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Elsevier

Books in Life sciences

  • Neurology

    What Shall I Do?
    • 1st Edition
    • Dafydd Thomas + 1 more
    • English
    Neurology: What shall I do? is a question and answer book that addresses the different kinds of neurological problems encountered by physicians everyday. The text serves as a quick reference guide for doctors and presents practical and simple approaches to certain neurological situations. The questions are grouped under broad headings such as epilepsy, headaches, weakness, fatigue, narcolepsy, and spinal problems. Answers to questions on pain problems, urinary difficulty, and how to categorize urgent and non-urgent cases are presented as well. Physicians, surgeons, and medical students will find the book very useful.

  • Cellular and Molecular Mechanisms of Inflammation

    Vascular Adhesion Molecules
    • 1st Edition
    • Charles G. Cochrane + 1 more
    • English
    Cellular and Molecular Mechanisms of Inflammation: Vascular Adhesion Molecules presents the study of the structure and function of constitutive and inducible cell surface structures, which contribute to the temporal and spatial patterns, and cellular selectivity of leukocyte-vessel wall interactions. The book addresses the rapidly expanding field of vascular adhesion molecules. Contributed articles discuss SELECTINS, a family of structurally related glycoproteins that contain lectin like domains that confer leukocyte-selective adhesive functions, which include ELAM-1 (Endothelial-Leukocy... Adhesion Molecule-1), GMP-140 (PADGEM, CD62), and LAM-1 (gp 90m e l, LEC-CAM-1, LECAM-1). Other adhesive molecules such as CD44 and members of the immunoglobulin family of cell surface glycoprotiens, including ICAM-1 (CD54), VCAM-1/ INCAM-110 and LP AM-1 are also considered. The text will be very useful to cytologists, molecular biologists, physiologists, and pharmacologists.

  • Biological Cycles

    Current Topics in Cellular Regulation, Vol. 18
    • 1st Edition
    • Ronald W. Estabrook + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 18: Biological Cycles covers topics on the events of molecular biology, cellular communication, and the merging of cell structure to biochemical function. The book discusses the ornithin-urea cycle; the cycles of glutathione metabolism and transport; and the role of multienzymatic proteins in mammalian pyrimidine biosynthesis. The text also describes the significance of interconvertible enzyme cycles in cellular regulation; regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-deph... cycle; replenishment of citric acid cycle intermediates by the purine nucleotide cycle in rat skeletal muscle. The control of a secondary pathway of ethanol metabolism by differences in redox state; the role of aldolase and fructose bisphosphatase in the control of gluconeogenesis and glycolysis; and the fructose 6-phosphate/fructose 1,6-bisphosphate cycle are also considered. The book further tackles the cycles in polysaccharide biosynthesis and other important biological cycles. Biologists, microbiologists, cellular biologists, and biochemists will find the book invaluable.

  • Sectional Anatomy and Tomography of the Head

    • 1st Edition
    • Guy D. Potter
    • English
    Sectional Anatomy & Tomography of the Head focuses on the anatomical section of the head and its description. It discusses the slowly developing appearance of the head which includes the face, orbit, ears, sinuses, and base of the skull. It addresses the functions and structures of such parts. Some of the topics covered in the book are the anatomic section, radiographs, line drawings, and tomography of the coronal head, the lateral head, axial head, and oblique head. The frontal, lateral, axial, and oblique positions of the head are covered. A study of the axial features of the head is also presented. A chapter is devoted to the bone structures of the oblique area of the head. Another section focuses on the description of orbit, optic canal, nasal fossa, and temporal bone. The book can provide useful information to doctors, neurosurgeons, students, and researchers.

  • Marihuana Biological Effects

    Analysis, Metabolism, Cellular Responses, Reproduction and Brain
    • 1st Edition
    • Gabriel G. Nahas + 1 more
    • English
    Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held at Paris on July 22-23, 1978. Organized into four parts, this book begins with a discussion on the quantification of cannabinoids and their metabolites in the body fluids and tissues. Part II describes the cannabinoids and cellular metabolism. Parts III and IV explain the effects of cannabis on reproduction and brain.

  • Fetal Endocrinology

    • 1st Edition
    • Miles J. Novy + 1 more
    • English
    Fetal Endocrinology covers many facets of primate reproductive biology. The book discusses some thoughts on the fetoplacental unit and parturition in primates; the development and function of the human fetal adrenal cortex; and postnatum evolution of the adrenal glands of rhesus macaques. The text also describes the regulation of fetoplacental steroidogenesis in rhesus macaque; the comparative biological, immunologic, and chemical properties of the primate chorionic gonadotropins; and urinary estrogens during pregnancy in diverse species. The secretion and physiology of chorionic somatomammotropin in primates; the placental thyroid stimulators and thyroid function in pregnancy; and growth factors in fetal growth and development are also considered. The book further tackles the production and activity of placental releasing hormone; the endocrinology of parturition; and sex-determining genes and gene regulation. The text also looks into the testicular hormone production in fetal rhesus macaque; the control of pituitary gonadotropin secretion in fetal rhesus macaque; and the development of the regulatory mechanisms of the hypothalamic-pituita... system in the human fetus. The development of the fetal adrenals in nonhuman primates and perspectives in fetal endocrinology are also encompassed. Reproductive physiologists, pediatricians, gynecologists, and endocrinologists will find the book invaluable.

