Limited Offer
Natural Cell-Mediated Immunity Against Tumors
- 1st Edition - January 1, 1980
- Editor: Ronald Herberman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 4 1 3 5 0 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 4 1 7 3 - 4
Natural Cell-Mediated Immunity Against Tumors aims to be the first book to provide a comprehensive discussion on natural cell-mediated immunity against tumors. This book is mostly… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteNatural Cell-Mediated Immunity Against Tumors aims to be the first book to provide a comprehensive discussion on natural cell-mediated immunity against tumors. This book is mostly a collection of different research contributed by leading laboratories. It also presents a better perspective of how natural mechanisms fit in with and relate to the traditional and more extensively studied components of the immune system. The book starts off with an overview of the contents of the volume – the historical development of the advances in the field of research and the status of knowledge in the subject area. Divided into four major sections, the book consists of a total of 98 chapters. The sections discuss the natural killer cells and related cells and the natural lymphokine production. This book also explains the natural macrophage and granulocyte cytotoxicity. The book will be a helpful reference for students, professionals, and researchers in biology, immunology, biochemistry, microbiology, and other related fields.
Participants
Preface
Section I Natural Killer (NK) Cells and Related Cells
A Characteristics of NK and Related Cells
Characteristics of NK and Related Cells
Alloantisera Selectively Reactive with NK Cells: Characterization and Use in Defining NK Cell Classes
Asialo GMl and Thy 1 as Cell Surface Markers of Murine NK Cells
Characteristics of Natural Cytostatic Effector Cells
Characterization of the NK Cell in Man and Rodents
Characteristics of Murine NK Cells in Relation to T Lymphocytes and K Cells
Characteristics of NK Cells
Antigenic Phenotype of Mouse Natural Killer Cells
Natural Cytotoxicity of Macrophage Precursor Cells and of Mature MacrophageS
Centrifugal Elutriation Allows Enrichment of Natural Killing and Separates Xenogeneic and Allogeneic Reactivity
Effects of Alloantisera on Murine K and NK Cell Activity
Characteristics of Human Natural Killer Cells
Phenotypic Characteristics of NK Cells in the Mouse
Morphology and Surface Properties of Human NK Cells
Natural Cytotoxic (NC) Cells against Solid Tumors in Mice: General Characteristics and Comparison to Natural Killer (NK) Cells
Ontogeny and Other Age-Related Effects of Natural Cytotoxic (NC) Cells in Mice
Biophysical and Serological Characterization of Murine NK Cells
Analysis of Recognition Patterns of NK Cells through Use of Varying Combinations of Mouse Strains and Tumor Targets
FACS Analysis and Enrichment of NK Effector Cells
B Mechanism of Cytotoxicity by NK Cells and Their Relationship to K Cells
Summary: Characteristics of NK and Related Cells
Mechanism of Cytotoxicity by NK Cells and Their Relationship to K Cells
Quantitation of Human Natural and Antibody-Dependent Cytotoxicity
The Relationship between Natural and Antibody-Dependent Cell-Mediated Cytotoxicity
Differential Effects of Immune Complexes on Human Natural and Antibody-Dependent Cell-Mediated Cytotoxicity
Natural Killing and Antibody-Dependent Cellular Cytotoxicity: Independent Mechanisms Mediated by Overlapping Cell
Are Spontaneous and Antibody-Dependent Lysis Two Different Mechanisms of Cytotoxicity Mediated by the Same Cell?
A Comparative Analysis of the NK Cytolytic Mechanism and Regulatory Genes
Summary: Mechanism of Cytotoxicity by NK Cells and Their Relationship to K Cells
C1 Immunogenetic Regulation of NK Activity
Immunogenetics of Natural Immunity
Augmentation of Natural Killer Cell Activity of Beige Mice by Interferon and Interferon Inducers
Mutations That Influence Natural Cell-Mediated Cytotoxicity in Rodents
Genetic Influences Affecting Natural Cytotoxic (NC) Cells in Mice
Summary: Immunogenetic Regulation of NK Activity
C2 Development of NK Activity during in Vitro Culture
Development of NK Activity during in Vitro Culture
In Vitro Development of Human NK Cells: Characteristics of Precursors and Effector Cells and Possible Cell Lineage
MLC-Induced Cytotoxicity against NK-Sensitive Targets
Summary: Development of NK Activity during in Vitro Culture
C3 Augmentation of NK Activity
Interferon and NK Cells in Resistance to Persistently Virus-Infected Cells and Tumors
Interferon-Independent Activation of Murine Natural Killer Cell Activity
Enhancement of Human NK Activity by Interferon. In Vivo and in Vitro Studies
Regulatory Factors in Human Natural and Antibody-Dependent Cell-Mediated Cytotoxicity
