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Elsevier

Books in Life sciences

  • Spontaneous Animal Models of Human Disease

    • 1st Edition
    • Volume 2
    • Edwin J. Andrews + 2 more
    • English
    This two-volume work gathers together the diverse information presently available on spontaneous animal models of human disease. In addition to providing a comprehensive review of existing models, the book presents many previous unpublished new models.The scope of this work is limited to spontaneous models. Neoplasia, infectious diseases including parasitism, and nutritionally induced or other types of experimental models have not been included. The sixteen parts of the book are alphabetically arranged according to organ system with over 230 authors contributing to the overall effort. In addition to many illustrations, the book features an extensive bibliography.

  • Physiological Correlates of Emotion

    • 1st Edition
    • Perry Black
    • English
    Physiological Correlates of Emotion focuses on the major experimental approaches currently applied to the study of emotion and its physiological or behavioral parameters. It explores the heritability and developmental aspects of emotional behavior as well as its neurochemical and endocrine, neurophysiological, and psychophysiological correlates. In particular, it considers the modification of emotional behavior by intracranial administration of chemicals, the link between the limbic brain and psychoses, the role of nonspecific reticulo-thalamo-cor... systems in emotion, modulation of emotion by cerebral radio stimulation, and the role of brain function in emotion. Organized into five sections comprised of 13 chapters, this book begins with a historical overview of research in emotion and behavior theory. It then discusses the studies dealing with heritability of emotional behavior in animals. The remaining chapters tackle the maturation of social-emotional patterns, localization of biogenic amines in the brain, psychophysiological experiments on the endocrine and autonomic correlates of emotional behavior, and psychotic manifestations of limbic dysfunction in humans. It explains the two-way radio communication with the human brain, the behavioral significance of bradycardia and hypotension, the perception and labeling of bodily changes as determinants of emotional behavior, and the conditioned emotional states. The book concludes with a phenomenological analysis of brain function in emotion. This book is essential reading for psychologists, psychiatrists, physiologists, and those working in the medical and behavioral sciences.

  • Stem Cells of Renewing Cell Population

    • 1st Edition
    • A.B. Cairnie
    • English
    Stem Cells of Renewing Cell Populations constitutes the proceedings of the ""Stem Cells in Various Tissues"" symposium, organized as a tribute to Charles P. Leblond on the occasion of his 65th birthday. The pioneering studies of Dr. Leblond on the kinetics of cell populations led him to the identification and analysis of the behavior of the ""stem cells,"" which are at the origin of each cell line. This book focuses on the study of stem cells in various organs, including intestine, epidermis, hematopoietic and lymphoid tissues, and testis, under normal steady state conditions. It examines the behavior of stem cell in these organs, such as cell cycle and differentiation and regulation using several distinct techniques. The concluding part discusses the behavior of hematopoietic stem cell during growth and aging, as well as its distribution and dynamics in tumor-bearing tissues. Workers from many disciplines, including biologists, stem cell biologists, and regenerative medicine researchers will greatly benefit from this book.

  • Basic Mechanisms in Hearing

    • 1st Edition
    • Aage Moller
    • English
    Basic Mechanisms in Hearing is a collection of papers that discusses the function of the auditory system covering its ultrastructure, physiology, and the mechanism's connection with experimental psychology. Papers review the mechanics, morphology, and physiology of the cochlear, including the physiology of individual hair cells and their synapses. One paper examines the combined physiological and anatomical studies of stimulus coding in the mammalian auditory nervous system. The results of these studies pertain to the latency, frequency selectivity, and time pattern of responses to short tone bursts. Other research compare the cochlear nerve, behavioral, and psychophysical frequency selectivity which show that frequency selectivity of the auditory system occurs at the level of the cochlear nerve, becoming downgraded in end-organ deafness. Other papers discuss neural coding at higher levels such as the feature extraction in the auditory system of bats. Some papers also analyze the specialized hearing mechanisms in animals, for example, the echolocation of bats and in some insects, the function of the swimbladder in fish hearing, as well as the "invertebrate frequency analyzer" in the locust ear. Physiologists, neurophysiologists, neurobiologists, general medical practioners, and EENT specialists will find this collection valuable.

  • Cytogenetics, Host–Parasite Interactions, and Physiology

    • 1st Edition
    • B Zuckerman
    • English
    Plant Parasitic Nematodes, Volume II: Cytogenetics, Host-Parasite Interactions, and Physiology is a masterful reference work in nematology that includes information in ultrastructure, enzymology, and chemistry of body composition; culturing; virus transmission; biological races; and nature of plant resistance. This volume provides information about plant parasitic nematode genetics and cytology. It first explains the history and the advances in nematology, and then discusses the more specific topics about the biological processes involving nematodes. The discussions on host-parasite interactions, biochemistry, and physiology follow these topics. This book also presents useful information regarding free-living and animal parasitic nematodes. This treatise is written to provide an up-to-date reference source for students, lecturers, and research professionals in plant parasitology, specifically nematology, and related fields.

  • Introduction to Modern Biochemistry 4e

    • 4th Edition
    • P Karlson
    • English
    Introduction to Modern Biochemistry, Fourth Edition provides an understanding of the chemical background of biological phenomena. This book discusses the concepts of generation and utilization of free energy. Organized into 23 chapters, this edition starts with an overview of the important role of amides in biochemistry. This text then explores the chemical structure of proteins and describes the methods of determining the amino acids sequence of proteins. Other chapters consider the role of genes in protein and enzyme synthesis. This book discusses as well the significance of the submicroscopic structure of the cell in biochemical reactions. The reader is also introduced to the chemistry of the carbohydrates. The final chapter deals with biochemical functions of various organs, including the digestive tract, liver, kidney, nervous system, muscles, and connective tissues. This book is a valuable resource for biologists, biochemists, scientists, researchers, and readers who are interested in the field of biochemistry.

