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Elsevier

Books in Life sciences

  • Platelets

    • 3rd Edition
    • Alan D. Michelson
    • English
    Platelets - winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine - is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource.

  • Workbook for Pharmacology for Pharmacy Technicians

    • 2nd Edition
    • Kathy Moscou + 1 more
    • English
    Specially designed to parallel the material in Pharmacology for Pharmacy Technicians, 2nd Edition, this helpful workbook provides in-depth study and review of the ASHP content requirements for pharmacology and anatomy and physiology. Its user-friendly format and engaging learning exercises help you understand both basic and advanced pharmacologic concepts. Practical activities allow you to apply your knowledge to real-world scenarios.

  • Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

    Models in Discovery and Translation
    • 1st Edition
    • Gerard Socie + 1 more
    • English
    Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemi... (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically similar but not identical donor. This procedure is commonly performed for people with diseases of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog. These animal models have been essential in developing transplant protocols, including preclinical testing of conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant species differences between humans and animal models that must be considered when relating animal model studies to clinical allogeneic HSCT scenarios.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 68
    • English
    Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Neurological Rehabilitation

    • 1st Edition
    • Volume 110
    • Michael P. Barnes + 1 more
    • English
    Neurological Rehabilitation is the latest volume in the definitive Handbook of Clinical Neurology series. It is the first time that this increasing important subject has been included in the series and this reflects the growing interest and quality of scientific data on topics around neural recovery and the practical applications of new research. The volume will appeal to clinicians from both neurological and rehabilitation backgrounds and contains topics of interest to all members of the multidisciplinary clinical team as well as the neuroscience community. The volume is divided into five key sections. The first is a summary of current research on neural repair, recovery and plasticity. The authors have kept the topics readable for a non-scientific audience and focused on the aspects of basic neuroscience that should be most relevant to clinical practice. The next section covers the basic principles of neurorehabilitation, including excellent chapters on learning and skill acquisition, outcome measurement and functional neuroimaging. The key clinical section comes next and includes updates and reviews on the management of the main neurological disabling physical problems, such as spasticity, pain, sexual functioning and dysphagia. Cognitive, emotional and behavioural problems are just as important and are covered in the next section, with excellent chapters, for example, on memory and management of executive dysfunction. The final part draws the sections on symptom management together by discussing the individual diseases that are most commonly seen in neurorehabilitation and providing an overview of the management of the disability associated with those disorders. The volume is a definitive review of current neurorehabilitation practice and will be valuable to a wide range of clinicians and scientists working in this rapidly developing field.

  • Clinical Pharmacology During Pregnancy

    • 1st Edition
    • English
    Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are covered, as are research issues, including clinical trial design and ethical considerations.

  • Bioinformatics of Behavior: Part 2

    • 1st Edition
    • Volume 104
    • English
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Bioinformatics of Behavior: Part 1

    • 1st Edition
    • Volume 103
    • English
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Robotics and Automation in the Food Industry

    Current and Future Technologies
    • 1st Edition
    • Darwin G Caldwell
    • English
    The implementation of robotics and automation in the food sector offers great potential for improved safety, quality and profitability by optimising process monitoring and control. Robotics and automation in the food industry provides a comprehensive overview of current and emerging technologies and their applications in different industry sectors.Part one introduces key technologies and significant areas of development, including automatic process control and robotics in the food industry, sensors for automated quality and safety control, and the development of machine vision systems. Optical sensors and online spectroscopy, gripper technologies, wireless sensor networks (WSN) and supervisory control and data acquisition (SCADA) systems are discussed, with consideration of intelligent quality control systems based on fuzzy logic. Part two goes on to investigate robotics and automation in particular unit operations and industry sectors. The automation of bulk sorting and control of food chilling and freezing is considered, followed by chapters on the use of robotics and automation in the processing and packaging of meat, seafood, fresh produce and confectionery. Automatic control of batch thermal processing of canned foods is explored, before a final discussion on automation for a sustainable food industry.With its distinguished editor and international team of expert contributors, Robotics and automation in the food industry is an indispensable guide for engineering professionals in the food industry, and a key introduction for professionals and academics interested in food production, robotics and automation.

  • Nonisotopic DNA Probe Techniques

    • 1st Edition
    • Larry J. Kricka
    • English
    Recently many nonisotopic methods of probing specific DNA sequences have been developed as replacements for radioactive labels, such as 32phosphorous and 125iodine. This book brings all of these new methods together in one convenient, easily accessible source. It enables researchers to select the nonisotopic method best suited to their application and to use it to maximum advantage by following the straightforward instructions provided.This book contains chapters on colorimetric, bioluminescent, chemiluminescent, fluorescent, and time-resolved fluorescent detection methods. Each chapter has been written by the inventor or developer of a particular nonisotopic method and thus provides an expert account of the method. Each chapterpresents useful background information and detailed, step-by-step, easy-to-follow, experimental procedures for labeling and detection.

