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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Neuromuscular Junction Disorders, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 36-2
    • Mazen M. Dimachkie + 1 more
    • English
    This issue of Neurologic Clinics, edited by Dr. Mazen M. Dimachkie and Dr. Richard J. Barohn, focuses on Neuromuscular Junction Disorders. Topics include--but are not limited to--History of myasthenia gravis and neuromuscular junction disorders; Practical immunology of the neuromuscular junction; Practical anatomy of the neuromuscular junction in health and disease; Generalized myasthenia gravis; Ocular myasthenia gravis; Diagnosis of myasthenia gravis; MuSK and myasthenia gravis due to other autoantibodies; Treatment of myasthenia gravis; Evidenced-based approach of thymectomy for myasthenia gravis; Myasthenia gravis and pregnancy; Congenital myasthenic syndromes; Botulism; Lambert-Eaton myasthenic syndrome; and Measuring clinical treatment response in myasthenia gravis.
  • Imaging of Salivary Glands, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 28-2
    • Ahmed Abdel Khalek Abdel Razek
    • English
    This issue of Neuroimaging Clinics of North America focuses on Imaging of Salivary Glands, and is edited by Dr. Ahmed Abdel Khalek Abdel Razek. Articles will include: Cross sectional imaging techniques and normal anatomy of the salivary glands; Imaging of benign salivary gland tumors; Imaging of cancer salivary glands; Imaging of Sjögren's syndrome and immunoglobulin g4-related disorder of salivary glands; Imaging of post treatment of salivary glands; Imaging of pediatric salivary glands; Imaging of submandibular and sublingual salivary glands; Scintigraphy and PET of salivary glands; Imaging of inflammatory disorders of salivary glands; Routine and advanced ultrasound of salivary glands; and more!
  • The Molecular and Cellular Basis of Neurodegenerative Diseases

    Underlying Mechanisms
    • 1st Edition
    • Michael S. Wolfe
    • English
    The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.
  • The Neurology of HIV Infection

    • 1st Edition
    • Volume 152
    • English
    The Neurology of HIV Infection covers all aspects of nervous system involvement and pathology in HIV-infected individuals. Specialists in this field cover epidemiology, global aspects, pathology and pathogenesis of nervous system disease in HIV-infection. All complications, including the pathology caused by HIV itself and all opportunistic infections of the nervous system are reviewed in detail. Both central nervous and peripheral nervous system complications, including neuropathies and myopathies, are discussed. Key chapters on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children complete this volume.
  • Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

    • 2nd Edition
    • Herbert B. Newton
    • English
    Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed.
  • Ischemic and Traumatic Brain and Spinal Cord Injuries

    Mechanisms and Potential Therapies
    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Ischemic and Traumatic Brain and Spinal Cord Injuries: Mechanisms and Potential Therapies presents readers with comprehensive and cutting-edge information on molecular mechanisms, including the signal transduction processes associated with neurodegeneration and neuroprotection in ischemic, spinal cord, severe and mild brain injuries. The book also covers the molecular mechanisms of drugs used for the treatment of neurotraumatic disease. Chapters are organized by molecular aspects and neuroprotective strategies by disease, including ischemic injury, spinal cord injury, traumatic brain injury, and chronic traumatic encephalopathy. The book integrates and consolidates knowledge on neurotraumatic diseases, with the hope of bringing forth more dramatic advances and developments, not only on molecular mechanisms, but also on the causes of, and treatments for, neurotraumatic diseases.
  • Neuronal Correlates of Empathy

    From Rodent to Human
    • 1st Edition
    • Ksenia Z. Meyza + 1 more
    • English
    Neuronal Correlates of Empathy: From Rodent to Human explores the neurobiology behind emotional contagion, compassionate behaviors and the similarities in rodents and human and non-human primates. The book provides clear and accessible information that avoids anthropomorphisms, reviews the latest research from the literature, and is essential reading for neuroscientists and others studying behavior, emotion and empathy impairments, both in basic research and preclinical studies. Though empathy is still considered by many to be a uniquely human trait, growing evidence suggests that it is present in other species, and that rodents, non-human primates, and humans share similarities.
  • Fundamentals of Cognitive Neuroscience

