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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • The Neostriatum

    Proceedings of a Workshop Sponsored by the European Brain and Behaviour Society, Denmark, 17-19 April 1978
    • 1st Edition
    • Ivan Divac + 1 more
    • English
    The Neostriatum presents the puzzles of the neostriatum from many different angles. This book presents significant findings concerning the structure and neurotransmitters of the neostriatum. Organized into four parts encompassing 20 chapters, this book begins with an overview of the basic organization of the neostriatum. This text then illustrates an impressive complexity of extrinsic and intrinsic neostriatum circuitry. Other chapters consider the view that the nervous system evolved as a hierarchy, so that non-cortical structures such as the corpus striatum retain their structure and function even when the latter is made subservient to more developed mechanisms of the cerebral cortex. This book discusses as well the behavioral roles of the neostriatum and reviews the behavioral data obtained with each of the major treatment and recording techniques. The final chapter deals with the important features of striatal functions. This book is a valuable resource for neuropsychopharmacol... neuropsychologists, neurophysiologists, psychologists, and scientists.

  • Progress in Behavior Modification

    Volume 3
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 3, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The present volume opens with a chapter on behavior modification and hypnosis. This is followed by separate chapters on applications of behavior modification procedures in classroom settings; smoking behavior modification; and psychotherapy outcome research. Subsequent chapters deal with the behavioral approach to teaching learning disabled children; evaluation of animal analogues of behavioral treatment; therapy for sexual dysfunction; and research in the area of transfer of training of operant treatment effects with children.

  • Cerebral Palsy

    A Clinical and Neuropathological Study
    • 1st Edition
    • Erna Christensen + 1 more
    • English
    Cerebral Palsy: A Clinical and Neuropathological Study is an account of a detailed study in which obstetrical, neonatal and neurological investigations on a large group of patients are presented with full neuropathological data found at subsequent necropsy. The book discusses the general autopsy findings and neuropathological techniques; as well as neuropathological findings in the different clinical entities. The text also describes the neuropathological findings and classification; progressive encephalopathies; and epilepsy. Neurologists will find the book invaluable.

  • Comparative Neuropathology

    • 1st Edition
    • J. R. M. Innes + 1 more
    • English
    Comparative Neuropathology focuses on documented accounts of neurologic diseases and congenital defects in animals. The book first offers information on neuropathology, neuroanatomy, and cerebrospinal fluid (CSF). The domesticated animals that have CSF include horses, dogs, pigs, cats, rabbits, and cattle. The text then elaborates on neurologic diseases of apes and monkeys. Discussions focus on confluent leucoencephalosis and perivascular myelosis, encephalopathies and dysenteric syndromes, meningitis, epilepsies, tuberculosis, cerebellar atrophy and experimental manganese poisoning, and choreic syndrome in baboons with corticostriate encephalitis. The publication examines the diseases of the skeletal muscle and hypophysis, including general reactions of muscles to injuries, congenital defects, muscular dystrophies, changes in muscle associated with specific diseases, and tumor. The manuscript also takes a look at inherited diseases and congenital anomalies, protozoan and bacterial infections, and demyelinating or myelinoclastic diseases. The text is a dependable reference for readers interested in comparative neuropathology.

  • A Neurological Study of Newborn Infants

    Clinics in Developmental Medicine, No. 28
    • 1st Edition
    • David J. Beintema
    • English
    A Neurological Study of Newborn Infants considers the consistencies and inconsistencies of neonatal neurological signs. The possibility of a relationship between pre- and perinatal complications of pregnancy and later cerebral dysfunction has led to an increasing interest in the early detection of these defects in the newborn infant. This book is divided into nine chapters, and begins with a presentation of standardized procedures to obtain reliable information from the neurological examination. The next chapters deal with the developmental course of neurological signs during the first days of life. The final chapters discuss the potential effects of obstetrical and postnatal conditions on the developmental course and the consistency of neurological signs throughout the neonatal period. This book is an invaluable source for developmental biologists, neurologists, pediatricians, and obstetricians.

  • Pain Syndromes in Neurology

    Butterworths International Medical Reviews
    • 1st Edition
    • Howard L. Fields
    • English
    Pain Syndromes in Neurology deals with the diagnosis and treatment of painful conditions associated with dysfunction of the peripheral or central nervous system. It discusses advances in three areas: first, the normal anatomy and physiology of pain; second, the pathophysiology of damaged sensory neurons; and third, the diagnosis and treatment of patients with neuropathic pain. The book begins with a discussion of neural mechanisms relevant to pain perception along with a brief review of neuropathic pain. This is followed by separate chapters on hyperalgesia following cutaneous injury; the importance of peripheral processes in the etiology of neuropathic and radiculopathic pain; and mechanisms by which sympathetic efferent fibers contribute to the occurrence of pain. Subsequent chapters cover the diagnosis and treatment of reflex sympathetic dystrophy; pain in generalized neuropathies; surgical treatment of pain; clinical features and management of postherpetic neuralgia; diagnosis of cancer pain syndromes; and drugs in the management of chronic pain.

