistic studies of substance dependence, including nicotine, alcohol, and morphine addiction. Dr. Singh’s core competencies include animal model development and validation, anesthetic and preconditioning techniques, histopathological analysis, and behavioral data evaluation. His broader interests include ALS, stem cell therapy, and movement disorders such as tardive dyskinesia.

Affiliations and expertise
Chitkara University, Punjab, India

RK

Rajwinder Kaur

Rajwinder Kaur is Assistant Dean of Pharm D (Academics) at Chitkara College of Pharmacy, Chitkara University, Punjab, India. She has extensive experience in teaching and research and has held academic and research positions, including appointment as a DST Women Scientist at Panjab University, Chandigarh. Her research focuses on computational drug design, fused heterocyclic compounds, nanomedicine, and the application of artificial intelligence in pharmaceutical research, with particular interests in inflammation, asthma, and neurological disorders. Dr. Kaur has contributed extensively to the scientific literature through scholarly publications, book chapters, and editorial work. She is actively involved in academic and research initiatives that promote innovation in pharmaceutical sciences and interdisciplinary drug discovery. She is a Senior Member of the Hong Kong Chemical, Biological & Environmental Engineering Society (HKCBEES) and a Life Member of the Indian Pharmacy Graduate Association (IPGA).
Affiliations and expertise
Chitkara College of Pharmacy, Chitkara University, Punjab, India

RK

Rupinder Kaur

Dr. Rupinder Kaur is Assistant Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. Her research interests revolve around management and advancement of pharmacotherapeutic approaches towards kidney diseases.

Affiliations and expertise
Assistant Professor, Chitkara College of Pharmacy, Chitkara University, Punjab, India

SE

Sumitha Elayaperumal

Dr. Sumitha Elayaperumal is Assistant Professor at the JSS Academy of Higher Education and Research, Mysore, Karnataka. Her specialization is on molecular diagnosis of Coagulation platelet, thrombotic, and oncology disorders.

NG

Nitin Gupta

Dr. Nitin Gupta is Director for Neelam Hospital, Rajpura, Punjab. Dr. Gupta is a leading urologist, laparoscopy, and renal transplant surgeon with a strong interest in advanced laparoscopic procedures. He has performed over 5000 endourological procedures, including more than 1200 PCNLs and over 1500 advanced laparoscopic surgeries such as laparoscopic donor nephrectomy, pyeloplasty, and nephrectomy.

Affiliations and expertise
Director, Neelam Hospital, Rajpura, Punjab, India