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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Neurotransmitter Transporters

    • 1st Edition
    • Volume 296
    • John N. Abelson + 1 more
    • English
    General Description of the Series:Neurotransmit... Transporters focuses on biochemical, electrophysiological... pharmacological, molecular, and cell biological approaches used to study neurotransmitter transport systems. The articles provide detailed descriptions of procedures that should enable the reader to understand how they are accomplished and to repeat or adapt them for their own experimental needs. This book is the first to focus on methods that have been the basis for the rapid development of this area.General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Animal Cognition in Nature

    The Convergence of Psychology and Biology in Laboratory and Field
    • 1st Edition
    • Russell P. Balda + 2 more
    • English
    In this book, the editors bring together results from studies on all kinds of animals to show how thinking on many behaviors as truly cognitive processes can help us to understand the biology involved. Taking ideas and observations from the while range of research into animal behavior leads to unexpected and stimulating ideas. A space is created where the work of field ecologists, evolutionary ecologists and experimental psychologists can interact and contribute to a greater understanding of complex animal behavior, and to the development of a new and coherent field of study.

  • Quantitative Functional Brain Imaging with Positron Emission Tomography

    • 1st Edition
    • Richard E. Carson + 2 more
    • English
    This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain.

  • Advances in Genetics

    • 1st Edition
    • Volume 38
    • English
    This volume of Advances in Genetics furthers the serial's goal of presenting topics of interest to both human and molecular geneticists. Topics of interest in this volume include:Expression patterns of regulatory genes and the role they play in developmentHereditar... ataxias and specific disease states where the genetic defect has been identifiedMinute genes, their mutations, and their molecular function in DrosophilaThe genetics and molecular biology of rhythm mutants and clock moleculesDouble strand breaks in DNA and their repair mechanisms

  • Human Aggression

    Theories, Research, and Implications for Social Policy
    • 1st Edition
    • Russell G. Geen + 1 more
    • English
    For centuries, scholars have debated the causes of aggression and the means to reduce its occurrence. Human Aggression brings together internationally recognized experts discussing the most current psychological research on the causes and prevention of aggression. Scholars, policy makers, practitioners, and those generally concerned with the growing issue of aggression find this a much needed reference work. Topics include how aggression is related to the usage of drugs, how temperature affects aggression, the effect of the mass media on aggression, violence by men against women, and the treatment of anger/aggression in clinical settings. The book also provides a comprehensive review of theory and methodology in the study of aggression.

  • Handbook of the Aging Brain

    • 1st Edition
    • Eugenia Wang + 1 more
    • English
    Handbook of the Aging Brain brings together diverse scientific disciplines to cover the most recent research findings in an easy-to-read summary. Scientists and clinicians will find a wide spectrum of subjects including gerontology, neurology, psychology, molecular biology, and cellular biology. The book includes general chapters on the neuroanatomy and neurobiology of the aging brain, and moves on to discussion of specifics including signal transduction, cell death, and specific cellular and neurological changes associated with dementia, Alzheimer's and Parkinson's Disease. Other chapters discuss the affect of aging on learning and memory, language, and cognition.

  • Molecular & Cellular Mechanisms of Neurotransmitter Release

    • 1st Edition
    • Volume 29
    • English
    This volume reviews recent findings on the regulation of exocytotic release of neurotransmitters from nerve terminals. Leading international investigators examine the properties and composition of the vesicles that store neurotransmitters and the molecular and cellular mechanisms that cause a vesicle to release transmitters in response to a nerve impulse.Coverage includes detailed analyses of quantal release of transmitters in the central and peripheral nervous systems. These studies shed new light on the questions of whether different transmitters are released together in fixed amounts and proportions, and whether and why effectors respond to such "transmitter quanta" in a quantal fashion. The book also highlights the relevance of research on neurotransmitter release to the study of various forms of synaptic plasticity, including higher functions such as learning and memory.