  • The Bacteria

    Molecular Basis of Bacterial Pathogenesis
    • 1st Edition
    • Bozzano G Luisa
    • English
    The reviews in this volume deal with questions of the mechanisms of pathogenesis and with organisms that have only recently been extensively studied on the molecular level.**The introductory section presents an overview of pathogenesis, emphasizing common elements and genetic mechanisms of regulation and a review on the population genetics of bacterial pathogenesis. The second section deals with the regulation of synthesis of surface components and their role in the colonization of the host and/or of the host immune systems. The third section covers the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies of the role of bacterial toxic products in pathogenesis.

  • Designing Antibodies

    • 1st Edition
    • Ruth Mayforth
    • English
    Designing Antibodies provides a compilation of research in the design of antibodies. It describes the techniques used in antibody design, the kinds of antibodies generated through modern techniques, and their applications in medicine and science. The book begins with an overview of the humoral immune system and of antibody structure, function, and biosynthesis, which sets the stage for the subsequent discussions of developments in antibody technology. The remaining chapters discuss the making of monoclonal antibodies; the design of antibodies for human therapy; the connection of antibodies (either chemically or genetically) to other potentially therapeutic effector molecules such as toxins, enzymes, or even an antibody of another specificity; idiotypes and anti-idiotypic antibodies; and the ability of antibodies to functionally mimic enzymes and mediate catalysis. It is hoped that, in addition to illustrating the progress of research in antibody design, the various creative and innovative approaches reviewed in this book will be modified or will stimulate new ideas that will spur the research and application of designer antibodies.

  • Keratinization

    A Survey of Vertebrate Epithelia
    • 1st Edition
    • Nancy Alexander
    • English
    Keratinization: A Survey of Vertebrate Epithelia illustrates the salient features of the epithelial portion of the skin and its appendages in each class of vertebrates, with emphasis on the ultrastructural and functional aspects. Divided into six chapters, this book begins with the general process of keratinization. Then, epithelial differentiation and specialization in the various classes of vertebrates are described. Classes of vertebrates considered are fish, amphibian, reptilian, avian, and mammalian. This treatise is designed to provide an introduction to the study of vertebrate skin and to stimulate professional investigators to delve into its mysteries.

  • Planar Lipid Bilayers

    Methods and Applications
    • 1st Edition
    • W. Hanke + 1 more
    • English
    Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Methods of constructing artificial membranes (planar lipid bilayers) from the main components of cell membranes (lipids) date from the early 1960s.Planar bilayers offer direct, quantitative experimental approaches to the study of membranes of precisely determined composition which can be manipulated by the experimenter. Pore-forming molecules, transporter molecules, ATP-dependent enzymes and other entities can be incorporated into the bilayers to simulate biological functions.Reconstitu... of such functions in this way remains a key final step in attributing a functional role to purified cell membrane proteins.This book aims to demystify these techniques and begins with a broad overview of the development of the subject before dealing with the protocols involved.Key references are provided at the end of the book together with a list of suppliers.

  • Neurotransmitter Release the Neuromuscular Junction

    • 1st Edition
    • Francesco Clementi
    • English
    Neurotransmitter Release: The Neuromuscular Junction is a collection of papers presented at a small meeting organized in the University of Milan to honor Bruno Ceccarelli. Ceccarelli was particularly interested in the structure and functioning of the neuromuscular junction and spent the rest of his career characterizing the process of neurotransmitter release, and eventually providing the strongest available support for the widely accepted ""vesicle hypothesis"" of neurotransmitter release. The meeting was intended to gather as many scientists who had been directly in touch with Bruno as possible and to discuss together problems of Bruno's interest. Organized into 20 chapters, the book first discusses the organelles of distinct secretory pathways involved in distinct types of neuronal signaling, such as synapsins, synaptophysin , and synaptobrevin. It then examines the role of coated vesicles, acetylcholine compartments, and potassium and calcium channels on neurotransmission processes. Other topics considered are the regeneration of nerve-evoked neurotransmission; the single-channel recordings of KNa in avian sensory neurons; the modulation of voltage-dependent calcium currents in identified snail neurons; and the agonistic/antagonist... action of calcium channel in mammalian peripheral neurons. Cross-talks between receptors coupled to calcium currents and between different intracellular signaling are provided in the last chapters of the book. These chapters also look into the relevance of lipoxygenase metabolites of arachidonic acid to cell-to-cell communication in the central nervous system. This book is an invaluable source for scientists, researchers, and students who are interested in basic neurology.