  • The Exergy Method of Thermal Plant Analysis

    • 1st Edition
    • T. J. Kotas
    • English
    The Exergy Method of Thermal Plant Analysis aims to discuss the history, related concepts, applications, and development of the Exergy Method - analysis technique that uses the Second Law of Thermodynamics as the basis of evaluation of thermodynamic loss. The book, after an introduction to thermodynamics and its related concepts, covers concepts related to exergy, such as physical and chemical exergy, exergy concepts for a control method and a closed-system analysis, the exergy analysis of simple processes, and the thermocentric applications of exergy. A seven-part appendix is also included. Appendices A-D covers miscellaneous information on exergy, and Appendix E features charts of thermodynamic properties. Appendix F is a glossary of terms, and Appendix G contains the list of references. The text is recommended for physicists who would like to know more about the Exergy Method, its underlying principles, and its applications not only in thermal plant analysis but also in certain areas.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 6
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals... X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals... and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.

  • Phase and Caste Determination in Insects

    Endocrine Aspects
    • 1st Edition
    • Martin Lüscher
    • English
    Phase and Caste Determination in Insects: Endocrine Aspects is a collection of papers presented at a Symposium of the Section Physiology and Biochemistry of the XV International Congress of Entomology, held in Washington, D.C. in 1976. Contributors explore the endocrine aspects of phase and caste differentiation in insects, with emphasis on the crucial roles of juvenile hormone (JH) and queen bee determinator. This book is comprised of 11 chapters and begins with a discussion on the role of JH in caste formation in honey bees, bumblebees, and termites. Subsequent chapters explore environmental, genetic, and endocrine influences in caste determination in the stingless bee; endocrine control over caste differentiation in higher termites and Myrmicine ants; the influence of external factors on hormone effects in termite caste determination; and the role of JH in the polymorphism of aphids. The final chapter deals with the regulation of aphid polymorphism by neurosecretory cells. This monograph will be a valuable resource for entomologists, endocrinologists, physiologists, and biochemists as well as insect enthusiasts.

  • Recent Progress in Hormone Research - Volume 50

    Proceedings of the 1993 Laurentian Hormone Conference
    • 1st Edition
    • C. Wayne Bardin
    • English
    Recent Progress in Hormone Research, Volume 50: Proceedings of the 1993 Laurentian Hormone Conference focuses on the advancements of processes, methodologies, techniques, and approaches involved in hormone research. The selection first offers information on the molecular design of the NMDA receptor channel; synthesis and signaling of growth hormone-releasing hormone; and signaling mechanisms during the response of pituitary gonadotropes to GnRH. The discussions focus on calcium economy of gonadotropes, role of oscillations, structure and expression of the GHRH gene, transgenic animal models for GHRH action, and functional determinants in NMDA receptors. The text then elaborates on signaling mechanisms during the response of pituitary gonadotropes to GnRH; molecular genetic analysis of cAMP and glucocorticoid signaling in development; and activins and the receptor serine kinase superfamily. The publication takes a look at MAP kinase cascade, expression and signal transduction pathways of gonadotropin-releasi... hormone receptors, ovarian cell differentiation, and the role of oxytocin and its receptor in parturition. The book also examines the role of prolactin in developmental differentiation of hypophysiotropic tuberoinfundibular dopaminergic neurons and calcitonin gene expression in rat uterus during pregnancy. The selection is a valuable source of data for researchers interested in hormone research.

  • Classes of Pesticides

    • 1st Edition
    • Wayland J. Hayes Jr.
    • English
    Handbook of Pesticide Toxicology, Volume 3: Classes of Pesticides focuses on the properties, toxicity, classes, and reactions of pesticides. The selection first offers information on carbamate insecticides, nitro compounds and related phenolic pesticides, and synthetic organic rodenticides. Discussions focus on miscellaneous synthetic organic rodenticides, fluoroacetic acid and its derivatives, mononitrophenols, dinitrophenols, classification of carbamates, and toxicology of anticholinesterase carbamates. The book then examines herbicides and fungicides and related compounds. Topics include nitrogen heterocyclic fungicides not otherwise classified, hydrazines, hydrozones, and diazo fungicides, anilino and nitrobenzenoid fungicides, antibiotics and botanicals, organic phosphorus herbicides, carbamate herbicides, and herbicidal oils and simple aliphatics. The publication elaborates on miscellaneous pesticides, including repellents, synthetic molluscicides, inhibitors of chitin synthesis, chemosterilants, and synthetic acaricides. The selection is a valuable source of data for researchers interested in pesticide toxicology.

  • Neural Models of Plasticity

    Experimental and Theoretical Approaches
    • 1st Edition
    • John H. Byrne + 1 more
    • English
    Neural Models of Plasticity: Experimental and Theoretical Approaches is an outgrowth of a conference that was held at Woods Hole, Massachusetts, in the spring of 1987. The purpose of that conference was to review recent developments in both areas and to foster communication between those researchers pursuing theoretical approaches and those pursuing more empirical approaches. Contributions have been solicited from individuals who represent both ends of the spectrum of approaches as well as those using a combination of the two. These indicate that our knowledge of the plastic capabilities of the nervous system is accelerating rapidly due to rapid advances in the understanding of basic subcellular and molecular mechanisms of plasticity, and because of the computational capabilities and plastic properties that emerge from neural networks and assemblies. The book contains 19 chapters and opens with a study on the role of the neuromodulator in associative learning of the marine mollusk Hermissend. Subsequent chapters examine topics such as learning and memory in Aplysia; the Hebb rule for synaptic plasticity; olfactory processing and associative memory in the mollusk Limax maximus; simulation of a classically conditioned response; and the neural substrates of memory, focusing on the role of the hippocampus.