  • Receptors

    Model Systems and Specific Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

  • Movement Disorders

    Neurology
    • 1st Edition
    • C. David Marsden + 1 more
    • English
    Neurology, Volume 2: Movement Disorders is a part of an international series of critical reviews of topics in neurology. This volume focuses on Parkinsonism and dyskinesia, a condition characterized by abnormal involuntary movements. Organized into 18 chapters, this book first elucidates the problems, causes, pathology, brain neurotransmitter changes and receptors, depression, dementia, fluctuations of disability, and treatment of Parkinson's disease. Subsequent chapters then explore the problems, controversies, and surgical approaches involved in certain dyskinesias. The role of dopamine receptors in movement disorders is also explored. This book will be valuable to neurologists-in-trai... as well as to those in research field or in practice in this field of interest. The book's clinical content will help in the management of patients with movement disorders.

  • Neurological Emergencies

    • 1st Edition
    • S.D. Shorvon
    • English
    Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.

  • The Primary Care of Seizure Disorders

    A Practical Guide to the Evaluation and Comprehensive Management of Seizure Disorders
    • 1st Edition
    • Hugh B. McIntyre
    • English
    The Primary Care of Seizure Disorders: A Practical Guide to the Evaluation and Comprehensive Management of Seizure Disorders is designed to help physicians who in the course of clinical practice care for patients who have epileptic seizures. The intention is to provide a thorough but concise treatment of the subject which may serve as a basic text as well as a handy reference source for solving problems as they arise on a case-by-case basis. The book contains 10 chapters organized according to the sequence which clinical management often follows. These include differential diagnosis and genetic aspects of seizure disorders; the electroencephalograp... evaluation; medical therapy of seizure disorders, including first aid and the treatment of status epilepticus; psychiatric aspects of epilepsy; problems of noncompliance; medical-legal aspects of epilepsy; and finding ancillary, community resources for patients, including voluntary organizations and patient and lay education.

  • Agrammatism

    • 1st Edition
    • Mary-Louise Kean
    • English
    Agrammatism provides an overview of the state of knowledge on agrammatism, typically defined as a disorder of sentence production involving the selective omission of function words and some grammatical endings on words. The book opens with discussions of the diversity of the disorder. This is followed by separate chapters that address primarily questions of syntactic structure in agrammatism, from both linguistic and psycholinguistic perspectives. Within these two gross sections there is no consensus among the conclusions reached by the various authors. However, the position is taken that agrammatism is a disorder distinct from other aphasie disorders of sentence structure. This position is reconsidered in the final two chapters. Because of the intrinsically interdisciplinary character of research on agrammatism, it is hoped that the work presented in this volume will be of interest to linguists and psycholinguists working in areas outside the domain of aphasia, as well as to neurolinguists and neuropsychologists who are already involved in the study of language deficits.

  • Neurologic Emergencies in Infancy and Childhood

    • 2nd Edition
    • John M Pellock + 1 more
    • English
    This second edition of Neurologic Emergencies in Infancy and Childhood is written in response to colleagues who have requested an updated version of the book because of numerous advances in child neurology and medicine in general since the first offering. The chapters were designed for easy use in emergency and general medical situations and all chapters have been revised, rewritten, or replaced. This book is organized into 21 chapters written by 31 contributors. A separate section on spinal cord disorders has greatly expanded the previous chapter on myelomeningocele and it includes a discussion on spinal cord trauma and other causes of paraplegia. A separate chapter on psychiatric emergencies possibly presenting with neurologic signs or symptoms has been added. The chapters also contain information concerning drug dosages and the use of newer agents, including antibiotics, antiepileptics and other drugs. This book will be of interest to persons dealing with studies on the management of neurologic emergencies.

  • Biochemistry of Brain

    • 1st Edition
    • Sudhir Kumar
    • English
    Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids. This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents. This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.

  • Neurobiology of Cytokines

    Methods in Neurosciences, Vol. 16
    • 1st Edition
    • Errol B. De Souza
    • English
    Neurobiology of Cytokines, Part A provides an overview of the effects of cytokines in the brain and in the endocrine system. The book discusses the general aspects of cytokines, including the endogenous agonists and antagonists, their receptors, their second messengers, and transport mechanisms for cytokines across the blood-brain barrier. The text also describes the anatomical localization of cytokines, cytokine receptors, and their respective mRNA in brain and in endocrine tissues. The methods for evaluating the in vivo as well as in vitro actions of cytokines on hormone secretion are also considered. The book further tackles the synthesis and release of cytokines and their central nervous system actions; and the methodology for studying the role of cytokines in human neuropathological conditions.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 2, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in mollusks. The book contains four chapters and begins with a discussion of neural control of cephalopod behavior. Subsequent chapters deal with the neuroanatomy of selected gastropod species; molluscan membranes, gates, and channels; and molluscan transmitters and modulators.