  • Natural Cell-Mediated Immunity Against Tumors

    • 1st Edition
    • Ronald Herberman
    • English
    Natural Cell-Mediated Immunity Against Tumors aims to be the first book to provide a comprehensive discussion on natural cell-mediated immunity against tumors. This book is mostly a collection of different research contributed by leading laboratories. It also presents a better perspective of how natural mechanisms fit in with and relate to the traditional and more extensively studied components of the immune system. The book starts off with an overview of the contents of the volume – the historical development of the advances in the field of research and the status of knowledge in the subject area. Divided into four major sections, the book consists of a total of 98 chapters. The sections discuss the natural killer cells and related cells and the natural lymphokine production. This book also explains the natural macrophage and granulocyte cytotoxicity. The book will be a helpful reference for students, professionals, and researchers in biology, immunology, biochemistry, microbiology, and other related fields.

  • Signal Transduction During Biomembrane Fusion

    • 1st Edition
    • Danton H. O'Day
    • English
    Signal Transduction during Biomembrane Fusion begins with three review articles that put the problem of signal transduction and biomembrane fusion into a general perspective. Each subsequent chapter begins with an introduction which reviews past work on a specific biological system. The authors' current research is then detailed. The chapters conclude with final comments wherein the contributors express viewpoints about the general significance and progression of their work. This book comprises 12 chapters, with the first focusing on signal transduction during biomembrane fusion. The succeeding chapters then discuss the ""focal membrane fusion"" model; osmotic phenomena in membrane fusion; cell signaling and regulation of exocytosis at fertilization of the egg; and signal transduction during exocytosis in mast cells. Other chapters cover protein kinase c and granule membrane fusion; GTP-binding proteins and formation of secretory vesicles; and signal transduction during phagocytosis. The remaining chapters discuss calcium signal transduction pathway and myoblast fusion; phospholipid metabolism during calcium-regulated myoblast fusion; protein kinase c, membrane protein phosphorylation, and calcium influx in chick embryo skeletal myoblast fusion; and signal transduction and cell fusion in dictyostelium. This book will be of interest to practitioners in the fields of neurobiology, zoology, and the biological sciences.

  • Neurotransmitters And Anterior Pituitary Function

    • 1st Edition
    • Giuseppe Nistico + 1 more
    • Eugenio Muller
    • English
    Neurotransmitters and Anterior Pituitary Function discusses research findings on neurotransmitter-neu... interactions in the control of the anterior pituitary. This book contains five chapters that specifically tackle the most salient constituents of the neural-endocrine communication system in mammals. This book deals first with the biochemistry, physiology, and pharmacology of proved or putative neurotransmitters, as well as some of the techniques used for determining their synthesis or turnover in the central nervous system (CNS) of experimental animals or in man. These topics are followed by a discussion on the principal functions of the most well-known neurotransmitter containing neurons based on sophisticated techniques for neurotransmitter measurements. A chapter highlights both traditional and a vast series of developed drugs that affect both neurotransmitter and neuroendocrine function. Discussions then shift to the experimental evidence on pituitary function control by the brain through releasing and inhibiting hormones secreted by hypothalamic neuroendocrine cells; the chemical isolation, identification, and synthesis of hypothalamic neurohormones; and concepts of their mechanism of action at the level of the pituitary cells. This text further explores the role of specific brain neurotransmitters in controlling pituitary hormone secretions in both experimental animals and in man and the possible CNS site(s) where neurotransmitters and neurohormones interact for the control of anterior pituitary secretion. The concluding chapter describes the actual or potential application of neuropharmacologic approaches to the diagnosis of and therapy for specific disorders of neuroendocrine function. Clinical neuroendocrinologist... and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.

  • Mineral Nitrogen In The Plant-Soil System

    • 1st Edition
    • R Haynes
    • English
    Mineral Nitrogen in the Plant-Soil System provides integrated accounts of the transformations and fate of mineral nitrogen in the plant-soil system. This book emphasizes the understanding of various processes and the factors that affect these processes. It also focuses on the role of biological nitrogen fixation in nitrogen cycling in natural and agricultural systems. The book is divided into seven major chapters and each chapter is further subdivided into various subtopics. The first chapter introduces and outlines the origin, distribution, and cycling of nitrogen in natural and agricultural terrestrial ecosystems. Chapter 2 focuses on the processes of decomposition and mineralization-immob... turnover. The processes of nitrification are discussed in detail in Chapter 3. The following four chapters discuss topics of retention and movement of nitrogen in soils; gaseous losses of nitrogen; uptake and assimilation of mineral nitrogen by plants; and lastly, the use of nitrogen in agronomic practice. The book will be invaluable to graduate students and researchers in the field of agriculture. This will also cater other parties interested, such as agronomists, soil scientists, plant physiologists, horticulturists, and foresters.

  • Wood Microbiology

    Decay and Its Prevention
    • 1st Edition
    • Robert A. Zabel + 1 more
    • English
    An in-depth examination of deterioration caused by fungi and other microorganisms, Wood Microbiology explores the major damages to wood and wood products during growth, harvesting, storage, and conversion to finished lumber. The characteristics, causes, detection, effects, and control measures for wood damage are stressed.

  • Cell, Tissue, and Organ Cultures in Neurobiology

    • 1st Edition
    • S. Fedoroff
    • English
    Cell, Tissue, and Organ Cultures in Neurobiology emerged from an international workshop held at the University of Saskatchewan in March 1977. This book reviews the uses of cell, tissue, and organ cultures in neurobiological research. It brings together an interdisciplinary perspective from morphology, biochemistry, pharmacology, endocrinology, embryology, and genetics. The book is organized into seven parts. Part I contains papers on the characteristics of differentiated cells. Part II presents studies on cell differentiation in primary cultures. Part III deals with studies on cell cultures and cell strains. Part IV focuses on phenotypic cell expression. Part V examines various cellular interactions. Part VI covers studies on nutrition while Part VII takes up applications of cell tissue and organ cultures in neurobiology. The book is directed toward tissue culturists concerned with the nervous system, as well as all neurobiologists, cell biologists, and embryologists interested in learning how neural cells and tissues behave in cultures and what has been learned about the nervous system using tissue culture methods, including the applicability of tissue cultures to the study of cell differentiation.

