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Elsevier

Books in Life sciences

  • Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci

    • 1st Edition
    • Volume 128
    • English
    Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.

  • Nicotine Use in Mental Illness and Neurological Disorders

    • 1st Edition
    • Volume 124
    • English
    Nicotine Use in Mental Illness and Neurological Disorders, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into nicotine use in mental illness and neurological disorders. It reviews current knowledge and understanding, also provides a starting point for researchers and practitioners entering the field.

  • Genetic Control of Malaria and Dengue

    • 1st Edition
    • Zach N. Adelman
    • English
    Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown.

  • Essential Chemistry for Formulators of Semisolid and Liquid Dosages

    • 1st Edition
    • Vitthal S. Kulkarni + 1 more
    • English
    A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosit... microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.

  • Meyler's Side Effects of Drugs

    The International Encyclopedia of Adverse Drug Reactions and Interactions
    • 16th Edition
    • Jeffrey K. Aronson
    • English
    Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles.

  • Shoulder and Elbow Trauma and its Complications

    Volume 2: The Elbow
    • 1st Edition
    • Michael Greiwe
    • English
    Shoulder and Elbow Trauma and Its Complications: Volume 2: The Elbow provides an update on elbow surgery, a type of procedure that is seeing a significant increase in recent years. Although some of these surgeries are due to an aging population, a large proportion of operations are being performed on younger patients who have damaged their joints through physical activity. Worldwide, many of the injuries sustained through sport and physical activity are fractures which can be difficult to treat and can cause complications. Chapters in this detailed book will look at the most common types of elbow trauma and how to manage complications in surgery.

  • Human Physiology, Biochemistry and Basic Medicine

    • 1st Edition
    • Laurence A. Cole + 1 more
    • English
    Human Physiology, Biochemistry and Basic Medicine is a unique perspective that draws together human biology, physiology, biochemistry, nutrition, and cell biology in one comprehensive volume. In this way, it is uniquely qualified to address the needs of the emerging field of humanology, a holistic approach to understanding the biology of humans and how they are distinguished from other animals. Coverage starts with human anatomy and physiology and the details of the workings of all parts of the male and female body. Next, coverage of human biochemistry and how sugars, fats, and amino acids are made and digested is discussed, as is human basic medicine, covering the science of diseases and human evolution and pseudo-evolution. The book concludes with coverage of basic human nutrition, diseases, and treatments, and contains broad coverage that will give the reader an understanding of the entire human picture.

  • Epigenomics in Health and Disease

    • 1st Edition
    • Mario Fraga + 1 more
    • English
    Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 72
    • English
    Advances in Clinical Chemistry, Volume 72, the latest installment in this internationally acclaimed series contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Advances in Molecular Toxicology

    • 1st Edition
    • Volume 9
    • English
    Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

  • The Epigenome and Developmental Origins of Health and Disease

    • 1st Edition
    • Cheryl S. Rosenfeld
    • English
    Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples.

  • Genetic Diagnosis of Endocrine Disorders

    • 2nd Edition
    • Roy E. Weiss + 1 more
    • English
    Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias.

  • Aquafeed Formulation

    • 1st Edition
    • Sergio F Nates
    • English
    Aquafeed Formulation is the only resource that provides summaries with examples and formulation techniques specifically to meet the needs of anyone in the aquaculture industry. As feed is the largest single cost item in aquaculture production, and formulating aquaculture feed requires many combinations of several ingredients and nutrient requirements, this book takes a clear-and -concise approach, providing essential information on formulation and covering relevant available software, feed nutrients, and additives such as enzymes and phytase and conjugated fatty acids, as well as best industry practices to improve aquafeed production. Users will find this to be a one-stop resource for anyone interested or involved in, the global aquaculture industry.