  • Brain Receptor Methodologies

    Amino Acids. Peptides. Psychoactive Drugs
    • 1st Edition
    • Paul J. Marangos + 2 more
    • English
    Brain Receptor Methodologies: Part B Amino Acids. Peptides. Psychoactive Drugs is the second of the two-part first volume of the Neurobiological Research series, which provides a comprehensive view of various subdisciplines within neurobiology. The first volume (Parts A and B) deals with the area of neurotransmitter and neuromodulator receptors in brain; future volumes will cover the subdisciplines of neuroanatomy, neurophysiology, brain-specific macromolecules, neurochemistry, and behavioral neurobiology. It is hoped that the series will be of equal value for both basic as well as clinical scientists Part B continues from Part A with the remainder of Section II, specific receptor binding methodologies. Subsection II,B deals with receptors for amino acids and neuropeptides and covers areas including GABA, glycine, carnosine, opiates, bombesin, CCK, TRH, and substance P. Amino acids probably represent the majority of brain neurotransmitter substances, at least relative to the amines and acetylcholine, although with the exception of GABA, the amino acids remain relatively uncharacterized in brain. Their further study should receive high priority.

  • Models of Human Memory

    • 1st Edition
    • Donald A. Norman
    • English
    Models of Human Memory provides an overview of the state of knowledge on human memory models. The book begins with an introductory chapter on the basic stages of the memory system and the historical roots of memory models. The remaining chapters are organized into five parts. Part I on memory systems covers topics such as a system for perception and memory; multi-trace strength theory of memory; and a model for postperceptual verbal memory that postulates a single memory store, with multiple copies, called replicas, created in memory by rehearsal processes. Part II presents studies phoneme storage and word recognition. Part III on memory for associations examines the storage-retrieval theory for the memorizing processes and presents simple model of short-term memory (STM) for paired associates. Part IV on storage and retrieval mechanisms deals with mechanisms of repetition and rehearsal in short-term memory; models of recall and recognition; and memory search models. Part V presents a theory of human long-term associative memory; and examines conceptual and methodological interactions between information-processi... investigations of cognitive activity and attempts to build models of memory.

  • Neuropeptide Technology

    Gene Expression and Neuropeptide Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 5: Neuropeptide Technology: Gene Expression and Neuropeptide Receptors discusses procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into two sections—neuropeptid... gene expression and neuropeptide receptors. In these sections, this book specifically discusses the assays for peptide products of somatostatin gene expression; molecular assays for rat thyrotropin-releasin... hormone gene; and structure, expression, and chromosomal localization of human gene. The gastrin-releasing peptide or mammalian bombesin; semiquantitative analysis of cellular somatostatin mRNA Levels; and atrial natriuretic factor receptor assays are also elaborated. This text likewise covers the receptors for opioid peptides in brain and autoradiography of somatostatin receptors in rat cerebellum. This publication is beneficial to neuroscientists and students intending to acquire knowledge of gene expression and neuropeptide receptors.

  • Neurobiology of Motor Programme Selection

    New Approaches to the Study of Behavioural Choice
    • 1st Edition
    • J. Kien + 2 more
    • English
    The traditional view of motor systems as a linear chain of elements switched on and off by command neurons has become increasingly difficult to maintain in the face of accumulating evidence against the existence of command elements. So far, however, the general formulation of an alternative approach has been lacking. This book, by summarising the evidence against the linear approach to motor systems, argues forcefully against it. Analyses are presented of motor systems ranging from the lobster stomatogastric system through molluscan systems, leech movement, insect singing and locomotion, fish and amphibian behaviour, to goal-directed a movements in primates and volitional movements in humans. Comparison of these motor systems reveal the existence of some general principles underlying motor control and behavioural choice such that motor systems appear generally to be parallel, distributed processing networks. By discussing the treatment of motor systems in terms of parallel distributed processing systems, this book presents in concentrated form an alternative to the earlier view of motor systems. As such, the book is a must for all neuroscientists interested in the organisation of motor systems and the neuronal substrates of behavioural choice.

  • Progress in Neurology and Psychiatry

    An Annual Review
    • 1st Edition
    • E. A. Spiegel
    • English
    Progress in Neurology and Psychiatry: An Annual Review, Volume 22 covers the significant advances in the understanding of neurophysiology, neuro-ophthalmology, and psychiatry. This volume is organized into four sections encompassing 33 chapters that also deal with the neurological aspects of pain and motor disorders. The first part discusses the fundamentals of neuroanatomy, general and regional neurophysiology, neuropathology, and the pharmacological aspects of the central nervous system. The second part examines the diagnosis, symptoms, and clinical features of neurological disorders. This part also explores the anatomical aspects of neuro-ophthalmology, otoneurology, and pediatric neurology. The third part reviews the surgical treatments for various neuro-related problems, including trauma, brain tumors, pain, and motor disorders. The fourth part considers the application of clinical psychiatry to the diagnosis and treatment of mental and emotional disorders, both in children and adults. This book will prove useful to neurologists, clinicians, pediatricians, and psychiatrists.