  • Comparative Experiments with Field Crops

    • 1st Edition
    • G.V. Dyke
    • English
    Comparative Experiments with Field Crops is a guide on how to organize comparative experiments about field crops. The book is divided into two parts. Part I deals with how to do and interpret field experiments; the planning of field experiments and special considerations to take into mind; the marking out, sowing, counting, and scoring of field crops; and the harvest as well as sampling. Part II covers the statistics involved in field experiments, and include comparisons and degrees of freedom and error; multidimensional geometry; regression analysis; and analysis of covariance. The text is recommended for agriculturists and botanists who intend to make a comparative study on field crops and are in need of a reference.

  • Advances in Drug Research

    Volume 12
    • 1st Edition
    • N. J. Harper + 1 more
    • English
    Advances in Drug Research, Volume 12 covers articles on advances in drug research. The book presents articles on cyclic nucleotides as targets for drug design; the opposing regulatory roles of cyclic nucleotides in the heart; and the integrated control of trematode diseases. The text also includes articles about the chemical and biological studies on indomethacin, sulindac and their analogs; as well as the pharmacokinetics, pharmacodynamics, toxicity, and the effects of bromocriptine. Toxicologists, pharmacologists, physicians, and drug researchers will find the book invaluable.

  • Kidney and Body Fluids

    Proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980
    • 1st Edition
    • L. Takács
    • English
    Advances in Physiological Sciences, Volume 11: Kidney and Body Fluids offers a thorough discussion of the experiments, research, and investigations done on the function, composition, and chemical reactions the kidney and body fluids undergo. Divided into 10 parts and having 88 chapters, the book features lengthy literature of authors who have actively pursued research on kidney and body fluids. Areas covered include renal cell cultures and blood flow; glomerulotubular balance; cell ionic activity and element analysis; electrophysiology and epithelial transport; and tubular handling of phosphate and calcium. Tubular acidification, regulation of water balance, and extracellular volume control are also discussed. The text presents as well how the study of the kidney and body fluids have captured the interest of physiologists and other individuals interested in this discipline. The book is a dependable source of information for those interested in the composition, function, and chemical reactions of the kidney and body fluids. The text is highly recommended to scholars and students who find this field of study interesting.

  • Research Surgery and Care of the Research Animal

    Patient Care, Vascular Access, and Telemetry
    • 1st Edition
    • William I. Gay + 1 more
    • English
    Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part A is a collection of papers that deals with methods used in animal experiments involving patient care, vascular access, and telemetry. This book concerns technologies in experimental surgery — complicated procedures requiring longer observation time of the test animal, and an increase in the spectrum of animals that can be used. One paper describes the anesthesia, analgesia, and kinds of restraints that are suited for the test animal. A wide array of choices of inhalational agents, injectable, local anesthesia (lidocaine), analgesics (opioids and aspirin), and restraint (nonanesthesia and neuromuscular-blocki... agents) is available for the researcher to choose from. Several authors also describe the use of telemetry devices that are implantable in test animals to achieve minimal interference from the investigator. These devices include sensors such as flow transducers and probes to use in pulse or continuous wave-applications; electromagnetic flowmeters for blood monitoring; and integrated circuits for various applications. One paper discusses postoperative care including a patient care checklist, treatment of common postoperative complications, as well as venous catheters for fluid administration. This text will be appreciated by veterinarians, technicians dealing with laboratory animals, and researchers designing animal and medical experiments.

  • The Equatorial Rain Forest

    A Geological History
    • 1st Edition
    • John R. Flenley
    • English
    The Equatorial Rain Forest: A Geological History presents the equatorial vegetation as a dynamic entity with varied and highly significant history. It also discusses other types of equatorial regions. It addresses the vegetational history from a palaeoecological viewpoint. Some of the topics covered in the book are the vegetation of equatorial regions; the prelude to the quaternary; the quaternary vegetation of equatorial Latin America; the quaternary vegetation of equatorial Africa; the cretaceous period; and the quaternary vegetation of equatorial indo-malesia. The value of vegetational history is fully covered. The effect of man on vegetation is discussed in detail. The text describes in depth the methods of studying vegetational history. The Paleocene, Eocene, and Oligocene epochs are presented completely. A chapter is devoted to the palynological evidence and synthesis. Another section focuses on the xeroseres, hydroseres and related successions. The book can provide useful information to botanists, geologists, students, and researchers.

  • Lectures on Bright's Disease

    • 1st Edition
    • Robert Saundby
    • English
    Lectures on Bright's Disease presents a clinical and pathological study of Bright's disease. This book provides a collection of lectures pertinent to Bright's disease, including febrile, obstructive, and lithemic nephritis. Organized into three sections encompassing 15 chapters, this book begins with an overview of the presence of an albuminous body in the urine that is coagulated by heat or precipitated by neutralization. This text then discusses the significant components of dropsy, which is the most striking symptom of Bright's disease. Other chapters consider the discovery of tube casts in the urine of patients suffering from diabetes, jaundice, and secondary congestions of the kidneys. This book discusses as well the alterations in the circulatory system as a clinical and pathological fact in Bright's disease. The final chapter deals with the principle of diagnosis and prognosis. This book is a valuable resource for pathologists, physicians, surgeons, clinicians, and medical students.