  • Eye Guidance in Reading and Scene Perception

    • 1st Edition
    • G. Underwood
    • English
    The distinguished contributors to this volume have been set the problem of describing how we know where to move our eyes. There is a great deal of current interest in the use of eye movement recordings to investigate various mental processes. The common theme is that variations in eye movements indicate variations in the processing of what is being perceived, whether in reading, driving or scene perception. However, a number of problems of interpretation are now emerging, and this edited volume sets out to address these problems. The book investigates controversies concerning the variations in eye movements associated with reading ability, concerning the extent to which text is used by the guidance mechanism while reading, concerning the relationship between eye movements and the control of other body movements, the relationship between what is inspected and what is perceived, and concerning the role of visual control attention in the acquisition of complex perceptual-motor skills, in addition to the nature of the guidance mechanism itself.The origins of the volume are in discussions held at a meeting of the European Society for Cognitive Psychology (ESCOP) that was held in Wurzburg in September 1996. The discussions concerned the landing effect in reading, an effect, that if substantiated, would provide evidence of the use of parafoveal information in eye guidance, and these discussions were explored in more detail at a small meeting in Chamonix, in February 1997. Many of the contributors to this volume were present at the meeting, but the arguments were not resolved in Chamonix either. Other leaders in the field were invited to contribute to the discussion, and this volume is the product. The argument remains unresolved, but the problem is certainly clearer.

  • Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1st Edition
    • Volume 38
    • English
    @from:General Description of the SeriesThe Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work. @from:General Description of the VolumeVolume 38 covers emotional memory, metacomprehension of text, and intertemporal choice.

  • Neural Aspects of Tactile Sensation

    • 1st Edition
    • Volume 127
    • J.W. Morley
    • English
    The world within reach is characterised to a large extent by our ability to sense objects through touch. Research into the sensation of touch has a long history. However, it is only relatively recently that significant advances have been made in understanding how information about objects we touch is represented in both the peripheral and central divisions of the nervous systems. This volume draws together the increasing body of knowledge regarding the mechanisms underlying tactile sensation and how they relate to tactile perception.Individua... chapters address; the response of mechanoreceptors to stimuli (including movement and shape), the role of the somatosensory cortex in processing tactile information, the psychophysics and neurophysiology of the detection and categorisation of somesthetic stimuli, perceptual constancy, recent findings in regard to short term and long term plasticity in the somatosensory cortex and the psychophysical correlates of this plasticity, and parallel versus serial information processing in the cortex.The authors look at past and current research, and comment on the direction of future investigation, relating findings from psychophysical studies of tactile behavior to our growing understanding of the underlying neural mechanisms.

  • Handbook of Developmental Neurotoxicology

    • 1st Edition
    • William Slikker Jr. + 1 more
    • English
    The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology.

  • Brain Function in Hot Environment

    • 1st Edition
    • Volume 115
    • H.S. Sharma + 1 more
    • English
    Although problems relating to hyperthermia and heat stroke are well known since biblical times, until now the influence of heat or hyperthermia on the central nervous system has not been well documented. This book is the first to describe in detail the influences of hyperthermia on the CNS using the modern technology which has developed in the last 50 years in neuroscience. Hyperthermia is a common feature during fever, radiotherapy of tumours and exercise in hot environment. Statistically, hyperthermia and/or heat stroke is currently recognised as the third largest killer in America after head and spinal trauma and heart failure. However, studies on the mechanisms of heat-induced death or damage to the CNS are still lacking. This book aims to define the probable mechanisms of brain damage in hyperthermia which could be responsible for death of victims. Rational therapeutic measures based on the experimental findings are also described.The most important new aspect of the CNS function in hyperthermia suggests that the basic mechanisms of cell injury appears to be quite similar in nature. The severity of cell injury depends chiefly on the magnitude of the primary insult. Thus, it appears that hyperthermic brain injury is similar to the situation of trauma, ischemia and infarction. Baring this in mind, this book describes suitable models for hyperthermic injury which could be highly relevant to the study of mechanisms of cell injury in the CNS and to test various neuroprotective agents which may be found useful in the treatment of various traumatic, ischemic or degenerative diseases.In general the book will increase our basic understanding of brain function in hot environment and increase our awareness regarding heat as an important factor influencing our brain function at a time when global warming is described as a potential hazard to the biological system.This book is a refereed collection of 24 chapters written by several eminent scientists from different disciplines involved in basic and applied research in the CNS from various parts of the globe. It is hoped that the new aspects of brain function in hot environment compiled in this volume will provide an up-to-date ready reference which may serve as a strong scientific stimulus to many workers in this emerging field of neuroscience. Stimulating the exploration of the subject with novel ideas and/or experimental and clinical approaches in the future.