  • British Surgical Practice

    Abdominal Emergencies to Autonomic Nervous System
    • 1st Edition
    • Ernest Rock Carling + 1 more
    • English
    British Surgical Practice, Volume I describes the diagnosis, physiology, symptoms, treatment, and appropriate surgical procedure of various health problems. This book is composed of 45 chapters, and begins with discussions on the available treatment and surgical options for abdominal problems, abortion, formation of abscess, achlorhydria, acidosis, actinomycosis, and pulmonary tuberculosis. Other chapters describe the clinical features and surgical treatments for other medical conditions, including allergy, amebiasis, amputations, amyloidosis, angina pectoris, and angioma. Considerable chapters explore the fundamentals and principles of post-operative methods and surgical anesthesia. The concluding chapters consider the surgical options for anus problems, anxiety states, appendicitis, arthritis, and artery and autonomic nervous problems. Surgeons, physicians, and medical personnel will find this book invaluable.

  • The Study of Behavioral Development

    • 1st Edition
    • Joachim F. Wohlwill
    • David S. Palermo
    • English
    The Child Psychology Series: The Study of Behavioral Development concerns the formulation of general laws of development, transcending the realm of the development of the individual from infancy to maturity. This book provides a systematic treatment of problems of research design, strategy, and data analysis that relate specifically to the study of developmental changes in behavior. The topics discussed include developmental psychology in the 1970s, age variable in psychological research, and programmatic view of the task of developmental psychology. The problems of measurement and quantification in developmental psychology, correlational methods in the study of developmental change, and experimental manipulation of developmental change are also elaborated. This publication is recommended for psychologists, specialists, and students learning the nature of behavioral change.

  • Applied Neurophysiology

    With Particular Reference to Anaesthesia
    • 1st Edition
    • J.A. Simpson + 1 more
    • English
    Applied Neurophysiology is intended to promote understanding of the structure and function of the human nervous system for anesthetists. For that reason this book presented concepts rather than critical discussions of experimental work. This book is organized into five parts. There are chapters intended for specialists such as those on vision, control of gaze, hearing and locomotion that were included in order to introduce concepts on brain stem automatisms and cortical function necessary to understand respiration and conscious awareness. There is also a chapter on autonomic nervous system which provides an account of the regulation of the cerebral circulation. The final sections of this volume also include quantitative data and references to original studies which were not thought necessary in other sections. This book will be of interest to anesthetists, clinicians, psychologists, speech pathologists and even neurologists in training.

  • Ion Channels of Excitable Cells

    • 1st Edition
    • Volume 19
    • P. Michael Conn + 1 more
    • English
    Because of the highly significant and widely recognized roles of ion channels in physiology, pathophysiology, pharmacology, and toxicology, the term ion channel has now become a household word in the biomedical sciences. This volume covers preparations and techniques for the study of various ion channels. Both voltage-gated and ligand-gated ion channels of neurons, axons, and cardiac and smooth muscles are covered. It includes not only patch clamp techniques but molecular biology and imaging techniques as well.

  • Neural Modeling and Neural Networks

    • 1st Edition
    • F. Ventriglia
    • English
    Research in neural modeling and neural networks has escalated dramatically in the last decade, acquiring along the way terms and concepts, such as learning, memory, perception, recognition, which are the basis of neuropsychology. Nevertheless, for many, neural modeling remains controversial in its purported ability to describe brain activity. The difficulties in "modeling" are various, but arise principally in identifying those elements that are fundamental for the expression (and description) of superior neural activity. This is complicated by our incomplete knowledge of neural structures and functions, at the cellular and population levels. The first step towards enhanced appreciation of the value of neural modeling and neural networks is to be aware of what has been achieved in this multidisciplinary field of research. This book sets out to create such awareness. Leading experts develop in twelve chapters the key topics of neural structures and functions, dynamics of single neurons, oscillations in groups of neurons, randomness and chaos in neural activity, (statistical) dynamics of neural networks, learning, memory and pattern recognition.

  • Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses

    Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27-29, 1981
    • 1st Edition
    • P. Lechat + 2 more
    • English
    Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on July 27-29, 1981. The book contains papers on the effects of aminopyridines on ionic currents in excitable membranes; the effects of aminopyridines on synaptic transmission; and the effects of aminopyridines on the release of chemical transmitters. The text also presents papers on some differences in the blockade of potassium permeabilities by apamin and the aminopyridines; the miscellaneous actions of aminopyridines and related compounds; and the effects of aminopyridines on the skeletal, smooth and cardiac muscle. The clinical applications of aminopyridines and further miscellaneous actions of aminopyridines and related compounds are also considered.

