
Essential Chemistry for Formulators of Semisolid and Liquid Dosages
- 1st Edition - October 15, 2015
- Imprint: Academic Press
- Authors: Vitthal S. Kulkarni, Charles Shaw
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 1 0 2 4 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 1 0 7 2 - 3
A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemis… Read more

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Request a sales quote- Unique coverage of the underlying chemistry that makes possible stable dosages
- Quality content written by experienced experts from the drug development industry
- Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products
- Preface
- Chapter 1. Introduction
- Chapter 2. Surfactants, Lipids, and Surface Chemistry
- 2.1. Introduction
- 2.2. Types of Surfactants
- 2.3. Natural Surfactants
- 2.4. The Role of Surfactants in Pharmaceutical Formulations
- 2.5. Surface Chemistry for Pharmaceutical Formulations
- 2.6. Conclusion
- Chapter 3. Drug Delivery Vehicles
- 3.1. Introduction
- 3.2. Emulsion Drug Delivery Systems
- 3.3. Liposome Drug Delivery Systems
- 3.4. Other Nanodrug Delivery Systems
- 3.5. Conclusion
- Chapter 4. Formulating Creams, Gels, Lotions, and Suspensions
- 4.1. Introduction
- 4.2. Creams and Lotions
- 4.3. Gels, Ointments, and Suspensions
- 4.4. Formulating with Liposomes
- 4.5. Excipients
- 4.6. Conclusion
- Chapter 5. Use of Polymers and Thickeners in Semisolid and Liquid Formulations
- Background
- 5.1. Polymers as Styling Agents
- 5.2. Polymers as Conditioning Agents
- 5.3. Polymers as Preservatives
- 5.4. Polymers as Penetration Enhancers
- 5.5. Polymers as Thickening and Suspending Agents
- 5.6. Characteristics of Commonly Used Thickening, Gelling, and Suspending Agents
- Chapter 6. Aerosols and Nasal Sprays
- 6.1. Aerosols
- 6.2. Nasal Sprays
- Chapter 7. Preparation and Stability Testing
- 7.1. How Formulations Are Put Together
- 7.2. Mixing Systems
- 7.3. Quality by Design (QbD) for Formulation and Process Development
- 7.4. Stability Testing
- Chapter 8. Particle Size Analysis: An Overview of Commonly Applied Methods for Drug Materials and Products
- 8.1. Introduction
- 8.2. Laser Diffraction
- 8.3. Particle Size Evaluation by Microscopy
- 8.4. Conclusion
- Chapter 9. Rheological Studies
- 9.1. General Terms and Definitions
- 9.2. Instruments and Measuring Geometries
- 9.3. Material Behavior
- 9.4. Rheological Studies
- 9.5. Practical Application of Rheological Data
- Chapter 10. Microscopy Techniques
- 10.1. Introduction
- 10.2. Optical Microscopy
- 10.3. Scanning Electron Microscopy
- 10.4. Transmission Electron Microscopy
- 10.5. Atomic Force Microscopy
- 10.6. Conclusion
- Chapter 11. Miscellaneous Physical, Chemical, and Microbiological Test Methods
- 11.1. General Physical Tests
- 11.2. General Chemical Tests
- 11.3. General Microbiological Tests
- 11.4. Product-Specific Tests
- Chapter 12. An Overview of Regulatory Aspects for Pharmaceutical Semisolid Dosages
- 12.1. Quality Data
- 12.2. Types of Regulatory Submissions
- 12.3. Resources—ICH
- 12.4. Resources—FDA
- 12.5. Resources—WHO
- Index
- Edition: 1
- Published: October 15, 2015
- Imprint: Academic Press
- No. of pages: 256
- Language: English
- Hardback ISBN: 9780128010242
- eBook ISBN: 9780128010723
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Vitthal S. Kulkarni
Dr. Kulkarni is experienced in developing and characterizing various non-invasive drug delivery systems including topical drug delivery systems comprised of liposomes, and nano-particles, emulsions and nasal spray products. He has published scientific research articles in peer reviewed journals, patents, book chapters, and edited a book titled Handbook of Non-Invasive Drug Delivery Systems: Science and Technology. He is a current member of American Association of Pharmaceutical Scientists.
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Charles Shaw
Dr. Shaw is experienced in the development and characterization of wound dressings, semi-solid and liquid formulations, and nasal spray products. He has published scientific research articles in peer reviewed journals, book chapters, trade journals and conferences. He has also presented webinars and conference workshops for nasal spray products. He is a current member of American Association of Pharmaceutical Scientists.