  • Memory

    • 1st Edition
    • Elizabeth Ligon Bjork + 1 more
    • English
    Authored by the foremost researchers in cognitive psychology, the handbook Memory is an outstanding reference tool for all cognitive psychologists and interested professionals. Memory provides an excellent synopsis of the research and literature in this field, including comprehensive chapters on basic theory. The text discusses storage and access of information in both short-term and long-term memory; how we control, monitor, and enhance memory; individual differences in mnemonic ability; and the processes of retrieval and retention, including eye-witness testimony, and training and instruction.

  • Advances in the Study of Behavior

    Stress and Behavior
    • 1st Edition
    • Volume 27
    • English
    Advances in the Study of Behavior continues to serve scientists across a wide spectrum of disciplines. Focusing on new theories and research developments with respect to behavioral ecology, evolutionarybiology, and comparative psychology, these volumes foster cooperation and communication in these diverse fields.

  • The Other Side of the Error Term

    Aging and Development as Model Systems in Cognitive Neuroscience
    • 1st Edition
    • Volume 125
    • N. Raz
    • English
    It has been said more than once in psychology that one person's effect is another person's error term. By minimising and occasionally ignoring individual and group variability cognitive psychology has yieled many fine achievements. However, when investigators are working with special populations, the subjects, and the unique nature of the sample, come into focus and become the goal in itself. For developmental psychologists, gerontologists and psychopathologists, research progresses with an eye on their target populations of study. Yet every good study in any of these domains inevitably has another dimension. Whenever a study is designed to turn a spotlight on a special population, the light is also shed on the mainstream from which the target deviates.This book examines what we can learn about general and universal phenomena in cognition and its brain substrates from examining the odd, the rare, the transient, the exceptional and the abnormal.

  • System Theories and A Priori Aspects of Perception

    • 1st Edition
    • Volume 126
    • J.S. Jordan
    • English
    This book takes as a starting point, John Dewey's article, The Reflex Arc Concept in Psychology, in which Dewey was calling for, in short, the utilisation of systems theories within psychology, theories of behaviour that capture its nature as a vastly-complex dynamic coordination of nested coordinations. This line of research was neglected as American psychology migrated towards behaviourism, where perception came to be thought of as being both a neural response to an external stimulus and a mediating neural stimulus leading to, or causing a muscular response. As such, perception becomes a question of how it is the perceiver creates neural representations of the physical world. Gestalt psychology, on the other hand, focused on perception itself, utilising the term Phenomenological Field; a term that elegantly nests perception and the organism within their respective, as well as relative, levels of organisation. With the development of servo-mechanisms during the second world war, systems theory began to take on momentum within psychology, and then in the 1970s William T Powers brought the notion of servo-control to perception in his book, Behavior: The Control of Perception. Since then, scientists have come to see nature not as linear chain of contingent cause-effect relationships, but rather, as a non linear, unpredictable nesting of self referential, emergent coordinations, best described as Chaos theory. The implications for perception are astounding, while maintaining the double-aspect nature of perception espoused by the Gestalt psychologists. In short, system theories model perception within the context of a functioning organism, so that objects of experience come to be seen as scale-dependent, psychophysically-neu... phenomenological transformations of energy structures, the dynamics of which are the result of evolution, and therefore, a priori to the individual case. This a priori, homological unity among brain perception and world is revealed through the use of systems theories and represents the thrust of this book. All the authors are applying some sort of systems theory to the psychology of perception. However, unlike Dewey we have close to a century of technology we can bring to bear upon the issue. This book should be seen as a collection of such efforts.

  • International Review of Neurobiology

    • 1st Edition
    • Volume 42
    • English
    Volume 42 presents an in-depth review on Alzheimer's Disease as well as a look at several transcription factors.