  • Annual Review of Chronopharmacology

    Volume 2
    • 1st Edition
    • A. Reinberg + 2 more
    • English
    Annual Review of Chronopharmacology, Volume 2 presents a scholarly means of rapidly communicating findings and developments in chronopharmacology, which is considered a quickly emerging field. This text first discusses aspects and statistical procedures in chronobiology and chronopharmacology. This book then explains circadian and circannual changes in nephrotoxic effects of heavy metals and antibiotics; chronotoxicology and chronopharmacology with emphasis on carcinostatic agents; and chronopharmacology of cardiovascular medications. The chronopharmacology and chronotherapy of asthma are also tackled. This book concludes by explaining the chronopharmacology of antidepressant drugs and of the inflammatory process. This publication will be invaluable to those interested in the field of chronopharmacology.

  • Biochemical and Molecular Aspects of Selected Cancers

    Volume 2
    • 2nd Edition
    • Thomas G. Pretlow II
    • English
    This two-volume work not only includes much of the newer molecular biology research but also important earlier research in this area essential for the comprehensive understanding of the biochemistry of neoplastic diseases. As such it will provide an invaluable source of information for the young investigator. Human cancers, not experimental models of cancer, are emphasized.

  • International Review of Connective Tissue Research

    Volume 9
    • 1st Edition
    • David A. Hall + 1 more
    • English
    International Review of Connective Tissue Research, Volume 9 provides information pertinent to the fundamental aspects of connective tissue research. This book reviews the methods involved in chromosome mapping of genes and their application to genes. Organized into six chapters, this volume begins with an overview of basement membranes updates. This text then examines the widespread use of the methods of immunofluorescence and immune electron microscopy. Other chapters consider the degradation of collagen in vivo that is of necessity under close biological control. This book discusses as well the nature and role of inhibitors of the collagenolytic enzymes in normal and pathological conditions. The final chapter emphasizes that in addition to the multiplicity of functions of connective tissue in various organs, the formation of this tissue is the major mechanism of the repair of damaged tissues in species that have lost the power of regeneration. This book is a valuable resource for biochemists.

  • Molecular Biology of Plants

    • 1st Edition
    • Irwin Rubenstein + 2 more
    • English
    Molecular Biology of Plants presents the formal scientific presentations delivered on the symposium on plant molecular biology, held at the University of Minnesota in 1976. The topics in this book are organized around the central dogma of molecular biology. Section I describes the organization and replication of DNA in plant chromosomes, including chloroplast genomes; Section II discusses molecular aspects of transcription and translation, ribosomal RNA gene systems and hormonal control of protein synthesis. Section III examines plant viruses and bacterial agents, in particular the crown gall system, viroids, and the replication of plant RNA viruses. Each of these specific topics contributes to an integrated knowledge of plant molecular biology. The book will be of interest to geneticists, cell biologists, plant breeders, plant physiologists, plant pathologists, and biochemists.

  • Cisplatin

    Current Status and New Developments
    • 1st Edition
    • Archie W. Prestayko
    • English
    Cisplatin: Current Status and New Developments is a collection of papers presented at a symposium sponsored by the University of Alabama in Birmingham Comprehensive Cancer Center and the Bristol Laboratories in Syracuse, ?ew York, and held on September 27-28, 1979, in Atlanta, Georgia. The symposium provided a forum for assessing developments with regards to cisplatin as an anticancer drug, with emphasis on its clinical application in a wide variety of adult and pediatric malignancies as well as the mechanism by which the drug appears to cause tumor cell death. Comprised of 39 chapters, this book begins with a preclinical overview of cisplatin, focusing on its mechanism of action, pharmacology, antitumor activity, analogs, and toxicity. The discussion then turns to the effects of cisplatin on DNA and the possible relationships to cytotoxicity and mutagenicity in mammalian cells; lethal activity of platinum compounds in combination with pyrimidine derivatives; and ultrastructural effects of cisplatin. Subsequent chapters focus on the rationale of combination chemotherapy; toxic side effects of platinum analogs; radiopharmacokinetic... of cisplatin; and the use of cisplatin for the treatment of malignancies such as ovarian cancer and advanced adenocarcinoma of the prostate. This monograph will be useful to oncologists and pharmacologists.

  • Toxicology of Chemical Mixtures

    Case Studies, Mechanisms, and Novel Approaches
    • 1st Edition
    • Raymond S.H. Yang
    • English
    Although toxicologic studies in the laboratory often focus on a single chemical, in the larger world, mixtures of chemicals are routinely encountered. Toxicology of Chemical Mixtures examines the mechanisms of interactions and health effects stemming from chemical mixtures in the environment. Toxicologists, pharmacologists, environmental scientists, and professionals involved in environmental clean-ups will benefit from its content.Emphasis is on low-level, long-term exposure.

  • Metabolic Diseases in Farm Animals

    • 1st Edition
    • Jack M. Payne
    • English
    Metabolic Diseases in Farm Animals discusses metabolic diseases in farm livestock, focusing on four clinical syndromes—parturient hypocalcaemia, hypomagnesaemia, ketosis, and bloat. This book discusses metabolic disorders associated with water, calcium, magnesium, sodium, potassium, nitrogen, and phosphorus. The parturient paresis, which causes considerable metabolic stress and disrupts the daily pattern of feeding and digestion of dairy cows is also elaborated. This text covers the changes in mineral metabolism at parturition; factors predisposing dairy cows to parturient paresis; cause of paresis in milk fever; and downer syndrome in dairy cows. The complexity of energy metabolism and its associated disorders are likewise described. This publication is a good source for veterinarians and livestock farmers concerned with metabolic diseases in farm animals.