Spontaneous Cell-Mediated Cytotoxicity (SCMC) and Short-Term Mixed Leukocyte Culture (MLC): Role of Soluble Factors and of Cellular Interactions
Augmentation of Human NK and ADCC by Interferon
Factors Controlling the Augmentation of Natural Killer Cells
Characteristics of Augmentation by Interferon of Cell-Mediated Cytotoxicity
Spontaneous Cell-Mediated Cytotoxicity (SCMC): Enhancement by Interferons and Corynebacterium Parvum-Induced T-Cell Factor(s) Lacking Antiviral Activity
Modulation of Natural Cytotoxicity in Man by BCG and Fibroblast Interferon
Regulation of Human Natural Killer Activity by Interferon
Spontaneous Cell-Mediated Cytotoxicity: Modulation by Interferon
Activated Natural Killer Cells Induced during the Lymphocytic Choriomeningitis Virus Infection in Mice
Augmentation of Human Natural Killer Cell Activity by Purified Interferon and Polyribonucleotides
Summary: Augmentation of NK Activity
C4 Suppression or Inhibition of NK Activity
Prostaglandin-Mediated Inhibition of Murine Natural Killer Cell Activity
C. Parvum-Mediated Suppression of the Phenomenon of Natural Killing and Its Analysis
Inhibition As Well As Augmentation of Mouse NK Activity by Pyran Copolymer and Adriamycin
The Effect of 17/3-Estradiol on Natural Killing in the Mouse
Summary: Suppression or Inhibition of NK Activity
D Specificity of Cytotoxicity by NK Cells and Nature of Recognition Structures on Effector and Target Cells
Comparison of Natural Immunity to MTV and Natural Killer Reactivity
The Use of Lymphoma Cell Variants Differing in Their Susceptibility to NK Cell-Mediated Lysis to Analyse NK Cell- Target Cell Interactions
Kinetic Analysis of Specificity in Human Natural Cell-Mediated Cytotoxicity
Human Natural Cell-Mediated Cytotoxicity: A Polyspecific System
Interaction between NK Cells and Normal Tissue: Definition of a NK-Sensitive Thymocyte Population
Specificity of NK Cells
Heterogeneity in Natural Killing
Are Natural Killer Cells Germ-Line V-Gene-Encoded Prothymocytes Specific for Self and Nonself Histocompatibility Antigens?
Natural and Activated Lymphocyte Killers which Affect Tumor Cells
Murine Retrovirus—Specific Natural Killer Cell Activity
The Specificity of NK Cells at the Level of Target Antigens and Recognition Receptors
Natural Cytotoxic (NC) Cells against Solid Tumors in Mice: Some Target Cell Characteristics and Blocking of Cytotoxicity by D-Mannose
Modification of Target Susceptibility to Activated Mouse NK Cells by Interferon and Virus Infections
Summary: Specificity of Cytotoxicity by NK Cells and Nature of Recognition Structures on Effector and Target Cells
E NK Aactivity during Carcinogenesis and Tumor Growth and Its Expression within Tumors
Intratumor NK Reactivity
Cytotoxicity and Cytostasis Mediated by Splenocytes of Mice Subjected to Chemical Carcinogens and of Mice-Bearing
NK Cell Activity in the Blood, Tumor-Draining Lymph Nodes, and Primary Tumors of Women with Mammary Carcinoma
Natural Cell-Mediated Cytotoxicity in Human Tumor Patients
Systemic and in Situ Natural Killer Activity in Tumor-Bearing Mice and Patients with Cancer
Natural Killer Cells in Tumor-Bearing Patients
Natural Cytotoxic (NC) Cells in Tumor-Bearing Mice
Natural Killers in Human Cancer: Activity of Tumor-Infiltrating and Draining Node Lymphocytes
Summary: NK Activity during Carcinogenesis and Tumor Growth and Its Expression within Tumors
F In Vivo Role of NK Cells in Host Defense
In Vivo Activity of Murine NK Cells
Analogy between Rejection of Hemopoietic Transplants and Natural Killing
Role of NK Cells in Rapid in Vivo Clearance of Radiolabeled Tumor Cells
Summary: In Vivo Role of NK Cells in Host Defense
G Natural Immunity and Resistance Against Microbial Agents
Natural Resistance of Mice toward Orthomyxoviruses
Natural Macrophage Cytotoxicity against Protozoa
Natural Killer Cell Activity against Virus-Infected Cells
Summary: Natural Immunity and Resistance against Microbial Agents
Section II Natural Lymphokine Production
Interferon Production in Murine Spleen Cell Cultures
Natural Production of Macrophage-Migration Inhibitory Factor and Human-Leukocyte Inhibitory Factor
Interferon Production in Lymphocytes Cultured with Tumor-Derived Cells
Summary: Natural Lymphokine Production
Section III Natural Macrophage Cytotoxicity
Regulatory Capacities of Mononuclear Phagocytes with Particular Reference to Natural Immunity against Tumors
Natural Cytotoxicity on Tumor Cells of Human Monocytes and Macrophages
Summary: Natural Macrophage Cytotoxicity
Section IV Natural Granulocyte Cytotoxicity
The Role of Granulocytes in Host Defense against Tumors
Summary: Natural Granulocyte Cytotoxicity
Index
- No. of pages: 1344
- Language: English
- Edition: 1
- Published: January 1, 1980
- Imprint: Academic Press
- Hardback ISBN: 9780123413505
- eBook ISBN: 9780323141734