  • Social Insects V1

    • 1st Edition
    • Henry Hermani
    • English
    Social Insects, Volume I is a part of a four-volume discourse and collection of research on insect sociobiology. This volume covers the “modern theory” with certain concepts of insect sociality, particularly through genetic, behavioral, and evolutionary pathways. This book consists of eight chapters, which mostly deal with the sociality of insects and other aspects. The first chapter provides an introduction to the subject of insect sociality. Topics in this chapter include definition of sociality, types of social insects, and insect sociobiology. The next chapter focuses on the origin and evolution of insect sociality and discusses the theories of origin of sociality. The following chapters discuss the aspects of social insects in terms of antiquity and territoriality. Caste differentiation and division of labor is also emphasized, as well as the genetics of sociality. The last two chapters deal with the larvae of the social hymenoptera and the social and evolutionary significance of social insect symbionts. This volume is a good reference for students and teachers in the study of entomology, zoology, and biology.

  • Molecular Biology and Pathology

    A Guidebook for Quality Control
    • 1st Edition
    • Daniel H. Farkas
    • English
    This is the first handbook to provide an all-in-one guide to establishing molecular biology protocols with requisite quality control. Molecular Biology and Pathology will help professionals sift through the incredible wealth of information available on molecular biology, specifically as it relates to the clinical arena of molecular pathology. This handbook provides excellent training information, and the concern of safety is discussed extensively. The handbook can serve as a primer and reference for those interested in the technical topics described, including the brief discussion of DNA banking. Quality Control (QC) suggestions are also presented.

  • Recombinant DNA Methodology II

    • 1st Edition
    • Ray Wu
    • English
    The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

  • Viral Transformation and Endogenous Viruses

    • 1st Edition
    • Albert Kaplan
    • English
    Viral Transformation and Endogenous Viruses is a collection of papers presented at the symposium on ""Viral Transformation and Endogenous Viruses"" held at Vanderbilt University on April 1-2, 1974. Contributors discuss the viral function(s) responsible for the transformation of the cells that are infected with oncogenic viruses, emphasizing the type of changes that characterize transformed cells and the regulatory mechanisms that are altered after malignant transformations. This volume is organized into 10 chapters and begins with an overview of DNA-containing tumor viruses, particularly Simian Virus 40 (SV40) and its mutants with DNA deletions, insertions, and duplications. The integration and transcription of adenovirus DNA is considered, along with the characteristics of temperature-sensitiv... mutants of these viruses. The reader is then introduced to the chemistry and biology of RNA-containing tumor viruses, which are useful reagents to study neoplastic transformation both in vivo and in vitro. A major aspect of these viruses concerns the analysis of their genome at the chemical and genetic levels. The last part of the book is devoted to biochemical and genetic analyses of endogenous viruses isolated from avian cells. This book is a valuable resource for scientists and investigators in fields such as pathology, molecular virology, molecular biology, microbiology, oncology, and biochemistry.

  • Cellular and Molecular Neurobiology

    • 2nd Edition
    • Constance Hammond
    • English
    This Second Edition, is the new, thoroughly revised edition of the established and well-respected authoritative text in the field. Cellular and Molecular Neurobiology is hypothesis driven and firmly based on numerous experiments performed by experts in the field. Seven new chapters (five new and two totally rewritten) complement and expand on the first edition and are written in a way that encourages students to ask questions. Additionally, new, groundbreaking research data on dendritic processing is presented in a very easy-to-understand format.

  • Molecular Biology

    Elementary Processes of Nerve Conduction and Muscle Contraction
    • 1st Edition
    • David Nachmansohn
    • English
    Molecular Biology: Elementary Processes of Nerve Conduction and Muscle Contraction focuses on the underlying elementary processes of muscular contraction and nerve impulse conduction. This book explores the fundamental concepts and notions in molecular biology. Organized into 11 chapters, this book starts with an overview of the double array model of striated muscle. This text then discusses the structural changes at the molecular level, which occur as a consequence or an accompaniment of the chemical reactions that occur during contraction. Other chapters explain the process by which molecular changes are summated to produce macroscopic shortenings. This book discusses as well the molecular complementarity and chemistry of acetylcholinesterase... which provides significant information for the understanding of nervous activity. The final chapter deals with the structure of guanidinium ion, which consists of three equivalent NH2 groups arranged with a planar trigonal symmetry around the central carbon atom. Physicists, chemists, and biologists will find this book useful.

  • An Introduction to Animal Law

    • 1st Edition
    • Cooper
    • English
    Legislation relating to animals has ancient origins and in many civilizations certain species have held particular significance, be it religious, cultural, nutritional, or sporting. As a general rule, the law was primarily concerned with animals as property, rather than in need of protection, until the 19th century. Since the 1970s animal law has proved to be a growth area in the production and enforcement of both national and international legislation. This has been particularly so in the areas of conservation and welfare and there has been extensive legal and philosophical consideration of the status of animals.This book is not intended to be a standard text, but rather a handbook in the true sense, a guide for the lay person--namely, to help the non-lawyer to understand the basic concepts of animal law and to provide the lawyer (who is the lay person in the world of animal science) with an introduction to relevant concepts and literature which are not normally found in the conventional legal texts.