  • Neurosciences Research

    Volume 3
    • 1st Edition
    • S Ehrenpreis + 1 more
    • English
    Neurosciences Research, Volume 3 covers research problems concerned with the central nervous system. The book discusses the transport processes at the brain cell; the life history of the microglial cell; and studies on the choroid plexus. The text also describes the role of the cerebral peduncle in movements, as well as the pathobiological aspects of the action of tetanal toxin in the nervous system and skeletal muscle. Neuroscientists, neurochemists, and neuropathologists will find book useful.

  • Trophic Regulation of the Basal Ganglia

    Focus on Dopamine Neurons
    • 1st Edition
    • K. Fuxe + 2 more
    • English
    Trophic Regulation of the Basal Ganglia: Focus on Dopamine Neurons examines neurotransmitters. The book first discusses the role of fibroblast growth factor-2 (FGF-2) and ganglioside GM1 and the trophic regulation of the basal ganglia. Biochemical and histochemical studies on the cellular localization of FGF-2; mapping of FGF-2 and its receptors in the basal ganglia postnatally and adulthood; and mapping of the ganglioside GM1 distribution in the basal ganglia are presented. The text also explains glucocorticoid and estrogen effects on the nigrostriatal and mesolimbic dopaminergic systems; factors associated to dopaminergic cell death in Parkinson's disease; and compensatory mechanisms at dopamine D-2 receptors. The book also describes the effects of brain-derived neurotrophic factor on injured dopaminergic neurons; role of gangliosides and trophic factors in brain repair; and features of the trophic action of polyamines. The text also underscores the presence of interleukin-1 in the central nervous system; neuropeptides synthesis in astrocytes; and astrocytic kynurenines as modulators of dopaminergic function in the rat basal ganglia. The selection is a good source of information for readers wanting to study neurotransmitters.

  • Essays in Toxicology

    Volume 5
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 5 covers essays in toxicology. The book presents essays on nitrosamines; a laboratory model ecosystem to evaluate compounds producing biological magnification; and the metabolism of DDT in human. The text also includes essays on the toxins of Clostridium botulinum; the use of breath analysis in clinical toxicology; and the biochemical toxicology of methanol. Toxicologists, biochemists, microbiologists, pharmacologists, and people involved in the research of toxicology will find the book invaluable.

  • Pathobiology of the Endothelial Cell

    • 1st Edition
    • Hymie L. Nossel + 1 more
    • English
    Pathobiology of the Endothelial Cell presents the proceedings of the symposium on the "Pathobiology of the Endothelial Cell" held at Arden House, on the Harriman Campus of Columbia University on June 5-7, 1981. The book discusses the endothelial growth regulation; the stimulation of vascular cell growth by macrophage products; and the control of proliferation and differentiation of endothelial cells. The text also describes vessel wall growth control; the implications of angiogenesis in vitro for tumor biology; and the interactions and activation of coagulation proteases. Platelet adhesion and fibrinogen proteolysis; endothelial protein synthesis; prostaglandins, and endothelial cell-cell interactions are also considered. The book further tackles topics on vascular pathobiology. Biologists, pathologists, biochemists, hematologists, oncologists, immunologists, and microbiologists will find the text invaluable.

  • Muscle Function Testing

    • 1st Edition
    • Vladimír Janda
    • English
    Muscle Function Testing provides information pertinent to the muscle functions. This book evaluates the method of examination that provides information about the strength of individual muscles or muscle groups that form a functional unit. Organized into three sections encompassing four parts, this book begins with an overview of the size, extent, and progress of peripheral nerve lesions. This text then discusses the nature of the simple movement pattern seen in muscle function testing. Other chapters consider the conditions for analytical physiotherapy and determination of the work capacity of the part of the body being tested. This book discusses as well the possible errors and mistakes that might occur during testing and might decrease the validity of the assessment. The final chapter deals with the demand for a better and a more rational method to therapeutic exercise. This book is a valuable resource for physiotherapists, orthopedic surgeons, physiologists, neurologists, and rheumatologists.

  • Frontiers in Colorectal Disease

    St. Mark's 150th Anniversary International Conference
    • 1st Edition
    • R. C. G. Russell + 1 more
    • English
    Frontiers in Colorectal Disease presents a compilation of articles from the international conference titled ‘Frontiers in Colorectal Disease’. It discusses the aspects of functional disorders, neoplastic disease and inflammatory bowel disease. It addresses the practical management of a variety of disorders of the colon, rectum, and anus. Some of the topics covered in the book are the basis of functional intestinal symptoms; nervous control of the gut; physiological reactions of the gastrointestinal tract to stress; visceral pain; mechanisms of flatulence and diarrhoea; pathophysiology of constipation; Arbuthnot Lane’s disease; and megacolon in adults. The results of surgical treatment of constipation are fully covered. The anorectal incontinence of electrophysiological tests is discussed in detail. The text describes in depth the risk factors in childbirth causing damage to the pelvic floor innervation. A retrospective study of the results of post-anal repair is presented completely. A chapter is devoted to the gracilis muscle transposition for anal incontinence. Another section focuses on the magnitude of risk for cancer in patients with colorectal adenomas. The book can provide useful information to doctors, surgeons, students, and researchers.