    A Beginner's Guide
    • 2nd Edition
    • Nicole M. Gage + 1 more
    • English
    Fundamentals of Cognitive Neuroscience: A Beginner's Guide, Second Edition, is a comprehensive, yet accessible, beginner’s guide on cognitive neuroscience. This text takes a distinctive, commonsense approach to help newcomers easily learn the basics of how the brain functions when we learn, act, feel, speak and socialize. This updated edition includes contents and features that are both academically rigorous and engaging, including a step-by-step introduction to the visible brain, colorful brain illustrations, and new chapters on emerging topics in cognition research, including emotion, sleep and disorders of consciousness, and discussions of novel findings that highlight cognitive neuroscience’s practical applications. Written by two leading experts in the field and thoroughly updated, this book remains an indispensable introduction to the study of cognition.
  • The Parietal Lobe

    • 1st Edition
    • Volume 151
    • English
    The Parietal Lobe, Volume 151, the latest release from the Handbook of Clinical Neurology series, provides a foundation on the neuroanatomy, neurophysiology and clinical neurology/neuropsych... of the parietal lobe that is not only applicable to both basic researchers and clinicians, but also to students and specialists who are interested in learning more about disorders brought on by damage or dysfunction. Topics encompass the evolution, anatomy, connections, and neurophysiology, the major neurological and neuropsychological deficits and syndromes caused by damage, the potential for improvement via transcranial stimulation, and the role of the parietal in the cerebral networks for perception and action.
  • Brain Banking

    • 1st Edition
    • Volume 150
    • English
    Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases.
  • Quality and Safety in Neurosurgery

    • 1st Edition
    • Daniel J. Guillaume + 1 more
    • English
    Quality and Safety in Neurosurgery covers recent improvements and presents solutions for problems that impact patient care. This book is written for anyone who works at the intersection of quality, safety and neurosurgery, including neurosurgeons, neurologists, clinical researchers looking to improve outcomes in neurosurgery, hospital quality and safety officers, department leaders, fellows and residents. Edited by neurosurgeons who helped build the culture of quality and safety in the Department of Neurosurgery at UMN, this work emphasizes quality and safety, whether through ‘value based purchasing’, finding specialty specific quality and safety metrics, or just the professional desire to provide quality care.
  • Type 2 Diabetes and Dementia

    • 1st Edition
    • Velandai Srikanth + 1 more
    • English
    Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology.
  • Atlas of the Developing Rat Nervous System

    • 4th Edition
    • George Paxinos + 1 more
    • English
    Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility.
  • Neurogenetics, Part II

    • 1st Edition
    • Volume 148
    • English
    Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses.
  • Understanding Intuition

    A Journey In and Out of Science
    • 1st Edition
    • Lois Isenman
    • English
    Understanding Intuition: A Journey In and Out of Science explores the biological and cognitive mechanisms that account for intuition, and examines the first-person experience. The book integrates both scientific and personal perspectives on this important yet elusive mental capacity. It uses specific encounters to illustrate that intuition is enhanced when we can attend to the subtle aspects of our inner experiences, such as bodily sensations, images, and differing kinds of intuitive evaluative feelings, all of which may emerge no further than on the fringe of awareness. This awareness of subtle inner experiences helps forge a more fluid exchange between the unconscious and conscious minds, and allows readers to calibrate their own intuitions. Over the course of the book, readers will gain a deeper appreciation and respect for the unconscious mind and its potential sophistication, and even its potential wisdom. Understanding Intuition is a timely and critical resource for students and researchers in psychology, cognitive science, theology, women’s studies, and neuroscience.
  • Direct versus Indirect Realism