  • Basic Immunology

    Functions and Disorders of the Immune System
    • 5th Edition
    • Abul K. Abbas + 2 more
    • English
    In the Basic Immunology: Functions and Disorders of the Immune System, 5th Edition, the authors continue to deliver a clear, modern introduction to immunology, making this the obvious choice for today's busy students. Their experience as teachers, course directors, and lecturers helps them to distill the core information required to understand this complex field. Through the use of high-quality illustrations, relevant clinical cases, and concise, focused text, it's a perfectly accessible introduction to the workings of the human immune system, with an emphasis on clinical relevance.

  • Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part B

    • 1st Edition
    • Volume 564
    • English
    Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A & B, are the latest volumes in the Methods in Enzymology series, continuing the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods centered on the use of Electron Paramagnetic Resonance (EPR) techniques to study biological structure and function.

  • Pharmaceutical Microbiology

    Essentials for Quality Assurance and Quality Control
    • 1st Edition
    • Tim Sandle
    • English
    Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control presents that latest information on protecting pharmaceutical and healthcare products from spoilage by microorganisms, and protecting patients and consumers. With both sterile and non-sterile products, the effects can range from discoloration to the potential for fatality. The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.

  • New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System Part A

    • 1st Edition
    • Volume 220
    • English
    New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

  • Phase Transitions in Foods

    • 2nd Edition
    • Yrjo H Roos + 1 more
    • English
    Phase Transitions in Foods, Second Edition, assembles the most recent research and theories on the topic, describing the phase and state transitions that affect technological properties of biological materials occurring in food processing and storage. It covers the role of water as a plasticizer, the effect of transitions on mechanical and chemical changes, and the application of modeling in predicting stability rates of change. The volume presents methods for detecting changes in the physical state and various techniques used to analyze phase behavior of biopolymers and food components. It should become a valuable resource for anyone involved with food engineering, processing, storage, and quality, as well as those working on related properties of pharmaceuticals and other biopolymers.

  • Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A

    • 1st Edition
    • Volume 563
    • English
    Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A & B, are the latest volumes in the Methods in Enzymology series, continuing the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods centered on the use of Electron Paramagnetic Resonance (EPR) techniques to study biological structure and function.

  • Apoptosis and Development

    • 1st Edition
    • Volume 114
    • English
    Apoptosis and Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila.

  • Plant Factory

    An Indoor Vertical Farming System for Efficient Quality Food Production
    • 1st Edition
    • Toyoki Kozai + 2 more
    • English
    Plant Factory: An Indoor Vertical Farming System for Efficient Quality Food Production provides information on a field that is helping to offset the threats that unusual weather and shortages of land and natural resources bring to the food supply. As alternative options are needed to ensure adequate and efficient production of food, this book represents the only available resource to take a practical approach to the planning, design, and implementation of plant factory (PF) practices to yield food crops. The PF systems described in this book are based on a plant production system with artificial (electric) lights and include case studies providing lessons learned and best practices from both industrial and crop specific programs. With insights into the economics as well as the science of PF programs, this book is ideal for those in academic as well as industrial settings.

  • Molecular Microbial Diagnostic Methods

    Pathways to Implementation for the Food and Water Industries
    • 1st Edition
    • Nigel Cook + 2 more
    • English
    Molecular Microbial Diagnostic Methods: Pathways to Implementation for the Food and Water Industry was developed by recognized and experienced highlevel scientists. It’s a comprehensive and detailed reference that uncovers industry needs for the use of molecular methods by providing a brief history of water and food analysis for the pathogens of concern. It also describes the potential impact of current and cutting-edge molecular methods. This book discusses the advantages of the implementation of molecular methods, describes information on when and how to use specific methods, and presents why one should utilize them for pathogen detection in the routine laboratory. The content is also pertinent for anyone carrying out microbiological analysis at the research level, and for scientists developing methods, as it focuses on the requirements of end-users.

  • A Practical Guide to Rational Drug Design

    • 1st Edition
    • Sun Hongmao
    • English
    This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors’ active compounds or from natural ligands of the targets; how to springboard from competitors’ SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes.