  • Effects of Gaseous Air Pollution in Agriculture and Horticulture

    • 1st Edition
    • M. H. Unsworth + 1 more
    • English
    Effects of Gaseous Air Pollution in Agriculture and Horticulture focuses on the impact of air pollution on agriculture and horticulture. This book discusses the existence of significant concentrations of gaseous pollutants in several agricultural regions of industrialized countries, which is facilitated by improved instrumentation and monitoring networks. Organized into six parts encompassing 49 chapters, this book begins with an overview of the two aspects of distribution of gas pollutants. This text then considers a technique for estimation of dose from measurements of gas concentration and stomatal conductance. Other chapters provide examples of monitoring of air-pollution effects on plants, with emphasis on both the concentrations and effects of air pollutants as they complement each other. This book discusses as well the formation and mechanism of action of nitrogen oxides. The final chapter deals with the peroxidation of membrane lipids. This book is a valuable resource for agriculturists, horticulturists, and scientists.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 5
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the utilization of operational schemes for analog synthesis in drug design; the design of enzyme inhibitors (transition state analogs); and the significance of structure-absorption... relationships for drug design. The text describes the role of charge-transfer processes in the action of bioactive materials, as well as the approaches to the rational combination of antimetabolites for cancer chemotherapy. The physicochemical, quantum chemical, and other theoretical techniques for the understanding of the mechanism of action of central nervous system (CNS) agents, such as psychoactive drugs, narcotics, and narcotic antagonists and anesthetics, are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

  • The Physical Foundation of Biology

    an Analytical Study
    • 1st Edition
    • Walter M. Elsasser
    • English
    The Physical Foundation of Biology: An Analytical Study offers a detailed account of the relationship between physics and biology. The discussion is based on a threefold development in theoretical science: the theory of automata (often designated as computers); the theory of information (mainly developed in communication engineering); and the theory of microscopic measurement in the atomic and molecular domain (based largely on quantum mechanics). This book is comprised of five chapters and begins with an overview of the physical foundation of biology, paying particular attention to preformationism and the theory of epigenesis. The first chapter explores feedback and control by comparing the control apparatus of a more differentiated organism, the nervous system, with the corresponding achievements of electronic engineering. The reader is then introduced to the theory of information, focusing on the idea that certain quantitative aspects of the information content of messages can be separated from the specific physical features of the device sending the message. The following chapters deal with the importance of storage or memory devices for a complex functional mechanism; the compatibility of biotonic laws with the ordinary laws of physics; and physical interpretation of the theory of microscopic processes. This monograph will be of interest to physicists, biologists, and chemists.

  • Protein Contribution of Feedstuffs for Ruminants

    Application to Feed Formulation
    • 1st Edition
    • E.L. Miller + 2 more
    • English
    Protein Contribution of Feedstuffs for Ruminants: Application to Feed Formulation covers papers about the findings and knowledge on the ""Evaluation of the Protein Contribution of Feedstuffs for Ruminant"". The book presents papers about the recent advances in the knowledge of protein evaluation for ruminants; similarities and differences between rumen fermentation and postruminal utilization; and methods of assessing proteins for ruminants. The text also covers papers about protected proteins and amino acids for ruminants; validation and application of principles of protein evaluation for ruminants; practical feeding trials in Norway; and protein-energy interrelationships for growing and for lactating cattle. A report of co-ordinated trials carried out on commercial farms in the UK is also presented in the book. The text will be invaluable to feed compounders, research workers, advisors, farmers and agricultural students.

  • International Review of Connective Tissue Research

    Volume 6
    • 1st Edition
    • David A. Hall + 1 more
    • English
    International Review of Connective Tissue Research, Volume 6 presents the relationship between structure and function in connective tissue. This book deals with articular cartilage, a connective tissue that depends for its function on the integrity of its surface. Organized into six chapters, this volume begins with an overview of the structure, biology, chemistry, and biochemistry of collagen. This text then summarizes the data on the construction and application of collagen products to medicine and surgery. Other chapters consider the characteristic of the amino acid composition of basement membranes and the structural features of the synovial joint. This book discusses as well the functional properties of collagenous tissues with emphasis on their behavior when internal or external mechanical stresses are applied. The final chapter deals with the structure of fresh connective tissue based on conventional histological procedures such as dehydration, fixation, embedding, and staining. This book is a valuable resource for biochemists, rheologists, and physicists.

  • Clinical Pharmacology in Obstetrics

    • 1st Edition
    • Peter Lewis
    • English
    Clinical Pharmacology in Obstetrics presents an extensive examination of drug usage in pregnancy. It discusses the principles behind the adverse effects of drugs on the fetus. It addresses studies in the drug treatment of heart disease in pregnancy. Some of the topics covered in the book are the examination of pharmacokinetics in pregnancy; analgesia intake of pregnant women; drug treatment of gastrointestinal disorders; antibiotics and antimicrobial chemotherapy; anemia and hematinics of pregnant women, use of cytotoxic drugs; and treatment of threatened and recurrent abortion. The definition and description of antihypertensive drugs, therapy for asthma, and tocolytic therapy for pretern labor are fully covered. An in-depth account of the prophylactic treatment of idiopathic respiratory distress syndrome is provided. The drug treatment of thyroid and adrenal disease are completely presented. A chapter is devoted to description and effect of perinatal drugs on new born baby. Another section focuses on the treatment of renal disease. The book can provide useful information to obstetricians, doctors, students, and researchers.

  • Current Approaches to Occupational Health

    Volume 2
    • 1st Edition
    • A. Ward Gardner
    • English
    Current Approaches to Occupational Health 2 is a compilation of articles that review the progress in the fields of occupational health, occupational medicine, and occupational hygiene. The book presents industry reviews of the rubber, coal mining, agriculture, and diving industries; occupational health problems; and toxicology, epidemiology, hazard management, work, education in occupational medicine, and health education at work. Occupational health professionals, physicians, and students will find the book invaluable.