    A Neurophilosophical Debate on Consciousness
    • 1st Edition
    • John R. Smythies + 1 more
    • English
    Direct versus Indirect Realism: A Neurophilosophical Debate on Consciousness brings together leading neuroscientists and philosophers to explain and defend their theories on consciousness. The book offers a one-of-a-kind look at the radically opposing theories concerning the nature of the objects of immediate perception—whether these are distal physical objects or phenomenal experiences in the conscious mind. Each side—neuroscientists and philosophers—offers accessible, comprehensive explanations of their points-of-view, with each side also providing a response to the other that offers a unique approach on opposing positions. It is the only book available that combines thorough discussion of the arguments behind both direct and indirect realism in a single resource, and is required reading for neuroscientists, neurophilosophers, cognitive scientists and anyone interested in conscious perception and the mind-brain connection.
  • Neurogenetics, Part I

    • 1st Edition
    • Volume 147
    • English
    Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist.
  • Neuromodulation

    Comprehensive Textbook of Principles, Technologies, and Therapies
    • 2nd Edition
    • Elliot Krames + 2 more
    • English
    Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine.
  • Handbook of Developmental Neurotoxicology

    • 2nd Edition
    • William Slikker Jr. + 2 more
    • English
    Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience.
  • Metastatic Disease of the Nervous System

    • 1st Edition
    • Volume 149
    • David Schiff + 1 more
    • English
    Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail.
  • Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases

    Overview of Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine
    • 1st Edition
    • Emilija Veljkovic + 7 more
    • English
    Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases: Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine provides a comprehensive summary of the epidemiological data on smoking and several neurological disorders, including Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Tourette’s syndrome, schizophrenia, anxiety, depression and ADHD, as well as preclinical and clinical data on the effects of nicotine. Despite the obvious and undisputed harmful nature of smoking, evidence suggests that some tobacco and tobacco smoke-derived constituents may offer neuroprotective effects, possibly in combinations, rather than individually. This unprecedented book describes the complex relationships between smoking and neurological disease and the bioactive compounds found in tobacco. It provides a comprehensive review of nicotine and other compounds found in tobacco plant, with scientific evidence of neuroprotective and anti-inflammatory effects that may act in conjunction with nicotine to exert neuroprotective effects observed in smokers. By presenting findings beyond harmful cigarette smoke effects, attention can be drawn to individual compounds of tobacco that may serve as inspiration for further therapy development.
  • Sleep, Epilepsies, and Cognitive Impairment

    • 1st Edition
    • Peter Halasz + 1 more
    • English
    Translational research connects science and clinical medicine from "the bench to the bedside." In Sleep, Epilepsies and Cognitive Impairment, the authors look back from the bedside to the brain function underlying clinical symptoms and reveal mechanisms explored by contemporary neuroimaging and signal analysis in the overlapping fields of sleep and epilepsy. This book will help the reader to see epilepsy from a new viewpoint. The common pathophysiology binding together the diverse manifestations of epilepsies is the exaggeration of plastic functions of the brain involving the hippocampus, the non-specific thalamocortical system and the perisylvian cognitive network. Epileptic derailment seems to be the price for the latest achievements of the mammal and human brain; namely the highly developed ability to change and learn. The contemporary results of sleep research provide new viewpoints to explain why sleep and epilepsy are bedfellows. Converging evidence supports the concept that one of the most important biological roles of NREM sleep is the renewal of synaptic balance ensuring learning ability from one day to the next and consolidation of new memories. Epilepsy and NREM sleep use overlapping structures and functions, therefore epilepsy beginning in early childhood may interfere with sleep plastic functions. NREM sleep, which affects original learning and memory, may become the hidden source of chronic cognitive impairment when epilepsy occurs during sleep and blocks the plastic processes. Sleep, Epilepsies and Cognitive Impairment abandons the academic classification of epilepsy by following the system epilepsy concept, binding major epilepsies with structures and functions of physiological brain systems. It tries to show within this system the close interrelationship between sleep, epilepsy and cognition. Neuroscientists, clinical epileptologists and neurologists interested in brain processes underlying brain plasticity, sleep and epilepsy will find this book thought provoking. It offers good "brain-gymnastics" for reconsidering the ideas on epilepsy.
  • Sixth International Congress of Neurology