  • Protein Phosphorylation in Control Mechanisms

    • 1st Edition
    • F Huijing
    • English
    Protein Phosphorylation in Control Mechanisms contains the proceedings of the Miami Winter Symposia entitled ""Protein Phosphorylation in Control Mechanisms,"" held on January 15-16, 1973, in Miami, Florida, and organized by the Department of Biochemistry at the University of Miami School of Medicine. The papers explore the role of protein phosphorylation in control mechanisms, including muscle metabolism and function, cell division, and histone and protamine binding to DNA. This volume is comprised of 28 chapters and begins with an overview of Earl W. Sutherland's scientific work and the involvement of cyclic AMP in enzyme inductions. The discussion then turns to the regulation of muscle metabolism and function by protein phosphorylation; the link between hormonally regulated enzymes in adipose tissue and cyclic AMP-dependent protein kinase; and regulation of the mammalian pyruvate dehydrogenase complex by phosphorylation and dephosphorylation. Subsequent chapters focus on the role of histone phosphorylation in cell division; histone phosphorylation and regulation of nuclear function; and protein phosphorylation in retinal photoreceptors. The final chapter is devoted to acetylation of nuclear proteins in rat testis. This book should be a valuable resource for biochemists.

  • Lung Development Biological and Clinical Perspectives

    Biochemistry and Physiology
    • 1st Edition
    • Philip Farrell
    • English
    Lung Development: Biological and Clinical Perspectives: Biochemistry and Physiology, Volume I, provides a comprehensive and multidisciplinary treatise with regard to surfactant-related issues in lung maturation. Despite the deliberate emphasis on biochemistry in this volume, the aim is to place this information in the perspective of anatomy, physiology, and clinical perinatology. The book is organized into four parts. Part I offers a brief historical perspective by reviewing the chronology of clinical and basic advances. Part II then establishes a frame of scientific reference by reviewing the morphology and cytology of lung development and the physiology of pulmonary surfactant. Stages of development and variations in the maturation process are emphasized, while cautions to the biochemist are offered with respect to interpretation of experimental data. Part III provides an introduction to lung biochemistry. Part IV deals with the developmental biochemistry of lung phospholipid metabolism; the featured compound is the predominant surfactant component, phosphatidylcholine (PC). A focal point for discussion concerns regulatory mechanisms operating to control the production of saturated PC during late gestational development of the fetal lung.

  • Current Topics in Biochemistry

    • 1st Edition
    • C.B. Anfinsen
    • English
    National Institutes of Health Lectures in Biomedical Sciences: Current Topics in Biochemistry is based on a series of lectures dealing with current topics in biochemistry and more biologically or medically oriented topics. These lectures were organized for the benefit of young physicians who had just finished their clinical training but were several years out-of-date with respect to basic scientific research. The lecturers were asked, therefore, to present not only their own contributions to the field but also a broad review of recent developments in a large area of science. The lectures were surprisingly well attended not only by the associates for whom they had originally been designed but also by a large fraction of the NIH research community, specialists and nonspecialists alike. The lectures in this volume cover the following topics: genetic control of lipid metabolism; mammalian RNA-containing tumor viruses; current directions in research on cyclic AMP; the chemistry and biology of collagen; properties of the protein complex of striated muscle involved in the contractile process; cell surface receptor sites; and membrane structure and function.

  • The Carbohydrates

    Chemistry And Biochemistry Physiology
    • 1st Edition
    • Ward Pigman
    • English
    The Carbohydrates: Chemistry, Biochemistry, Physiology is a 15-chapter text that covers the significant developments in the biochemical and physiological aspects of the carbohydrates. The first two chapters explore the structure, stereochemistry, occurrence, properties, and synthesis of monosaccharides. Considerable chapters are devoted to the chemical aspects of various classes of carbohydrates, including esters, glycosides, acetals, polyols, acidic carbohydrates, ethers, nitrogenous derivatives, oligosaccharides, polysaccharides, and glycosidases. The discussion then shifts to the qualitative and quantitative determination of carbohydrates, as well as their photosynthesis and metabolism. The final chapters focus on the important role of carbohydrates in nutrition and in dental aspects. This work will be of value to chemists, biochemists, industrialists, biologists, histochemists, students, and medical and dental research workers.

  • The Bone and Mineral Manual

    A Practical Guide
    • 1st Edition
    • Michael Kleerekoper + 2 more
    • English
    The Bone and Mineral Manual incorporates the most up-to-date laboratory methods, techniques, and approaches for designing strategies and investigating the pathophysiology of bone and mineral metabolism. It presents information in a succinct format that allows practitioners to find the answers they need quickly and easily--even while the patient encouter is still in progress. This practical guide will become a frequent companion of endocriniologists, bone and mineral specialists, and nephrologists.

  • Cell Physiology Source Book

    Essentials of Membrane Biophysics
    • 3rd Edition
    • Nicholas Sperelakis
    • English
    This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death.

  • Transgenic Animal Technology

    A Laboratory Handbook
    • 1st Edition
    • Carl A. Pinkert
    • English
    Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions, as well as to make practical applications to production agriculture. This well-illustrated handbook covers the technical aspects of gene transfer in animals--from molecular methods to whole animal considerations--for the important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students.

  • Recombinant DNA Methodology II

    • 1st Edition
    • Ray Wu
    • English
    The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

  • Neuronal and Glial Proteins

    Structure, Function, and Clinical Application
    • 1st Edition
    • Paul Marangos
    • English
    Neuronal and Glial Proteins: Structure, Function, and Clinical Application focuses on the basic and clinical information relating to a number of proteins that are either enriched in or unique to nervous tissue. This book discusses the structural and functional characteristics of cell-specific proteins, which provide a better understanding of the molecular mechanisms involved in processes that are specific to glia or neurons. Organized into three sections encompassing 15 chapters, this book starts with an overview of the fundamental principles and strategies involved in studying the anatomical, structural, functional, and immunological aspects of brain protein. This text then discusses the techniques, including the preparation of brain tissues as well as the preparation of neural and glial cells in purified form. Other chapters review the two-dimensional gel electrophoresis, which is recognized as a significant technique for discovering brain molecules. The final chapter deals with the membrane-associated nervous system proteins. Neurochemists and clinical researchers will find this book useful.