  • Cerebral Asymmetries in Sensory and Perceptual Processing

    • 1st Edition
    • Volume 123
    • S. Christman
    • English
    The purpose of the book is to provide a comprehensive overview of hemispheric differences in sensory and perceptual processing. The first section of the book deals directly with the intra- and inter-hemispheric processing of spatial and temporal frequencies in the visual modality. The second section addresses the initial interaction between sensory and cognitive mechanisms, dealing with how the left and right cerebral hemispheres differ in their computation and representation of sensory information. The third section covers how attentional mechanisms modulate the nature of perceptual processing in the cerebral hemispheres. Section four consists of a single chapter which reviews evidence suggesting a functional linkage between upper and right visual field processing, on the one hand, and lower and left visual field processing on the other.

  • Measurement, Judgment, and Decision Making

    • 1st Edition
    • Michael H. Birnbaum
    • English
    Measurement, Judgment, and Decision Making provides an excellent introduction to measurement, which is one of the most basic issues of the science of psychology and the key to science. Written by leading researchers, the book covers measurement, psychophysical scaling, multidimensional scaling, stimulus categorization, and behavioral decision making. Each chapter provides a useful handbook summary and unlocks the door for a scholar who desires entry to that field. Any psychologist who manipulates an independent variable that affects a psychological construct or who uses a numerical dependent variable to measure a psychological construct will want to study this book.

  • Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1st Edition
    • Volume 37
    • English
    The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work.

  • The Cerebellum and Cognition

    • 1st Edition
    • Volume 41
    • English
    The Cerebellum and Cognition pulls together a preeminent group of authors. The cerebellum has been previously considered as a highly complex structure involved only with motor control. The cerebellum is essential to nonmotor functions, and recent research has revealed new medically important roles of the cerebellum and cognitive processes.

  • Perceptual learning

    Advances in Research and Theory
    • 1st Edition
    • Volume 36
    • English
    The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work.

  • Tasting and Smelling

    • 1st Edition
    • Gary K. Beauchamp + 1 more
    • English
    Tasting and Smelling presents a comprehensive overview to research on these two important modes of perception. The book offers a review of research findings on the biophysics, neurophysiology, and psychophysicsof both senses, as well as discussing the emotional component associated with taste and smell, and clinical disorders affecting each of these two senses. Tasting and Smelling answers how odors and flavors are perceived, why we have favorites, and what happens when our senses go awry. This book is of interest to the researcher in perception, cognition, or neurophysiology.

  • Developing Brain Behaviour

    The Role of Lipids in Infant Formula
    • 1st Edition
    • John Dobbing
    • English
    Certain long chain polyunsaturated fatty acids (LCPUFAs) are thought to be essential components of the nutrition of infants, including those prematurely born, in the sense that they cannot be synthesises by the immature organism and must therefore be supplied in the diet. Breast milk contains these substances, but many manufactured infant formulae do not.An absence of dietary LCPUFAs has been thought to affect the development of the brain and retina, possibly leading to abnormalties in cognitive and visual function. Considerable multidisciplinary research has been carried out to investigate this proposition. Diets free from LCPUFAs have been compared with supplemented formulae, or with breast milk.The conclusions from this research were critically examined by a group of leading paediatricians, nutritionists, experts in visual science and developmental behavioural scientists at a 'Dobbing Workshop' held in the United States in late February, 1997. Each of the Chapters was precirculated to the whole group, commented on before the Workshop, and then exhaustively discussed. The Chapters and Commentaries which are published here have therefore undergone a more extensive peer-review process than is usually the case.

  • Serotonin Receptors and their Ligands

    • 1st Edition
    • Volume 27
    • B. Olivier + 2 more
    • English
    An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin receptors or serotonin transporters either as agonists, partial agonists or antagonists.Structur... - affinity relationships and structure - activity relationships of agonists, partial agonists, and antagonists of 5-HT receptors and uptake sites, are discussed. Structure, sequence homology and the effect of site-directed mutations of 5-HT receptors and the reuptake site on the binding of ligands show the tremendous impact of molecular biology on medicinal chemistry research. Also discussed is the pharmacology and (potential) clinical applications of ligands for the 5-HT receptors and the reuptake site. By developing elegant techniques of cloning and expression of serotonin receptor subtypes, their mutants and chimeras, a unique opportunity was offered to study the binding mode of serotoninergic ligands to their receptors and transporters.The distribution, structure and homologies of serotonin receptor subtypes and the structure of the serotonin transporter are also taken into account.The (potential) therapeutic applications of ligands of the different subtypes are described.Altogether an excellent addition to the Pharmacochemical Library series.