  • Endoscopic Diagnosis and Treatment in Urethral Pathology

    Handbook of Endourology
    • 1st Edition
    • Petrisor Aurelian Geavlete
    • English
    Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format.Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

  • Concepts and Models for Drug Permeability Studies

    Cell and Tissue based In Vitro Culture Models
    • 1st Edition
    • Bruno Sarmento
    • English
    This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

  • Prostate Cancer

    Science and Clinical Practice
    • 2nd Edition
    • Jack H. Mydlo + 1 more
    • English
    Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials.

  • Essential Oils in Food Preservation, Flavor and Safety

    • 1st Edition
    • Victor R. Preedy
    • English
    Essential Oils in Food Preservation, Flavor and Safety discusses the major advances in the understanding of the Essential Oils and their application, providing a resource that takes into account the fact that there is little attention paid to the scientific basis or toxicity of these oils. This book provides an authoritative synopsis of many of the complex features of the essential oils as applied to food science, ranging from production and harvesting, to the anti-spoilage properties of individual components. It embraces a holistic approach to the topic, and is divided into two distinct parts, the general aspects and named essential oils. With more than 100 chapters in parts two and three, users will find valuable sections on botanical aspects, usage and applications, and a section on applications in food science that emphasizes the fact that essential oils are frequently used to impart flavor and aroma. However, more recently, their use as anti-spoilage agents has been extensively researched.

  • Bioengineering for Surgery

    The Critical Engineer Surgeon Interface
    • 1st Edition
    • Walid Farhat + 1 more
    • English
    Bioengineering is the application of engineering principles to address challenges in the fields of biology and medicine encompassing the principles of engineering design to the full spectrum of living systems. In surgery, recent advances in minimal invasive surgery and robotics are the culmination of the work that both engineers and surgeons have achieved in the medical field through an exciting and challenging interface. This interface rests on the medical curiosity and engineering solutions that lead eventually to collaboration and development of new ideas and technologies. Most recently, innovation by surgeons has become a fundamental contribution to medical research in the surgical field, and it is through effective communication between surgeons and biomedical engineers and promoting collaborative initiatives that translational research is possible. Bioengineering for Surgery explores this interface between surgeons and engineers and how it leads to innovation processes, providing clinical results, fundraising and prestige for the academic institution. This book is designed to teach students how engineers can fit in with their intended environment and what type of materials and design considerations must be taken into account in regards to medical ideas.

  • Integrated Management of Salt Affected Soils in Agriculture

    Incorporation of Soil Salinity Control Methods
    • 1st Edition
    • Nesreen Houssein Ahmen Abou-Baker + 1 more
    • English
    Integrated Management of Salt Affected Soils in Agriculture is a concise guide to evaluating and addressing soil issues related to saline content. Methods focused, the book combines agricultural and soil-based insights to efficiently remediate salt-affected soil. Environmental stress conditions such as salinity have a devastating impact on plant growth and yield, causing considerable loss to agricultural production worldwide. Soil salinity control prevents soil degradation by salinization and reclaim already saline soils. This book will help develop the proper management procedures, to solve problems of crop production on salt-affected soils.

  • Biomineralization and Biomaterials

    Fundamentals and Applications
    • 1st Edition
    • Conrado Aparicio + 1 more
    • English
    Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance.

  • Virus as Populations

    Composition, Complexity, Dynamics, and Biological Implications
    • 1st Edition
    • Esteban Domingo
    • English
    Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere.

  • Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions

    • 1st Edition
    • Volume 100
    • English
    Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions continues the tradition of the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 319
    • Kwang W. Jeon
    • English
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 71
    • English
    Advances in Clinical Chemistry, Volume 71, is the latest installment in this internationally acclaimed series. This latest volume contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Analytical Ultracentrifugation

    • 1st Edition
    • Volume 562
    • English
    Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals.

  • Advances in Genetics

    • 1st Edition
    • Volume 91
    • English
    Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing furture directions.