  • Pertussis Toxin

    • 1st Edition
    • Ronald Sekura
    • English
    Pertussis Toxin presents the proceeding of the Pertussis Toxin Conference, held in Bethesda, Maryland, on September 20–21, 1984. This book discusses the perspective of the pertussis toxin and the potential role of the toxin in the development of new acellular pertussis vaccines. Organized into 13 chapters, this text begins with an overview of the biological activities of pertussis vaccine, which enhanced the production of antibodies to antigens. This book then examines the interesting action of pertussis vaccine to stimulate antibody production, particularly as an effective adjuvant for the production of IgE isotype of antibodies. Other chapters consider the experimental approaches used in the study of the mechanisms by which hormones produce their physiological effect. The final chapter examines the several features of the Bordetella adenylate cyclase toxin, which suggest that the molecule may follow the A/B model proposed for a number of bacterial toxins. This book is a valuable resource for toxicologists, immunologists, bacteriologists, and pharmacologists.

  • Spermiogenesis

    • 1st Edition
    • David Phillips
    • English
    Spermiogenesis summarizes the process of sperm structure and development in a variety of organisms. It attempts to illustrate the structure of the organelles that characterize mature spermatozoa and to trace the morphogenesis of these organelles during sperm formation. This task is complicated by considerable variations in the structure of spermatozoa among different species and the lack of good morphological studies of sperm structure and spermiogenesis in many animal groups. The general morphological features of mammalian sperm structure differ in some ways from the features of insect sperm, the spermatozoa produced by insects appearing relatively more simple. When the functions and developmental regions of the organelles are considered, homologies between complex structures found in mammalian sperm and simpler insect sperm structures may be deduced even though the organelles in question are quite dissimilar in appearance. Such homologies will be stressed in an effort to present as general a picture of spermiogenesis as seems consistent with the species-specific variations that exist. This book will be a useful, stimulating reference for students of reproductive biology.

  • The Structure and Function of Nervous Tissue V2

    Structure I
    • 1st Edition
    • Geoffrey Bourne
    • English
    The Structure and Function of Nervous Tissue, Volume IV: Physiology II and Biochemistry II focuses on the structure and function of nervous tissue. It investigates the plasticity of synapses, their degeneration and regeneration, neuronal inclusions, RNA of nervous tissue, and molecular organization of neural information processing. Furthermore, it covers topics on gamma-aminobutyric acid (GABA) in the nervous system, the blood-brain barrier, and the extracellular space (ECS) in the vertebrate central nervous system (CNS). Organized into 10 chapters, this volume begins with an overview of synapses, with emphasis on changes in both the efficacy of individual synapses and the numbers of synapses made by axons upon neurons. It then discusses the orthograde terminal degeneration of synapses and the use of light and electron microscopy in studying synapse degeneration and regeneration. It also explains the synthesis, storage, and release of acetylcholine from nerve terminals; inclusions associated with viral infections; metabolism of RNA in nervous tissue; chemical correlates of information processing; metabolism of GABA in mammalian CNS; electrical activity of the normal brain; and chemistry of the cerebrospinal fluid. The book concludes with a chapter on the mechanism by which vertebrate central nervous tissue alters the magnitude of the ECS. This book will be of interest to anatomists, embryologists, biochemists, pathologists, clinicians, and molecular biologists. This will be invaluable as well to graduate students in a variety of disciplines and those specializing in particular aspects of nervous tissue study.

  • The Developmental Biology of Reproduction

    • 1st Edition
    • Clement Markert
    • English
    The Developmental Biology of Reproduction documents the proceedings of the 33rd symposium of the Society for Developmental Biology. Reproductive Biology was selected as the main theme of the symposium. The symposium aimed to draw center attention on basic aspects of reproduction in both plants and animals in the hope of stimulating research that might provide the necessary foundation for effective, practical control of human reproduction. Five areas were selected for emphasis: the formation of eggs and sperm; the activation of the egg to develop into an embryo; the genetic and biochemical events underlying the early development of the embryo; the hormonal controls operating in the reproductive process; and the general control of implantation and growth of the mammalian embryo in the uterus. Thirteen reports were given by distinguished researchers in each of these areas. All biologists interested in a broad understanding of problems of reproduction will find this symposium interesting and important for their own work.

  • The Ontogeny of Vertebrate Behavior

    • 1st Edition
    • Howard Moltz
    • English
    The Ontogeny of Vertebrate Behavior is a collection of articles focused on the comparative psychology researches. The text is devoted to the development of vertebrate behavior, emphasizes the ontogenetic determinants, and answers questions related to the differentiation of selected response systems. The book is organized into 10 chapters that feature the concepts of vertebrate behavior and its ontogeny. It presents the study of behavioral development, as well as the visual perceptual systems and its evolution. It explains the perceptual abilities of the human infant and the early experience and problem-solving behavior. Cerebral effects of environmental manipulation and the behavioral phenomena are explained. The book also talks about the ontogeny of emotional, play, and exploratory behaviors; of sexuality and maternal behavior; and of mother-infant relations. It also discusses the principle and procedure of imprinting. Finally, it explains the vocal learning of avian species and the ontogeny of language, as well as the vocal abnormalities. This text will be invaluable to the students, novices, and professionals in psychology, ethology, endocrinology, and behavioral and developmental biology.