  • Time and Behaviour

    Psychological and Neurobehavioural Analyses
    • 1st Edition
    • Volume 120
    • C.M. Bradshaw + 1 more
    • English
    That time is both a dimension of behaviour and a ubiquitous controlling variable in the lives of all living things has been well recognized for many years.The last decade has seen a burgeoning of interest in the quantitative analysis of timing behaviour, and progress during the last five or six years has been particularly impressive, with the publication of several major new theoretical contributions.There has also been considerable progress in behavioural methodology during the past decade. In the area of reinforcement schedules, for example, the venerable interresponse–time schedule, fixed–interval peak procedure and interval bisection task have been complemented by a 'second generation' of incisive instruments for analyzing timing behaviour.Another area of recent development is the analysis of the neurobiological substrate of timing behaviour. Several research groups are currently studying the involvement of various central neurotransmitter systems in the timing behaviour, and the ability of centrally acting drugs and discrete brain lesions to alter timing processes. Yet another recent development in timing research is the growing dialogue between two fields that have grown up separately, although, superficially at least, they seem to have much in common: the experimental analysis of 'interval timing', traditionally the province of experimental psychology, and behavioural chronobiology. The last few years have seen a growing interest in the comparative properties of the internal 'clocks' that regulate biobehavioural rhythms with time bases in the circadian range or longer, and those that are entailed in timing of intervals in the range of seconds or minutes.All these areas of research, and others, are represented in the chapters that make up this volume. This book will help to promote further interactions among researchers who hail from disparate disciplines, but who share a common interest in the temporal properties of behaviour.

  • Advances in Pharmacology

    • 1st Edition
    • Volume 39
    • English
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

  • The Cerebellum: From Structure to Control

    • 1st Edition
    • Volume 114
    • C.I. De Zeeuw + 2 more
    • English
    Many of the cerebellar scientists of the established generation have contributed substantially to the quality of this issue. In addition, the book is marked by chapters from the coming generations of scientists who will determine the direction of cerebellar research for the next century. As in other fields of neuroscience, this research will be dominated by molecular neurobiology and new functional imaging techniques. Altogether, the book is pluriform and unique in that it is multidisciplinary, in that it promotes different views on cerebellar function, and that it is being published on the verge of different era's dominated by different generations of cerebellar scientists. The wealth of new information and ideas contained in these important papers will stimulate even more intensive research in the twenty-first century leading to a greater understanding of cerebellar function(s).

  • Anomia

    Neuroanatomical and Cognitive Correlates
    • 1st Edition
    • Harold Goodglass + 1 more
    • English
    Anomia is the inability to access spoken names for objects, most often associated with the elderly or those with brain damage to the left hemisphere. Anomia offers the state-of-the-art review of disorders of naming, written by acknowledged experts from around the world, approached from both clinical and theoretical viewpoints. Goodglass, known around the world for his research in aphasia and speech pathology, edits this first book devoted exclusively to naming and its disorders. Wingfield is known for his classic studies of lexical processing in aphasic and normal speakers. The book includes comprehensive literature reviews, a summary of relevant research data, as well as astudy of recent advances in cognitive analysis and anatomic findings. Anomia is an immensely useful work for all those involved in the study of language, particularly those in cognitive neuroscience, neurology, speech pathology, and linguistics.

  • Atlas of the Human Brain

    • 1st Edition
    • Juergen K Mai + 2 more
    • English
    This unique atlas of the human brain correlates studies of post mortem tissue with the in situ, cross-sectional brain and MRIs of the same brain in situ with in vivo images from normal volunteers. This atlas contains a series of maps, each featuring different aspects of brain morphology and topography. The atlas is divided into two sections: the Topographic and Topometric Atlas and the Myeloarchitectonic Atlas. The Topographic and Topometric atlas presents the surface anatomy of the brain over a topometric grid, together with corresponding in situ sections of the entire head, placed on stereotaxic grids in order to emphasize the brain. The part of the atlas is further divided into three sections: the Horizontal, the Coronal, and the Sagittal. The Myeloarchitectonic atlas presents 69 myelin-stained sections cut perpendicular to the intercommissural line depicting mainly subcortical structures. Each plate has corresponding schematic diagrams defining position, extent, and relationship of nuclei and pathways of the forebrain and mesencephalon.

