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Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also… Read more
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Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function.
In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.
SECTION I. THERMOREGULATION SYSTEM
1. The thermoregulation system and how it works
SECTION II. THERMORECEPTORS
2. Peripheral thermoreceptors in innocuous temperature detection
3. Molecular basis of peripheral innocuous cold sensitivity
4. Molecular basis of peripheral innocuous warmth sensitivity
5. Peripheral and central determinants of skin wetness sensing in humans
6. Nociceptors. Thermal allodynia and thermal pain
7. Central thermoreceptors
8. Molecular Basis of Central Thermosensation
SECTION III. THERMOEFFECTORS
9. Brown adipose tissue as a heat-production thermoeffector
10. Shivering and nonshivering thermogenesis in skeletal muscles
11. Skin vasoconstriction as a heat-conservation thermoeffector
12. Cutaneous active vasodilation as a heat-loss thermoeffector
13. Sweating as a heat-loss thermoeffector
14. Panting as a heat-loss thermoeffector
15. Thermal comfort
SECTION IV. NEURAL PATHWAYS
16. Afferent pathways for autonomic and shivering thermoeffectors
17. Efferent neural pathways for the control of brown adipose tissue thermogenesis and shivering
18. Efferent thermoregulatory pathways regulating cutaneous blood flow and sweating
19. Central neural substrates involved in temperature discrimination, thermal pain, thermal comfort, and thermoregulatory behavior
SECTION V. THERMOREGULATION AS A HOMEOSTATIC FUNCTION
20. Body temperature and sleep
21. Skin Temperature, Sleep and Vigilance
22. Thermoregulation and the ultradian basic rest-activity cycle
23. Thermoregulation and age
24. Temperature and adaptive immunity
25. Interactions between body fluid homeostasis and thermoregulation in humans
26. Obesity and Thermoregulation
27. Thermoregulation and nausea
28. Neurogenesis in the thermoregulatory system
AR