  • Isoenzymes In Biology and Medicine

    • 1st Edition
    • Albert Latner
    • English
    Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.

  • Transport And Diffusion Across Cell Membranes

    • 1st Edition
    • Wilfred Stein
    • English
    Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

  • Dimensions In Health Research: Search For The Medicines Of Tomorrow

    • 1st Edition
    • Herbert Weissbach
    • English
    Dimensions in Health Research: Search for the Medicines of Tomorrow is a collection of papers presented at the 1977 Symposium on Dimensions in Health Research: Search for the Medicines of Tomorrow, held in Basel, Switzerland, sponsored by the Roche Research Foundation for Scientific Exchange and Biomedical Collaboration. This symposium is organized in honor to Professor Alfred Pletscher, a known neurobiologist who led the discovery of drugs for the treatment of various central nervous disorders. This book is organized into three section encompassing 28 chapters. The first section covers the molecular biological aspects of gene expression; the biosynthesis of human interferon; the concept of DNA damage and repair; and the link between advances in molecular genetics and medicine. The second section discusses the pertinent advances in understanding the mechanism of immune system and its components. The third section surveys the trends in pharmacotherapy based on monoaminergic, adenosine triphosphate, gamma-amino butyric acid, amino acid, and peptide mechanisms. This book will prove useful to researchers in the fields of molecular biology, immunology, and neurobiology.

  • Development of Perception

    Psychobiological Perspectives
    • 1st Edition
    • Richard Aslin
    • English
    Development of Perception: Psychobiological Perspectives, Volume 2, The Visual System, is the second of two-part series covering vision, audition, olfaction, taste, tactile sensitivity, and sensory-motor activity during ontogenesis. The focus is on approaches to perceptual development that incorporate a psychobiological perspective. The present volume brings together several topics of critical importance to the process of understanding the visual system. The book is organized into three parts. Part A addresses the theoretical and interpretive issues involved in designing and drawing conclusions from research on the development of the visual system. Part B on animal studies of visual development covers the neural and behavioral characteristics of the cat and monkey visual system during the early postnatal period. Part C examines visual development in human infants. Together, these three parts offer a comprehensive coverage of major issues in the structure and function of the developing mammalian visual system. Each chapter emphasizes the behavioral consequences of developing visual functions.

  • Cellular Membranes in Development

    • 1st Edition
    • Michael Locke
    • English
    Cellular Membranes in Development covers the proceedings of the 1963 22nd Symposium on ""The Society for the Study of Development and Growth"" held in Storrs, Connecticut. This book is organized into 10 chapters that discuss the properties, isolation, function, composition, and physiological aspects of membranes. After briefly dealing with the principles of the unit membrane concept, the book describes the properties of lipid membranes of bilayer thickness with biological relevance. The next chapter focuses on hepatic cell and the modifications of the endoplasmic reticulum in cell differentiation in normal and cancerous growth. Another chapter describes the developmental changes in a particular experimental systems and the modification of the membranes by specific treatments using the apical portion of the primary root of Zea mays. The book also discusses the role of the different organelles in development, supporting the idea of topological continuity between the membranes of all the organelles except the mitochondria. Other chapters describe the cytology of oogenesis and fertilization in Pteridium aquilinum; the early events of fertilization in Hydroides and Saccoglossus; and the composition of cell walls of bacteria, yeast, and fungi. Some aspects of the capsules, microcapsules, and sheaths exhibited by some microorganisms are also covered. The last chapters deal with the quantitative aspects of plant cell permeation and permeability function and changes in relation to maturation and growth hormones. The book is an ideal source for cell biologists and researchers, evolutionists, and biochemists.

  • The Transfer of Calcium and Strontium Across Biological Membranes

    • 1st Edition
    • R Wasserman
    • English
    The Transfer of Calcium and Strontium Across Biological Membranes represents the proceedings of a Conference on The Transfer of Calcium and Strontium Across Biological Membranes, held in Cornell University, Ithaca, New York on May 13-16, 1962. This book is organized into seven sections encompassing 22 chapters, and deals first with some of the properties of biological membranes, the general aspects of ion transport, and chelation of divalent cations. These subjects are all important to understand the transfer of calcium and strontium across membranes. The subsequent sections are devoted to the physiological and nutritional aspects of intestinal absorption, with a particular emphasis on the influence of vitamin D and other nutritional factors on the absorption of calcium and strontium. A section describes the biological transfer and movement of calcium and strontium across kidney, mammary gland, nerve, and muscle. The last section examines the behavior of chronically ingested radiostrontium in animals. This section also provides an overview of strontium and calcium metabolism principles.