    Brussels, 21–28 July 1957
    • 1st Edition
    • L. van Bogaert + 1 more
    • English
    Neurology, Volume 1 presents the proceedings of the First International Congress of Neurological Sciences, held in Brussels, Belgium, on July 21–28, 1957. This book provides information pertinent to the fundamental aspects of neurology. Organized into 107 chapters, this compilation of papers begins with an overview of the significance of genetic factors in multiple sclerosis wherein its occurrence in more than one member of a family have a very limited value. This text then examines the two common disorders, namely, cervical spondylosis and disseminated sclerosis. Other chapters explain the mechanism of demyelination problem in considering the pathology of multiple sclerosis or any of the degenerative diseases of the nervous system. This book discusses as well the commonest types of headaches observed, including tension headache, migraine headache, post-traumatic headache, and those associated with hypertension. The final chapter deals with cerebellar ataxia, chronic respiratory infection, and telangiectasia. This book is a valuable resource for neurologists, psychiatrists, and neuropsychiatrists.
  • Netter's Neurology

    • 3rd Edition
    • Jayashri Srinivasan + 3 more
    • English
    Perfect for residents, medical students, generalists, nurses, and other healthcare professionals who need a practical, working knowledge of neurology, Netter's Neurology, 3rd Edition, provides a concise overview highlighted by unique, memorable Netter illustrations. This award-winning visual resource showcases the well-known work of Frank H. Netter, MD, and his successor, Carlos Machado, MD, a physician who has created clear, full-color illustrations in the Netter tradition.
  • The Rat Brain in Stereotaxic Coordinates: Compact

    • 7th Edition
    • George Paxinos + 1 more
    • English
    The Rat Brain in Stereotaxic Coordinates Compact, Seventh Edition is a smaller sized (8.5 x 11inch), abridged version of the most referenced work in neuroscience (over 35,000 citations). The compact edition provides the coronal plates and diagrams of the current seventh edition in a smaller, more convenient spiral format and at a student friendly price. This book includes an introduction on current concepts in neuroanatomy, such as neuromeres and brain development. Students and seasoned researchers will find the first major unified nomenclature ontology tree based on development that features coronal photographic plates and juxtaposed diagrams.
  • Imaging of Brain Concussion, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 28-1
    • Roy Riascos + 1 more
    • English
    This issue of Neuroimaging Clinics of North America focuses on Imaging of Brain Concussion, and is edited by Drs. Roy Riascos and Eliana E. Bonfante-Mejia. Articles will include: Traumatic Brain Injury: definition, neurosurgery, trauma-orthopedics, neuroimaging, and psychology-psychiatr... Multimodality advanced imaging for brain concussions; Perfusion weighted images in brain concussion; PET and SPECT in brain concussion; Imaging of chronic concussion; Imaging of concussion in young athletes; Imaging on concussion in blast injury; Conventional CT and MR in brain concussion; Structural imaging: structural MRI in concussion; Susceptibility weighted imaging and MR spectroscopy in concussion; Functional imaging fMRI – BOLD and resting state techniques in mTBI; Diffusion Weighted and Diffusion Tensor Imaging in mTBI; and more!
  • Multiple Sclerosis, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 36-1
    • Darin T. Okuda
    • English
    This issue of Neurologic Clinics, edited by Dr. Darin T. Okuda, focuses on Multiple Sclerosis. Topics include, but are not limited to, Myelin and Axonal Repair Strategies in Multiple Sclerosis; Common Clinical and Imaging Conditions Misdiagnosed as Multiple Sclerosis; Topographical Model for Multiple Sclerosis: A Novel Approach to Understanding Clinical Phenotypes and Disease Activity; Incidental Anomalies Characteristic of CNS Demyelination: Radiologically Isolated Syndrome; Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management; Progressive Forms of Multiple Sclerosis: Distinct Entity or Time Dependent Phenomena; Advanced Symptom Management Strategies in Multiple Sclerosis, Ethnic Considerations and Multiple Sclerosis Disease Variability; The Dynamics of the Gut Microbiome in Multiple Sclerosis in Relation to Disease; Spinal Cord Imaging in Relation to Clinical Status in Multiple Sclerosis, and more.
  • Neurofeedback