  • The Primate Nervous System, Part I

    • 1st Edition
    • Volume 13
    • Floyd E. Bloom + 2 more
    • English
    This volume is a new, timely and fitting extension to the Handbook of Chemical Neuroanatomy, focussing on the neurochemical circuitry of the primate brain. The book will compliment the growing efforts to apply the analytical strategies of chemical neuroanatomy to the primate brain.The goal of this volume is to develop a broad-based coverage of human and non-human primate chemical neuroanatomic details together within a volume in which details on transmitters and systems can be appreciated.The eight comprehensive chapters that comprise this volume deal with large global concepts and datasets which not only create an initial coverage of the entire primate neuraxis, but also capture useful points of information on the chemical neuranatomy of the primate nervous system.An excellent, informative book, and a welcome addition to the sparse literature in this field.

  • The Comprehensive Evaluation and Treatment of Epilepsy

    A Practical Guide
    • 1st Edition
    • Steven C. Schachter + 1 more
    • English
    Epilepsy is, after headache, the second most common neurological disorder. This book clarifies the many courses of action to take in treating patients with epilepsy. It presents current knowledge about seizures and epilepsy in a comprehensive, socially conscious, and clear manner. The editors have provided this information in a comprehensive, easy-to-use, and practical form. This short, simple pedagogical guide to the diagnosis and management of epilepsy is an important reference work for all medical schools, hospitals, clinics, and primary care centers.

  • Neuroscience LabFax

    • 1st Edition
    • English
    Neuroscience LabFax is a comprehensive collection of the most up-to-date methods and data available in neuroscience, addressing issues from the molecular and biophysical to the cellular and systems level of analysis. Complemented by excellent diagrams, the information is clearly presented and easily accessible. Neuroscience LabFax has a broad-based interdisciplinary focus, integrating methods and data from cellular and molecular neuroscience, biophysics and behavior. This volume covers electrophysical recording, neuronal cell culture, preparation of tissues for microscopy or analysis, and molecular biology and neurobiology techniques. Written by experts in the field, this text is essential for neuroscientists from all subdisciplines, for those new to the field as well as experienced researchers.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 26
    • English
    Advances in the Study of Behavior continues to serve scientists across a wide spectrum of disciplines. Focusing on new theories and research developments with respect to behavioral ecology, evolutionary biology, and comparative psychology, these volumes foster cooperation and communication in these diverse fields.

  • Excitatory Amino Acids

    Clinical Results with Antagonists
    • 1st Edition
    • Paul L. Herrling
    • English
    Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results of human testing of modulators of excitatory amino acid neurotransmitters.

  • An Introduction to the Psychology of Hearing

    • 4th Edition
    • Brian C.J. Moore
    • English
    Now available in a Fourth Edition, Introduction to the Psychology of Hearing is the leading textbook in the field of auditory perception--also known as psychoacoustics. The book emphasizes the mechanisms underlying auditory perception and carefully explains key concepts. There are many illustrations--a large portion of which were produced especially for the book. The Fourth Edition has been thoroughly updated, with more than 150 references to articles and books published since 1990.Introductory chapters describe the basic physical concepts needed to understand the nature of auditory stimuli and the physiology of the auditory system, concentrating on the peripheral auditory system and particularly the inner ear (the cochlea). Later chapters cover auditory object perception, and extensively discuss the auditory systems ability to analyze a complex mixture of sounds in order to derive percepts corresponding to the individual sound sources. Also covered are speech perception, the basic auditory processes underlying speech perception, practical applications such as hearing aids and cochlear implants, the psychoacoustics of high-fidelity sound reproduction, and concert hall acoustics. The book includes an extensive list of references, glossary, and subject index.

  • Cholinergic Mechanisms: From Molecular Biology to Clinical Significance

    • 1st Edition
    • Volume 109
    • J. Klein + 1 more
    • English
    This volume offers a comprehensive update and overview of the field of cholinergic transmission as presented by some thirty distinguished investigators who were recruited for their task from Germany, Great Britain, Canada, USA, Sweden, Israel, France and Italy. Exciting new discoveries, described in this volume, are due to recent methodological breakthroughs. These discoveries throw new light on many areas of cholinergic mechanisms.