  • Biological Effects of Radiations

    • 2nd Edition
    • Daniel Grosch
    • English
    Biological Effects of Radiation, Second Edition aims to present an organized survey of the various experiments wherein living materials have been exposed to ionizing and exciting types of radiations. However, this book focuses on the effects of radiation to lower organisms, as these have received less attention. It tells how small amount of energy can damage submicroscopic structure and ultimately alter the appearance and abilities of such organisms. Divided into five parts, this book starts off with two introductory chapters in the first part. It explains the effects of radiation. Then, other parts of the book focus on the impact of radiation from cellular to organ level. How the lower organisms response is then discussed. Lastly, the book explains the interrelations between organisms in contaminated areas. Same with the first edition, emphasis is given on the consequences of mutations, as a whole chapter is devoted to this topic. Furthermore, this book covers discoveries from experiments with cultured cells. This book is a good text-reference for students and professionals. Also, it can be of great help to scientists, researchers, and specialists involved in the biological response to radiation.

  • Biology and Pathology of Nerve Growth

    • 1st Edition
    • Hsiang Mei Liu
    • English
    Biology and Pathology of Nerve Growth discusses the biochemical basis of cell interaction involved in nerve growth, regeneration, and diseases. This book contains six chapters that focus on neuron-glia interaction. After briefly dealing with the embryological development, this book goes on examining the process of neuronal maturation, myelination, and integration with target tissues. These topics are followed by discussions on the controversial issues of guidance and the nature of the factors that determine the matching of nerve with muscle from morphological and biochemical points of view. The subsequent chapters consider the principle of regeneration as seen in lower animals. Other chapters highlight the issue of reaction to injury. This book further demonstrates the interrelatedness of neural organization and reaction to injury at the cellular and molecular levels. This interrelationship operates on the same biophysical principles across all kinds of animal and plant species. This work is of great value to neurobiologists, developmental biologists, and pathologists.

  • Exotic Plant Pests and North American Agriculture

    • 1st Edition
    • Charles Wilson
    • English
    Exotic Plant Pests and North American Agriculture examines the threat posed by exotic pests introduced to North American agriculture. It considers the impact of introduced pests on humans, and it highlights the need for intensified research efforts and international cooperation to prevent further introductions. Organized into 17 chapters plus an epilogue, this volume begins with a historical overview of pest introductions, including insects and mites, and possible introductions in the future. It then discusses the impact of introduced weeds in North America; ecology and genetics of exotic species; how to detect and stop pest introductions; and research on exotic insects, plant pathogens, and weeds. The reader is also introduced to the use of exotic natural enemies for biological control of exotic pests, prediction of potential epidemics caused by exotic pests, insurance against exotic plant pathogens, and international cooperation on controlling exotic pests. Scientists, plant pathologists, ecologists, and those working in academics, government research laboratories, and regulatory agencies will benefit from reading this book.

  • Transporting Epithelia

    • 1st Edition
    • Michael Berridge
    • English
    Transporting Epithelia summarizes the progress that has been made in understanding a wide range of epithelial transport systems. This book discusses the epithelia involved in osmotic and ionic regulation from protonephridia to the mammalian kidney. It also explains the digestive and absorptive epithelia, as well as the epithelia that produce special secretions, such as milk, endolymph, aqueous humor, cerebrospinal fluid, sweat, and tears. Furthermore, this book describes the role of the epithelium in the physiology of the animal and the structure of the epithelium. Then, the structure of the epithelium is correlated with its physiological properties. This book will be valuable both for teaching and as a reference for research workers interested in comparative aspects of transport phenomena.

  • Food Protein Chemistry

    An Introduction for Food Scientists
    • 1st Edition
    • Joe Regenstein
    • English
    Food Protein Chemistry: An Introduction for Food Scientists discusses food proteins and how they are studied. Proteins are both biological entities and physicochemical compounds, and they will be examined in both contexts in this volume. The chemical and physical properties of proteins will be viewed from the perspective of chemists despite the fact that their use in the food supply emphasizes their biological nature. Key topics discussed include proteins as essential to life; amino acids; protein classification; selected proteins of the most important food systems; and protein structure. The book also includes chapters on protein measurement; protein purification; and spectral techniques for the study of proteins. The book requires readers to have the equivalent of the Institute of Food Technologists requirements for undergraduate food science majors. It also assumes a knowledge of math through calculus. While primarily intended for senior and first-year graduate food science students, the text may also be useful to researchers in allied fields.

  • Regulation of HMG-CoA Reductase

    • 1st Edition
    • Benjamin Preiss
    • English
    Regulation of HMG-CoA Reductase is a nine-chapter text that focuses on the research developments in the regulation of HMG-CoA reductase enzyme and cholesterol biosynthesis. This book deals first with the role of cholesterol in the regulation of its own biosynthesis and the work involving compactin and related competitive inhibitors of HMG-CoA reductase. The subsequent chapters examine the reversible phosphorylation of HMG-CoA reductase in hormonal and other short-term physiological changes and the structure and properties of the enzyme, including evidence for modulation of enzyme activity and structure unrelated to phosphorylation. These topics are followed by discussions on the regulation of reductase in the biosynthesis of ubiquinone, dolichols, and isopentenyl-tRNA and the regulation of reductase activity in extrahepatic tissues. This text further explores the contributions made through the use of cultured cells and their genetic manipulation, with emphasis on the great potential of this approach. The concluding chapters address the status of the low-density lipoprotein pathway and related mechanisms. These chapters also consider the regulation of human hepatic HMG-CoA reductase and the special problems inherent in work with human tissues. Enzyme scientists and researchers and graduate students will find this book invaluable.

  • Water Relations of Plants

    • 1st Edition
    • Paul J Kramer
    • English
    Water Relations of Plants attempts to explain the importance of water through a description of the factors that control the plant water balance and how they affect the physiological processes that determine the quantity and quality of growth. Organized into 13 chapters, this book first discusses the functions and properties of water and the plant cell water relations. Subsequent chapters focus on measurement and control of soil water, as well as growth and functions of root. This book also looks into the water absorption, the ascent of sap, the transpiration, and the water stress and its effects on plant processes and growth. This book will be useful for students, teachers, and investigators in both basic and applied plant science, as well as for botanists, agronomists, foresters, horticulturists, soil scientists, and even laymen with an interest in plant water relations.