  • The Macrophage In Neoplasia

    • 1st Edition
    • Mary Fink
    • English
    The Macrophage in Neoplasia is a compilation of papers presented at a workshop held at the Marine Biological Laboratory, Woods Hole, Massachusetts, on October 8-11, 1975. The book presents the many faceted activities of macrophage. This book is divided according to the five sessions of the workshop. First session talks about the role of tumor macrophages in vivo. It then elucidates the macrophage function and indicates how the interaction of macrophages with other cells can alter the host-tumor balance. The remaining sessions, as presented in this book, explore the mechanism of macrophage mediated cytotoxicity, functional expression of macrophages and neoplasia, and the stimulation of macrophage function and applied therapy.

  • Bacillus Molecular Genetics and Biotechnology Applications

    • 1st Edition
    • A.T. Ganesan
    • English
    Bacillus Molecular Genetics and Biotechnology Applications contains the proceedings of the Third International Conference on the Genetics and Biotechnology of Bacilli, held at Stanford University in Stanford, California on July 15-17, 1985. Contributors discuss the progress that has been made concerning the molecular genetics and biotechnology of Bacillus and cover topics related to transposons and plasmids, secretion, gene cloning, and gene expression. This volume is organized into five sections encompassing 39 chapters and begins with an overview of the origin and the state of molecular genetics, along with some of the contributions microbiology has made to fundamental biology. It then emphasizes the importance of scientifically based regulatory decisions and responsible industry actions for effective biotechnology regulation. The chapters that follow focus on Bacillus subtilis, touching on topics such as DNA recombination in plasmids, genetic system for stabilizing cloned genes, regulation of sporulation, and non-complementing diploids. The reader is methodically introduced to the secretion and maturation of subtilisin, cloning in streptomycetes, and genetic exchange and prospects for cloning in Clostridia. The book concludes with a chapter that describes an integrative and amplifiable secretion vector using the inducible promoter and signal peptide from the B. subtilis levansucrase (LS) gene. This book will be of interest to geneticists, microbiologists, and biotechnologists, as well as students and researchers in the fields of molecular biology and biochemistry.

  • Crops as Enhancers of Nutrient Use

    • 1st Edition
    • R Duncan
    • English
    Crops as Enhancers of Nutrient Use examines the various plant and soil factors that contribute to nutrient use efficiency of plants. It attempts to address policies regarding Low Input Sustainable Agriculture (LISA), conservation-oriente... cropping systems, and reductions in environmental contaminants. It also presents longer-term remedies to some of the inherent problems of high volume applications of expensive fertilizer nutrients. This book emphasizes plant-soil interaction, particularly, nutritional interactions involving rhizosphere, microbes, and stress on the root system. Stress factors include moisture and low and high pH. The book also covers the genetic and physiological response of plant to nutrients at the cellular level, on a whole-plant basis, and when subjected to stress. This book will contribute to the development of a more cost-effective and judicious nutrient usage of major crops.

  • Plant Tissue Culture

    Techniques and Experiments
    • 1st Edition
    • Robert H. Smith
    • English
    Plant Tissue Culture Techniques and Experiments is a manual that contains laboratory exercises about the demonstration of the methods and different plant materials used in plant tissue culture. It provides an overview on the plant cell culture techniques and plant material options in selecting the explant source. This book starts by discussing the proper setup of a tissue culture laboratory and the selection of the culture medium. It then explains the determination of an explant which is the ultimate goal of the cell culture project. The explant is a piece of plant tissue that is used in tissue culture. Furthermore, the book discusses topics about callus induction, regeneration and morphogenesis process, and haploid plants from anther and pollen culture. The meristem culture for virus-free plants and in vitro propagation for commercial propagation of ornamentals are also explained in this manual. The book also provides topics and exercises on the protoplast isolation and fusion and agrobacterium-mediat... transformation of plants. This manual is intended for college students, both graduate and undergraduate, who study chemistry, plant anatomy, and plant physiology.

  • Ecology of Tropical Oceans

    • 1st Edition
    • Bozzano G Luisa
    • English
    This book breaks new ground with the integration of geography, oceanography, plankton and benthic biology, as well as fish, to present a comprehensive account of the ecology of the tropical ocean. Proceeding from a description of the geomorphology, sediments, and vegetation of tropical continental shelves and the oceanography of tropical regions, the authors describe the benthos, plankton, and fish communities of tropical seas. An examination of the production of plant and animal life in tropical oceans is presented together with the numerical population biology of fish and invertebrates.

  • Optical Techniques in Biological Research

    • 1st Edition
    • Denis Rousseau
    • English
    Optical Techniques in Biological Research discusses the fundamentals and applications of light scattering, Raman scattering, Fourier transform infrared spectroscopy, nanosecond fluorescence spectroscopy, and circular dichroism. Electron microscopy is also included owing to some of its classical similarity to optical microscopy optical structural and resonance techniques for biological research. The chapters are aimed at a level such that only a general understanding of chemistry and biology is required. The objective is to present material in a way that allows the research worker to assess quickly the applicability, utility, and significance of the specific technique to his or her problem or field of interest. Together with Structural and Resonance Techniques in Biological Research, this book marks the introduction of a new series of volumes, Physical Techniques in Biology and Medicine, which is intended to replace a previous treatise, Physical Techniques in Biological Research.