    Tools, Methods and Applications
    • 1st Edition
    • Pascale Vincent
    • English
    The artificial intelligence of robots capable of learning from their errors and modifying their behavior accordingly is modeled on the activity of neurons in the brain.Emotional stress, traffic accidents, bereavement; these are all factors that can disrupt this neural activity, sometimes to the point of generating suffering that can be difficult to relieve. Neurofeedback, derived from neuroscience, is a computerized technique for training and re-balancing the brain’s electrical activity using neuroplasticity, which allows the brain to self-correct and regain a stable equilibrium, thus promoting recovery from traumas and a return to well-being. Neurofeedback: Tools, Methods and Applications deals with neurofeedback, explaining the functioning of the tool, its action on the equilibration of neural activity, and the differences between classical and dynamic systems. The results of the author's research and observations, the applications of these two tools, and the effects produced on the patients are explored, along with testimonies that describe and explain concepts in detail.Different neurofeedback tools are presented in this book, together with their function and explicit specificities adapted to the needs of each user. Their applications to psychological and cognitive disorders make neurofeedback an efficient and promising neurotherapy technique.
  • Temporal Sampling and Representation Updating

    • 1st Edition
    • Volume 236
    • English
    Temporal Sampling and Representation Updating, Volume 236, addresses the gap between laboratory studies using static or predictable stimuli and the more complex change that is a characteristic of the real world. Topics in this new volume include a section on Unfolding the time course of emotion perception, Temporal sampling and representation updating for action in interception and grasping tasks, The influence of Cognitive Control and Attention on Temporal Sampling: Lessons from the Attentional Blink, Synchronizing tracking eye movements with the motion of a visual target, and Sampling feature distributions with visual search in heterogeneous displays.
  • Cerebrospinal Fluid in Neurologic Disorders

    • 1st Edition
    • Volume 146
    • English
    Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice.
  • The Lateralized Brain

    The Neuroscience and Evolution of Hemispheric Asymmetries
    • 1st Edition
    • Sebastian Ocklenburg + 1 more
    • English
    The Lateralized Brain: The Neuroscience and Evolution of Hemispheric Asymmetries is an up-to-date teaching resource for neuroscience faculty members that teach courses concerning hemispheric asymmetries. The book provides students with all relevant information on the subject, while also giving aspiring researchers in the field an up-to-date overview of relevant, previous work. It is ideal for courses on hemispheric asymmetries, that is, the functional or structural differences between the left and the right hemispheres of the brain, and also highlights how the widespread use of modern neuroimaging techniques, such as fMRI and DTI has completely changed the way hemispheric asymmetries are currently investigated. According to the preface, the main aim of The Lateralized Brain is to provide "an up-to-date teaching resource on hemispheric asymmetries … [and] to introduce undergraduate students of all levels to the fascinating topics of hemispheric asymmetries" (p. xv)… (Sebastian Ocklenburg and Onur Güntürkün) have succeeded admirably in their stated aim and are to be congratulated on undertaking the mammoth task they set themselves. They can be proud of what they have accomplished.~ Alan A. Beaton, Department of Psychology, Swansea University, Swansea, UK, in Laterality: Asymmetries of Body, Brain and Cognition, July, 2018.
  • Intracranial Epidural Bleeding

    History, Management, and Pathophysiology
    • 1st Edition
    • Jeremy Christopher Ganz
    • English
    Intracranial Epidural Bleeding: History, Management, and Pathophysiology examines the history of the concepts underlying the understanding of the clinical features of epidural bleeding. The pathophysiology of epidural bleeding was examined in two PhD theses in the 1980s, with the results published in top international journals. However, these concepts have not been understood by the general neurosurgical community. This book provides a comprehensive overview of how epidural bleeding actually works. It can be used to help improve the interpretation of images during management, and to assess degrees of urgency. This book is written for neurosurgeons, neurologists, cerebrovascular physiologists, trauma surgeons, and medical historians.
  • Neuromonitoring Techniques