  • Pollution Ecology of Estuarine Invertebrates

    • 1st Edition
    • C.W. Jr. Hart
    • English
    Pollution Ecology of Estuarine Invertebrates, as its companion volume ""Pollution Ecology of Freshwater Invertebrates"", aims to present the ecology of estuarine invertebrates and highlight some systematic interpretations. This book also discusses the knowledge about these invertebrates. It is a compilation of existing data at the time of writing, an attempt to introduce ideas and information, and a result of synthesis of systematic interpretations. This book consists of 12 chapters, each with a specific invertebrate as subject area. The invertebrates encompassed in this book are thread and bristle worms, Bryozoa, ostracods, copepods, crabs, shrimps, larval decapods, Cyathura, isopods (other than Cyathura), amphipods, clams, and snails. Each chapter gives a thorough discussion of the featured invertebrate according to some of the organism’s aspects, such as habitat, systematic, zoogeography, pollution ecology, life cycle, physiology, population, taxonomy, and distribution. This book is a valuable source for students, teachers, scientists, or researchers interested in estuarine invertebrates and pollution and study biology, environmental science, zoology, or even marine science.

  • Designing Antibodies

    • 1st Edition
    • Ruth Mayforth
    • English
    Designing Antibodies provides a compilation of research in the design of antibodies. It describes the techniques used in antibody design, the kinds of antibodies generated through modern techniques, and their applications in medicine and science. The book begins with an overview of the humoral immune system and of antibody structure, function, and biosynthesis, which sets the stage for the subsequent discussions of developments in antibody technology. The remaining chapters discuss the making of monoclonal antibodies; the design of antibodies for human therapy; the connection of antibodies (either chemically or genetically) to other potentially therapeutic effector molecules such as toxins, enzymes, or even an antibody of another specificity; idiotypes and anti-idiotypic antibodies; and the ability of antibodies to functionally mimic enzymes and mediate catalysis. It is hoped that, in addition to illustrating the progress of research in antibody design, the various creative and innovative approaches reviewed in this book will be modified or will stimulate new ideas that will spur the research and application of designer antibodies.

  • The Structure and Function of Skin

    • 3rd Edition
    • William Montagna
    • English
    The Structure and Function of Skin, Third Edition is devoted to all matters pertaining to the structure and function of the skin. Drawing upon the accumulated data derived from embryology, histology, anatomy, physiology, biochemistry, and pharmacology, this book presents an overview of skin, with emphasis on human skin. Topics range from the biological functions of the dermis to the histochemical and microchemical properties of the epidermis; the effects of protein deficiency on hair growth; cutaneous innervation; nail regeneration and growth; sebaceous glands; and eccrine sweat glands. This book is organized into 12 chapters and begins with an overview of the structure and function of skin, and then discusses the epidermis and its structural features. Special consideration is given to the life cycle of epidermal cells; the properties and function of stratum corneum; and other cells in the epidermis including melanocytes, the cells of Langerhans, and Merkel cells. The chapters that follow focus on age-related changes in the dermis, cutaneous blood flow, changes in skin circulation, and the dermal nerve network. The book also considers hair growth and differentiation; the effects of malnutrition on the morphology of hair roots; and the structure and development of the nails. A chapter describing the cytochemistry and pharmacology of eccrine sweat glands concludes the book. This book is written primarily for dermatologists, whether seasoned veterans or neophytes, and will also be useful to all biologists who are interested in biomedical disciplines.

  • Newer Methods of Nutritional Biochemistry V3

    With Applications and Interpretations
    • 1st Edition
    • Anthony Albanese
    • English
    Newer Methods of Nutritional Biochemistry: With Applications and Interpretations, Volume III, provides a compilation of biochemical procedures which have extensive applications in nutrition research. The focus is on simple procedures to evaluate the utilization of dietary proteins given the pressing problems in emergency feeding of populations in developing countries. Comprised of nine chapters, this book discusses the nutritional and metabolic implications of changes in urinary amino acid levels. It examines the concept, role, and implications of protein reserves in the young and adult subjects. It also describes procedures which have contributed to the development of in vitro methods for the evaluation of protein quality. The book also discusses plant protein resources; lipoprotein transport; chemical assay of adrenocorticosteroid... studies of zinc metabolism; and folates in human nutrition.

  • Pathology of Domestic Animals

    • 4th Edition
    • English
    The all-new Fourth Edition of Pathology of Domestic Animals comprehensively covers the biology and pathology of diseases of domestic animals on a systemic basic. Updated and expanded to reflect the current knowledge of the study of domestic animal diseases, this three-volume set appeals to veterinarians, veterinary students, trainee veterinary pathologists learning the scope of their field, and practicing pathologists confronted with diagnostic problems.

  • Basic sleep Mechanisms

    • 1st Edition
    • Olga Petre-Quadens
    • English
    Basic Sleep Mechanisms is a collection of studies about the different mechanisms that facilitate the process of sleep. The studies, despite being made by experts of different subspecialties, are more purposed for general interest. The book is divided into four parts. Part I covers the concepts under the neurophysiological mechanisms of sleep, such as the sleep-wake cycle, pontine stimulations of sleep, and the role of different parts of the nervous system in sleep. Part II includes topics under the neurochemical aspects of sleep and the role of monoaminergic neurons in it. Part III discusses the different three states of the adult human body, the direction in its research, and its psychological aspect. Part IV explains the developmental aspects of sleep, especially in infants and children. The text is recommended for neurologists, doctors, and psychologists who want to know more about the study or to conduct their own study about sleep, the principles behind it, and its development.