  • Tropical Diseases of Legumes

    • 1st Edition
    • Julio Bird
    • English
    Tropical Diseases of Legumes consists of papers presented at a workshop held at Rio Piedras Agricultural Station, University of Puerto Rico, in June 1974. Legumes are group of plants that provide an important and often sole source of protein in the diet of millions of people. In the growing problem of hunger, there is an immediate need to raise the production of legumes through better knowledge of plant diseases, by ultimate prevention of these diseases, and through improved crop production. Consequently, a workshop is organized and the presented papers, grouped into four parts, are shown in this book. The first two parts describe the rugaceous and mosaic diseases. Bacterial diseases, chemical control, and ecology of pathogens are explained in the third part of this book. The last part explores the origin and improvement of the common bean, as well as its diseases in the tropical Americas. This book aims to provide a stimulating forum for discussion of the findings and observations in tropical legume disease research.

  • Psychopharmacological Agents V4

    • 1st Edition
    • Maxwell Gordon
    • English
    Psychopharmacologica... Agents, Volume IV summarizes the chemistry, pharmacology, and clinical manifestations of psychoactive drugs which are abused, with emphasis on opiate abuse and its treatment. The historical, legal, regulatory, and sociological aspects of the abuse of central nervous system agents are described, along with the treatment modalities that have evolved from some of these afflictions. Comprised of six chapters, this volume begins with an introduction to drug abuse and drug dependence, followed by a discussion on various perspectives in drug abuse and modalities for treating patients who are dependent on opiates. Studies on non-abusive analgetics such as opium compounds are then reviewed, together with the chemistry, mechanism of action, and medical applications of psychotomimetic drugs. The final two chapters deal with the treatment of opiate abuse by methadone maintenance and the regulatory aspects of drug abuse. This book will be of interest to students, practitioners, and researchers in medicinal chemistry, psychology, and pharmacology.

  • Reproduction of Marine Invertebrates V4

    Molluscs: Gastropods and Cephalopods
    • 1st Edition
    • Arthur Giese
    • English
    Reproduction of Marine Invetebrates, Volume IV Molluscs: Gastropods and Cephalopods describes the wide range of structural complexity and diverse modes of reproduction of gastropods and cephalopods. Each chapter discusses the asexual reproduction, sexual reproduction capacity, and developmental stages of different group of gastropods and cephalopods, including prosobranchia, opisthobranchia, pulmonata, nautiloidea, decapoda, and octopoda. Gastropods are among the most conspicuous sea animals, and species of limpets, snails, and slugs are found in all marine habitats. Cephalopods are active and important marine predators, ranging from archaic nautiloids to more recent pelagic decapods and benthic octopods, which are often considered to be one of the apexes of invertebrate evolution. They are all gonochoric and reproduce only by sexual means. All have intricate courtship behavior and derived developmental patterns. Marine biologists and researchers, scientists, and developmental biologists will find this book invaluable.

  • Agricultural Engineering Soil Mechanics

    • 1st Edition
    • Volume 10
    • E. McKyes
    • English
    This book provides an introduction to classical soil mechanics and foundation engineering, and applies these principles to agricultural engineering situations. Theoretical design formulae are given, plus tables and graphs dealing with bearing capacity factors, wall pressure factors, soil cutting numbers and soil mechanical properties. Many example problems of design and analysis are solved in the text, and there are unsolved problems given for each chapter.The text begins with descriptions of soil origins and classification systems, including agricultural classification schemes, and then introduces classical concepts of soil strength and strength measurement techniques in the laboratory and in the field. Soil mechanics is applied to the design of shallow foundations, and the design formulae as well as tables of bearing capacity factors for design use are provided. New research and design findings in the specialized area of tall and heavy farm silos are also given, in addition to deep pile foundation design for heavy structures on very soft soils. Water flow in soils is treated, together with stability of ditch bank slopes and small earth dams, design of retaining walls and pressure pressures in bins and silos, soil erosion and protection methods, soil cutting and tillage design methods, soil compaction analysis, the use of geotextiles and problems of soil freezing.The book is directed primarily at professional university students in Agricultural Engineering, but will also be of interest to scientists working in other engineering branches, landscape architecture, soil physics and the like.

