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Elsevier

Basic Immunology

Functions and Disorders of the Immune System

  • 5th Edition - October 7, 2015
  • Latest edition
  • Authors: Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai
  • Language: English

In the Basic Immunology: Functions and Disorders of the Immune System, 5th Edition, the authors continue to deliver a clear, modern introduction to immunology, making this the ob… Read more

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Description

In the Basic Immunology: Functions and Disorders of the Immune System, 5th Edition, the authors continue to deliver a clear, modern introduction to immunology, making this the obvious choice for today's busy students. Their experience as teachers, course directors, and lecturers helps them to distill the core information required to understand this complex field. Through the use of high-quality illustrations, relevant clinical cases, and concise, focused text, it's a perfectly accessible introduction to the workings of the human immune system, with an emphasis on clinical relevance.

Key features

  • Concise, clinically focused content is logically organized by mechanism for efficient mastery of the material
  • Features an appendix of clinical cases and CD molecules
  • Includes numerous full-color illustrations, useful tables, and chapter outlines
  • Focus questions within each chapter are ideal for self-assessment and review
  • Key points bolded throughout the text make it easy to locate important information

Table of contents

1. INTRODUCTION TO THE IMMUNE SYSTEM
Nomenclature, General Properties, and Components

2. INNATE IMMUNITY
The Early Defense Against Infections

3. ANTIGEN CAPTURE AND PRESENTATION TO LYMPHOCYTES
What Lymphocytes See

4. ANTIGEN RECOGNITION IN THE ADAPTIVE IMMUNE SYSTEM
Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires

5. T CELL–MEDIATED IMMUNITY
Activation of T Lymphocytes by Cell-Associated Antigens

6. EFFECTOR MECHANISMS OF T CELL–MEDIATED IMMUNITY
Functions of T Cells in Host Defense

7. HUMORAL IMMUNE RESPONSES
Activation of B Lymphocytes and Production of Antibodies

8. EFFECTOR MECHANISMS OF HUMORAL IMMUNITY
Elimination of Extracellular Microbes and Toxins

9. IMMUNOLOGICAL TOLERANCE AND AUTOIMMUNITY
Self-Nonself Discrimination in the Immune System and Its Failure

10. IMMUNE RESPONSES AGAINST TUMORS AND TRANSPLANTS
Immunity to Noninfectious Transformed and Foreign Cells

11. HYPERSENSITIVITY
Disorders Caused by Immune Responses

12. CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES
Diseases Caused by Defective Immunity

Selected Readings

Appendix I: Glossary
Appendix II: Cytokines
Appendix III: Principal Features of Selected CD Molecules
Appendix IV: Clinical Cases

Index

Product details

  • Edition: 5
  • Latest edition
  • Published: November 2, 2015
  • Language: English

About the authors

AA

Abul K. Abbas

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California
Affiliations and expertise
Emeritus Professor, Department of Pathology, University of California San Francisco, USA

AL

Andrew H. Lichtman

Andrew H. Lichtman is Professor of Pathology, Brigham and Women's Hospital, Harvard Medical School.
Affiliations and expertise
Professor of Pathology, Brigham and Women's Hospital, Harvard Medical School, USA

SP

Shiv Pillai

Shiv Pillai is Professor of Medicine and Health Sciences and Technology, Harvard Medical School, Ragon Institute of MGH, MIT and Harvard.
Affiliations and expertise
Professor of Medicine and Health Sciences and Technology, Harvard Medical School, Ragon Institute of MGH, MIT and Harvard, USA