Prostaglandin synthesis
- 1st Edition - January 1, 1977
- Author: Jasjit Bindra
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 0 9 9 4 6 0 - 1
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 1 4 3 6 1 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 4 6 7 8 - 4
Prostaglandin Synthesis reviews the developments in the preparation and isolation of prostaglandins by synthesis, with emphasis on the more promising and significant approaches. It… Read more
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Request a sales quoteProstaglandin Synthesis reviews the developments in the preparation and isolation of prostaglandins by synthesis, with emphasis on the more promising and significant approaches. It includes a nomenclature of prostaglandins and considers prostaglandin analogs as well as their structure-activity relationships, prostaglandin interconversions, isomeric prostaglandins, and deoxyprostaglandins. Organized into 21 chapters, this book begins with an overview of prostaglandin biosynthesis and the potential clinical utility of prostaglandins. It then discusses the discovery of prostaglandins and the isolation of prostaglandins E and F, format for structural presentation of prostaglandins, closure of the cyclopentane ring from acyclic precursors, and conjugate addition of organometallic derivatives to alpha-substituted cyclopentenones. It explains the cyclohexane and bicyclohexane precursors, Corey's synthesis of bicyclohexane precursors, bicyclooctane and bicyclononane precursors, and approaches to synthesis of A, B, C, and D prostaglandins. This book is a valuable resource for biochemists and others working in the field of prostaglandin biosynthesis.
Preface
Acknowledgements
Conventions
1. Introduction
2. Isolation and Structure
3. Nomenclature
4. Prostaglandin Syntheses
5. Acyclic Precursors
6. Cyclopentane Precursors
7. Cyclopentane Precursors — Conjugate Addition Approaches
8. Cyclohexane Precursors
9. Bicyclohexane Precursors
10. Bicycloheptane Precursors — Corey's Synthesis
11. Bicycloheptane Precursors — Miscellaneous Approaches
12. Bicyclooctane Precursors
13. Bicyclononane Precursors
14. A Prostaglandins
15. B Prostaglandins
16. C Prostaglandins
17. D Prostaglandins
18. Prostaglandin Interconversions
19. Isomerie Prostaglandins
20. Deoxyprostaglandins
21. Prostaglandin Analogs
Appendix: Selected Reviews
Index
- No. of pages: 536
- Language: English
- Edition: 1
- Published: January 1, 1977
- Imprint: Academic Press
- Hardback ISBN: 9780120994601
- Paperback ISBN: 9780124143616
- eBook ISBN: 9780323146784
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