  • Towards the Neurobiology of Chronic Pain

    • 1st Edition
    • Volume 110
    • G. Carli + 1 more
    • English
    This excellent volume provides a well-balanced review of activity-dependent modifications of synaptic efficacy which follow noxious events, and is based on the symposium "Towards the Neurobiology of Chronic Pain", organized in Siena, at the Certosa di Pontignano. The book will contribute to the continuing interest in understanding pain reinforcement by the brain. This emerging new concept can in turn be expected to have a great impact on the development of clinical paradigms of pain prevention and rehabilitation.

  • The Polymodal Receptor - A Gateway to Pathological Pain

    • 1st Edition
    • Volume 113
    • T. Kumazawa + 2 more
    • English
    This volume is derived from a celebration of the career of Professor Takao Kumazawa at Nagoya University and includes papers from investigators throughout the world whose contributions are dedicated to his honour. Topics range from current studies and reviews of the impact of modern molecular biology on the contemporary knowledge of polymodal receptors, to reflections related to the career and lifetime achievements of a pioneer neurophysiologist who has focused on relatively simple modal systems, especially those concerned with deep or visceral sensing mechanisms and their role in the broad behavioral spectrum constituting pain.

  • Chemical Factors in Neural Growth, Degeneration and Repair

    • 1st Edition
    • C. Bell
    • English
    This volume provides an up-to-date survey of current thinking concerning the actions of chemical factors in the regulation of neuronal behaviour under normal and pathological conditions. The book is divided into four sections, dealing with chemical factors involved with the formation of axon pathways, factors involved with neuronal survival and specialization during normal development, factors involved in normal maintenance and repair of adult neurons and, finally, factors that have been implicated as mediators of degenerative changes in neurological and neuropsychiatric disorders.

  • The Mouse Brain in Sterotaxic Coordinates

    • 1st Edition
    • Keith B.J. Franklin + 1 more
    • English
    The Mouse Brain in Stereotaxic Coordinates is the first atlas in more than 20 years to provide an up-do-date diagrammatic reference illustrating the coronal plates of the mouse brain. As in the renowned Academic Press publication, The Mouse Brain in Stereotaxic Coordinates, Second Edition, the stereotaxic accuracy of each section is ensured. The standard reference marks are repeated in each structure, and the atlas is sectioned with excellent symmetry. The large, easy-to-use format displays the sections alternately stained for Nissl substance and for acetylcholinestrase. Comprising 93 clearly reproduced images and corresponding diagrams, this atlas is a must reference in every lab.

  • Hypothalamic Integration of Circadian Rhythms

    • 1st Edition
    • Volume 111
    • R.M. Buijs + 4 more
    • English
    The International Summer School of Brain Research, on which this book is based, was organized by the Netherlands Institute for Brain research (NIBR), which has a rich history dating back to the beginning of the century.The focus of interest in this present volume of Progress in Brain Research are the few thousand neurons at the base of the hypothalamus that form the biological clock. Attention is focused on the mechanisms underlying the generation of circadian rhythmicity within our biological clock, which is still far from understood. Contributions originating from many disciplines give updates on the latest theories on the molecular and electrophysiological basis of the pacemaker mechanism, and the various approaches used in different species. Attention is also paid to the way the signal of the biological clock is transferred to the rest of the central nervous system. New data on the role of the suprachiasmatic nucleus and its impact on the functioning of the human being is presented. Altogether an excellent volume which will further the understanding of this elusive material.

  • International Review of Neurobiology

    • 1st Edition
    • Volume 39
    • English
    Since 1959, International Review of Neurobiology has been a well known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.

  • Neuroprotective Agents and Cerebral Ischaemia

    • 1st Edition
    • Volume 40
    • English
    Since 1959, International Review of Neurobiology has been a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes. Stroke is the third major cause of death in the western world, and recent data provide hope that treatments may soon be available. Written by world experts on the mechanisms involved in neurodegeneration, Neuroprotective Agents and Cerebral Ischaemia presents an up-to-date review of current research and developing therapies. This book is essential reading for all clinicians and researchers searching for neuroprotective drugs.