    Quick Guide for Clinicians and Residents
    • 1st Edition
    • Hemanshu Prabhakar
    • English
    Neuromonitoring Techniques: Quick Guide for Clinicians and Residents provides a quick and easy guide to understanding various neuromonitoring equipment. Chapters include intracranial pressure monitoring, EEG-based monitors, evoked potentials and transcranial doppler. This book is written for trainees, clinicians and researchers in the fields of neurosurgery, neurocritical care, neuroradiology, neuroanesthesia and neurology. As specialized neuromonitoring is now routinely done in neurosurgical cases, it provides an important resource for neurologists, neurophysiologists, anesthesiologists and residents who are expected to have theoretical and practical knowledge on different systems. Each monitoring system is discussed separately, with examples, images, reference values and their interpretations.
  • Handbook of Neuroemergency Clinical Trials

    • 2nd Edition
    • Brett E. Skolnick + 1 more
    • English
    Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development.
  • Reasoning

    The Neuroscience of How We Think
    • 1st Edition
    • Daniel Krawczyk
    • English
    Reasoning: The Neuroscience of How We Think is a comprehensive guide to the core topics related to a thorough understanding of reasoning. It presents the current knowledge of the subject in a unified, complete manner, ranging from animal studies, to applied situations, and is the only book available that presents a sustained focus on the neurobiological processes behind reasoning throughout all chapters, while also synthesizing research from animal behavior, cognitive psychology, development, and philosophy for a truly multidisciplinary approach. The book considers historical perspectives, state-of-the-art research methods, and future directions in emerging technology and cognitive enhancement. Written by an expert in the field, this book provides a coherent and structured narrative appropriate for students in need of an introduction to the topic of reasoning as well as researchers seeking well-rounded foundational content. It is essential reading for neuroscientists, cognitive scientists, neuropsychologists and others interested in the neural mechanisms behind thinking, reasoning and higher cognition.
  • Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline.
  • Neuropathology

    • 1st Edition
    • Volume 145
    • English
    Neuropathology, Volume 145, the latest release in the Handbook of Clinical Neurology series, includes all the major topics found in a typical neuropathology text, but differentiates itself by providing a thorough overview of the morphological background of neurological disorders for researchers and clinicians who do not specialize in pathology or its clinicopathological aspects. This volume offers strong coverage of brain imaging and advances in molecular pathology and genetics, and is particularly timely given the amount of neuropathological research currently taking place.
  • The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

    • 1st Edition
    • Volume 136
    • English
    The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders.
  • The Neurobiology of Brain and Behavioral Development

    • 1st Edition
    • Robbin Gibb + 1 more
    • English
    The Neurobiology of Brain and Behavioral Development provides an overview of the process of brain development, including recent discoveries on how the brain develops. This book collates and integrates these findings, weaving the latest information with core information on the neurobiology of brain development. It focuses on cortical development, but also features discussions on how the other parts of the brain wire into the developing cerebral cortex. A systems approach is used to describe the anatomical underpinnings of behavioral development, connecting anatomical and molecular features of brain development with behavioral development.The disruptors of typical brain development are discussed in appropriate sections, as is the science of epigenetics that presents a novel and instructive approach on how experiences, both individual and intergenerational, can alter features of brain development. What distinguishes this book from others in the field is its focus on both molecular mechanisms and behavioral outcomes. This body of knowledge contributes to our understanding of the fundamentals of brain plasticity and metaplasticity, both of which are also showcased in this book.
  • Brain Research in Addiction