  • Bacterial Endotoxins

    A Comprehensive Treatise
    • 1st Edition
    • George Weinbaum + 2 more
    • English
    Microbial Toxins, Volume IV: Bacterial Endotoxins covers a general introduction of bacterial endotoxins, as well as research concerning structure (both morphological and physical), chemistry, immunology, biosynthesis, and genetics of bacterial endotoxins. The book describes the general characteristics of bacterial endotoxins; the anatomy and chemistry of Gram-negative cell envelopes; and the physical structure of bacterial lipopolysaccharides. The text also discusses the isolation and chemical and immunological characterization of bacterial lipopolysaccharides; the chemistry of the unique carbohydrates of bacterial lipopolysaccharides; and the relation of bacteriophage attachment to lipopolysaccharide structure. The chemical and biological heterogeneity of endotoxins, as well as the biosynthesis of the core region of lipopolysaccharide are also considered. The book further tackles the biosynthesis of O-antigens and the genetic aspects of biosynthesis and structure of Salmonella lipopolysaccharide. Microbiologists, biochemists, bacteriologists, immunologists, and people involved in biochemical research will find the book useful.

  • Feeding of Non-ruminant Livestock

    • 1st Edition
    • Julian Wiseman
    • English
    Feeding of Non-Ruminant Livestock focuses on the nutrition of non-ruminant livestock. The book first discusses the feeding of non-ruminants, including regulation of feed intake and intake requirements and recommendations. The text highlights the energy value of feeds for non-ruminants; protein, vitamin, mineral, and nutrition of non-ruminants; and nutrition of rabbits. The book also underscores the nutrition of growing and breeding pigs, including gilts, boars, and sows. The text describes the nutrition of rapidly growing broilers. Presentation of diets and choice of energy level; proteins and amino acids; characteristics of production system; and mineral, vitamins, and additives are considered. The book also discusses the nutrition of laying hens and turkeys. Nutrition of rearing pullets; nutrition of hens during lay; meat turkeys; and nutrition of breeder turkeys during rearing are described. The text also highlights the nutrition of ducks, Japanese quails, and roasting geese. The book is a good source of information for readers wanting to study the nutrition demands of non-ruminant livestock.

  • Basic Pharmacology

    • 2nd Edition
    • R W Foster
    • English
    Basic Pharmacology, Second Edition, similar to the first edition, talks about the relationship between the human body and therapeutic drugs. A large part of this book discusses the nervous system and the way certain drugs operate and affect it. The first part of this book covers the importance of having a firm understanding of the organ system, especially the nervous system. Understanding the systems is the initial step in learning how a drug affects the body, both internally and externally. This book also clarifies that a drug's impact occurs when it comes in contact with a chemical component of the body (enzymes, hormones, membranes, etc.). The next sections of this book discuss miscellaneous topics of the human anatomy, such as the brain, eyes, lungs, and various muscles. This edition also explains how a drug acts on each of those body parts. This book serves as a great reference to students affiliated in the anatomy, biology, pharmacy, and related fields.

  • Steroid Hormone Regulation of the Brain

    Proceedings of an International Symposium Held at the Wenner-Gren Center, Stockholm, 27-28 October 1980
    • 1st Edition
    • Kjell Fuxe + 2 more
    • English
    Steroid Hormone Regulation of the Brain focuses on the advancement of knowledge of the properties of brain steroid receptors and steroid target nerve cells, including the actions of gonadal steroids, adrenocortical steroids, and androgenic steroids on the brain. The selection features the work of authors who have inspiringly conducted extensive studies on the action of steroid hormones. The book starts with discussions that point out that steroid hormones not only function through intracellular steroid receptors, but possibly through steroid membrane actions as well. Studies to support this claim are presented. As to the action of steroid hormones on presynaptic transmitter mechanisms, the book suggests that adrenocortical and gonadal steroids can create alterations in noradrenaline, adrenaline, and dopamine levels and turnover within the hypothalamus and preoptic area. The effects of catecholestrogens on the brain are also elaborated. A contribution to this paper stresses that estrogens have antidopaminergic action in the extrapyramidal system. This idea is identified through a series of behavioral experiments and measurements of the levels of striatal acetylcholine. This selection is recommended to scientists interested in studying the effect of hormones on the brain.

  • Essays in Toxicology

    Volume 6
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 6 approaches toxicology by very different routes; two essays with materials (plastics and tobacco alkaloids), one deals with the effects of abnormal pressure, one considers the biochemistry of the lung, and one discusses poison control centers and other mechanisms for limiting the injury done by toxic materials. The book presents essays on the topological problems and untoward effects from plastic devices used in medical applications; the metabolism of tobacco alkaloids; and poisons control center. The text also includes essays on the toxicology of hypobaric and hyperbaric environments; as well as the exploitable biochemical approaches for the evaluation of toxic lung damage. Biochemists, physical chemists, neurophysiologists, epidemiologists, and social scientists will find the book invaluable.

  • Contributions to Contemporary Neurology

    A Tribute to Joseph Michael Foley
    • 1st Edition
    • Robert B. Daroff + 1 more
    • English
    Contributions to Contemporary Neurology features articles presented at the scientific meeting at the March 1986 gala evening affair held in Cleveland, Ohio in honor of neurologist Joseph Michael Foley's seventieth birthday and his impending transition to Professor Emeritus at Case Western University. This book is organized into 20 chapters written by 41 contributors. It starts with the biography of Foley and ends with his curriculum vitae. In between the biographies and curriculum vitae are basic and clinical articles written by professionals closely associated with Foley throughout his illustrious career. This book will be of interest to those interested in learning about the life and career of neurologist Joseph Michael Foley.