  • Biological Markers in Psychiatry and Neurology

    Proceedings of a Conference Held at the Ochsner Clinic, New Orleans, on May 8-10, 1981
    • 1st Edition
    • Earl Usdin + 1 more
    • English
    Biological Markers in Psychiatry and Neurology is a collection of papers that details the advancement in the understanding of the biological markers that stems from psychiatric and neurological pathologies. The text first covers topics about various biological markers, such as neurochemical, enzymatic, membrane, receptors, endocrine, and physiological. Next, the selection examines the relationship between alcohol abuse and biological papers. The next part covers the genetic aspects of biological markers. The text also deals with use of tomography and modeling theory. The book will be of great use to students, researchers, and practitioners of neurology and psychiatry. Psychologists will also benefit from the text.

  • Atlas of the Prenatal Mouse Brain

    • 1st Edition
    • Uta B. Schambra + 1 more
    • English
    The Atlas of the Prenatal Mouse Brain is the latest addition to Academic Press' list of atlases for neuroscientists and neuroscience students. It fills an urgent need for a comprehensive atlas of the developing mouse brain for use in studies of both normal and abnormal development. High-quality photomicrographs of brain sections are depicted in sagittal, coronal, and horizontal planes for four gestational age groups. Each photomicrograph is accompanied by a fully labeled, precision-drawn diagram for easy identification of brain structures. Researchers and students using normal, transgenic, or mutant mouse preparations in developmental neurobiology, neurotoxicology, and biotechnology will welcome this meticulously assembled and accessible guide.

  • Neurotrauma

    Treatment, Rehabilitation, and Related Issues
    • 1st Edition
    • Michael E. Miner + 1 more
    • English
    Neurotrauma features the papers presented at the Second Houston Conference on Neurotrauma in Texas held in May 1985. These papers cover discussions on patients who have both brain and spinal cord injuries and acute care treatment and investigations of brain injury, as well as rehabilitation strategies and approaches. This second edition is organized into four parts. The first part deals with the treatment of less-than-severe head injury, barbiturate-induced coma, closed head injuries, and severely brain-injured patients. The second part focuses on the evaluation of physiological and anatomical recovery of brain injury patients, while the third part discusses the management of patients with combined head and spinal cord injury. The final part focuses on rehabilitation issues that include nonpharmacological management, the impact of traumatic brain injury on sexuality, and ethical aspects of lifesaving therapeutic strategies. This book may be of interest to persons dealing with studies on the treatment of brain and spinal cord injuries.

  • Neurogenic Heart Lesions

    • 1st Edition
    • I. S. Zavodskaya + 2 more
    • English
    Neurogenic Heart Lesions reviews the main publications concerned with the problem of neurogenic lesions of the heart. The book describes the methods for producing experimental neurogenic lesions, as well as the pharmacological analysis of the participation of the sympathetic nervous system and its transmitters in the development of neurogenic lesions of the myocardium. The text also discusses the changes in energy metabolism and in functional conditions of the myocardium caused by neurogenic lesions; and the pharmacoprophylaxis and pharmacotherapy of the biochemical changes produced by neurogenic lesions of the myocardium. Pharmacologists, pathologists, and other clinicians and physicians concerned with the new achievements in the field of cardiology will find the book invaluable.

  • Principles and Practice of Restorative Neurology

    Butterworths International Medical Reviews
    • 1st Edition
    • Robert R Young + 1 more
    • English
    Principles and Practice of Restorative Neurology is a collection of topics in clinical neurology where progress through research has brought concepts of patient management. The collection emphasizes research done clinically and in experimental laboratories and attempts to discuss restorative neurology in the larger context, encompassing biology, neurobiology, and rehabilitative engineering. The book discusses the concept that neurology should be more therapeutic instead of being just diagnostic because of advances in techniques and drugs. An epidemiology of disability and the evaluation of restorative neurology are explained. The text also presents the developments in the pharmacotherapy of major neurological disorders, such as Parkinson's disease, dementia, and stroke. The use of biomechanical or rehabilitation engineering to treat impaired or lost functions in a patient is compared; the feedback mechanisms and the kinds of treatment including microsurgery, nuerostimulation methods, surgery, and molecular genetics that are applied to specific disorders are discussed extensively. The book also reviews the approaches of gene correction for disorders in the central nervous system. Finally, the future needs of neurology in terms of diagnosis and treatments are dealt with as more research, techniques, and drugs are being discovered and proved useful. The collection is intended for neurologists, neurologists in training, and other physicians whose work lies with neurological disorders. The book can also prove useful for practitioners and academicians in the fields of neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • An Introduction to the Study of the Nervous System

    • 2nd Edition
    • E. E. Hewer + 1 more
    • English
    An Introduction to the Study of the Nervous System covers topics about the minute structure and functions of the nervous system. The book discusses the minute and gross anatomy of the various parts of the nervous system; the degenerative and regenerative changes following section of the nerves; and the descending and ascending tracts of the spinal cord. The text then describes the cerebellar connections; the deep connections of the cranial nerves; and the microscopic structure of the cortex of the cerebellum and of the cerebrum. The distribution, source, circulation and absorption, pressure, and normal composition of the cerebrospinal fluid and the parts and functions of the autonomic nervous system are also considered. The book further tackles the normal physiology of the sensory and motor paths; the results of interference with the general sensory path at various levels; and the visual path and interference therewith. The text also discusses the cochlear and olfactory paths and the interference therewith and the levels of integration and mechanism of coordinated muscular movement. Students taking courses related to neurology will find the book useful.