    • 1st Edition
    • Volume 235
    • English
    Brain Research in Addiction, Volume 235, the latest volume in this groundbreaking series on addiction, presents the neurobiological, pathological, cognitive and evolutionary aspects of addiction, with new chapters covering the Neurobiology of drug intake escalation, the Role of the orexinergic system in reward, Mental time travel and addictive behaviors, An evolutionary perspective on addiction- Addiction is the price we pay for innovation and adaptability, and how Cocaine exposure affects object-place recognition memory in non-human primates. Chapters in this serial are presented by leading researchers from North America, South America, Europe, Africa, Asia and Australia, who present addiction research from the bottom up, including how addiction evolved, basic research on animal models, and the psychiatric, psychological and cognitive characteristics of addictive behaviors in humans.
  • Sport and the Brain: The Science of Preparing, Enduring and Winning, Part B

    • 1st Edition
    • Volume 234
    • English
    Sport and the Brain: The Science of Preparing, Enduring and Winning, Part B, Volume 233 reflects recent advancements in the understanding of how elite athletes prepare for, and perform at, peak levels under the demands of competition. Topics discussed in this new release include a section on Exploring the Applicability of the Contextual Interference Effect in Sports Practice, The Resonant System: Linking Brain-body-environme... in Sport Performance, the Effects of Acute High-intensity Exercise on Cognitive Performance in Trained Individuals: A Systematic Review, Moving Concussion Care to the Next Level: The Emergence and Role of Concussion Clinics in the UK, and Neurocognitive Mechanisms of the Flow State. This longstanding series takes a multidisciplinary approach, focusing on aspects of psychology, neuroscience, skill learning, talent development and physiology.
  • Functional Connectivity, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 27-4
    • Jay J. Pillai
    • English
    This issue of Neuroimaging Clinics of North America focuses on Functional Connectivity, and is edited by Dr. Jay Pillai. Articles will include: Applications of rs-fMRI to presurgical mapping: sensorimotor mapping; Dynamic functional connectivity methods; Machine learning applications to rs-fMRI analysis; Frequency domain analysis of rs-fMRI; Applications of rs-fMRI to epilepsy; Data-driven analysis methods for rs-fMRI; Applications of rs-fMRI to presurgical mapping: language mapping; Limitations of rs-fMRI in the setting of focal brain lesions; Applications of rs-fMRI to neuropsychiatric disease; Applications of rs-fMRI to Traumatic Brain Injury; Applications of rs-fMRI to neurodegenerative disease; Graph theoretic analysis of rs-fMRI; and more!
  • Neurocritical Care, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 35-4
    • Alejandro A. Rabinstein
    • English
    This issue of Neurologic Clinics, edited by Dr. Alejandro A. Rabinstein, will cover Neurocritical Care. Topics include, but are not limited to: Anoxic Brain Injury; Treatment of Intracranial Hypertension; Management of Traumatic Brain Injury; Cortical Spreading Depression and Ischemia in Neurocritical Patients; Temperature Control in Acute Brain Injury; HSV Encephalitis; Primary Acute Neuromuscular Respiratory Failure; ICU-Acquired Weakness; Emergency and Critical Care Management of Intracerebral Hemorrhage; New developments in Refractory Status Epilepticus; Acute Cardiac Complications in Critical Brain Disease; Nosocomial Infections in Neurocritical Patients; Neurological Complications after Solid Organ Transplantation; and Shared Decision Making in the NICU.
  • Arachnoid Cysts

    Clinical and Surgical Management
    • 1st Edition
    • Knut Wester
    • English
    Arachnoid Cysts: Clinical and Surgical Management gives a broad and updated presentation of the condition, including symptomatology, diagnostics, management and treatment. The book covers the effects of surgical treatment on clinical symptoms and the effects cysts have on cognition, as well as cognitive improvement after surgical cyst decompression. This book is written for researchers, residents and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology and pediatrics.
  • Arachnoid Cysts

    Epidemiology, Biology, and Neuroimaging
    • 1st Edition
    • Knut Wester
    • English
    Intracranial arachnoid cysts are congenital malformations with a predilection for the middle cranial fossa and an estimated prevalence in the general population as high as 1.7%. The common assumption is that these cysts are incidental findings and the symptoms associated with them are not caused by the cyst and consequently, that surgical intervention will not benefit the patient. However, there is now a growing understanding reflected in the international literature among neurologists and neurosurgeons that arachnoid cysts do harm and that the patients’ complaints can be relieved by surgical treatment. Arachnoid Cysts: Epidemiology, Biology, and Neuroimaging gives a broad and updated presentation of the condition, including epidemiology, etiology, biology (including genetics and molecular biology), and neuroimaging of same. This book is written for researchers, residents, and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology, and pediatrics.
  • Finding the Nerve