  • Nucleic Acid–Protein Recognition

    • 1st Edition
    • Henry Vogel
    • English
    Nucleic Acid-Protein Recognition covers the proceedings of a symposium on ""Nucleic Acid-Protein Recognition"", held at Arden House, Harriman Campus of Columbia University on May 30-June 1, 1976. The symposium inaugurated the ""P & S Biomedical Sciences Symposia"" under the sponsorship of the College of Physicians and Surgeons of Columbia University. This book is organized into nine part encompassing 31 chapters. The opening parts describe the principles of DNA replication and the unique chromatin structure. These parts also examine the physical chemistry of the interactions of melting proteins with nucleic acids. The third part presents the different types of approaches that can be used to study the function of RNA polymerases and the development of a cell-free system that favors Pol II-catalyzed transcription from type 2 adenovirus DNA. Parts IV and V deal with the sequence determination of wild-type and mutant repressor and the restriction and modification of DNA endonucleases, while parts VI and VII focus of the recognition of tRNA. Part VIII discusses some significant studies on the assembly of ribosomes and the principles of ribosomal interactions. Lastly, Part IX considers the role of small RNA template in the reaction mechanism of RNA replicases and ribonucleases. This part also surveys the so-called RNase III cleavage of different types of RNA and the structure of nucleic acid-protein complexes.

  • Plant Parasitic Nematodes

    • 1st Edition
    • Bert Zuckerman
    • English
    Plant Parasitic Nematodes, Volume III provides a comprehensive discussion of the different advances in plant nematology. This includes biochemical techniques to taxonomy and innovation in transmission and scanning electron microscopy technology. It explains a broadened basis for understanding nematode physiology and behavior and the sensory mechanisms that govern nematode actions and plant host-nematode interactions. The book discusses the development of modern approaches to the evaluation and reduction of crop losses. The emphasis of this volume is on plant parasites and insights gained through research on other nematodes. In particular, the book explains the anatomical, developmental, behavioral, and genetic studies on the free-living nematode Cenorhabditis elegans, which is a widely used laboratory model for examining various biological problems. The information provided by various researches on C. elegans increases our understanding about the relevance of nematodes to general biological processes in higher organisms, including man. The book is divided into 19 chapters which cover the following concepts of plant nematology: biochemistry, cytochemistry, and genetics; morphology and function; host-parasite relations; and evaluation and control of crop losses. The present volume is an excellent reference for students, lecturers, and research professionals in plant parasitology and related fields.

  • The Psychophysiology of Thinking

    Studies of Covert Processes
    • 1st Edition
    • F Mcguigan
    • English
    The Psychophysiology of Thinking: Studies of Covert Processes describes the relation between brain events and peripheral bodily phenomena in the context of psychological theory. This book is organized into six parts encompassing 14 chapters, which focus on higher mental processes. This book starts with the historical development of electrical measures of covert processes. The subsequent chapters discuss the mechanism of conditioning of central nervous system, the skeletal musculature, and the autonomic activity. Other chapters explore the principles of hallucinations, sleep and dreaming, imagery, biofeedback, evoked potentials during thought, meaning, and thought with concomitant measures. The remaining chapters emphasize cerebral mechanisms, which principal concern is with the involvement of other bodily mechanisms in thought. Psychophysiologists, neurobiologists, behaviorists, and researchers in the fields of thinking and covert processes will find this book invaluable.

  • Breastfeeding and Food Policy in a Hungry World

    • 1st Edition
    • Dana Raphael
    • English
    Breastfeeding and Food Policy in a Hungry World documents the proceedings of the International Conference on Human Lactation held by the New York Academy of Sciences in March 1977. The contributions made by researchers at the conference are organized into five sections. Section One presents studies on the family contexts of breastfeeding and social myths and economic realities of breastfeeding. Section Two examines cultural factors in infant feeding practices, including breastfeeding practices of women in India, Nigeria, and China. Section Three deals with the economic and commercial aspects of infant weaning foods. It includes studies on economics of food aid programs; the difficult problems involved in developing a dairy industry in warm climates; and the effects on breastfeeding of the present political climate. Section Four presents studies on physiological, psychological, public health, and political considerations in human lactation. Section Five describes several programs designed to improve the health of children. These include nonformal education to help women help themselves and their families, and food subsidies and decentralization of service to improve the health of poor people.

  • Human Reproductive Biology

    • 1st Edition
    • Mark M. Jones
    • English
    Human Reproductive Biology focuses on the processes, concerns, and trends in human reproduction. Divided into four parts with 19 chapters, the book starts by tracing the history of human reproduction biology and the questions and choices involved. The first part focuses on the male and female reproductive systems. The text notes the different organs involved in reproduction, including the penis, scrotum, vagina, oviducts, and mammary glands. The book discusses sexual development and differentiation, particularly noting the variance of sex ducts and glands, external genitalia, and disorders of sexual development and determination. The text also looks at puberty. Concerns include gonadal changes from birth to puberty; mechanisms that influence puberty; and puberty and psychosocial adjustment. The second part deals with menstrual cycle, fertilization, pregnancy, labor, and birth. Some of the concerns include length of menstrual cycle; absence of menstruation; transport of sperm and ovum in the oviduct; and semen release. The text also highlights labor and birthing processes as well as the relationship of neonates and parents. The third part looks at the medical aspects of human reproduction, infertility, and sexually transmitted diseases. Concerns include contraception, abortion, herpes genitalis, and vaginitis. The text folds with discussions on human sexual behavior, population growth, and family planning. Concerns include sexual dysfunction; the effects of overpopulation; and population control. The book is a vital source of data for readers interested in human reproduction.