  • Cognitive Development

    The Child's Acquisition of Diagonality
    • 1st Edition
    • David R. Olson
    • David S. Palermo
    • English
    Cognitive Development: The Child's Acquisition of Diagonality is an empirical and rational enquiry into the child's development of a conceptual system relating to the concept of the diagonal during the age range three to six years. A detailed examination will be made of why a young child has difficulty with such a problem, and what occurs during development that removes this difficulty. In the context of these empirical arguments, the book considers such theoretical questions as the nature of intellectual skills and conceptual or symbolic knowledge, as well as the role of experience and instruction in their development. The study concludes with a description of the child's reconstruction of the diagonal in terms of what at least poses as a general model of perceptual and intellectual development, and accounts for, among other things, man's increasing ability to apprehend and theorize about the motion of the stars. It shows that it is the elaboration of the child's perceptual knowledge in the context of his performatory attempts in such cultural media as language and geometry that accounts for his ability to copy a diagonal in particular and his intellectual development in general.

  • Receptors in the Human Nervous System

    • 1st Edition
    • F. A. O. Mendelsohn + 1 more
    • English
    Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.

  • Neurotrauma

    Treatment, Rehabilitation, and Related Issues
    • 1st Edition
    • Michael E. Miner + 1 more
    • English
    Neurotrauma: Treatment, Rehabilitation, and Related Issues discusses the issues pertinent to central nervous system trauma. This book is organized into three parts encompassing 17 chapters that tackle the study and management of head injury, including the range of treatment, rehabilitation, and reintegration into the community. Some of the topics covered in the book are the demography of head injury in the United States; cardiopulmonary changes after head injury; management of intracranial hypertension; mechanisms and management of posttraumatic epilepsy; metabolic responses to severe head damage; and evoked responses monitoring in the intensive care unit. Other chapters deal with the auditory assessment of neural trauma, the issues in the evaluation of rehabilitation effects, and the sociological parameters affecting comparisons of long-term outcome. A chapter is devoted to the sensory evoked responses in the diagnosis of brain death. The final chapter focuses on the outcome and recovery of children after experiencing head injury. The book can provide useful information to doctors, neurologists, students, and researchers.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 1, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs. The book contains four chapters and begins with a chapter on the behavior of gastropod mollusks. Subsequent chapters deal with learning in gastropod mollusks, the neuronal control of behavior in gastropods, and the development and plasticity of molluscan neurons.

  • Neurotoxins

    • 1st Edition
    • Volume 8
    • P. Michael Conn
    • English
    The exquisite simplicity and potency of toxins have made them valuable probes of neural systems. This book presents a comprehensive compilation of techniques used for the preparation, handling, and, particularly, for the use of neurotoxins. Model systems are described in which these neurotoxins have been extremely valuable in developing an understanding of the cellular and molecular basis of secretion and electrophysiological events leading to altered cell function.

  • Neuropathology

    Brussels, 21-28 July 1957
    • 1st Edition
    • L. Van Bogaert + 1 more
    • English
    Neuropathology, Volume IV presents the proceedings of the First International Congress of Neurological Sciences, held in Brussels, Belgium, on July 21–28, 1957. This book provides information pertinent to the fundamental aspects of neuropathology. Organized into 84 chapters, this compilation of papers begins with an overview of the problem of multiple sclerosis and its relationship to leucodystrophies. This text then explains the two major histopathological manifestations of the injury caused by the rabies virus in the central nervous system. Other chapters consider the successful identification and isolation of a biologically active compound, which depends to a large extent on the availability of a quantitative bioassay. This book discusses as well the clinical manifestations, pathogenesis, and treatment of multiple sclerosis. The final chapter deals with the study of nucleic acids as well as histochemistry as a method of histological inquiry. This book is a valuable resource for neuropsychiatrists, biochemists, physicians, and scientists.

  • Selected Topics from Neurochemistry

    • 1st Edition
    • Neville N. Osborne
    • English
    This book contains up-dated versions of articles which proved very popular when first published in Neurochemistry International. The articles draw attention to developments in a specific field perhaps unfamiliar to the reader, collating observations from a wide area which seem to point in a new direction, giving the author's personal view on a controversial topic, or directing soundly based criticism at some widely held dogma or widely used technique in the neurosciences.