  • Kaufman’s Atlas of Mouse Development Supplement

    With Coronal Sections
    • 1st Edition
    • Richard Baldock + 3 more
    • English
    Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development.

  • Osteoimmunology

    Interactions of the Immune and Skeletal Systems
    • 2nd Edition
    • Joseph Lorenzo + 4 more
    • English
    Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis.

  • Probiotics, Prebiotics, and Synbiotics

    Bioactive Foods in Health Promotion
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion reviews and presents new hypotheses and conclusions on the effects of different bioactive components of probiotics, prebiotics, and synbiotics to prevent disease and improve the health of various populations. Experts define and support the actions of bacteria; bacteria modified bioflavonoids and prebiotic fibrous materials and vegetable compounds. A major emphasis is placed on the health-promoting activities and bioactive components of probiotic bacteria.

  • Structure to Function of G Protein-Gated Inwardly Rectifying (GIRK) Channels

    • 1st Edition
    • Volume 123
    • English
    This volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into GIRK Potassium Channels. It reviews current knowledge and understanding and provides a starting point for researchers and practitioners entering the field.

  • Advances in Agronomy

    • 1st Edition
    • Volume 134
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich and varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Molecular and Cellular Regulation of Adaptation to Exercise

    • 1st Edition
    • Volume 135
    • Claude Bouchard
    • English
    Molecular Aspects of Exercise Biology and Exercise Genomics, the latest volume in the Progress in Molecular Biology and Translational Science series includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. Changes in the cellular machinery are described for multiple tissues and organs in terms of signaling pathways, gene expression, and protein abundance. Adaptations to acute exercise as well as exposure to regular exercise are also discussed and considered.

  • Thermal Imaging Techniques to Survey and Monitor Animals in the Wild

    A Methodology
    • 1st Edition
    • Kirk J Havens + 1 more
    • English
    Thermal Imaging Techniques to Survey and Monitor Animals in the Wild: A Methodology provides a manual for anyone interested in understanding thermal imaging and its usefulness in solving a wide range of problems regarding the observation of wildlife. In the last decade, the cost of thermal imaging technology has significantly decreased, making the equipment more widely available. This book offers an overview of thermal physics and the thermal imager, along with a methodology to optimize the window of opportunity so that wildlife can be observed and studied in their natural habitat. Users will find the knowledge and tools to formulate a sound survey design, with detailed sections on the theory and performance characteristics of thermal imaging cameras utilizing cooled quantum detectors as the sensitive element and additional information on the uncooled micro bolometric imagers which have been introduced into the camera market in past decades. The methodology presented is logical and simple, yet it presents a detailed understanding of the topic and how it applies to the critically interlinked disciplines of biology, physics, micrometeorology, and animal physiology.

  • The Choroid Plexus and Cerebrospinal Fluid

    Emerging Roles in CNS Development, Maintenance, and Disease Progression
    • 1st Edition
    • Josh Neman + 1 more
    • English
    The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines new and established work to allow for cross-disciplinary discussion and showcase newfound excitement surrounding the choroid plexus and cerebrospinal fluid (CSF). This book is of great utility to neuroscientists interested in biological questions about cancer, multiple sclerosis, Alzheimer’s, choroid plexus, or CSF research, and especially for researchers looking to expand their research into later stages of their disease of interest, such as metastasis. No other resource is currently available which addresses these issues in this fashion. The focus on the choroid plexus provides a practical resource on modeling clinical issues influenced by this brain region for researchers from students to principal investigators.

  • Laboratory Animal Anaesthesia

    • 4th Edition
    • Paul Flecknell
    • English
    Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a very diverse audience needing content, with straight-forward, structured style of writing. Updated with effects of anaesthetics in different laboratory species, including sources of dose rates will be incorporated into tabular material. New information on pain assessment and pain management will be covered, and an increased emphasis on rats and mice for anaesthesia and perioperative care. With newly revised, full color illustrations to facilitate best learning, Laboratory animal Anesthesia, Fourth Edition provides procedures, key points and invaluable advice from a well-known and respected veterinary anesthetist and scientist with over 30 years of experience in the field.