  • Prostaglandin synthesis

    • 1st Edition
    • Jasjit Bindra
    • English
    Prostaglandin Synthesis reviews the developments in the preparation and isolation of prostaglandins by synthesis, with emphasis on the more promising and significant approaches. It includes a nomenclature of prostaglandins and considers prostaglandin analogs as well as their structure-activity relationships, prostaglandin interconversions, isomeric prostaglandins, and deoxyprostaglandins. Organized into 21 chapters, this book begins with an overview of prostaglandin biosynthesis and the potential clinical utility of prostaglandins. It then discusses the discovery of prostaglandins and the isolation of prostaglandins E and F, format for structural presentation of prostaglandins, closure of the cyclopentane ring from acyclic precursors, and conjugate addition of organometallic derivatives to alpha-substituted cyclopentenones. It explains the cyclohexane and bicyclohexane precursors, Corey's synthesis of bicyclohexane precursors, bicyclooctane and bicyclononane precursors, and approaches to synthesis of A, B, C, and D prostaglandins. This book is a valuable resource for biochemists and others working in the field of prostaglandin biosynthesis.

  • Inhibition and Destruction of the Microbial Cell

    • 1st Edition
    • W Hugo
    • English
    Inhibition and Destruction of the Microbial Cell focuses on the effects of various classes of toxic chemical agents on microbial cell. This book is organized into 14 chapters that cover the topics from two points of view: the agent and the target (the microbial cell). The introductory chapters are devoted to the inhibitory effects of elevating temperature and to the lethal effect of environmental thermal energy supply restriction on growing bacteria. A chapter focuses on the effect of various classes of antibacterial compounds, such as 4-amino-quinaldinium and 8-hydroxyquinoline derivatives, chlorhexidine, amidines, halogens, dyes, and nitrofurans. The subsequent chapters examine the effects of other chemical agents on microorganisms, including toxic gases, solutes, ions, and radiations. The book goes on examining the inhibition and destruction of specific microorganisms, such as Pseudomonas aeruginosa, Enterobacteriaceae, Mycobacteria, Cocci, bacterial spores, molds, yeasts, and viruses. The last chapter discusses the effect of the cultural prehistory of microorganisms upon their response to inhibition and destruction. This book is an invaluable resource for graduate research workers and scientists in pure and applied microbiology. This will also be a good reference for undergraduates reading specialized courses at honors level in microbiology or applied courses in food science and agriculture. Furthermore, it will be of interest to the medical profession, especially those involved in public health and pathology, as well as to scientists in the pharmaceutical industry.

  • Neural Control of Circulation

    • 1st Edition
    • Maysie Hurnes
    • English
    Neural Control of Circulation presents an in-depth view of specialized areas in the neural regulation of the circulatory system that have been the subject of intensive research, the historical basis and theory from which those investigations evolved, and directions for future studies. Special emphasis is placed on critical evaluation of the experimental data in each field of research. This volume is comprised of seven chapters and begins with a synthesis of a large number of studies undertaken using conscious animals, particularly those that focuses on the behavioral and cerebral control of cardiovascular function. The second chapter explores the role of the brain stem and cerebellum in cardiovascular control. Next, specific research areas concerning bulbospinal control of sympathetic nerve discharge are discussed. This is followed by a chapter devoted to the nucleus tractus solitarii and experimental neurogenic hypertension. A concept in potential hypertensive mechanisms involving long-term transsynaptic regulation of adrenal medullary function is also described, and the neural control of the circulation during hypoxia is considered. Finally, aspects of central nervous system pharmacology and regulation of circulation are examined. This book is designed for individuals who are interested in the cardiovascular system and its function, and should also prove useful to students and researchers in physiology and individuals in other ancillary areas of bioscience.

  • Fibronectin

    • 1st Edition
    • Deane Mosher
    • English
    Fibronectin presents the studies made on the physiological and pathophysiological roles of fibronectin. The book presents chapters that discuss the primary structure of fibronectin and its mRNA; the physicochemical properties of fibronectin and fibronectin fragments; the fibronectin-containi... extracellular matrix; the relationship of fibronectin and fibronectin-containi... matrix to embryogenesis, wound healing, and the biology of cancer cells; the roles of fibronectin in platelet aggregation, attachment of microorganisms, pathogenesis of kidney diseases, arthritis, and lung fibrosis; and the production of purified concentrates of fibronectin suitable for use in patients. The book will be of much interest to biologists, biochemists, pharmacologists, and medical practitioners and researchers.

  • Physiological Psychology

    • 1st Edition
    • Thomas Brown
    • English
    Physiological Psychology explores the trends in physiological psychology, a rapidly growing and changing field that deals with the relationship between physiology and behavior. It considers the physiological correlates of emotions and how emotions are related to specific kinds of brain activity, the plasticity of the nervous system as it relates to learning and memory, and higher processes, such as thinking, decision making, reasoning, and language. Organized into 16 chapters, the book begins with an overview of the nervous system and the neuron, emphasizing the sensory systems: vision, audition, the chemical senses (olfaction and taste), and the somatosensory and vestibular systems. Then, it discusses the physiological bases of some of the more ""primitive"" behaviors, such as hunger, thirst, reproduction, sleep, and emotion. In particular, it examines the motor system of the brain, the motivation for food and water, the biological bases of sexual behavior, the biological rhythms and sleep, and the role of genetics, nutrition, environment, and hormones in development. The last chapter deals with the cortex and its role in the higher processes. This book is a valuable resource for psychologists, biologists, chemists, physicists, engineers, nutritionists, and many others interested in the relationship between biology and behavior.

  • Bivalvia Through Reptilia

    • 1st Edition
    • T Pandian
    • English
    Animal Energetics, Volume 2: Bivalvia through Reptilia is part of a two-volume treatise focusing on the integrated picture of the energy transformation process at the organismic level. Since it is almost impossible to restrict meaningful discussions to only one level of organization, some reference is made to population energetics as well as to the suborganismic level. The bioenergetics of both vertebrate and invertebrate groups are discussed. Specifically, the bioenergetics of bivalves, gastropods, bryozoans, pogonophorans, echinoderms, lower chordates, fishes, amphibians, and reptiles are covered. Understanding the efficient and fast transformation of biological energy has become an important issue in world affairs; studies on energetics and growth of thermoconformers can therefore be expected to expand greatly in the future. This book aims to provide many keys to a broader understanding of biology as well as open untrodden avenues to biologists with the quest for newer energy sources and efficient methods of energy utilization.

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