  • Newer Methods of Nutritional Biochemistry V3

    With applications and interpretations
    • 1st Edition
    • Anthony Albanese
    • English
    Newer Methods of Nutritional Biochemistry: With Applications and Interpretations, Volume III presents the pressing problems in emergency feeding of populations in developing areas of the world with emphasis on the need for simple procedures to assess utilization of dietary proteins. This book reviews the criterion of protein utilization and considers the important components of protein metabolism. Organized into 11 chapters, this volume starts with an overview of the metabolic changes induced by deficiencies of essential nutrients. This text then examines the problems of human protein needs in the light of the food habits of vegetarians. Other chapters explore lipid metabolism in terms of its dynamic mechanisms. This book discusses as well the significance of minerals in the utilization of primary foodstuffs, namely, carbohydrates, proteins, and fats. The final chapter deals with the methodology for studies in human nutrition. This book is a valuable resource for biochemists, graduate students, and clinical researchers.

  • Comparative Anatomy And Development

    • 1st Edition
    • Geoffrey Bourne
    • English
    Hearts and Heart-Like Organs, Volume 1: Comparative Anatomy and Development focuses on the complexities of the heart and heart-like organs in various species, from the invertebrates and the lower vertebrates to humans. More specifically, it investigates the hearts of worms and mollusks, urochordates and cephalochordates, fishes, amphibians, reptiles, birds, mammals, and humans. Organized into 11 chapters, this volume begins with an overview of myogenic hearts and their origin, the circulatory system of the annelids, and the nervous control and pharmacology of mollusk hearts. It then discusses the phyletic relationships and circulation systems of primitive chordates, cardiovascular function in the lower vertebrates, fine structure of the heart and heart-like organs in cyclostomes, and fine structure as well as impulse propagation and ultrastructure of lymph hearts in amphibians and reptiles. It also explains the neural control of the avian heart, functional and nonfunctional determinants of mammalian cardiac anatomy, postnatal development of the heart, and anatomy of the mammalian heart. The book concludes with a chapter on the anatomy of the human pericardium and heart. This book is a valuable resource for biological and biomedical researchers concerned with the anatomy and physiology of the heart.

  • Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins

    • 1st Edition
    • Gebhard Koch
    • English
    Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins presents the proceedings of the international conference held in Hamburg-Blankenese on May 27-31, 1980. The book discusses topics on polyproteins, polyfunctional proteins, precursor proteins, as well as the differences in synthesis and processing of ACTH/endorphin peptides in primary cultures of anterior and intermediate lobes of the pituitary. The text also presents evidence for a self-cleaving precursor of virus-coded protease, RNA-replicase, and VPg; and the role of Pr180gag-pol in the characterization and genetic analysis of retrovirus maturation.

  • Organic Photochemistry

    Principles and Applications
    • 1st Edition
    • Jacques Kagan
    • English
    Organic Photochemistry outlines the principles, techniques and well-known reactions occurring in organic molecules and also illustrates more complex photochemical transformations occurring in organic chemistry. Many photochemical transformations convert simple molecules into extremely complex products with an ease not approached by the standard synthetic chemistry practiced in the laboratory. In the earlier chapters, the author outlines the principles, techniques and some of the well-known reactions occurring in organic molecules and later illustrates more complex photochemical transformations occuring in organic chemistry. Experimental techniques are included to encourage novices. Topics are emphasized where structural transformations can be formulated chemically. Practical applications are collected together. The book starts at a comfortably simple level with enough examples to provide an introduction to the diversity of photochemical reactions.

  • Glutathione Centennial

    Molecular Perspectives and Clinical Implications
    • 1st Edition
    • Naoyuki Taniguchi
    • English
    Glutathione Centennial: Molecular Perspectives and Clinical Implications is a collection of papers presented at the international symposium by the same titles, held in Osaka, Japan on December 1-4, 1988. This symposium concentrates on the developments is glutathione field, especially those related to molecular and clinical problems. This book is organized into five parts encompassing 30 chapters. Part I deals with the metabolic regulation, thermodynamic and kinetic properties, and enzyme regulation of glutathione. Part II examines the gene expression and molecular mechanism of glutathione-related enzymes, while Part III explores the association between carcinogenesis, xenobiotic compounds, and glutathione. Part IV highlights the clinical implications of glutathione, particularly its effect on vasospasm in subarachnoid hemorrhage and experimental hepatitis. Part V discusses the mechanism and regulation of biological transport of glutathione. This book will be of great value to glutathione enthusiasts and to many scientists in the brad fields of biology and medicine, and to their students.

  • Pathology of Domestic Animals

    • 4th Edition
    • English
    The all-new Fourth Edition of Pathology of Domestic Animals comprehensively covers the biology and pathology of diseases of domestic animals on a systemic basic. Updated and expanded to reflect the current knowledge of the study of domestic animal diseases, this three-volume set appeals to veterinarians, veterinary students, trainee veterinary pathologists learning the scope of their field, and practicing pathologists confronted with diagnostic problems.

  • Handbook of Mutagenicity Test Procedures

    • 2nd Edition
    • B.J. Kilbey + 3 more
    • English
    The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.