  • Extrageniculostriate Mechanisms Underlying Visually-Guided Orientation Behavior

    • 1st Edition
    • Volume 112
    • M. Norita + 2 more
    • English
    The last few years have seen a dramatic increase in the number of areas known to be involved in mammalian vision. It has also seen a far greater understanding of the importance of reciprocal connections, intrinsic connections, structure-specific modules and modules which span different structures, as well as the introduction of parallel processing models within the thalamocortical and corticocortical streams.The body of knowledge has become so vast, and is growing so rapidly, that periodic updates are essential even for experts in the field. This volume is based on a satellite meeting of an international group of researchers. It emphasizes the most current information regarding midbrain and extrastriate mechanisms underlying vision and visually-guided behavior. The book also places these data into the larger context of how interrelated components of the visual system function to produce coherent visual experiences and behavior. New research findings are presented that are unavailable elsewhere, as well as reviews and broad perspectives in which existing data from multiple sources are brought together in order to help understand the structure and function of extrageniculostriate visual areas.

  • Neural Development and Plasticity

    • 1st Edition
    • Volume 108
    • R.R. Mize + 1 more
    • English
    This Progress in Brain Research volume is the outgrowth of a symposium entitled "Neural Development and Plasticity" which was held in New Orleans, Louisiana. The reader will find substantial new information about the mechanisms underlying growth cone dynamics, about molecules involved in axon outgrowth and cell adhesion, the role of proteoglycans and glial factors in directing or confirming axons to their appropriate targets, and the role of myelin-associated growth inhibitors. The book will contribute new ideas and identifies new questions of primary importance to developmental neurobiology.

  • Neuropeptide Y and Drug Development

    • 1st Edition
    • Lars Grundemar + 1 more
    • English
    Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles. It is involved in the body energy balance and is one of the most potent stimuli of food intake known. NPY also acts to regulate central and peripheral autonomic functions. This book, written by academic and industrial experts in the field, links the most recent basic experimental knowledge about NPY and its receptors with areas of clinical importance. This book will be of interest to those working in all areas of research affected by NPY, such as food intake and energy homeostasis, cardiovascular regulation and G-protein-coupled receptors, as well as those interested in the development of drugs as NPY targets.

  • Stimulus Class Formation in Humans and Animals

    • 1st Edition
    • Volume 117
    • T.R. Zentall + 1 more
    • English
    Stimulus class formation has been studied independently by two groups of researchers. One group has come out of a learning theory approach, while the second has developed out of a behavior analytic tradition. The purpose of the present volume is to further establish the ties between these two research areas while allowing for differences in approach to the questions asked. The book is loosely organized around four themes. The first two sections deal with what constitutes functional and equivalence classes in animals and humans. In the third section, the authors attempt to identify stimulus control variables that contribute to the formation of equivalences classes. The last section deals with the complex issue of the role of verbal behavior in equivalence classes. The goal of the book is to provide the reader with a better understanding of the current state of research and theory in stimulus class formation. It is also hoped that it will stimulate research into how and under what conditions, stimulus classes can form.

  • Visual Attention and Cognition

    • 1st Edition
    • Volume 116
    • W.H. Zangemeister + 2 more
    • English
    The goal of this book is to put together some of the main interdisciplinary aspects that play a role in visual attention and cognition. The book is aimed at researchers and students with interdisciplinary interest. In the first chapter a general discussion of the influential scanpath theory and its implications for human and robot vision is presented. Subsequently, four characteristic aspects of the general theme are dealt with in topical chapters, each of which presents some of the different viewpoints of the various disciplines involved. They cover neuropsychology, clinical neuroscience, modeling, and applications. Each of the chapters opens with a synopsis tying together the individual contributions.

  • Pain and Touch

    • 1st Edition
    • Lawrence Kruger
    • English
    An explosion of advances in the area of tactile perception and pain led to the development of this comprehensive, state-of-the-art text on basic research and clinical practice. Equal parts psychology and neuroscience, Pain and Touch covers peripheral cutaneous tactile information processing, sensory mapping, tactile exploratory behavior, neurophysiology of nociception and nociceptors in pain research, clinical scaling methods for psychophysics of pain, and paincontrol, pathology, and therapeutics.

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