    The Story of Impedance Neurography
    • 1st Edition
    • Philip C Cory
    • English
    Finding the Nerve: The Story of Impedance Neurography discusses research that elucidates the nature of nerve simulation via externally applied electrical fields, and how it has led to an entirely new understanding of neuronal cell membrane biophysics and defined a novel nerve imaging technology. It details how these discoveries came about and the nature of research that derives from unexplained clinical observations. The primary technology, impedance neurography, is a wholly new way of nerve-specific visualization in 2-D or 3-D, with the ability to define both normal and abnormal functioning of nerves, heretofore unavailable from techniques such as MRI neurography. This is of particular importance with respect to the obesity epidemic where physicians performing nerve-related procedures cannot use ultrasound visualization due to the depth limitations of that technology.
  • Environmental Causes and Prevention Measures for Alzheimer’s Disease

    • 1st Edition
    • George J. Brewer
    • English
    Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.
  • SPEC – Handbook of Clinical Neurology, Volume 144, Huntington Disease, 12-Month Access, eBook

    • 1st Edition
    • Volume 144
    • English
    Huntington Disease summarizes the most recent findings related to the disease, providing both cutting edge coverage for clinical/research specialists looking to expand their knowledge base of Huntington disease information, as well as solid groundwork for advanced students from various backgrounds (neurology, psychiatry, neuropsychology, genetics). The volume includes all major areas of Huntington disease clinical care and research, whereas many other HD texts focus solely on neurological symptoms. This book also addresses behavioral and cognitive symptoms, brain imaging, and family dynamics and therapeutic alliances in working with individuals affected by HD. Clinical trials are covered extensively, including design considerations for therapeutic studies. The devastating nature of Huntington’s disease is well appreciated throughout the neuroscience, neurology, and psychiatric communities, and a great amount of basic and clinical research is currently taking place. However, much of that occurs in isolated research silos, and it is critical that an interdisciplinary resource be developed to provide in depth information to enhance communication and collaboration. This volume in the Handbook of Clinical Neurology series is that resource.
  • Neuroepidemiology in Tropical Health

    • 1st Edition
    • Pierre-Marie Preux + 1 more
    • English
    Neuroepidemiology in Tropical Health covers major neurological diseases of relevance in tropical settings and examines the specificities of epidemiology of neurological diseases in the context of tropical countries that face many challenges when compared to the developed world. Part One focuses on methods and their eventual specificities, and how such methods, like sampling, can be adapted for specific scenarios. Parts Two and Three discuss environmental factors and their consequences for neurology in the tropical world, as well as large geographical areas and their specificities. Finally, Part Four presents relevant neurological diseases in in-depth chapters. This invaluable information will help readers recognize the various neurological conditions presented, with the inclusion of their aetiologies and treatment in tropical areas. The book therefore fills a gap in the neuroepidemiology literature, with chapters written by an international collection of experienced authors in the field.
  • Computational Psychiatry

    Mathematical Modeling of Mental Illness
    • 1st Edition
    • Alan Anticevic + 1 more
    • English
    Computational Psychiatry: Mathematical Modeling of Mental Illness is the first systematic effort to bring together leading scholars in the fields of psychiatry and computational neuroscience who have conducted the most impactful research and scholarship in this area. It includes an introduction outlining the challenges and opportunities facing the field of psychiatry that is followed by a detailed treatment of computational methods used in the service of understanding neuropsychiatric symptoms, improving diagnosis and guiding treatments. This book provides a vital resource for the clinical neuroscience community with an in-depth treatment of various computational neuroscience approaches geared towards understanding psychiatric phenomena. Its most valuable feature is a comprehensive survey of work from leaders in this field.