  • The Glycoconjugates V4

    Glycoproteins, Glycolipids and Proteoglycans
    • 1st Edition
    • Martin Horowitz
    • English
    The Glycoconjugates: Mammalian Glycoproteins, Glycolipids, and Proteoglycans Volume IV is a collaboration of different experts in the field of molecular biology on the subject of glycoconjugates. The fourth volume covers topics such as the uptake of glycoconjugates and transport of lysozomal enzymes, and the hepatic receptor for asialoglycoproteins. Also covered in this volume are topics such as the use of neoglycoproteins as probes for binding and cellular uptake of glycoconjugates; the transfer of glycoconjugates from living to fixed cells; and the biosynthesis, function, and host interaction of virus glycolipids and glycoproteins. The book is recommended for molecular biologists, organic chemists, and biochemists who would like to know more about glycolipids and glycoproteins and their applications.

  • The Biology of the Monotremes

    • 1st Edition
    • Mervyn Griffiths
    • English
    The Biology of the Monotremes is an attempt to make available all gathered information about monotremes to the greater public. This book specifically targets the students, newly graduates, teachers, and researchers interested in the study of life processes and evolution. This book comprises of 10 chapters. Each chapter except Chapter 10 discusses three genera - Ornithorhynchus, Tachyglossus, and Zaglossus. Chapter 1 serves as an introduction to the subject matter. It covers the discovery and general anatomy of the monotremes. In accordance, Chapter 2 discusses the different kinds of monotremes and its other aspects. Aside from the mentioned genera, it also includes Obdurodon insignis. In Chapter 3, the food and feeding habits of the monotremes is given focus. Meanwhile, the varied physiology of monotremes is the subject of Chapter 4, and temperature regulation in Chapter 5. A more detailed and thorough discussion regarding the anatomy of the monotremes is provided in Chapters 6 through 9. The discussion covers topics including the glands in the endocrine and immune systems, as well as special senses, organs, and behavior of monotremes. Its reproduction and embryology is also discussed. This book explains as well the mammal’s lactation, composition of the milk, sucking, and growth of the young. Lastly, Chapter 10 provides the readers with four differing views regarding the relationship of the monotremes with the rest of the mammals.

  • Physiology of the Amphibia Volume 2

    • 1st Edition
    • Lofts
    • English
    Physiology of the Amphibia, Volume II focuses on the various aspects of amphibian reproduction, both physiological and behavioral, and the interrelationship between these mechanisms and the environment. Organized into five chapters, the book begins with the integrative functions of the amphibian brain. It then describes the cytophysiology of the amphibian adenohypophysis, as well as their reproductive organs and associated sexual structures. It also discusses the physiology of the process of yolk formation, vitellogenesis. The reproductive and courtship patterns and intersexuality among amphibians are also described. This book will be useful to general biologists as a reference source and to students with interests in animal physiology.

  • Plant Nonprotein Amino and Imino Acids

    Biological, Biochemical, and Toxicological Properties
    • 1st Edition
    • Gerald Rosenthal
    • English
    Plant Nonprotein Amino and Imino Acids: Biological, Biochemical, and Toxicological Properties provides a comprehensive discussion of plant nonprotein amino acids. Much of this monograph is written with the neophyte in mind, thus necessitating the presentation of certain basic concepts that are well-known to the advanced worker. Rather than providing an exhaustive coverage of the subject matter, the book attempts to represent effectively the state of the art; to provide a helpful means of identifying and locating the pertinent literature; and to present the basic information necessary to encourage other workers to enter into the study of the nonprotein amino acids. The book begins with a review of nomenclature and physicochemical properties. This is followed by a discussion of analytical methods such as partition paper chromatography, thin-layer chromatography, ninhydrin color reaction, ion-exchange chromatography, and gas chromatography. Subsequent chapters deal with the toxicity of some nonprotein amino acids and their ability to exert debilitating effects in a host of organisms; and the intermediary metabolism of nonprotein amino acids.

  • Feeding Behavior

    Neural and Humoral Controls
    • 1st Edition
    • Robert Ritter
    • English
    Feeding Behavior: Neural and Humoral Controls discusses the role of well-known neural or humoral substrates. This book describes the neural and humoral mechanisms whose participation in the control of feeding is understudied. Organized into 11 chapters, this book starts with an overview of the ingestive behaviors of altricial mammals that mature through three transformations. This text then proceeds with a discussion of the separateness of the suckling and adult ingestion in laboratory rat pups, which revealed the existence of a system for ingestive behavior that is different from suckling. Other chapters discuss the physiological research on the feeding behavior, which is centered on the hypothalamus. This book examines as well the major brain region that is involved in the control of food intake. The final chapter examines the role of central cholecystokinin in the satiating effect of ingested food. Veterinary scientists and researchers will find this book extremely useful.

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