  • Dimensional Analysis of Food Processes

    • 1st Edition
    • Guillaume Delaplace + 3 more
    • English
    This book deals with the modeling of food processing using dimensional analysis. When coupled to experiments and to the theory of similarity, dimensional analysis is indeed a generic, powerful and rigorous tool making it possible to understand and model complex processes for design, scale-up and /or optimization purposes. This book presents the theoretical basis of dimensional analysis with a step by step detail of the framework for applying dimensional analysis, with chapters respectively dedicated to the extension of dimensional analysis to changing physical properties and to the use of dimensional analysis as a tool for scaling-up processes. It includes several original examples issued from the research works of the authors in the food engineering field, illustrating the conceptual approaches presented and strengthen the teaching of all.

  • Physical-Chemical Properties of Foods

    New Tools for Prediction
    • 1st Edition
    • Aïchatou Musavu Ndob + 2 more
    • English
    The physical and chemical properties of food products have central roles in biotechnology and the pharmaceutical and food industries. Understanding these properties is essential for engineers and scientists to tackle the numerous issues in food processing, including preservation, storage, distribution and consumption.This book discusses models to predict some of the physical-chemical properties (pH, aw and ionic strength) for biological media containing various solutes. In recent years, food production has involved less processing and fewer additives or preservatives. If health benefits for consumers are obvious, it is not only necessary to adapt current processing and preservation processes but also to verify that appropriate technological and health properties are preserved.The authors present established models, but also introduce new tools for prediction with modeling methods that are part of a more general approach to understand the behavior of fluid mixtures and design new products or processes through numerical simulation.

  • A Monograph of Codonopsis and Allied Genera (Campanulaceae)

    • 1st Edition
    • De-Yuan Hong
    • English
    Codonopsis and its allied genera, are a group of plants which are important in economy and horticulture. A Monograph of Codonopsis and Allied Genera (Campanulaceae s. str.) offers its audience comprehensive knowledge of these plants including palynology, cytology, population biology, morphological description, geographical distribution with vouchers cited, excellent ink illustrations, and color photos, and keys to genera and to species. This excellent work will facilitate identification of relevant plants, use of plant resources, assessment of endangered states, the development of conservation strategies, and will promote systematic and evolutionary research of this group.

  • Omic Studies of Neurodegenerative Disease - Part B

    • 1st Edition
    • Volume 122
    • English
    Omic Studies of Neurodegenerative Disease: Part B is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields. The book informs the reader on the current state of the studies used to evaluate the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research.

  • Mineral Nutrition of Fruit Trees

    Studies in the Agricultural and Food Sciences
    • 1st Edition
    • D. Atkinson + 2 more
    • English
    Mineral Nutrition of Fruit Trees summarizes the state of knowledge about the mineral nutrition of fruit trees, including peach and apple trees. The discussions are organized around six themes: fruit tree mineral nutrition and crop quality; uptake and transport; effect of soil management and fertilizer applications on nutrient uptake; direct application of nutrients to foliage and fruits; prediction of nutrient requirements; and synthesis. This text consists of 69 chapters and begins with a section dealing with the effects of nutrition on fruit quality. The second section explores the mechanisms of nutrient entry to, and movement within, fruit trees and the means of influencing the nutrition of both the whole tree and the crop by fertilizers and management practices, including irrigation and the use of herbicides. The third section describes methods for predicting the needs of the tree for establishment, growth, and fruit quality. The effects of interactions between nutrition and environment on the mineral composition of fruits are considered, along with an integrated approach to orchard nutrition and bitter pit control, the influence of boron deficiency on fruit quality, and calcium accumulation in apple fruit. This book will be of interest to scientists working in fields such as biochemistry, food technology, agriculture, horticulture, and physiology.

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