  • Comparative Neurochemistry

    Proceedings of the Fifth International Neurochemical Symposium
    • 1st Edition
    • Derek Richter
    • English
    Comparative Neurochemistry, a collection of papers presented at the Fifth International Symposium of Comparative Neurochemistry, held at St. Wolfgang, Austria in 1962, deals with variations in neurochemical mechanisms in different animal species. The book integrates the data derived from comparative studies in different disciplines and assesses their significance in relation to the understanding of nervous mechanisms in animals, including human. The papers are grouped into sections, which cover general topics on functional organization in different species; lipids, proteins, and ribonucleic acid; amino acids in different species; energy metabolism and function; neurosecretory mechanisms; and comparative neuropharmacology. The text will be of interest to biologists, zoologists, pharmacologists, chemists, neurologists, and researchers in the pharmaceutical and chemical industries.

  • Methods in Neurotransmitter and Neuropeptide Research

    • 1st Edition
    • Volume 11
    • S.H. Parvez + 2 more
    • English
    This two-part book provides the most advanced biochemical and histochemical analytical methods on neurotransmitters, neuromodulators, and neuropeptides described by international specialists. The biochemical methods include liquid chromatography/elect... liquid chromatography/fluor... and chemiluminescence detection, gas chromatography or liquid chromatography with mass spectrometry, and immunoassays.Morphol... and physiological methods are also described, including immunohistochemistry... in situ hybridization, in vivo microdialysis, electrophysiological analysis, microwave irradiation, electrophysiological analysis, micro-anatomical dissection, peptide sequence analysis, quantitative autoradiographic analysis, and isolated CNS preparations. The neurotransmitters and neuropeptides include catecholamines, indoleamines, histamine, polyamines, and various neuropeptides, and their related enzymes. The book is the most comprehensive, advanced and versatile volume on the biochemical, morphological and physiological analysis of neurotransmitters and neuropeptides.

  • Biochemical Factors Concerned in the Functional Activity of the Nervous System

    First International Meeting of the International Society for Neurochemistry, Strasbourg, 1967
    • 1st Edition
    • D. Richter
    • English
    Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phosphol... complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin... and tyrosine–noradrenali... systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

  • The Catecholamines in Psychiatric and Neurologic Disorders

    • 1st Edition
    • C. Raymond Lake + 1 more
    • English
    The Catecholamines in Psychiatric and Neurologic Disorders focuses on the contributions of catecholamines (CA) in the modulation of blood pressure, stress and exercise, body movements, memory, learning, emotions, thought processing, appetite, and mediation of psychotropic drug action. The selection first elaborates on the techniques for the assessment and interpretation of catecholamine measurements in neuropsychiatric patients and catecholaminergic response to stress and exercise. Discussions focus on noradrenergic response to isometric exercise, isotonic exercise, effect of acceleration on sympathetic activity, techniques for sympathetic nervous system evaluation, and measurements of CA and their metabolites in cerebrospinal fluid. The text then takes a look at urinary CA in behavioral research on stress; CA in anxiety disorders and mitral valve prolapse; and interaction with neurotransmitters in normal subjects and in patients with selected neurologic diseases. The selection examines noradrenergic responses in postural hypotension, norepinephrine, alcohol, and alcoholism, and catecholamine metabolism in anorexia nervosa. Topics include cerebral catecholamine metabolism in anorexia nervosa; central nervous system norepinephrine and voluntary alcohol drinking; and overview of norepinephrine in selected pediatric disorders. The book is a dependable reference for neuropsychiatrists and readers interested in the contributions of catecholamines on psychiatric disorders.

  • Biophysical Aspects of Cerebral Circulation

    • 1st Edition
    • Yu. E. Moskalenko + 2 more
    • English
    Biophysical Aspects of Cerebral Circulation provides a comprehensive review of the cerebral circulatory system. This book consists of four chapters. Chapter 1 is devoted to methodology attempts to explain the special features of a biophysical approach. The biophysical principles of the most commonly used modem methods such as the clearance method and rheoencephalography are described in detail. The second and third chapters examine all the biophysical aspects of the cerebral circulatory system as a functional unit and deal with some principles of its regulation. The results of systems analysis using mathematical modeling are presented in broad outline. Chapter 4 deals with processes related to the regional cerebral circulation. Such investigations focus mainly on the relationship between periodically fluctuating factors affecting limited areas of brain tissue. This text is beneficial to medical students and individuals researching on cerebral circulation.

  • Progress in Behavior Modification

    Volume 6
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 6, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The book opens with a chapter on the various behavioral procedures for treating insomnia. This is followed by separate chapters on behavioral analysis and formulation of the problem of stuttering; the assessment and treatment of enuresis and encopresis in children; and the development of behavior modification in Latin America. Subsequent chapters deal with the analysis of behavior modification from the point of view of its social identity; the conceptual and clinical literature resulting from the broader emphasis in behavior modification; and the relationship between therapist and client.