  • Surtsey

    Evolution of Life on a Volcanic Island
    • 1st Edition
    • Sturla Fridriksson
    • English
    Surtsey: Evolution of Life on a Volcanic Island focuses on the origin of life in the island of Surtsey. The book first offers information on the Surtsey Research Society, conservation measures, and scientists that comprise the Surtsey research team. The text then focuses on the submarine eruptions off the coasts of Iceland, the flow of lava, and the formation and disappearance of islets. The book also describes the landscape that came about after the eruption. The tephra cones of the Surtur I and II craters, lava, coastal plains, and thermal areas are discussed. The text also underscores the ecological aspects of the eruption. The Icelandic biota and ecological studies on the island are discussed. The text also traces the origin of life in the island, including the dispersal of seeds by birds and “Mermaids purses.“ The text also underscores the origin of marine algae and marine fauna on the island. The book then emphasizes the presence of bacteria, molds, lichens, mosses, terrestrial animals, birds, and vascular plants in the island. The text also examines the outer Westman Islands. Topographical features, method of research, plant communities, and vegetation of the smaller islands are described. The book also notes the vegetation of Heimaey and the effects of insular eruptions on the southern coast of Iceland. The text is a good source of reference for readers wanting to study volcanic eruptions.

  • Recent Advances in Animal Nutrition

    • 1st Edition
    • P. C. Garnsworthy + 2 more
    • English
    Recent Advances in Animal Nutrition: 1992 is an annual review of the changes and updates in the field of animal nutrition, especially progresses in the study of feeds. The book is divided into four parts. Part I discusses topics related to nutrition in non-ruminant animals, while Part II covers ruminant nutrition. Part III tackles studies about general nutrition such as the use of growth promoters in animal feeds and predicting the response to variation and diet, and Part IV deals with feed compounding and its effects. The text is recommended for agriculturists, zoologists, and those involved in the development and manufacture of feeds who would like to know more about the nutrition of agriculturally important animals.

  • Aspects of the Origin of Life

    International Series of Monographs on Pure and Applied Biology
    • 1st Edition
    • M. Florkin
    • English
    Modern Trends in Physiological Sciences, Volume 6: Aspects of the Origin of Life presents the possible ways of the chemical evolution of the Earth's surface before the origination of life. This book examines the evolutionary aspects of the biochemistry of cells and organisms. Organized into 20 chapters, this volume begins with an overview of the conditions that characterized the physical state of the Earth during the earliest periods following its formation and development. This text then examines the content of elementary oxygen as the most remarkable aspect of the Earth's atmosphere. Other chapters consider the fundamental propositions concerning the biosphere, which is regarded as important to the geochemical processes of the Earth. This book discusses as well the history of the whole substance of Earth, which determines how far abiogenic synthesis could proceed and what was the state of the Earth when life came into being. Biochemists and scientists will find this book useful.

  • Spinal Degenerative Disease

    • 1st Edition
    • R. S. Maurice-Williams
    • English
    Spinal Degenerative Disease aims to provide a guide to the subject of spinal degenerative disease in all its aspects and to provide a balanced account of the more controversial parts of this field. It was written to fill the lack of books that deal with the degenerative disease of the vertebral column. This book is organized into 14 chapters that attempt to cover not only the pathology, clinical features, and treatment of spinal degenerative disease but also some relevant topics such as radiological techniques used in spinal investigation and the relationship between spinal arachnoiditis and degenerative disease. The book also discusses the relevant aspects of normal spinal physiology and anatomy and the differential diagnosis of spinal pain and sciatica. It also provides case histories to illustrate various points. This book will be of interest to students, medical professionals, and others interested in understanding the pathology and treatment of spinal degenerative disease.

  • Comprehensive Insect Physiology, Volume 4

    Regulation: Digestion, Nutrition, Excretion
    • 1st Edition
    • G. A. Kerkut
    • English
    In this volume, seven of the chapters deal with feeding and diet, which is reasonable since insects consume an estimated l5-20% of all the world's planted crops. Many insects even have a specialized larval feeding stage that usually occupies a different ecological niche to the adult and so does not compete for the adult's food stock. Other chapters describe the means by which insects maintain their water balance, nitrogen balance and temperature balance under a range of conditions. These involve regulation by hormonal and behavioural systems that are also described here. The l4 chapters are all extensively illustrated and referenced and therefore provide excellent summaries of current knowledge. They will be of great value to entomologists, zoologists and biologists in general.

  • Schering Workshop on Steroid Hormone 'Receptors', Berlin, December 7 to 9, 1970

    Advances in the Biosciences
    • 1st Edition
    • Gerhard Raspé
    • English
    Advances in the Biosciences 7: Schering Workshop on Steroid Hormone ""Receptors,"" Berlin, December 7 to 9, 1970 is a collection of papers presented at the Schering Workshop on Steroid Hormone ""Receptors,"" held in Berlin, Germany, on December 7-9, 1970. Contributors review research findings concerning steroid hormone receptors and cover topics organized around receptors of estrogen, androgen, progesterone, aldosterone, and corticosteroids. This book is comprised of 20 chapters and begins by analyzing the concentration of the estrogen binding protein in the rat uterus in three stages of uterine development, followed by a discussion on estradiol binding in mammalian tissues. The next section explores androgen receptors and includes chapters dealing with the specific binding of steroid-receptor complexes to DNA as well as the effects of androgen receptors on rat and human prostate. Subsequent chapters discuss the action of progesterone, aldosterone, and corticosteroid receptors. This monograph will be of interest to biochemists, biologists, and physiologists.

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