Advances in Clinical Chemistry
- 1st Edition, Volume 72 - October 12, 2015
- Latest edition
- Editor: Gregory S. Makowski
- Language: English
Advances in Clinical Chemistry, Volume 72, the latest installment in this internationally acclaimed series contains chapters authored by world-renowned clinical laboratory scient… Read more
Advances in Clinical Chemistry, Volume 72, the latest installment in this internationally acclaimed series contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.
- Contains the expertise of international contributors
- Provides the latest cutting-edge technologies in the field
- Authored by world-renowned clinical laboratory scientists, physicians, and research scientists
Clinical Laboratory Professionals, Physicians and Research Scientists
- Preface
- Chapter One: Metabolic Syndrome and Menopause: Pathophysiology, Clinical and Diagnostic Significance
- Abstract
- 1 Introduction
- 2 Menopause Definition
- 3 MetS in Peri- and Postmenopausal Women
- 4 Effect of Menopause on MetS Components and the Role of Sex Hormones
- 5 Other Biomarkers Related to MetS in Postmenopausal Women
- 6 MetS: A Risk Factor for Diseases Related to Menopause
- 7 Effect of Hormone Replacement Therapy on MetS Components and Cardiovascular Events
- 8 Dietary Patterns and Risk of MetS in Postmenopausal Women
- 9 Association Between Physical Activity and MetS in Postmenopausal Women
- 10 Conclusions
- Chapter Two: Homocysteine in Chronic Kidney Disease
- Abstract
- 1 Introduction
- 2 Causes of Hyperhomocysteinemia
- 3 Homocysteine-Induced Oxidation
- 4 Are Oxidation Reactions the Sole Culprit for Renal Failure?
- 5 Changes in Methylation Pattern
- 6 Redox Switches
- 7 Conclusion
- Chapter Three: Lung Cancer Biomarkers
- Abstract
- 1 Introduction
- 2 Biomarker Development in Biological Fluids (Body Fluids)
- 3 Publication Trend in “Lung Cancer biomarkers”
- 4 Lung Cancer Biomarkers at Limited Clinical Usage
- 5 Lung Cancer Biomarkers in Clinical Trials
- 6 Lung Cancer Biomarkers in Validation Phases
- 7 Circulating Tumor Cells
- 8 Additional Molecular Markers in Other Biological Fluids of Lung Cancer Patients
- 9 Conclusion
- Acknowledgments
- Chapter Four: SEPT9: A Specific Circulating Biomarker for Colorectal Cancer
- Abstract
- 1 Introduction
- 2 The Role of Septin9
- 3 SEPT9 and Colorectal Cancer
- 4 Clinical Applications of SEPT9 Gene Methylation Assay in CRC Detection and Screening
- 5 Conclusions
- Acknowledgments
- Chapter Five: Glycated Serum Albumin and AGE Receptors
- Abstract
- 1 Introduction
- 2 Protein Glycation
- 3 Glycated Serum Albumin—GA
- 4 AGE Receptors
- 5 Glycated Albumin as a Clinical Marker
- 6 Conclusion
- Chapter Six: Polycyclic Aromatic Hydrocarbons: Part I. Exposure
- Abstract
- 1 Introduction
- 2 PAH Distribution and Exposure
- 3 The Concept of Biomarkers
- 4 The Concept of Toxicokinetics
- 5 Toxicokinetics of PAH
- Index
- Edition: 1
- Latest edition
- Volume: 72
- Published: October 12, 2015
- Language: English
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USARead Advances in Clinical Chemistry on ScienceDirect