  • Excitation and Inhibition

    Synaptic Morphology
    • 1st Edition
    • Koji Uchizono
    • English
    Excitation and Inhibition: Synaptic Morphology proposes the S-F hypothesis that emphasizes the relationship between structure and function of synapses. This book begins with an introduction to the notion of inhibition in the physiology of the nervous system and history of “synapse”, followed by a discussion on the development of concept and morphological correlates of excitation and inhibition in relation to the S-F hypothesis. The mechanism of synaptic excitation and inhibition, physiological classification of neurons, and release mechanism of transmitters are also elaborated. This text describes the synaptic vesicles as a basis of transmitter, membrane recycle, transmission in the sympathetic ganglion, and transmitter substance. The criticism of S-F hypothesis, which deliberates the skeptical investigations of specialists regarding the simplicity and immaturity of the S-F hypothesis of synaptic morphology are provided at the end. This publication is beneficial to medical students and practitioners aiming to acquire knowledge of the physiology of synapses.

  • Visual and Oculomotor Functions

    Advances in Eye Movement Research
    • 1st Edition
    • Volume 5
    • G. d'Ydewalle + 1 more
    • English
    A collection of contemporary work in various areas of eye-movement research with an emphasis on physiological aspects is presented in this book. The contributions are divided into six sections: I. saccadic eye movements; II. smooth pursuit and motion perception; III. eye movements in pathology and clinical settings; IV. neurophysiology of eye movements; V. optokinetic nystagmus; and VI. methods. This volume provides updated information on the most recent research on eye movements carried out mainly in Europe.

  • Neurochemistry of the Retina

    Proceedings of the International Symposium on the Neurochemistry of the Retina Held in Athens, Greece, August 28 - September 1, 1979
    • 1st Edition
    • Nicolas G. Bazan + 1 more
    • English
    Neurochemistry of the Retina covers the proceedings of the International Symposium on the Neurochemistry of the Retina held in Athens, Greece, on August 28 – September 1, 1979. This book mainly focuses on the retina and its neurochemistry. This text is divided into eight major parts. The first part discusses the composition, metabolism, and biogenesis of membrane components. This book then explains the biochemical approaches to the study of visual cells and their relationship with the pigment epithelium, photorector shedding, and circadian rhythm. Chemical transmission of nerve signals is also tackled. This text also looks into the biochemical aspects of photoreceptor structure and function; cyclic nucleotides; and biochemical and pharmacological approaches to study the entire retina. This book concludes by explaining the neurochemical studies in retinal diseases and future research and prospective of the subject. This publication will be invaluable to ophthalmologists and students of ophthalmology.

  • Microsurgery

    Applied to Neurosurgery
    • 1st Edition
    • M. G. Yaşargil
    • English
    Microsurgery Applied to Neurosurgery focuses on microsurgical approaches to cerebrospinal lesions, including plastic surgery, suturing techniques, instruments for microsurgery, and microsurgical operations. The manuscript first offers information on the history of microsurgery and the operating microscope. Discussions focus on bipolar electric coagulation, plastic surgery, peripheral nerves, clinical application, binocular diploscope, automatic microscope stand, sterile covering of the microscope, and magnification. The text also elaborates on the instruments for microsurgery and suturing techniques. The publication takes a look at experimental microsurgical operations in animals and reconstructive and constructive surgery of the cerebral arteries in man. The manuscript also ponders on intracranial tumors and transnasal-transsphe... approach to the pituitary gland. Topics include transsphenoidal approach, suboccipital transmeatal approach, spinal tumors, and preoperative radiological study. The manuscript is a dependable reference for health professionals and readers interested in microsurgery.

  • Studies in Neurolinguistics

    • 1st Edition
    • Haiganoosh Whitaker + 1 more
    • English
    Studies in Neurolinguistics, Volume 3 presents detailed case histories, multi-subject experimental studies, literature reviews, and research papers that employ a variety of experimental and observational techniques. This volume contains seven chapters that focus on a wide range of research in the field of neurolinguistics. Chapter 1 discusses the various approaches to the problem of auditory comprehension in aphasia. A survey of the world's literature on bilingualism and aphasia is provided in chapter 2. The third chapter examines the different models and explanations for conduction aphasia. Chapter 4 provides a synthesis of the anatomic, physiologic, and behavioral research on the role of the limbic system in human communication. Chapter 5 presents a model of individual differences in hemispheric functioning, in which a number of theories about the left and right hemispheres are analyzed and compared. Chapter 6 shows how different levels of language are revealed. The last chapter addresses "The Question of Electrophysiological Asymmetries Preceding Speech" in a study of the readiness potentials over the motor and premotor regions in eight subjects. Linguists, psychologists, and neurologists will find the book highly informative.

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